schliessen

Filtern

 

Bibliotheken

Swimming Training Prevents Alterations in Acetylcholinesterase and Butyrylcholinesterase Activities in Hypertensive Rats

BACKGROUND Cholinergic enzyme activities are altered in hypertension, reflecting a low-grade inflammation. Regular physical exercise exerts anti-inflammatory effects and has been described as a coadjutant in the treatment of hypertension. In this study, we investigated the effect of 6 weeks of swimm... Full description

Journal Title: American journal of hypertension 2014, Vol.27 (4), p.522-529
Main Author: Cardoso, Andréia Machado
Other Authors: Abdalla, Fátima Husein , Bagatini, Margarete Dulce , Martins, Caroline Curry , da Silva Fiorin, Fernando , Baldissarelli, Jucimara , Costa, Pauline , de Mello, Fábio Fernandes , Fiorenza, Amanda Maino , da Silva Serres, Jonas Daci , Gonçalves, Jamile Fabbrin , Chaves, Heloísa , Royes, Luiz Fernando Freire , Belló-Klein, Adriane , Morsch, Vera Maria , Schetinger, Maria Rosa Chitolina
Format: Electronic Article Electronic Article
Language: English
Subjects:
Quelle: Alma/SFX Local Collection
Publisher: US: Oxford University Press
ID: ISSN: 0895-7061
Link: https://www.ncbi.nlm.nih.gov/pubmed/23479073
Zum Text:
SendSend as email Add to Book BagAdd to Book Bag
Staff View
recordid: cdi_proquest_journals_1611607893
title: Swimming Training Prevents Alterations in Acetylcholinesterase and Butyrylcholinesterase Activities in Hypertensive Rats
format: Article
creator:
  • Cardoso, Andréia Machado
  • Abdalla, Fátima Husein
  • Bagatini, Margarete Dulce
  • Martins, Caroline Curry
  • da Silva Fiorin, Fernando
  • Baldissarelli, Jucimara
  • Costa, Pauline
  • de Mello, Fábio Fernandes
  • Fiorenza, Amanda Maino
  • da Silva Serres, Jonas Daci
  • Gonçalves, Jamile Fabbrin
  • Chaves, Heloísa
  • Royes, Luiz Fernando Freire
  • Belló-Klein, Adriane
  • Morsch, Vera Maria
  • Schetinger, Maria Rosa Chitolina
subjects:
  • Acetylcholinesterase - blood
  • Animals
  • Blood Pressure
  • Butyrylcholinesterase - blood
  • Care and treatment
  • Cholinesterases
  • Development and progression
  • Enzymes
  • Exercise
  • Health aspects
  • Hypertension
  • Hypertension - blood
  • Hypertension - chemically induced
  • Hypertension - physiopathology
  • Hypertension - therapy
  • Inflammation - prevention & control
  • Lymphocytes - enzymology
  • Male
  • Medical research
  • Medicine, Experimental
  • NG-Nitroarginine Methyl Ester
  • Physical Conditioning, Animal
  • Physiological aspects
  • Rats
  • Rats, Wistar
  • Rodents
  • Swimming
ispartof: American journal of hypertension, 2014, Vol.27 (4), p.522-529
description: BACKGROUND Cholinergic enzyme activities are altered in hypertension, reflecting a low-grade inflammation. Regular physical exercise exerts anti-inflammatory effects and has been described as a coadjutant in the treatment of hypertension. In this study, we investigated the effect of 6 weeks of swimming training on cholinergic enzyme activities (acetylcholinesterase and butyrylcholinesterase) in Nω-Nitro-L-arginine methyl ester hydrochloride (L-NAME)-induced hypertensive rats. METHODS The rats were divided into 4 groups: control (n = 10), exercise (n = 10), L-NAME (n = 10), and exercise L-NAME (n = 10). The animals were trained 5 times per week in an adapted swimming system for 60 minutes with a gradual increase of the workload up to 5% of animal's body weight. Enzyme activities were measured spectrophotometrically in lymphocytes, whole blood, and serum. RESULTS A significant rise in acetylcholinesterase activity was observed in lymphocytes and whole blood as well as in serum butyrylcholinesterase activity in the L-NAME group when compared with the other groups (P < 0.05), and the increase in cholinesterase activities was positively correlated with the rise in blood pressure (r = 0.5721, r = 0.6121, and r = 0.5811, respectively). Swimming training was efficient in preventing these alterations in the exercise L-NAME group, which displayed values similar to those of the control group. Exercise training demonstrated a significant hypotensive effect in hypertensive rats. CONCLUSIONS Exercise training was shown to prevent increased cholinesterase related to inflammatory processes in hypertensive rats, providing a new insight about protective exercise mechanisms to avoid hypertension-related inflammation.
language: eng
source: Alma/SFX Local Collection
identifier: ISSN: 0895-7061
fulltext: fulltext
issn:
  • 0895-7061
  • 1879-1905
url: Link


@attributes
NO1
SEARCH_ENGINEprimo_central_multiple_fe
SEARCH_ENGINE_TYPEPrimo Central Search Engine
RANK2.4694579
LOCALfalse
PrimoNMBib
record
control
sourceidgale_opena
recordidTN_cdi_proquest_journals_1611607893
sourceformatXML
sourcesystemPC
galeidA399819812
oup_id10.1093/ajh/hpt030
sourcerecordidA399819812
originalsourceidFETCH-LOGICAL-1499t-71f62e86badd830cd09daec4b11b39a7a8db3413f941576d2258fcd3eb690873
addsrcrecordideNp9UdFu0zAUjRCIlcELH4AiIV6QstmxG9uP3QQMNAkEfbdu7JvVVeoE2yn073GXsgdAyJZ85XvO8bk-RfGSkgtKFLuE7eZyMybCyKNiQaVQFVVk-bhYEKmWlSANPSuexbglhPCmoU-Ls5pxoYhgi-Lntx9ut3P-rlwHcP5YfAm4R59iueoTBkhu8LF0vlwZTIfebIbeeYzHVsQSvC2vpnQIf3VWJrm9Sw7vyTeHEUNCH90ey6-Q4vPiSQd9xBen87xYv3-3vr6pbj9_-Hi9uq0oVypVgnZNjbJpwVrJiLFEWUDDW0pbpkCAtC3jlHWK06VobF0vZWcsw7ZRRAp2XnyaZYcRPbiAegxuB-GgB3DaekzaQgLjEmoUHUDLCNS2tVwalJzX0NRAueCtgiz2ehYbw_B9ypPq7TAFn-1r2lDaECEVy6iLGXUHPWrnuyEFMHlZ3DkzeOxcvl8xpSTNu86EtzPBhCHGgN2DR0r0MWGdE9Zzwhn86uRhandoH6C_I80A8odaHu4-xWzD9f_WfHP6pGn839u_ADpHwoo
sourcetypeOpen Access Repository
isCDItrue
recordtypearticle
pqid1611607893
display
typearticle
titleSwimming Training Prevents Alterations in Acetylcholinesterase and Butyrylcholinesterase Activities in Hypertensive Rats
sourceAlma/SFX Local Collection
creatorCardoso, Andréia Machado ; Abdalla, Fátima Husein ; Bagatini, Margarete Dulce ; Martins, Caroline Curry ; da Silva Fiorin, Fernando ; Baldissarelli, Jucimara ; Costa, Pauline ; de Mello, Fábio Fernandes ; Fiorenza, Amanda Maino ; da Silva Serres, Jonas Daci ; Gonçalves, Jamile Fabbrin ; Chaves, Heloísa ; Royes, Luiz Fernando Freire ; Belló-Klein, Adriane ; Morsch, Vera Maria ; Schetinger, Maria Rosa Chitolina
creatorcontribCardoso, Andréia Machado ; Abdalla, Fátima Husein ; Bagatini, Margarete Dulce ; Martins, Caroline Curry ; da Silva Fiorin, Fernando ; Baldissarelli, Jucimara ; Costa, Pauline ; de Mello, Fábio Fernandes ; Fiorenza, Amanda Maino ; da Silva Serres, Jonas Daci ; Gonçalves, Jamile Fabbrin ; Chaves, Heloísa ; Royes, Luiz Fernando Freire ; Belló-Klein, Adriane ; Morsch, Vera Maria ; Schetinger, Maria Rosa Chitolina
descriptionBACKGROUND Cholinergic enzyme activities are altered in hypertension, reflecting a low-grade inflammation. Regular physical exercise exerts anti-inflammatory effects and has been described as a coadjutant in the treatment of hypertension. In this study, we investigated the effect of 6 weeks of swimming training on cholinergic enzyme activities (acetylcholinesterase and butyrylcholinesterase) in Nω-Nitro-L-arginine methyl ester hydrochloride (L-NAME)-induced hypertensive rats. METHODS The rats were divided into 4 groups: control (n = 10), exercise (n = 10), L-NAME (n = 10), and exercise L-NAME (n = 10). The animals were trained 5 times per week in an adapted swimming system for 60 minutes with a gradual increase of the workload up to 5% of animal's body weight. Enzyme activities were measured spectrophotometrically in lymphocytes, whole blood, and serum. RESULTS A significant rise in acetylcholinesterase activity was observed in lymphocytes and whole blood as well as in serum butyrylcholinesterase activity in the L-NAME group when compared with the other groups (P < 0.05), and the increase in cholinesterase activities was positively correlated with the rise in blood pressure (r = 0.5721, r = 0.6121, and r = 0.5811, respectively). Swimming training was efficient in preventing these alterations in the exercise L-NAME group, which displayed values similar to those of the control group. Exercise training demonstrated a significant hypotensive effect in hypertensive rats. CONCLUSIONS Exercise training was shown to prevent increased cholinesterase related to inflammatory processes in hypertensive rats, providing a new insight about protective exercise mechanisms to avoid hypertension-related inflammation.
identifier
0ISSN: 0895-7061
1EISSN: 1879-1905
2DOI: 10.1093/ajh/hpt030
3PMID: 23479073
4CODEN: AJHYE6
languageeng
publisherUS: Oxford University Press
subjectAcetylcholinesterase - blood ; Animals ; Blood Pressure ; Butyrylcholinesterase - blood ; Care and treatment ; Cholinesterases ; Development and progression ; Enzymes ; Exercise ; Health aspects ; Hypertension ; Hypertension - blood ; Hypertension - chemically induced ; Hypertension - physiopathology ; Hypertension - therapy ; Inflammation - prevention & control ; Lymphocytes - enzymology ; Male ; Medical research ; Medicine, Experimental ; NG-Nitroarginine Methyl Ester ; Physical Conditioning, Animal ; Physiological aspects ; Rats ; Rats, Wistar ; Rodents ; Swimming
ispartofAmerican journal of hypertension, 2014, Vol.27 (4), p.522-529
rightsAmerican Journal of Hypertension, Ltd 2013. All rights reserved. For Permissions, please email: journals.permissions@oup.com 2013
lds50peer_reviewed
oafree_for_read
citedbyFETCH-LOGICAL-1499t-71f62e86badd830cd09daec4b11b39a7a8db3413f941576d2258fcd3eb690873
citesFETCH-LOGICAL-1499t-71f62e86badd830cd09daec4b11b39a7a8db3413f941576d2258fcd3eb690873
links
openurl$$Topenurl_article
openurlfulltext$$Topenurlfull_article
thumbnail$$Usyndetics_thumb_exl
backlink$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23479073$$D View this record in MEDLINE/PubMed
search
creatorcontrib
0Cardoso, Andréia Machado
1Abdalla, Fátima Husein
2Bagatini, Margarete Dulce
3Martins, Caroline Curry
4da Silva Fiorin, Fernando
5Baldissarelli, Jucimara
6Costa, Pauline
7de Mello, Fábio Fernandes
8Fiorenza, Amanda Maino
9da Silva Serres, Jonas Daci
10Gonçalves, Jamile Fabbrin
11Chaves, Heloísa
12Royes, Luiz Fernando Freire
13Belló-Klein, Adriane
14Morsch, Vera Maria
15Schetinger, Maria Rosa Chitolina
title
0Swimming Training Prevents Alterations in Acetylcholinesterase and Butyrylcholinesterase Activities in Hypertensive Rats
1American journal of hypertension
addtitle
0AJHYPE
1Am J Hypertens
descriptionBACKGROUND Cholinergic enzyme activities are altered in hypertension, reflecting a low-grade inflammation. Regular physical exercise exerts anti-inflammatory effects and has been described as a coadjutant in the treatment of hypertension. In this study, we investigated the effect of 6 weeks of swimming training on cholinergic enzyme activities (acetylcholinesterase and butyrylcholinesterase) in Nω-Nitro-L-arginine methyl ester hydrochloride (L-NAME)-induced hypertensive rats. METHODS The rats were divided into 4 groups: control (n = 10), exercise (n = 10), L-NAME (n = 10), and exercise L-NAME (n = 10). The animals were trained 5 times per week in an adapted swimming system for 60 minutes with a gradual increase of the workload up to 5% of animal's body weight. Enzyme activities were measured spectrophotometrically in lymphocytes, whole blood, and serum. RESULTS A significant rise in acetylcholinesterase activity was observed in lymphocytes and whole blood as well as in serum butyrylcholinesterase activity in the L-NAME group when compared with the other groups (P < 0.05), and the increase in cholinesterase activities was positively correlated with the rise in blood pressure (r = 0.5721, r = 0.6121, and r = 0.5811, respectively). Swimming training was efficient in preventing these alterations in the exercise L-NAME group, which displayed values similar to those of the control group. Exercise training demonstrated a significant hypotensive effect in hypertensive rats. CONCLUSIONS Exercise training was shown to prevent increased cholinesterase related to inflammatory processes in hypertensive rats, providing a new insight about protective exercise mechanisms to avoid hypertension-related inflammation.
subject
0Acetylcholinesterase - blood
1Animals
2Blood Pressure
3Butyrylcholinesterase - blood
4Care and treatment
5Cholinesterases
6Development and progression
7Enzymes
8Exercise
9Health aspects
10Hypertension
11Hypertension - blood
12Hypertension - chemically induced
13Hypertension - physiopathology
14Hypertension - therapy
15Inflammation - prevention & control
16Lymphocytes - enzymology
17Male
18Medical research
19Medicine, Experimental
20NG-Nitroarginine Methyl Ester
21Physical Conditioning, Animal
22Physiological aspects
23Rats
24Rats, Wistar
25Rodents
26Swimming
issn
00895-7061
11879-1905
fulltexttrue
rsrctypearticle
creationdate2014
recordtypearticle
recordideNp9UdFu0zAUjRCIlcELH4AiIV6QstmxG9uP3QQMNAkEfbdu7JvVVeoE2yn073GXsgdAyJZ85XvO8bk-RfGSkgtKFLuE7eZyMybCyKNiQaVQFVVk-bhYEKmWlSANPSuexbglhPCmoU-Ls5pxoYhgi-Lntx9ut3P-rlwHcP5YfAm4R59iueoTBkhu8LF0vlwZTIfebIbeeYzHVsQSvC2vpnQIf3VWJrm9Sw7vyTeHEUNCH90ey6-Q4vPiSQd9xBen87xYv3-3vr6pbj9_-Hi9uq0oVypVgnZNjbJpwVrJiLFEWUDDW0pbpkCAtC3jlHWK06VobF0vZWcsw7ZRRAp2XnyaZYcRPbiAegxuB-GgB3DaekzaQgLjEmoUHUDLCNS2tVwalJzX0NRAueCtgiz2ehYbw_B9ypPq7TAFn-1r2lDaECEVy6iLGXUHPWrnuyEFMHlZ3DkzeOxcvl8xpSTNu86EtzPBhCHGgN2DR0r0MWGdE9Zzwhn86uRhandoH6C_I80A8odaHu4-xWzD9f_WfHP6pGn839u_ADpHwoo
startdate201404
enddate201404
creator
0Cardoso, Andréia Machado
1Abdalla, Fátima Husein
2Bagatini, Margarete Dulce
3Martins, Caroline Curry
4da Silva Fiorin, Fernando
5Baldissarelli, Jucimara
6Costa, Pauline
7de Mello, Fábio Fernandes
8Fiorenza, Amanda Maino
9da Silva Serres, Jonas Daci
10Gonçalves, Jamile Fabbrin
11Chaves, Heloísa
12Royes, Luiz Fernando Freire
13Belló-Klein, Adriane
14Morsch, Vera Maria
15Schetinger, Maria Rosa Chitolina
general
0Oxford University Press
1Oxford University Press (OUP)
scope
0CGR
1CUY
2CVF
3ECM
4EIF
5NPM
6AAYXX
7CITATION
8BSHEE
93V.
107X7
117XB
1288E
138FI
148FJ
158FK
16ABUWG
17BENPR
18FYUFA
19GHDGH
20K9.
21M0S
22M1P
23PQEST
24PQQKQ
25PQUKI
26PRINS
27CLFQK
sort
creationdate201404
titleSwimming Training Prevents Alterations in Acetylcholinesterase and Butyrylcholinesterase Activities in Hypertensive Rats
authorCardoso, Andréia Machado ; Abdalla, Fátima Husein ; Bagatini, Margarete Dulce ; Martins, Caroline Curry ; da Silva Fiorin, Fernando ; Baldissarelli, Jucimara ; Costa, Pauline ; de Mello, Fábio Fernandes ; Fiorenza, Amanda Maino ; da Silva Serres, Jonas Daci ; Gonçalves, Jamile Fabbrin ; Chaves, Heloísa ; Royes, Luiz Fernando Freire ; Belló-Klein, Adriane ; Morsch, Vera Maria ; Schetinger, Maria Rosa Chitolina
facets
frbrtype5
frbrgroupidcdi_FETCH-LOGICAL-1499t-71f62e86badd830cd09daec4b11b39a7a8db3413f941576d2258fcd3eb690873
rsrctypearticles
prefilterarticles
languageeng
creationdate2014
topic
0Acetylcholinesterase - blood
1Animals
2Blood Pressure
3Butyrylcholinesterase - blood
4Care and treatment
5Cholinesterases
6Development and progression
7Enzymes
8Exercise
9Health aspects
10Hypertension
11Hypertension - blood
12Hypertension - chemically induced
13Hypertension - physiopathology
14Hypertension - therapy
15Inflammation - prevention & control
16Lymphocytes - enzymology
17Male
18Medical research
19Medicine, Experimental
20NG-Nitroarginine Methyl Ester
21Physical Conditioning, Animal
22Physiological aspects
23Rats
24Rats, Wistar
25Rodents
26Swimming
toplevel
0peer_reviewed
1online_resources
creatorcontrib
0Cardoso, Andréia Machado
1Abdalla, Fátima Husein
2Bagatini, Margarete Dulce
3Martins, Caroline Curry
4da Silva Fiorin, Fernando
5Baldissarelli, Jucimara
6Costa, Pauline
7de Mello, Fábio Fernandes
8Fiorenza, Amanda Maino
9da Silva Serres, Jonas Daci
10Gonçalves, Jamile Fabbrin
11Chaves, Heloísa
12Royes, Luiz Fernando Freire
13Belló-Klein, Adriane
14Morsch, Vera Maria
15Schetinger, Maria Rosa Chitolina
collection
0Medline
1MEDLINE
2MEDLINE (Ovid)
3MEDLINE
4MEDLINE
5PubMed
6CrossRef
7Academic OneFile (A&I only)
8ProQuest Central (Corporate)
9Health & Medical Collection
10ProQuest Central (purchase pre-March 2016)
11Medical Database (Alumni Edition)
12Hospital Premium Collection
13Hospital Premium Collection (Alumni Edition)
14ProQuest Central (Alumni) (purchase pre-March 2016)
15ProQuest Central (Alumni Edition)
16ProQuest Central
17Health Research Premium Collection
18Health Research Premium Collection (Alumni)
19ProQuest Health & Medical Complete (Alumni)
20Health & Medical Collection (Alumni Edition)
21Medical Database
22ProQuest One Academic Eastern Edition
23ProQuest One Academic
24ProQuest One Academic UKI Edition
25ProQuest Central China
26OpenAIRE
jtitleAmerican journal of hypertension
delivery
delcategoryRemote Search Resource
fulltextfulltext
addata
au
0Cardoso, Andréia Machado
1Abdalla, Fátima Husein
2Bagatini, Margarete Dulce
3Martins, Caroline Curry
4da Silva Fiorin, Fernando
5Baldissarelli, Jucimara
6Costa, Pauline
7de Mello, Fábio Fernandes
8Fiorenza, Amanda Maino
9da Silva Serres, Jonas Daci
10Gonçalves, Jamile Fabbrin
11Chaves, Heloísa
12Royes, Luiz Fernando Freire
13Belló-Klein, Adriane
14Morsch, Vera Maria
15Schetinger, Maria Rosa Chitolina
formatjournal
genrearticle
ristypeJOUR
atitleSwimming Training Prevents Alterations in Acetylcholinesterase and Butyrylcholinesterase Activities in Hypertensive Rats
jtitleAmerican journal of hypertension
stitleAJHYPE
addtitleAm J Hypertens
date2014-04
risdate2014
volume27
issue4
spage522
epage529
pages522-529
issn0895-7061
eissn1879-1905
codenAJHYE6
abstractBACKGROUND Cholinergic enzyme activities are altered in hypertension, reflecting a low-grade inflammation. Regular physical exercise exerts anti-inflammatory effects and has been described as a coadjutant in the treatment of hypertension. In this study, we investigated the effect of 6 weeks of swimming training on cholinergic enzyme activities (acetylcholinesterase and butyrylcholinesterase) in Nω-Nitro-L-arginine methyl ester hydrochloride (L-NAME)-induced hypertensive rats. METHODS The rats were divided into 4 groups: control (n = 10), exercise (n = 10), L-NAME (n = 10), and exercise L-NAME (n = 10). The animals were trained 5 times per week in an adapted swimming system for 60 minutes with a gradual increase of the workload up to 5% of animal's body weight. Enzyme activities were measured spectrophotometrically in lymphocytes, whole blood, and serum. RESULTS A significant rise in acetylcholinesterase activity was observed in lymphocytes and whole blood as well as in serum butyrylcholinesterase activity in the L-NAME group when compared with the other groups (P < 0.05), and the increase in cholinesterase activities was positively correlated with the rise in blood pressure (r = 0.5721, r = 0.6121, and r = 0.5811, respectively). Swimming training was efficient in preventing these alterations in the exercise L-NAME group, which displayed values similar to those of the control group. Exercise training demonstrated a significant hypotensive effect in hypertensive rats. CONCLUSIONS Exercise training was shown to prevent increased cholinesterase related to inflammatory processes in hypertensive rats, providing a new insight about protective exercise mechanisms to avoid hypertension-related inflammation.
copUS
pubOxford University Press
pmid23479073
doi10.1093/ajh/hpt030
oafree_for_read