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Emergent cardiovascular risk factors in the very elderly

An appreciable amount of evidence generated in the recent decades has changed the incidence and mortality of cardiovascular diseases dramatically. This advance has resulted in increased survival and, consequently, in a large new generation of very elderly individuals. In parallel, the aging of the p... Full description

Journal Title: Expert review of cardiovascular therapy 2012-10-01, Vol.10 (10), p.1221-1225
Main Author: Moura, Filipe A
Other Authors: Freitas, Wladimir M , Sposito, Andrei C
Format: Electronic Article Electronic Article
Language: English
Subjects:
Quelle: Alma/SFX Local Collection
Publisher: London: Informa Healthcare
ID: ISSN: 1477-9072
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recordid: cdi_proquest_journals_1220659337
title: Emergent cardiovascular risk factors in the very elderly
format: Article
creator:
  • Moura, Filipe A
  • Freitas, Wladimir M
  • Sposito, Andrei C
subjects:
  • Aged
  • aging
  • atherogenesis
  • Cardiovascular diseases
  • Development and progression
  • Health aspects
  • Heart attack
  • Prognosis
  • Risk factors
  • very elderly
ispartof: Expert review of cardiovascular therapy, 2012-10-01, Vol.10 (10), p.1221-1225
description: An appreciable amount of evidence generated in the recent decades has changed the incidence and mortality of cardiovascular diseases dramatically. This advance has resulted in increased survival and, consequently, in a large new generation of very elderly individuals. In parallel, the aging of the population brought out a puzzle and a challenge for the next millennium. Despite the role of selective survival in attenuating the expression and impact of traditional risk factors, today's elderly still has a gradual increase in unstable plaque formation and, by this way, the incidence of acute cardiovascular events. Recent studies have indicated aging-related emergence of new potential modulators of atherogenesis such as cellular senescence, immunosenescence, the syndrome of frailty, sarcopenia and sirtuins. This review will focus on the most recent and relevant evidence regarding the impact of these new players on atherogenicity in the elderly.
language: eng
source: Alma/SFX Local Collection
identifier: ISSN: 1477-9072
fulltext: fulltext
issn:
  • 1477-9072
  • 1744-8344
url: Link


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descriptionAn appreciable amount of evidence generated in the recent decades has changed the incidence and mortality of cardiovascular diseases dramatically. This advance has resulted in increased survival and, consequently, in a large new generation of very elderly individuals. In parallel, the aging of the population brought out a puzzle and a challenge for the next millennium. Despite the role of selective survival in attenuating the expression and impact of traditional risk factors, today's elderly still has a gradual increase in unstable plaque formation and, by this way, the incidence of acute cardiovascular events. Recent studies have indicated aging-related emergence of new potential modulators of atherogenesis such as cellular senescence, immunosenescence, the syndrome of frailty, sarcopenia and sirtuins. This review will focus on the most recent and relevant evidence regarding the impact of these new players on atherogenicity in the elderly.
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subjectAged ; aging ; atherogenesis ; Cardiovascular diseases ; Development and progression ; Health aspects ; Heart attack ; Prognosis ; Risk factors ; very elderly
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abstractAn appreciable amount of evidence generated in the recent decades has changed the incidence and mortality of cardiovascular diseases dramatically. This advance has resulted in increased survival and, consequently, in a large new generation of very elderly individuals. In parallel, the aging of the population brought out a puzzle and a challenge for the next millennium. Despite the role of selective survival in attenuating the expression and impact of traditional risk factors, today's elderly still has a gradual increase in unstable plaque formation and, by this way, the incidence of acute cardiovascular events. Recent studies have indicated aging-related emergence of new potential modulators of atherogenesis such as cellular senescence, immunosenescence, the syndrome of frailty, sarcopenia and sirtuins. This review will focus on the most recent and relevant evidence regarding the impact of these new players on atherogenicity in the elderly.
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