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MicroRNA-223 ameliorates alcoholic liver injury by inhibiting the IL-6–p47 phox –oxidative stress pathway in neutrophils

Chronic-plus-binge ethanol feeding activates neutrophils and exacerbates liver injury in mice. This study investigates how recent excessive drinking affects peripheral neutrophils and liver injury in alcoholics, and how miR-223, one of the most abundant microRNAs (miRNAs) in neutrophils, modulates n... Full description

Journal Title: Gut 27 April 2017, Vol.66(4), p.705
Main Author: Li, Man
Other Authors: He, Yong , Zhou, Zhou , Ramirez, Teresa , Gao, Yueqiu , Gao, Yanhang , Ross, Ruth A , Cao, Haixia , Cai, Yan , Xu, Mingjiang , Feng, Dechun , Zhang, Ping , Liangpunsakul, Suthat , Gao, Bin
Format: Electronic Article Electronic Article
Language: English
Subjects:
Publisher: BMJ Publishing Group Ltd and British Society of Gastroenterology
ID: ISSN: 0017-5749 ; E-ISSN: 1468-3288 ; DOI: 10.1136/gutjnl-2016-311861 ; PMID: 27679493
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recordid: bmj_journals10.1136/gutjnl-2016-311861
title: MicroRNA-223 ameliorates alcoholic liver injury by inhibiting the IL-6–p47 phox –oxidative stress pathway in neutrophils
format: Article
creator:
  • Li, Man
  • He, Yong
  • Zhou, Zhou
  • Ramirez, Teresa
  • Gao, Yueqiu
  • Gao, Yanhang
  • Ross, Ruth A
  • Cao, Haixia
  • Cai, Yan
  • Xu, Mingjiang
  • Feng, Dechun
  • Zhang, Ping
  • Liangpunsakul, Suthat
  • Gao, Bin
subjects:
  • Inflammation
  • Ethanol
  • Cytokines
  • Fatty Liver
  • Leukocytes
ispartof: Gut, 27 April 2017, Vol.66(4), p.705
description: Chronic-plus-binge ethanol feeding activates neutrophils and exacerbates liver injury in mice. This study investigates how recent excessive drinking affects peripheral neutrophils and liver injury in alcoholics, and how miR-223, one of the most abundant microRNAs (miRNAs) in neutrophils, modulates neutrophil function and liver injury in ethanol-fed mice.
language: eng
source:
identifier: ISSN: 0017-5749 ; E-ISSN: 1468-3288 ; DOI: 10.1136/gutjnl-2016-311861 ; PMID: 27679493
fulltext: no_fulltext
issn:
  • 00175749
  • 14683288
  • 0017-5749
  • 1468-3288
url: Link


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titleMicroRNA-223 ameliorates alcoholic liver injury by inhibiting the IL-6–p47 phox –oxidative stress pathway in neutrophils
creatorLi, Man ; He, Yong ; Zhou, Zhou ; Ramirez, Teresa ; Gao, Yueqiu ; Gao, Yanhang ; Ross, Ruth A ; Cao, Haixia ; Cai, Yan ; Xu, Mingjiang ; Feng, Dechun ; Zhang, Ping ; Liangpunsakul, Suthat ; Gao, Bin
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descriptionChronic-plus-binge ethanol feeding activates neutrophils and exacerbates liver injury in mice. This study investigates how recent excessive drinking affects peripheral neutrophils and liver injury in alcoholics, and how miR-223, one of the most abundant microRNAs (miRNAs) in neutrophils, modulates neutrophil function and liver injury in ethanol-fed mice.
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titleMicroRNA-223 ameliorates alcoholic liver injury by inhibiting the IL-6–p47 phox –oxidative stress pathway in neutrophils
descriptionChronic-plus-binge ethanol feeding activates neutrophils and exacerbates liver injury in mice. This study investigates how recent excessive drinking affects peripheral neutrophils and liver injury in alcoholics, and how miR-223, one of the most abundant microRNAs (miRNAs) in neutrophils, modulates neutrophil function and liver injury in ethanol-fed mice.
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abstractChronic-plus-binge ethanol feeding activates neutrophils and exacerbates liver injury in mice. This study investigates how recent excessive drinking affects peripheral neutrophils and liver injury in alcoholics, and how miR-223, one of the most abundant microRNAs (miRNAs) in neutrophils, modulates neutrophil function and liver injury in ethanol-fed mice.
pubBMJ Publishing Group Ltd and British Society of Gastroenterology
doi10.1136/gutjnl-2016-311861
urlhttp://gut.bmj.com/content/66/4/705.full.pdf
pmid27679493
pages705-715
date2017-04-27