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Risk Profiles and Treatment Patterns Among Men Diagnosed as Having Prostate Cancer and a Prostate-Specific Antigen Level Below 4.0 ng/mL

BACKGROUND Despite controversy over the benefit of prostate-specific antigen (PSA) screening, little is known about risk profiles and treatment patterns in men diagnosed as having prostate cancer who have a PSA value less than or equal to 4.0 ng/mL. METHODS We used data from the Surveillance, Epidem... Full description

Journal Title: Archives of Internal Medicine 26 July 2010, Vol.170(14)
Main Author: Shao, Yu-Hsuan
Other Authors: Albertsen, Peter C , Roberts, Calpurnyia B , Lin, Yong , Mehta, Amit R , Stein, Mark N , Dipaola, Robert S , Lu-Yao, Grace L
Format: Electronic Article Electronic Article
Language: English
Subjects:
ID: ISSN: 0003-9926 ; E-ISSN: 1538-3679 ; DOI: 10.1001/archinternmed.2010.221
Link: http://dx.doi.org/10.1001/archinternmed.2010.221
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recordid: ama225813
title: Risk Profiles and Treatment Patterns Among Men Diagnosed as Having Prostate Cancer and a Prostate-Specific Antigen Level Below 4.0 ng/mL
format: Article
creator:
  • Shao, Yu-Hsuan
  • Albertsen, Peter C
  • Roberts, Calpurnyia B
  • Lin, Yong
  • Mehta, Amit R
  • Stein, Mark N
  • Dipaola, Robert S
  • Lu-Yao, Grace L
subjects:
  • Medicine
ispartof: Archives of Internal Medicine, 26 July 2010, Vol.170(14)
description: BACKGROUND Despite controversy over the benefit of prostate-specific antigen (PSA) screening, little is known about risk profiles and treatment patterns in men diagnosed as having prostate cancer who have a PSA value less than or equal to 4.0 ng/mL. METHODS We used data from the Surveillance, Epidemiology, and End Results system to describe patient characteristics and treatment patterns in the cases of 123 934 men with newly diagnosed prostate cancer from 2004 to 2006. Age-standardized treatment rates were calculated in 5-year age strata. Logistic regression was used to quantify the odds ratios (ORs) of men with low- and high-risk disease and the use of radical prostatectomy (RP) or radiation therapy (RT). RESULTS Men with a PSA level of 4.0 ng/mL or lower represent 14% of incident prostate cancer cases. Fifty-four percent of men diagnosed as having prostate cancer and PSA levels lower than 4.0 ng/mL harbor low-risk disease (stage, ≤T2a, PSA level, ≤10 ng/mL, and Gleason score,...
language: eng
source:
identifier: ISSN: 0003-9926 ; E-ISSN: 1538-3679 ; DOI: 10.1001/archinternmed.2010.221
fulltext: no_fulltext
issn:
  • 0003-9926
  • 00039926
  • 1538-3679
  • 15383679
url: Link


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descriptionBACKGROUND Despite controversy over the benefit of prostate-specific antigen (PSA) screening, little is known about risk profiles and treatment patterns in men diagnosed as having prostate cancer who have a PSA value less than or equal to 4.0 ng/mL. METHODS We used data from the Surveillance, Epidemiology, and End Results system to describe patient characteristics and treatment patterns in the cases of 123 934 men with newly diagnosed prostate cancer from 2004 to 2006. Age-standardized treatment rates were calculated in 5-year age strata. Logistic regression was used to quantify the odds ratios (ORs) of men with low- and high-risk disease and the use of radical prostatectomy (RP) or radiation therapy (RT). RESULTS Men with a PSA level of 4.0 ng/mL or lower represent 14% of incident prostate cancer cases. Fifty-four percent of men diagnosed as having prostate cancer and PSA levels lower than 4.0 ng/mL harbor low-risk disease (stage, ≤T2a, PSA level, ≤10 ng/mL, and Gleason score,...
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titleRisk Profiles and Treatment Patterns Among Men Diagnosed as Having Prostate Cancer and a Prostate-Specific Antigen Level Below 4.0 ng/mL
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BACKGROUND Despite controversy over the benefit of prostate-specific antigen (PSA) screening, little is known about risk profiles and treatment patterns in men diagnosed as having prostate cancer who have a PSA value less than or equal to 4.0 ng/mL. METHODS We used data from the Surveillance, Epidemiology, and End Results system to describe patient characteristics and treatment patterns in the cases of 123 934 men with newly diagnosed prostate cancer from 2004 to 2006. Age-standardized treatment rates were calculated in 5-year age strata. Logistic regression was used to quantify the odds ratios (ORs) of men with low- and high-risk disease and the use of radical prostatectomy (RP) or radiation therapy (RT). RESULTS Men with a PSA level of 4.0 ng/mL or lower represent 14% of incident prostate cancer cases. Fifty-four percent of men diagnosed as having prostate cancer and PSA levels lower than 4.0 ng/mL harbor low-risk disease (stage, ≤T2a, PSA level, ≤10 ng/mL, and Gleason score,...

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BACKGROUND Despite controversy over the benefit of prostate-specific antigen (PSA) screening, little is known about risk profiles and treatment patterns in men diagnosed as having prostate cancer who have a PSA value less than or equal to 4.0 ng/mL. METHODS We used data from the Surveillance, Epidemiology, and End Results system to describe patient characteristics and treatment patterns in the cases of 123 934 men with newly diagnosed prostate cancer from 2004 to 2006. Age-standardized treatment rates were calculated in 5-year age strata. Logistic regression was used to quantify the odds ratios (ORs) of men with low- and high-risk disease and the use of radical prostatectomy (RP) or radiation therapy (RT). RESULTS Men with a PSA level of 4.0 ng/mL or lower represent 14% of incident prostate cancer cases. Fifty-four percent of men diagnosed as having prostate cancer and PSA levels lower than 4.0 ng/mL harbor low-risk disease (stage, ≤T2a, PSA level, ≤10 ng/mL, and Gleason score,...

pubAmerican Medical Association
doi10.1001/archinternmed.2010.221
lad01Archives of Internal Medicine
pages1256-12561
date2010-07-26