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Designing small molecules to target cryptic pockets yields both positive and negative allosteric modulators.
by Hart, Kathryn M
PloS one, 2017, Vol.12(6), p.e0178678

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Directed Chemical Evolution with an Outsized Genetic Code.
by Krusemark, Casey J
PloS one, 2016, Vol.11(8), p.e0154765

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Preparation of Small-Molecule Microarrays by trans-Cyclooctene Tetrazine Ligation and Their Application in the High-Throughput Screening of Protein-Protein Interaction Inhibitors o...
by Zhang, Chong-Jing
Angewandte Chemie (International Edition), Dec 2013, Vol.52(52), pp.14060-14064

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Design, synthesis and decoration of molecular scaffolds for exploitation in the production of alkaloid-like libraries
by Craven, Philip
Bioorganic & Medicinal Chemistry, 01 June 2015, Vol.23(11), pp.2629-2635

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A High Throughput Screening Assay for Anti-Mycobacterial Small Molecules Based on Adenylate Kinase Release as a Reporter of Cell Lysis
by Forbes, Lauren
PloS one, 2015, Vol.10(6), pp.e0129234

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Small molecule-assisted, line-independent maintenance of human pluripotent stem cells in defined conditions
by Frank, Stefan
PloS one, 2012, Vol.7(7), pp.e41958

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Average Information Content Maximization--A New Approach for Fingerprint Hybridization and Reduction.
by Śmieja, Marek
PloS one, 2016, Vol.11(1), p.e0146666

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A molecular dynamics-based algorithm for evaluating the glycosaminoglycan mimicking potential of synthetic, homogenous, sulfated small molecules.
by Nagarajan, Balaji
PloS one, 2017, Vol.12(2), p.e0171619

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Targeting Epithelial-Mesenchymal Transition for Identification of Inhibitors for Pancreatic Cancer Cell Invasion and Tumor Spheres Formation
by Polireddy, Kishore
PloS one, 2016, Vol.11(10), pp.e0164811

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A Novel Class of Small Molecule Agonists with Preference for Human over Mouse TLR4 Activation.
by Marshall, Jason D
PloS one, 2016, Vol.11(10), p.e0164632

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Large-scale bioactivity analysis of the small-molecule assayed proteome
by Backman, Tyler William H
PloS one, 2017, Vol.12(2), pp.e0171413

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SPR-based fragment screening with neurotensin receptor 1 generates novel small molecule ligands
by Huber, Sylwia
PloS one, 2017, Vol.12(5), pp.e0175842

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A small molecule screen identifies in vivo modulators of peripheral nerve regeneration in zebrafish.
by Bremer, Juliane
PloS one, 2017, Vol.12(6), p.e0178854

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Diversity-Oriented Synthesis of Macrocycle Libraries for Drug Discovery and Chemical Biology
by Collins, Súil
Synthesis, 2016, Vol.48(10)

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A computational strategy for finding novel targets and therapeutic compounds for opioid dependence.
by Wu, Xiaojun
PloS one, 2018, Vol.13(11), p.e0207027

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Identification and characterization of sebaceous gland atrophy-sparing DGAT1 inhibitors.
by Muise, Eric S
PloS one, 2014, Vol.9(2), p.e88908

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Does chemistry have a future in therapeutic innovations?
by Meunier, Bernard
Angewandte Chemie (International ed. in English), August 27, 2012, Vol.51(35), pp.8702-8706
