1.
Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9
by Doench, John G
Nature biotechnology, 2016, Vol.34 (2), p.184-191
2.
Engineered Cpf1 variants with altered PAM specificities
by Gao, Linyi
Nature biotechnology, 2017, Vol.35 (8), p.789-792
3.
DNA targeting specificity of RNA-guided Cas9 nucleases
by Hsu, Patrick D
Nature biotechnology, 2013, Vol.31 (9), p.827-832
4.
DNA-free genome editing in plants with preassembled CRISPR-Cas9 ribonucleoproteins
by Woo, Je Wook
Nature biotechnology, 2015, Vol.33 (11), p.1162-1164
5.
ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering
by Gaj, Thomas
Trends in biotechnology (Regular ed.), 2013, Vol.31 (7), p.397-405
6.
Cre-dependent selection yields AAV variants for widespread gene transfer to the adult brain
by Deverman, Benjamin E
Nature biotechnology, 2016, Vol.34 (2), p.204-209
7.
Increasing the efficiency of homology-directed repair for CRISPR-Cas9-induced precise gene editing in mammalian cells
by Chu, Van Trung
Nature biotechnology, 2015, Vol.33 (5), p.543-548
8.
CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering
by Mali, Prashant
Nature biotechnology, 2013, Vol.31 (9), p.833-838
9.
High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity
by Pattanayak, Vikram
Nature biotechnology, 2013, Vol.31 (9), p.839-843
10.
Targeted genome engineering in human cells with the Cas9 RNA-guided endonuclease
by Cho, Seung Woo
Nature biotechnology, 2013, Vol.31 (3), p.230-232
11.
RNA-guided editing of bacterial genomes using CRISPR-Cas systems
by Jiang, Wenyan
Nature biotechnology, 2013, Vol.31 (3), p.233-239
12.
Increasing the efficiency of precise genome editing with CRISPR-Cas9 by inhibition of nonhomologous end joining
by Maruyama, Takeshi
Nature biotechnology, 2015, Vol.33 (5), p.538-542
13.
Functional genetic screens for enhancer elements in the human genome using CRISPR-Cas9
by Korkmaz, G
Nature biotechnology, 2016, Vol.34 (2), p.192-198
14.
Targeted DNA demethylation in vivo using dCas9-peptide repeat and scFv-TET1 catalytic domain fusions
by Morita, Sumiyo
Nature biotechnology, 2016, Vol.34 (10), p.1060-1065
15.
Photoactivatable CRISPR-Cas9 for optogenetic genome editing
by Nihongaki, Yuta
Nature biotechnology, 2015, Vol.33 (7), p.755-760
16.
Clonal seeds from hybrid rice by simultaneous genome engineering of meiosis and fertilization genes
by Wang, Chun
Nature biotechnology, 2019, Vol.37 (3), p.283-286
17.
Chemically modified guide RNAs enhance CRISPR-Cas genome editing in human primary cells
by Hendel, Ayal
Nature biotechnology, 2015, Vol.33 (9), p.985-989
18.
Large-scale design of robust genetic circuits with multiple inputs and outputs for mammalian cells
by Weinberg, Benjamin H
Nature biotechnology, 2017, Vol.35 (5), p.453-462
19.
CRISPR-Cas systems for editing, regulating and targeting genomes
by Sander, Jeffry D
Nature biotechnology, 2014, Vol.32 (4), p.347-355
20.
Engineering Plastid Genomes: Methods, Tools, and Applications in Basic Research and Biotechnology
by Bock, Ralph
Annual review of plant biology, 2015, Vol.66 (1), p.211-241
