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Frequent nut consumption and risk of coronary heart disease in women: prospective cohort study

To examine the relation between nut consumption and risk of coronary heart disease in a cohort of women from the Nurses' Health Study.

Journal Title: BMJ 14 November 1998, Vol.317(7169), p.1341
Main Author: Hu, Frank B
Other Authors: Stampfer, Meir J , Manson, Joann E , Rimm, Eric B , Colditz, Graham A , Rosner, Bernard A , Speizer, Frank E , Hennekens, Charles H , Willett, Walter C
Format: Electronic Article Electronic Article
Language: English
Subjects:
Publisher: British Medical Journal Publishing Group
ID: ISSN: 0959-8138 ; E-ISSN: 1468-5833 ; DOI: 10.1136/bmj.317.7169.1341 ; PMID: 9812929
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recordid: bmj_journals10.1136/bmj.317.7169.1341
title: Frequent nut consumption and risk of coronary heart disease in women: prospective cohort study
format: Article
creator:
  • Hu, Frank B
  • Stampfer, Meir J
  • Manson, Joann E
  • Rimm, Eric B
  • Colditz, Graham A
  • Rosner, Bernard A
  • Speizer, Frank E
  • Hennekens, Charles H
  • Willett, Walter C
subjects:
  • Smoking and Tobacco
  • Epidemiologic Studies
  • Drugs: Cardiovascular System
  • Stroke
  • Diet
  • Ischaemic Heart Disease
  • Health Education
  • Health Promotion
  • Smoking
ispartof: BMJ, 14 November 1998, Vol.317(7169), p.1341
description: To examine the relation between nut consumption and risk of coronary heart disease in a cohort of women from the Nurses' Health Study.
language: eng
source:
identifier: ISSN: 0959-8138 ; E-ISSN: 1468-5833 ; DOI: 10.1136/bmj.317.7169.1341 ; PMID: 9812929
fulltext: fulltext
issn:
  • 09598138
  • 14685833
  • 0959-8138
  • 1468-5833
url: Link


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8Willett, Walter C
titleFrequent nut consumption and risk of coronary heart disease in women: prospective cohort study
descriptionTo examine the relation between nut consumption and risk of coronary heart disease in a cohort of women from the Nurses' Health Study.
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titleFrequent nut consumption and risk of coronary heart disease in women: prospective cohort study
authorHu, Frank B ; Stampfer, Meir J ; Manson, Joann E ; Rimm, Eric B ; Colditz, Graham A ; Rosner, Bernard A ; Speizer, Frank E ; Hennekens, Charles H ; Willett, Walter C
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0Hu, Frank B
1Stampfer, Meir J
2Manson, Joann E
3Rimm, Eric B
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atitleFrequent nut consumption and risk of coronary heart disease in women: prospective cohort study
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0To examine the relation between nut consumption and risk of coronary heart disease in a cohort of women from the Nurses' Health Study.
1Prospective cohort study.
2Nurses' Health Study.
386 016 women from 34 to 59 years of age without previously diagnosed coronary heart disease, stroke, or cancer at baseline in 1980.
4Major coronary heart disease including non-fatal myocardial infarction and fatal coronary heart disease.
51255 major coronary disease events (861 cases of non-fatal myocardial infarction and 394 cases of fatal coronary heart disease) occurred during 14 years of follow up. After adjusting for age, smoking, and other known risk factors for coronary heart disease, women who ate more than five units of nuts (one unit equivalent to 1 oz of nuts) a week (frequent consumption) had a significantly lower risk of total coronary heart disease (relative risk 0.65, 95% confidence interval 0.47 to 0.89, P for trend=0.0009) than women who never ate nuts or who ate less than one unit a month (rare consumption). The magnitude of risk reduction was similar for both fatal coronary heart disease (0.61, 0.35 to 1.05, P for trend=0.007) and non-fatal myocardial infarction (0.68, 0.47 to 1.00, P for trend=0.04). Further adjustment for intakes of dietary fats, fibre, vegetables, and fruits did not alter these results. The inverse association persisted in subgroups stratified by levels of smoking, use of alcohol, use of multivitamin and vitamin E supplements, body mass index, exercise, and intake of vegetables or fruits.
6Frequent nut consumption was associated with a reduced risk of both fatal coronary heart disease and non-fatal myocardial infarction. These data, and those from other epidemiological and clinical studies, support a role for nuts in reducing the risk of coronary heart disease.
pubBritish Medical Journal Publishing Group
doi10.1136/bmj.317.7169.1341
urlhttp://bmj.com/content/317/7169/1341.full.pdf
pmid9812929
pages1341-1345
date1998-11-14