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Child and Adolescent Health From 1990 to 2015: Findings From the Global Burden of Diseases, Injuries, and Risk Factors 2015 Study

IMPORTANCE: Comprehensive and timely monitoring of disease burden in all age groups, including children and adolescents, is essential for improving population health. OBJECTIVE: To quantify and describe levels and trends of mortality and nonfatal health outcomes among children and adolescents from 1... Full description

Journal Title: JAMA Pediatrics 01 June 2017, Vol.171(6), pp.573-592
Main Author: Kassebaum, Nicholas
Other Authors: Kyu, Hmwe Hmwe , Zoeckler, Leo , Olsen, Helen Elizabeth , Thomas, Katie , Pinho, Christine , Bhutta, Zulfiqar A , Dandona, Lalit , Ferrari, Alize , Ghiwot, Tsegaye Tewelde , Hay, Simon I , Kinfu, Yohannes , Liang, Xiaofeng , Lopez, Alan , Malta, Deborah Carvalho , Mokdad, Ali H , Naghavi, Mohsen , Patton, George C , Salomon, Joshua , Sartorius, Benn , Topor-Madry, Roman , Vollset, Stein Emil , Werdecker, Andrea , Whiteford, Harvey A , Abate, Kalkidan Hasen , Abbas, Kaja , Damtew, Solomon Abrha , Ahmed, Muktar Beshir , Akseer, Nadia , Al-Raddadi, Rajaa , Alemayohu, Mulubirhan Assefa , Altirkawi, Khalid , Abajobir, Amanuel Alemu , Amare, Azmeraw T , Antonio, Carl A. T , Arnlov, Johan , Artaman, Al , Asayesh, Hamid , Avokpaho, Euripide Frinel G. Arthur , Awasthi, Ashish , Ayala Quintanilla, Beatriz Paulina , Bacha, Umar , Betsu, Balem Demtsu , Barac, Aleksandra , Bärnighausen, Till Winfried , Baye, Estifanos , Bedi, Neeraj , Bensenor, Isabela M , Berhane, Adugnaw , Bernabe, Eduardo , Bernal, Oscar Alberto , Beyene, Addisu Shunu , Biadgilign, Sibhatu , Bikbov, Boris , Boyce, Cheryl Anne , Brazinova, Alexandra , Hailu, Gessessew Bugssa , Carter, Austin , Castañeda-Orjuela, Carlos A , Catalá-López, Ferrán , Charlson, Fiona J , Chitheer, Abdulaal A , Choi, Jee-Young Jasmine , Ciobanu, Liliana G , Crump, John , Dandona, Rakhi , Dellavalle, Robert P , Deribew, Amare , Deveber, Gabrielle , Dicker, Daniel , Ding, Eric L , Dubey, Manisha , Endries, Amanuel Yesuf , Erskine, Holly E , Faraon, Emerito Jose Aquino , Faro, Andre , Farzadfar, Farshad , Fernandes, Joao C , Fijabi, Daniel Obadare , Fitzmaurice, Christina , Fleming, Thomas D , Flor, Luisa Sorio , Foreman, Kyle J , Franklin, Richard C , Fraser, Maya S , Frostad, Joseph J , Fullman, Nancy , Gebregergs, Gebremedhin Berhe , Gebru, Alemseged Aregay , Geleijnse, Johanna M , Gibney, Katherine B , Gidey Yihdego, Mahari , Ginawi, Ibrahim Abdelmageem Mohamed , Gishu, Melkamu Dedefo , Gizachew, Tessema Assefa , Glaser, Elizabeth , Gold, Audra L , Goldberg, Ellen , Gona, Philimon , Goto, Atsushi , Gugnani, Harish Chander , Jiang, Guohong , Gupta, Rajeev , Tesfay, Fisaha Haile , Hankey, Graeme J , Havmoeller, Rasmus , Hijar, Martha , Horino, Masako , Hosgood, H. Dean , Hu, Guoqing , Jacobsen, Kathryn H , Jakovljevic, Mihajlo B , Jayaraman, Sudha P , Jha, Vivekanand , Jibat, Tariku , Johnson, Catherine O , Jonas, Jost , Kasaeian, Amir , Kawakami, Norito , Keiyoro, Peter N , Khalil, Ibrahim , Khang, Young-Ho , Khubchandani, Jagdish , Ahmad Kiadaliri, Aliasghar A , Kieling, Christian , Kim, Daniel , Kissoon, Niranjan , Knibbs, Luke D , Koyanagi, Ai , Krohn, Kristopher J , Kuate Defo, Barthelemy , Kucuk Bicer, Burcu , Kulikoff, Rachel , Kumar, G. Anil , Lal, Dharmesh Kumar , Lam, Hilton Y , Larson, Heidi J , Larsson, Anders , Laryea, Dennis Odai , Leung, Janni , Lim, Stephen S , Lo, Loon-Tzian , Lo, Warren D , Looker, Katharine J , Lotufo, Paulo A , Magdy Abd El Razek, Hassan , Malekzadeh, Reza , Markos Shifti, Desalegn , Mazidi, Mohsen , Meaney, Peter A , Meles, Kidanu Gebremariam , Memiah, Peter , Mendoza, Walter , Abera Mengistie, Mubarek , Mengistu, Gebremichael Welday , Mensah, George A , Miller, Ted R , Mock, Charles , Mohammadi, Alireza , Mohammed, Shafiu , Monasta, Lorenzo , Mueller, Ulrich , Nagata, Chie , Naheed, Aliya , Nguyen, Grant , Nguyen, Quyen Le , Nsoesie, Elaine , Oh, In-Hwan , Okoro, Anselm , Olusanya, Jacob Olusegun , Olusanya, Bolajoko O , Ortiz, Alberto , Paudel, Deepak , Pereira, David M , Perico, Norberto , Petzold, Max , Phillips, Michael Robert , Polanczyk, Guilherme V , Pourmalek, Farshad , Qorbani, Mostafa , Rafay, Anwar , Rahimi-Movaghar, Vafa , Rahman, Mahfuzar , Rai, Rajesh Kumar , Ram, Usha , Rankin, Zane , Remuzzi, Giuseppe , Renzaho, Andre M. N , Roba, Hirbo Shore , Rojas-Rueda, David , Ronfani, Luca , Sagar, Rajesh , Sanabria, Juan Ramon , Kedir Mohammed, Muktar Sano , Santos, Itamar S , Satpathy, Maheswar , Sawhney, Monika , Schöttker, Ben , Schwebel, David C , Scott, James G , Sepanlou, Sadaf G , Shaheen, Amira , Shaikh, Masood Ali , She, June , Shiri, Rahman , Shiue, Ivy , Sigfusdottir, Inga Dora , Singh, Jasvinder , Silpakit, Naris , Smith, Alison , Sreeramareddy, Chandrashekhar , Stanaway, Jeffrey D , Stein, Dan J , Steiner, Caitlyn , Sufiyan, Muawiyyah Babale , Swaminathan, Soumya , Tabarés-Seisdedos, Rafael , Tabb, Karen M , Tadese, Fentaw , Tavakkoli, Mohammad , Taye, Bineyam , Teeple, Stephanie , Tegegne, Teketo Kassaw , Temam Shifa, Girma , Terkawi, Abdullah Sulieman , Thomas, Bernadette , Thomson, Alan J , Tobe-Gai, Ruoyan , Tonelli, Marcello , Tran, Bach Xuan , Troeger, Christopher , Ukwaja, Kingsley N , Uthman, Olalekan , Vasankari, Tommi , Venketasubramanian, Narayanaswamy , Vlassov, Vasiliy Victorovich , Weiderpass, Elisabete , Weintraub, Robert , Gebrehiwot, Solomon Weldemariam , Westerman, Ronny , Williams, Hywel C , Wolfe, Charles D. A , Woodbrook, Rachel , Yano, Yuichiro , Yonemoto, Naohiro , Yoon, Seok-Jun , Younis, Mustafa Z , Yu, Chuanhua , Zaki, Maysaa El Sayed , Zegeye, Elias Asfaw
Format: Electronic Article Electronic Article
Language: English
Subjects:
ID: ISSN: 2168-6203 ; E-ISSN: 2168-6211 ; DOI: 10.1001/jamapediatrics.2017.0250
Link: http://dx.doi.org/10.1001/jamapediatrics.2017.0250
Zum Text:
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recordid: ama2613463
title: Child and Adolescent Health From 1990 to 2015: Findings From the Global Burden of Diseases, Injuries, and Risk Factors 2015 Study
format: Article
creator:
  • Kassebaum, Nicholas
  • Kyu, Hmwe Hmwe
  • Zoeckler, Leo
  • Olsen, Helen Elizabeth
  • Thomas, Katie
  • Pinho, Christine
  • Bhutta, Zulfiqar A
  • Dandona, Lalit
  • Ferrari, Alize
  • Ghiwot, Tsegaye Tewelde
  • Hay, Simon I
  • Kinfu, Yohannes
  • Liang, Xiaofeng
  • Lopez, Alan
  • Malta, Deborah Carvalho
  • Mokdad, Ali H
  • Naghavi, Mohsen
  • Patton, George C
  • Salomon, Joshua
  • Sartorius, Benn
  • Topor-Madry, Roman
  • Vollset, Stein Emil
  • Werdecker, Andrea
  • Whiteford, Harvey A
  • Abate, Kalkidan Hasen
  • Abbas, Kaja
  • Damtew, Solomon Abrha
  • Ahmed, Muktar Beshir
  • Akseer, Nadia
  • Al-Raddadi, Rajaa
  • Alemayohu, Mulubirhan Assefa
  • Altirkawi, Khalid
  • Abajobir, Amanuel Alemu
  • Amare, Azmeraw T
  • Antonio, Carl A. T
  • Arnlov, Johan
  • Artaman, Al
  • Asayesh, Hamid
  • Avokpaho, Euripide Frinel G. Arthur
  • Awasthi, Ashish
  • Ayala Quintanilla, Beatriz Paulina
  • Bacha, Umar
  • Betsu, Balem Demtsu
  • Barac, Aleksandra
  • Bärnighausen, Till Winfried
  • Baye, Estifanos
  • Bedi, Neeraj
  • Bensenor, Isabela M
  • Berhane, Adugnaw
  • Bernabe, Eduardo
  • Bernal, Oscar Alberto
  • Beyene, Addisu Shunu
  • Biadgilign, Sibhatu
  • Bikbov, Boris
  • Boyce, Cheryl Anne
  • Brazinova, Alexandra
  • Hailu, Gessessew Bugssa
  • Carter, Austin
  • Castañeda-Orjuela, Carlos A
  • Catalá-López, Ferrán
  • Charlson, Fiona J
  • Chitheer, Abdulaal A
  • Choi, Jee-Young Jasmine
  • Ciobanu, Liliana G
  • Crump, John
  • Dandona, Rakhi
  • Dellavalle, Robert P
  • Deribew, Amare
  • Deveber, Gabrielle
  • Dicker, Daniel
  • Ding, Eric L
  • Dubey, Manisha
  • Endries, Amanuel Yesuf
  • Erskine, Holly E
  • Faraon, Emerito Jose Aquino
  • Faro, Andre
  • Farzadfar, Farshad
  • Fernandes, Joao C
  • Fijabi, Daniel Obadare
  • Fitzmaurice, Christina
  • Fleming, Thomas D
  • Flor, Luisa Sorio
  • Foreman, Kyle J
  • Franklin, Richard C
  • Fraser, Maya S
  • Frostad, Joseph J
  • Fullman, Nancy
  • Gebregergs, Gebremedhin Berhe
  • Gebru, Alemseged Aregay
  • Geleijnse, Johanna M
  • Gibney, Katherine B
  • Gidey Yihdego, Mahari
  • Ginawi, Ibrahim Abdelmageem Mohamed
  • Gishu, Melkamu Dedefo
  • Gizachew, Tessema Assefa
  • Glaser, Elizabeth
  • Gold, Audra L
  • Goldberg, Ellen
  • Gona, Philimon
  • Goto, Atsushi
  • Gugnani, Harish Chander
  • Jiang, Guohong
  • Gupta, Rajeev
  • Tesfay, Fisaha Haile
  • Hankey, Graeme J
  • Havmoeller, Rasmus
  • Hijar, Martha
  • Horino, Masako
  • Hosgood, H. Dean
  • Hu, Guoqing
  • Jacobsen, Kathryn H
  • Jakovljevic, Mihajlo B
  • Jayaraman, Sudha P
  • Jha, Vivekanand
  • Jibat, Tariku
  • Johnson, Catherine O
  • Jonas, Jost
  • Kasaeian, Amir
  • Kawakami, Norito
  • Keiyoro, Peter N
  • Khalil, Ibrahim
  • Khang, Young-Ho
  • Khubchandani, Jagdish
  • Ahmad Kiadaliri, Aliasghar A
  • Kieling, Christian
  • Kim, Daniel
  • Kissoon, Niranjan
  • Knibbs, Luke D
  • Koyanagi, Ai
  • Krohn, Kristopher J
  • Kuate Defo, Barthelemy
  • Kucuk Bicer, Burcu
  • Kulikoff, Rachel
  • Kumar, G. Anil
  • Lal, Dharmesh Kumar
  • Lam, Hilton Y
  • Larson, Heidi J
  • Larsson, Anders
  • Laryea, Dennis Odai
  • Leung, Janni
  • Lim, Stephen S
  • Lo, Loon-Tzian
  • Lo, Warren D
  • Looker, Katharine J
  • Lotufo, Paulo A
  • Magdy Abd El Razek, Hassan
  • Malekzadeh, Reza
  • Markos Shifti, Desalegn
  • Mazidi, Mohsen
  • Meaney, Peter A
  • Meles, Kidanu Gebremariam
  • Memiah, Peter
  • Mendoza, Walter
  • Abera Mengistie, Mubarek
  • Mengistu, Gebremichael Welday
  • Mensah, George A
  • Miller, Ted R
  • Mock, Charles
  • Mohammadi, Alireza
  • Mohammed, Shafiu
  • Monasta, Lorenzo
  • Mueller, Ulrich
  • Nagata, Chie
  • Naheed, Aliya
  • Nguyen, Grant
  • Nguyen, Quyen Le
  • Nsoesie, Elaine
  • Oh, In-Hwan
  • Okoro, Anselm
  • Olusanya, Jacob Olusegun
  • Olusanya, Bolajoko O
  • Ortiz, Alberto
  • Paudel, Deepak
  • Pereira, David M
  • Perico, Norberto
  • Petzold, Max
  • Phillips, Michael Robert
  • Polanczyk, Guilherme V
  • Pourmalek, Farshad
  • Qorbani, Mostafa
  • Rafay, Anwar
  • Rahimi-Movaghar, Vafa
  • Rahman, Mahfuzar
  • Rai, Rajesh Kumar
  • Ram, Usha
  • Rankin, Zane
  • Remuzzi, Giuseppe
  • Renzaho, Andre M. N
  • Roba, Hirbo Shore
  • Rojas-Rueda, David
  • Ronfani, Luca
  • Sagar, Rajesh
  • Sanabria, Juan Ramon
  • Kedir Mohammed, Muktar Sano
  • Santos, Itamar S
  • Satpathy, Maheswar
  • Sawhney, Monika
  • Schöttker, Ben
  • Schwebel, David C
  • Scott, James G
  • Sepanlou, Sadaf G
  • Shaheen, Amira
  • Shaikh, Masood Ali
  • She, June
  • Shiri, Rahman
  • Shiue, Ivy
  • Sigfusdottir, Inga Dora
  • Singh, Jasvinder
  • Silpakit, Naris
  • Smith, Alison
  • Sreeramareddy, Chandrashekhar
  • Stanaway, Jeffrey D
  • Stein, Dan J
  • Steiner, Caitlyn
  • Sufiyan, Muawiyyah Babale
  • Swaminathan, Soumya
  • Tabarés-Seisdedos, Rafael
  • Tabb, Karen M
  • Tadese, Fentaw
  • Tavakkoli, Mohammad
  • Taye, Bineyam
  • Teeple, Stephanie
  • Tegegne, Teketo Kassaw
  • Temam Shifa, Girma
  • Terkawi, Abdullah Sulieman
  • Thomas, Bernadette
  • Thomson, Alan J
  • Tobe-Gai, Ruoyan
  • Tonelli, Marcello
  • Tran, Bach Xuan
  • Troeger, Christopher
  • Ukwaja, Kingsley N
  • Uthman, Olalekan
  • Vasankari, Tommi
  • Venketasubramanian, Narayanaswamy
  • Vlassov, Vasiliy Victorovich
  • Weiderpass, Elisabete
  • Weintraub, Robert
  • Gebrehiwot, Solomon Weldemariam
  • Westerman, Ronny
  • Williams, Hywel C
  • Wolfe, Charles D. A
  • Woodbrook, Rachel
  • Yano, Yuichiro
  • Yonemoto, Naohiro
  • Yoon, Seok-Jun
  • Younis, Mustafa Z
  • Yu, Chuanhua
  • Zaki, Maysaa El Sayed
  • Zegeye, Elias Asfaw
subjects:
  • Medicine
ispartof: JAMA Pediatrics, 01 June 2017, Vol.171(6), pp.573-592
description: IMPORTANCE: Comprehensive and timely monitoring of disease burden in all age groups, including children and adolescents, is essential for improving population health. OBJECTIVE: To quantify and describe levels and trends of mortality and nonfatal health outcomes among children and adolescents from 1990 to 2015 to provide a framework for policy discussion. EVIDENCE REVIEW: Cause-specific mortality and nonfatal health outcomes were analyzed for 195 countries and territories by age group, sex, and year from 1990 to 2015 using standardized approaches for data processing and statistical modeling, with subsequent analysis of the findings to describe levels and trends across geography and time among children and adolescents 19 years or younger. A composite indicator of income, education, and fertility was developed (Socio-demographic Index [SDI]) for each geographic unit and year, which evaluates the historical association between SDI and health loss. FINDINGS: Global child and adolescent mortality decreased from 14.18 million (95% uncertainty interval [UI], 14.09 million to 14.28 million) deaths in 1990 to 7.26 million (95% UI, 7.14 million to 7.39 million) deaths in 2015, but progress has been unevenly distributed. Countries with a lower SDI had a larger proportion of mortality burden (75%) in 2015 than was the case in 1990 (61%). Most deaths in 2015 occurred in South Asia and sub-Saharan Africa. Global trends were driven by reductions in mortality owing to infectious, nutritional, and neonatal disorders, which in the aggregate led to a relative increase in the importance of noncommunicable diseases and injuries in explaining global disease burden. The absolute burden of disability in children and adolescents increased 4.3% (95% UI, 3.1%-5.6%) from 1990 to 2015, with much of the increase owing to population growth and improved survival for children and adolescents to older ages. Other than infectious conditions, many top causes of disability are associated with long-term sequelae of conditions present at birth (eg, neonatal disorders, congenital birth defects, and hemoglobinopathies) and complications of a variety of infections and nutritional deficiencies. Anemia, developmental intellectual disability, hearing loss, epilepsy, and vision loss are important contributors to childhood disability that can arise from multiple causes. Maternal and reproductive health remains a key cause of disease burden in adolescent females, especially in lower-SDI countries. In lo
language: eng
source:
identifier: ISSN: 2168-6203 ; E-ISSN: 2168-6211 ; DOI: 10.1001/jamapediatrics.2017.0250
fulltext: fulltext
issn:
  • 2168-6203
  • 21686203
  • 2168-6211
  • 21686211
url: Link


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titleChild and Adolescent Health From 1990 to 2015: Findings From the Global Burden of Diseases, Injuries, and Risk Factors 2015 Study
creatorKassebaum, Nicholas ; Kyu, Hmwe Hmwe ; Zoeckler, Leo ; Olsen, Helen Elizabeth ; Thomas, Katie ; Pinho, Christine ; Bhutta, Zulfiqar A ; Dandona, Lalit ; Ferrari, Alize ; Ghiwot, Tsegaye Tewelde ; Hay, Simon I ; Kinfu, Yohannes ; Liang, Xiaofeng ; Lopez, Alan ; Malta, Deborah Carvalho ; Mokdad, Ali H ; Naghavi, Mohsen ; Patton, George C ; Salomon, Joshua ; Sartorius, Benn ; Topor-Madry, Roman ; Vollset, Stein Emil ; Werdecker, Andrea ; Whiteford, Harvey A ; Abate, Kalkidan Hasen ; Abbas, Kaja ; Damtew, Solomon Abrha ; Ahmed, Muktar Beshir ; Akseer, Nadia ; Al-Raddadi, Rajaa ; Alemayohu, Mulubirhan Assefa ; Altirkawi, Khalid ; Abajobir, Amanuel Alemu ; Amare, Azmeraw T ; Antonio, Carl A. T ; Arnlov, Johan ; Artaman, Al ; Asayesh, Hamid ; Avokpaho, Euripide Frinel G. Arthur ; Awasthi, Ashish ; Ayala Quintanilla, Beatriz Paulina ; Bacha, Umar ; Betsu, Balem Demtsu ; Barac, Aleksandra ; Bärnighausen, Till Winfried ; Baye, Estifanos ; Bedi, Neeraj ; Bensenor, Isabela M ; Berhane, Adugnaw ; Bernabe, Eduardo ; Bernal, Oscar Alberto ; Beyene, Addisu Shunu ; Biadgilign, Sibhatu ; Bikbov, Boris ; Boyce, Cheryl Anne ; Brazinova, Alexandra ; Hailu, Gessessew Bugssa ; Carter, Austin ; Castañeda-Orjuela, Carlos A ; Catalá-López, Ferrán ; Charlson, Fiona J ; Chitheer, Abdulaal A ; Choi, Jee-Young Jasmine ; Ciobanu, Liliana G ; Crump, John ; Dandona, Rakhi ; Dellavalle, Robert P ; Deribew, Amare ; Deveber, Gabrielle ; Dicker, Daniel ; Ding, Eric L ; Dubey, Manisha ; Endries, Amanuel Yesuf ; Erskine, Holly E ; Faraon, Emerito Jose Aquino ; Faro, Andre ; Farzadfar, Farshad ; Fernandes, Joao C ; Fijabi, Daniel Obadare ; Fitzmaurice, Christina ; Fleming, Thomas D ; Flor, Luisa Sorio ; Foreman, Kyle J ; Franklin, Richard C ; Fraser, Maya S ; Frostad, Joseph J ; Fullman, Nancy ; Gebregergs, Gebremedhin Berhe ; Gebru, Alemseged Aregay ; Geleijnse, Johanna M ; Gibney, Katherine B ; Gidey Yihdego, Mahari ; Ginawi, Ibrahim Abdelmageem Mohamed ; Gishu, Melkamu Dedefo ; Gizachew, Tessema Assefa ; Glaser, Elizabeth ; Gold, Audra L ; Goldberg, Ellen ; Gona, Philimon ; Goto, Atsushi ; Gugnani, Harish Chander ; Jiang, Guohong ; Gupta, Rajeev ; Tesfay, Fisaha Haile ; Hankey, Graeme J ; Havmoeller, Rasmus ; Hijar, Martha ; Horino, Masako ; Hosgood, H. Dean ; Hu, Guoqing ; Jacobsen, Kathryn H ; Jakovljevic, Mihajlo B ; Jayaraman, Sudha P ; Jha, Vivekanand ; Jibat, Tariku ; Johnson, Catherine O ; Jonas, Jost ; Kasaeian, Amir ; Kawakami, Norito ; Keiyoro, Peter N ; Khalil, Ibrahim ; Khang, Young-Ho ; Khubchandani, Jagdish ; Ahmad Kiadaliri, Aliasghar A ; Kieling, Christian ; Kim, Daniel ; Kissoon, Niranjan ; Knibbs, Luke D ; Koyanagi, Ai ; Krohn, Kristopher J ; Kuate Defo, Barthelemy ; Kucuk Bicer, Burcu ; Kulikoff, Rachel ; Kumar, G. Anil ; Lal, Dharmesh Kumar ; Lam, Hilton Y ; Larson, Heidi J ; Larsson, Anders ; Laryea, Dennis Odai ; Leung, Janni ; Lim, Stephen S ; Lo, Loon-Tzian ; Lo, Warren D ; Looker, Katharine J ; Lotufo, Paulo A ; Magdy Abd El Razek, Hassan ; Malekzadeh, Reza ; Markos Shifti, Desalegn ; Mazidi, Mohsen ; Meaney, Peter A ; Meles, Kidanu Gebremariam ; Memiah, Peter ; Mendoza, Walter ; Abera Mengistie, Mubarek ; Mengistu, Gebremichael Welday ; Mensah, George A ; Miller, Ted R ; Mock, Charles ; Mohammadi, Alireza ; Mohammed, Shafiu ; Monasta, Lorenzo ; Mueller, Ulrich ; Nagata, Chie ; Naheed, Aliya ; Nguyen, Grant ; Nguyen, Quyen Le ; Nsoesie, Elaine ; Oh, In-Hwan ; Okoro, Anselm ; Olusanya, Jacob Olusegun ; Olusanya, Bolajoko O ; Ortiz, Alberto ; Paudel, Deepak ; Pereira, David M ; Perico, Norberto ; Petzold, Max ; Phillips, Michael Robert ; Polanczyk, Guilherme V ; Pourmalek, Farshad ; Qorbani, Mostafa ; Rafay, Anwar ; Rahimi-Movaghar, Vafa ; Rahman, Mahfuzar ; Rai, Rajesh Kumar ; Ram, Usha ; Rankin, Zane ; Remuzzi, Giuseppe ; Renzaho, Andre M. N ; Roba, Hirbo Shore ; Rojas-Rueda, David ; Ronfani, Luca ; Sagar, Rajesh ; Sanabria, Juan Ramon ; Kedir Mohammed, Muktar Sano ; Santos, Itamar S ; Satpathy, Maheswar ; Sawhney, Monika ; Schöttker, Ben ; Schwebel, David C ; Scott, James G ; Sepanlou, Sadaf G ; Shaheen, Amira ; Shaikh, Masood Ali ; She, June ; Shiri, Rahman ; Shiue, Ivy ; Sigfusdottir, Inga Dora ; Singh, Jasvinder ; Silpakit, Naris ; Smith, Alison ; Sreeramareddy, Chandrashekhar ; Stanaway, Jeffrey D ; Stein, Dan J ; Steiner, Caitlyn ; Sufiyan, Muawiyyah Babale ; Swaminathan, Soumya ; Tabarés-Seisdedos, Rafael ; Tabb, Karen M ; Tadese, Fentaw ; Tavakkoli, Mohammad ; Taye, Bineyam ; Teeple, Stephanie ; Tegegne, Teketo Kassaw ; Temam Shifa, Girma ; Terkawi, Abdullah Sulieman ; Thomas, Bernadette ; Thomson, Alan J ; Tobe-Gai, Ruoyan ; Tonelli, Marcello ; Tran, Bach Xuan ; Troeger, Christopher ; Ukwaja, Kingsley N ; Uthman, Olalekan ; Vasankari, Tommi ; Venketasubramanian, Narayanaswamy ; Vlassov, Vasiliy Victorovich ; Weiderpass, Elisabete ; Weintraub, Robert ; Gebrehiwot, Solomon Weldemariam ; Westerman, Ronny ; Williams, Hywel C ; Wolfe, Charles D. A ; Woodbrook, Rachel ; Yano, Yuichiro ; Yonemoto, Naohiro ; Yoon, Seok-Jun ; Younis, Mustafa Z ; Yu, Chuanhua ; Zaki, Maysaa El Sayed ; Zegeye, Elias Asfaw
ispartofJAMA Pediatrics, 01 June 2017, Vol.171(6), pp.573-592
identifier
subjectMedicine
descriptionIMPORTANCE: Comprehensive and timely monitoring of disease burden in all age groups, including children and adolescents, is essential for improving population health. OBJECTIVE: To quantify and describe levels and trends of mortality and nonfatal health outcomes among children and adolescents from 1990 to 2015 to provide a framework for policy discussion. EVIDENCE REVIEW: Cause-specific mortality and nonfatal health outcomes were analyzed for 195 countries and territories by age group, sex, and year from 1990 to 2015 using standardized approaches for data processing and statistical modeling, with subsequent analysis of the findings to describe levels and trends across geography and time among children and adolescents 19 years or younger. A composite indicator of income, education, and fertility was developed (Socio-demographic Index [SDI]) for each geographic unit and year, which evaluates the historical association between SDI and health loss. FINDINGS: Global child and adolescent mortality decreased from 14.18 million (95% uncertainty interval [UI], 14.09 million to 14.28 million) deaths in 1990 to 7.26 million (95% UI, 7.14 million to 7.39 million) deaths in 2015, but progress has been unevenly distributed. Countries with a lower SDI had a larger proportion of mortality burden (75%) in 2015 than was the case in 1990 (61%). Most deaths in 2015 occurred in South Asia and sub-Saharan Africa. Global trends were driven by reductions in mortality owing to infectious, nutritional, and neonatal disorders, which in the aggregate led to a relative increase in the importance of noncommunicable diseases and injuries in explaining global disease burden. The absolute burden of disability in children and adolescents increased 4.3% (95% UI, 3.1%-5.6%) from 1990 to 2015, with much of the increase owing to population growth and improved survival for children and adolescents to older ages. Other than infectious conditions, many top causes of disability are associated with long-term sequelae of conditions present at birth (eg, neonatal disorders, congenital birth defects, and hemoglobinopathies) and complications of a variety of infections and nutritional deficiencies. Anemia, developmental intellectual disability, hearing loss, epilepsy, and vision loss are important contributors to childhood disability that can arise from multiple causes. Maternal and reproductive health remains a key cause of disease burden in adolescent females, especially in lower-SDI countries. In low-SDI countries, mortality is the primary driver of health loss for children and adolescents, whereas disability predominates in higher-SDI locations; the specific pattern of epidemiological transition varies across diseases and injuries. CONCLUSIONS AND RELEVANCE: Consistent international attention and investment have led to sustained improvements in causes of health loss among children and adolescents in many countries, although progress has been uneven. The persistence of infectious diseases in some countries, coupled with ongoing epidemiologic transition to injuries and noncommunicable diseases, require all countries to carefully evaluate and implement appropriate strategies to maximize the health of their children and adolescents and for the international community to carefully consider which elements of child and adolescent health should be monitored.
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0Kassebaum, Nicholas
1Kyu, Hmwe Hmwe
2Zoeckler, Leo
3Olsen, Helen Elizabeth
4Thomas, Katie
5Pinho, Christine
6Bhutta, Zulfiqar A
7Dandona, Lalit
8Ferrari, Alize
9Ghiwot, Tsegaye Tewelde
10Hay, Simon I
11Kinfu, Yohannes
12Liang, Xiaofeng
13Lopez, Alan
14Malta, Deborah Carvalho
15Mokdad, Ali H
16Naghavi, Mohsen
17Patton, George C
18Salomon, Joshua
19Sartorius, Benn
20Topor-Madry, Roman
21Vollset, Stein Emil
22Werdecker, Andrea
23Whiteford, Harvey A
24Abate, Kalkidan Hasen
25Abbas, Kaja
26Damtew, Solomon Abrha
27Ahmed, Muktar Beshir
28Akseer, Nadia
29Al-Raddadi, Rajaa
30Alemayohu, Mulubirhan Assefa
31Altirkawi, Khalid
32Abajobir, Amanuel Alemu
33Amare, Azmeraw T
34Antonio, Carl A. T
35Arnlov, Johan
36Artaman, Al
37Asayesh, Hamid
38Avokpaho, Euripide Frinel G. Arthur
39Awasthi, Ashish
40Ayala Quintanilla, Beatriz Paulina
41Bacha, Umar
42Betsu, Balem Demtsu
43Barac, Aleksandra
44Bärnighausen, Till Winfried
45Baye, Estifanos
46Bedi, Neeraj
47Bensenor, Isabela M
48Berhane, Adugnaw
49Bernabe, Eduardo
50Bernal, Oscar Alberto
51Beyene, Addisu Shunu
52Biadgilign, Sibhatu
53Bikbov, Boris
54Boyce, Cheryl Anne
55Brazinova, Alexandra
56Hailu, Gessessew Bugssa
57Carter, Austin
58Castañeda-Orjuela, Carlos A
59Catalá-López, Ferrán
60Charlson, Fiona J
61Chitheer, Abdulaal A
62Choi, Jee-Young Jasmine
63Ciobanu, Liliana G
64Crump, John
65Dandona, Rakhi
66Dellavalle, Robert P
67Deribew, Amare
68Deveber, Gabrielle
69Dicker, Daniel
70Ding, Eric L
71Dubey, Manisha
72Endries, Amanuel Yesuf
73Erskine, Holly E
74Faraon, Emerito Jose Aquino
75Faro, Andre
76Farzadfar, Farshad
77Fernandes, Joao C
78Fijabi, Daniel Obadare
79Fitzmaurice, Christina
80Fleming, Thomas D
81Flor, Luisa Sorio
82Foreman, Kyle J
83Franklin, Richard C
84Fraser, Maya S
85Frostad, Joseph J
86Fullman, Nancy
87Gebregergs, Gebremedhin Berhe
88Gebru, Alemseged Aregay
89Geleijnse, Johanna M
90Gibney, Katherine B
91Gidey Yihdego, Mahari
92Ginawi, Ibrahim Abdelmageem Mohamed
93Gishu, Melkamu Dedefo
94Gizachew, Tessema Assefa
95Glaser, Elizabeth
96Gold, Audra L
97Goldberg, Ellen
98Gona, Philimon
99Goto, Atsushi
100...
titleChild and Adolescent Health From 1990 to 2015: Findings From the Global Burden of Diseases, Injuries, and Risk Factors 2015 Study
description

IMPORTANCE: Comprehensive and timely monitoring of disease burden in all age groups, including children and adolescents, is essential for improving population health. OBJECTIVE: To quantify and describe levels and trends of mortality and nonfatal health outcomes among children and adolescents from 1990 to 2015 to provide a framework for policy discussion. EVIDENCE REVIEW: Cause-specific mortality and nonfatal health outcomes were analyzed for 195 countries and territories by age group, sex, and year from 1990 to 2015 using standardized approaches for data processing and statistical modeling, with subsequent analysis of the findings to describe levels and trends across geography and time among children and adolescents 19 years or younger. A composite indicator of income, education, and fertility was developed (Socio-demographic Index [SDI]) for each geographic unit and year, which evaluates the historical association between SDI and health loss. FINDINGS: Global child and adolescent mortality decreased from 14.18 million (95% uncertainty interval [UI], 14.09 million to 14.28 million) deaths in 1990 to 7.26 million (95% UI, 7.14 million to 7.39 million) deaths in 2015, but progress has been unevenly distributed. Countries with a lower SDI had a larger proportion of mortality burden (75%) in 2015 than was the case in 1990 (61%). Most deaths in 2015 occurred in South Asia and sub-Saharan Africa. Global trends were driven by reductions in mortality owing to infectious, nutritional, and neonatal disorders, which in the aggregate led to a relative increase in the importance of noncommunicable diseases and injuries in explaining global disease burden. The absolute burden of disability in children and adolescents increased 4.3% (95% UI, 3.1%-5.6%) from 1990 to 2015, with much of the increase owing to population growth and improved survival for children and adolescents to older ages. Other than infectious conditions, many top causes of disability are associated with long-term sequelae of conditions present at birth (eg, neonatal disorders, congenital birth defects, and hemoglobinopathies) and complications of a variety of infections and nutritional deficiencies. Anemia, developmental intellectual disability, hearing loss, epilepsy, and vision loss are important contributors to childhood disability that can arise from multiple causes. Maternal and reproductive health remains a key cause of disease burden in adolescent females, especially in lower-SDI countries. In low-SDI countries, mortality is the primary driver of health loss for children and adolescents, whereas disability predominates in higher-SDI locations; the specific pattern of epidemiological transition varies across diseases and injuries. CONCLUSIONS AND RELEVANCE: Consistent international attention and investment have led to sustained improvements in causes of health loss among children and adolescents in many countries, although progress has been uneven. The persistence of infectious diseases in some countries, coupled with ongoing epidemiologic transition to injuries and noncommunicable diseases, require all countries to carefully evaluate and implement appropriate strategies to maximize the health of their children and adolescents and for the international community to carefully consider which elements of child and adolescent health should be monitored.

subjectMedicine
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1American Medical Association
210.1001/jamapediatrics.2017.0250
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4American Medical Association Journals
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lsr40JAMA Pediatrics, 01 June 2017, Vol.171 (6), pp.573-592
doi10.1001/jamapediatrics.2017.0250
citationpf 573 pt 592 vol 171 issue 6
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titleChild and Adolescent Health From 1990 to 2015: Findings From the Global Burden of Diseases, Injuries, and Risk Factors 2015 Study
authorKassebaum, Nicholas ; Kyu, Hmwe Hmwe ; Zoeckler, Leo ; Olsen, Helen Elizabeth ; Thomas, Katie ; Pinho, Christine ; Bhutta, Zulfiqar A ; Dandona, Lalit ; Ferrari, Alize ; Ghiwot, Tsegaye Tewelde ; Hay, Simon I ; Kinfu, Yohannes ; Liang, Xiaofeng ; Lopez, Alan ; Malta, Deborah Carvalho ; Mokdad, Ali H ; Naghavi, Mohsen ; Patton, George C ; Salomon, Joshua ; Sartorius, Benn ; Topor-Madry, Roman ; Vollset, Stein Emil ; Werdecker, Andrea ; Whiteford, Harvey A ; Abate, Kalkidan Hasen ; Abbas, Kaja ; Damtew, Solomon Abrha ; Ahmed, Muktar Beshir ; Akseer, Nadia ; Al-Raddadi, Rajaa ; Alemayohu, Mulubirhan Assefa ; Altirkawi, Khalid ; Abajobir, Amanuel Alemu ; Amare, Azmeraw T ; Antonio, Carl A. T ; Arnlov, Johan ; Artaman, Al ; Asayesh, Hamid ; Avokpaho, Euripide Frinel G. Arthur ; Awasthi, Ashish ; Ayala Quintanilla, Beatriz Paulina ; Bacha, Umar ; Betsu, Balem Demtsu ; Barac, Aleksandra ; Bärnighausen, Till Winfried ; Baye, Estifanos ; Bedi, Neeraj ; Bensenor, Isabela M ; Berhane, Adugnaw ; Bernabe, Eduardo ; Bernal, Oscar Alberto ; Beyene, Addisu Shunu ; Biadgilign, Sibhatu ; Bikbov, Boris ; Boyce, Cheryl Anne ; Brazinova, Alexandra ; Hailu, Gessessew Bugssa ; Carter, Austin ; Castañeda-Orjuela, Carlos A ; Catalá-López, Ferrán ; Charlson, Fiona J ; Chitheer, Abdulaal A ; Choi, Jee-Young Jasmine ; Ciobanu, Liliana G ; Crump, John ; Dandona, Rakhi ; Dellavalle, Robert P ; Deribew, Amare ; Deveber, Gabrielle ; Dicker, Daniel ; Ding, Eric L ; Dubey, Manisha ; Endries, Amanuel Yesuf ; Erskine, Holly E ; Faraon, Emerito Jose Aquino ; Faro, Andre ; Farzadfar, Farshad ; Fernandes, Joao C ; Fijabi, Daniel Obadare ; Fitzmaurice, Christina ; Fleming, Thomas D ; Flor, Luisa Sorio ; Foreman, Kyle J ; Franklin, Richard C ; Fraser, Maya S ; Frostad, Joseph J ; Fullman, Nancy ; Gebregergs, Gebremedhin Berhe ; Gebru, Alemseged Aregay ; Geleijnse, Johanna M ; Gibney, Katherine B ; Gidey Yihdego, Mahari ; Ginawi, Ibrahim Abdelmageem Mohamed ; Gishu, Melkamu Dedefo ; Gizachew, Tessema Assefa ; Glaser, Elizabeth ; Gold, Audra L ; Goldberg, Ellen ; Gona, Philimon ; Goto, Atsushi ; Gugnani, Harish Chander ; Jiang, Guohong ; Gupta, Rajeev ; Tesfay, Fisaha Haile ; Hankey, Graeme J ; Havmoeller, Rasmus ; Hijar, Martha ; Horino, Masako ; Hosgood, H. Dean ; Hu, Guoqing ; Jacobsen, Kathryn H ; Jakovljevic, Mihajlo B ; Jayaraman, Sudha P ; Jha, Vivekanand ; Jibat, Tariku ; Johnson, Catherine O ; Jonas, Jost ; Kasaeian, Amir ; Kawakami, Norito ; Keiyoro, Peter N ; Khalil, Ibrahim ; Khang, Young-Ho ; Khubchandani, Jagdish ; Ahmad Kiadaliri, Aliasghar A ; Kieling, Christian ; Kim, Daniel ; Kissoon, Niranjan ; Knibbs, Luke D ; Koyanagi, Ai ; Krohn, Kristopher J ; Kuate Defo, Barthelemy ; Kucuk Bicer, Burcu ; Kulikoff, Rachel ; Kumar, G. Anil ; Lal, Dharmesh Kumar ; Lam, Hilton Y ; Larson, Heidi J ; Larsson, Anders ; Laryea, Dennis Odai ; Leung, Janni ; Lim, Stephen S ; Lo, Loon-Tzian ; Lo, Warren D ; Looker, Katharine J ; Lotufo, Paulo A ; Magdy Abd El Razek, Hassan ; Malekzadeh, Reza ; Markos Shifti, Desalegn ; Mazidi, Mohsen ; Meaney, Peter A ; Meles, Kidanu Gebremariam ; Memiah, Peter ; Mendoza, Walter ; Abera Mengistie, Mubarek ; Mengistu, Gebremichael Welday ; Mensah, George A ; Miller, Ted R ; Mock, Charles ; Mohammadi, Alireza ; Mohammed, Shafiu ; Monasta, Lorenzo ; Mueller, Ulrich ; Nagata, Chie ; Naheed, Aliya ; Nguyen, Grant ; Nguyen, Quyen Le ; Nsoesie, Elaine ; Oh, In-Hwan ; Okoro, Anselm ; Olusanya, Jacob Olusegun ; Olusanya, Bolajoko O ; Ortiz, Alberto ; Paudel, Deepak ; Pereira, David M ; Perico, Norberto ; Petzold, Max ; Phillips, Michael Robert ; Polanczyk, Guilherme V ; Pourmalek, Farshad ; Qorbani, Mostafa ; Rafay, Anwar ; Rahimi-Movaghar, Vafa ; Rahman, Mahfuzar ; Rai, Rajesh Kumar ; Ram, Usha ; Rankin, Zane ; Remuzzi, Giuseppe ; Renzaho, Andre M. N ; Roba, Hirbo Shore ; Rojas-Rueda, David ; Ronfani, Luca ; Sagar, Rajesh ; Sanabria, Juan Ramon ; Kedir Mohammed, Muktar Sano ; Santos, Itamar S ; Satpathy, Maheswar ; Sawhney, Monika ; Schöttker, Ben ; Schwebel, David C ; Scott, James G ; Sepanlou, Sadaf G ; Shaheen, Amira ; Shaikh, Masood Ali ; She, June ; Shiri, Rahman ; Shiue, Ivy ; Sigfusdottir, Inga Dora ; Singh, Jasvinder ; Silpakit, Naris ; Smith, Alison ; Sreeramareddy, Chandrashekhar ; Stanaway, Jeffrey D ; Stein, Dan J ; Steiner, Caitlyn ; Sufiyan, Muawiyyah Babale ; Swaminathan, Soumya ; Tabarés-Seisdedos, Rafael ; Tabb, Karen M ; Tadese, Fentaw ; Tavakkoli, Mohammad ; Taye, Bineyam ; Teeple, Stephanie ; Tegegne, Teketo Kassaw ; Temam Shifa, Girma ; Terkawi, Abdullah Sulieman ; Thomas, Bernadette ; Thomson, Alan J ; Tobe-Gai, Ruoyan ; Tonelli, Marcello ; Tran, Bach Xuan ; Troeger, Christopher ; Ukwaja, Kingsley N ; Uthman, Olalekan ; Vasankari, Tommi ; Venketasubramanian, Narayanaswamy ; Vlassov, Vasiliy Victorovich ; Weiderpass, Elisabete ; Weintraub, Robert ; Gebrehiwot, Solomon Weldemariam ; Westerman, Ronny ; Williams, Hywel C ; Wolfe, Charles D. A ; Woodbrook, Rachel ; Yano, Yuichiro ; Yonemoto, Naohiro ; Yoon, Seok-Jun ; Younis, Mustafa Z ; Yu, Chuanhua ; Zaki, Maysaa El Sayed ; Zegeye, Elias Asfaw
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1American Medical Association Journals
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creatorcontrib
0Kassebaum, Nicholas
1Kyu, Hmwe Hmwe
2Zoeckler, Leo
3Olsen, Helen Elizabeth
4Thomas, Katie
5Pinho, Christine
6Bhutta, Zulfiqar A
7Dandona, Lalit
8Ferrari, Alize
9Ghiwot, Tsegaye Tewelde
10Hay, Simon I
11Kinfu, Yohannes
12Liang, Xiaofeng
13Lopez, Alan
14Malta, Deborah Carvalho
15Mokdad, Ali H
16Naghavi, Mohsen
17Patton, George C
18Salomon, Joshua
19Sartorius, Benn
20Topor-Madry, Roman
21Vollset, Stein Emil
22Werdecker, Andrea
23Whiteford, Harvey A
24Abate, Kalkidan Hasen
25Abbas, Kaja
26Damtew, Solomon Abrha
27Ahmed, Muktar Beshir
28Akseer, Nadia
29Al-Raddadi, Rajaa
30Alemayohu, Mulubirhan Assefa
31Altirkawi, Khalid
32Abajobir, Amanuel Alemu
33Amare, Azmeraw T
34Antonio, Carl A. T
35Arnlov, Johan
36Artaman, Al
37Asayesh, Hamid
38Avokpaho, Euripide Frinel G. Arthur
39Awasthi, Ashish
40Ayala Quintanilla, Beatriz Paulina
41Bacha, Umar
42Betsu, Balem Demtsu
43Barac, Aleksandra
44Bärnighausen, Till Winfried
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47Bensenor, Isabela M
48Berhane, Adugnaw
49Bernabe, Eduardo
50Bernal, Oscar Alberto
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55Brazinova, Alexandra
56Hailu, Gessessew Bugssa
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60Charlson, Fiona J
61Chitheer, Abdulaal A
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66Dellavalle, Robert P
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72Endries, Amanuel Yesuf
73Erskine, Holly E
74Faraon, Emerito Jose Aquino
75Faro, Andre
76Farzadfar, Farshad
77Fernandes, Joao C
78Fijabi, Daniel Obadare
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92Ginawi, Ibrahim Abdelmageem Mohamed
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94Gizachew, Tessema Assefa
95Glaser, Elizabeth
96Gold, Audra L
97Goldberg, Ellen
98Gona, Philimon
99Goto, Atsushi
100...
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7Dandona, Lalit
8Ferrari, Alize
9Ghiwot, Tsegaye Tewelde
10Hay, Simon I
11Kinfu, Yohannes
12Liang, Xiaofeng
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15Mokdad, Ali H
16Naghavi, Mohsen
17Patton, George C
18Salomon, Joshua
19Sartorius, Benn
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22Werdecker, Andrea
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24Abate, Kalkidan Hasen
25Abbas, Kaja
26Damtew, Solomon Abrha
27Ahmed, Muktar Beshir
28Akseer, Nadia
29Al-Raddadi, Rajaa
30Alemayohu, Mulubirhan Assefa
31Altirkawi, Khalid
32Abajobir, Amanuel Alemu
33Amare, Azmeraw T
34Antonio, Carl A. T
35Arnlov, Johan
36Artaman, Al
37Asayesh, Hamid
38Avokpaho, Euripide Frinel G. Arthur
39Awasthi, Ashish
40Ayala Quintanilla, Beatriz Paulina
41Bacha, Umar
42Betsu, Balem Demtsu
43Barac, Aleksandra
44Bärnighausen, Till Winfried
45Baye, Estifanos
46Bedi, Neeraj
47Bensenor, Isabela M
48Berhane, Adugnaw
49Bernabe, Eduardo
50Bernal, Oscar Alberto
51Beyene, Addisu Shunu
52Biadgilign, Sibhatu
53Bikbov, Boris
54Boyce, Cheryl Anne
55Brazinova, Alexandra
56Hailu, Gessessew Bugssa
57Carter, Austin
58Castañeda-Orjuela, Carlos A
59Catalá-López, Ferrán
60Charlson, Fiona J
61Chitheer, Abdulaal A
62Choi, Jee-Young Jasmine
63Ciobanu, Liliana G
64Crump, John
65Dandona, Rakhi
66Dellavalle, Robert P
67Deribew, Amare
68Deveber, Gabrielle
69Dicker, Daniel
70Ding, Eric L
71Dubey, Manisha
72Endries, Amanuel Yesuf
73Erskine, Holly E
74Faraon, Emerito Jose Aquino
75Faro, Andre
76Farzadfar, Farshad
77Fernandes, Joao C
78Fijabi, Daniel Obadare
79Fitzmaurice, Christina
80Fleming, Thomas D
81Flor, Luisa Sorio
82Foreman, Kyle J
83Franklin, Richard C
84Fraser, Maya S
85Frostad, Joseph J
86Fullman, Nancy
87Gebregergs, Gebremedhin Berhe
88Gebru, Alemseged Aregay
89Geleijnse, Johanna M
90Gibney, Katherine B
91Gidey Yihdego, Mahari
92Ginawi, Ibrahim Abdelmageem Mohamed
93Gishu, Melkamu Dedefo
94Gizachew, Tessema Assefa
95Glaser, Elizabeth
96Gold, Audra L
97Goldberg, Ellen
98Gona, Philimon
99Goto, Atsushi
100...
atitleChild and Adolescent Health From 1990 to 2015: Findings From the Global Burden of Diseases, Injuries, and Risk Factors 2015 Study
jtitleJAMA Pediatrics
risdate20170601
volume171
issue6
spage573
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pages573-592
issn2168-6203
eissn2168-6211
formatjournal
genrearticle
ristypeJOUR
abstract

IMPORTANCE: Comprehensive and timely monitoring of disease burden in all age groups, including children and adolescents, is essential for improving population health. OBJECTIVE: To quantify and describe levels and trends of mortality and nonfatal health outcomes among children and adolescents from 1990 to 2015 to provide a framework for policy discussion. EVIDENCE REVIEW: Cause-specific mortality and nonfatal health outcomes were analyzed for 195 countries and territories by age group, sex, and year from 1990 to 2015 using standardized approaches for data processing and statistical modeling, with subsequent analysis of the findings to describe levels and trends across geography and time among children and adolescents 19 years or younger. A composite indicator of income, education, and fertility was developed (Socio-demographic Index [SDI]) for each geographic unit and year, which evaluates the historical association between SDI and health loss. FINDINGS: Global child and adolescent mortality decreased from 14.18 million (95% uncertainty interval [UI], 14.09 million to 14.28 million) deaths in 1990 to 7.26 million (95% UI, 7.14 million to 7.39 million) deaths in 2015, but progress has been unevenly distributed. Countries with a lower SDI had a larger proportion of mortality burden (75%) in 2015 than was the case in 1990 (61%). Most deaths in 2015 occurred in South Asia and sub-Saharan Africa. Global trends were driven by reductions in mortality owing to infectious, nutritional, and neonatal disorders, which in the aggregate led to a relative increase in the importance of noncommunicable diseases and injuries in explaining global disease burden. The absolute burden of disability in children and adolescents increased 4.3% (95% UI, 3.1%-5.6%) from 1990 to 2015, with much of the increase owing to population growth and improved survival for children and adolescents to older ages. Other than infectious conditions, many top causes of disability are associated with long-term sequelae of conditions present at birth (eg, neonatal disorders, congenital birth defects, and hemoglobinopathies) and complications of a variety of infections and nutritional deficiencies. Anemia, developmental intellectual disability, hearing loss, epilepsy, and vision loss are important contributors to childhood disability that can arise from multiple causes. Maternal and reproductive health remains a key cause of disease burden in adolescent females, especially in lower-SDI countries. In low-SDI countries, mortality is the primary driver of health loss for children and adolescents, whereas disability predominates in higher-SDI locations; the specific pattern of epidemiological transition varies across diseases and injuries. CONCLUSIONS AND RELEVANCE: Consistent international attention and investment have led to sustained improvements in causes of health loss among children and adolescents in many countries, although progress has been uneven. The persistence of infectious diseases in some countries, coupled with ongoing epidemiologic transition to injuries and noncommunicable diseases, require all countries to carefully evaluate and implement appropriate strategies to maximize the health of their children and adolescents and for the international community to carefully consider which elements of child and adolescent health should be monitored.

pubAmerican Medical Association
doi10.1001/jamapediatrics.2017.0250
date2017-06-01