schliessen

Filtern

 

Bibliotheken

Tobacco dependence is associated with increased risk for multi-morbid clustering of posttraumatic stress disorder, depressive disorder, and pain among post-9/11 deployed veterans

Rationale Tobacco use is highly prevalent among individuals with posttraumatic stress disorder (PTSD), depressive disorders, and pain. Research has revealed pairwise relationships among these conditions but has not examined more complex relationships that may influence symptom severity, chronicity,... Full description

Journal Title: Psychopharmacology 2019-01-07, Vol.236 (6), p.1729-1739
Main Author: Fonda, Jennifer R
Other Authors: Gregor, Kristin L , Fortier, Catherine B , Scioli-Salter, Erica R , McGlinchey, Regina E , Rasmusson, Ann
Format: Electronic Article Electronic Article
Language: English
Subjects:
Publisher: Berlin/Heidelberg: Springer Berlin Heidelberg
ID: ISSN: 0033-3158
Link: https://www.ncbi.nlm.nih.gov/pubmed/30617565
Zum Text:
SendSend as email Add to Book BagAdd to Book Bag
Staff View
recordid: cdi_proquest_journals_2164401422
title: Tobacco dependence is associated with increased risk for multi-morbid clustering of posttraumatic stress disorder, depressive disorder, and pain among post-9/11 deployed veterans
format: Article
creator:
  • Fonda, Jennifer R
  • Gregor, Kristin L
  • Fortier, Catherine B
  • Scioli-Salter, Erica R
  • McGlinchey, Regina E
  • Rasmusson, Ann
subjects:
  • Adult
  • Biomedical and Life Sciences
  • Biomedicine
  • Cohort Studies
  • Comorbidity
  • Dependence
  • Depressive Disorder - diagnosis
  • Depressive Disorder - epidemiology
  • Depressive Disorder - psychology
  • Disorders
  • Female
  • Humans
  • Male
  • Medical research
  • Medicine, Experimental
  • Mental depression
  • Middle Aged
  • Morbidity
  • Neurosciences
  • Original Investigation
  • Pain
  • Pain - diagnosis
  • Pain - epidemiology
  • Pain - psychology
  • Pharmacology/Toxicology
  • Post traumatic stress disorder
  • Posttraumatic stress disorder
  • Prevalence
  • Psychiatry
  • September 11 Terrorist Attacks - psychology
  • September 11 Terrorist Attacks - trends
  • Smoking cessation programs
  • Stress
  • Stress Disorders, Post-Traumatic - diagnosis
  • Stress Disorders, Post-Traumatic - epidemiology
  • Stress Disorders, Post-Traumatic - psychology
  • Tobacco
  • Tobacco Use Disorder - diagnosis
  • Tobacco Use Disorder - epidemiology
  • Tobacco Use Disorder - psychology
  • Veterans - psychology
ispartof: Psychopharmacology, 2019-01-07, Vol.236 (6), p.1729-1739
description: Rationale Tobacco use is highly prevalent among individuals with posttraumatic stress disorder (PTSD), depressive disorders, and pain. Research has revealed pairwise relationships among these conditions but has not examined more complex relationships that may influence symptom severity, chronicity, and treatment outcome. Objective To examine the clustering of current PTSD, depressive disorders, and clinically significant pain according to current tobacco use and dependence among post-9/11 deployed veterans. Methods Logistic regression was used to examine the clustering of these conditions in relationship to current tobacco use/dependence, while adjusting for age and total combat exposure, in 343 post-9/11 deployed veterans enrolled in the Translational Research Center for TBI and Stress Disorders (TRACTS) cohort ( M age = 32.1  +  8.3 years; 38% current tobacco use; 25% low and 12% moderate/high tobacco dependence). Results A three-way clustering of PTSD, depressive disorder, and pain was more likely than any single or pairwise combination of these conditions in moderate/high tobacco-dependent veterans compared to tobacco non-users (adjusted ORs = 3.50 to 4.18). This multi-morbidity cluster also was associated with increased PTSD severity. Conclusions Moderate to high dependence on tobacco is associated with substantially increased clustering of PTSD, depression, and clinically significant pain in veterans. Research examining synergistic interactions among these conditions, biological vulnerabilities shared among them, and the direct impact of tobacco use on the pathophysiology of PTSD, depression, and pain is needed. The results of such work may spur development of more effective integrated treatments to reduce the negative impact of these multi-morbid conditions on veterans’ wellbeing and long-term health.
language: eng
source:
identifier: ISSN: 0033-3158
fulltext: no_fulltext
issn:
  • 0033-3158
  • 1432-2072
url: Link


@attributes
NO1
SEARCH_ENGINEprimo_central_multiple_fe
SEARCH_ENGINE_TYPEPrimo Central Search Engine
RANK2.5538466
LOCALfalse
PrimoNMBib
record
control
sourceidgale_proqu
recordidTN_cdi_proquest_journals_2164401422
sourceformatXML
sourcesystemPC
galeidA591902152
sourcerecordidA591902152
originalsourceidFETCH-LOGICAL-c415t-23fff47a098237ca9e985792f32efd6df080a2f475506b65fdbec3db25f3751d0
addsrcrecordideNp1kctuFiEUx4nR2M_qA7gxJG5Ly2WYy7JprJo0cVPXhIFDpX4zjBympq_lE8rkq1YThQXh5H-B_Ah5Lfip4Lw7Q86lUIyLnmmhNWufkJ1olGSSd_Ip2XGuFFNC90fkBeItr6vpm-fkSPFWdLrVO_LjOo3WuUQ9LDB7mB3QiNQiJhdtAU-_x_KFxtllsFivOeJXGlKm07ovkU0pj9FTt1-xQI7zDU2BLglLyXadbImOYsmASH3ElD3kk61qm8Q7-GNoZ08XG2dqp1RTtgg2nAmxqffpvjbfQW2wM74kz4LdI7x6OI_J58t31xcf2NWn9x8vzq-Ya4QuTKoQQtNZPvRSdc4OMPS6G2RQEoJvfeA9t7IqtObt2OrgR3DKj1IH1Wnh-TF5e8hdcvq2AhZzm9Y810ojRds0XDRSPqpu7B5MnEOqP3dTRGfO9SCGSkhvqtN_qOr2MEWXZgixzv8yiIPB5YSYIZglx8nmeyO42eCbA3xT4ZsNvmmr583Dg9dxAv_b8Yt2FciDAJcNFeTHH_0_9Sexvbv9
sourcetypeAggregation Database
isCDItrue
recordtypearticle
pqid2164401422
display
typearticle
titleTobacco dependence is associated with increased risk for multi-morbid clustering of posttraumatic stress disorder, depressive disorder, and pain among post-9/11 deployed veterans
creatorFonda, Jennifer R ; Gregor, Kristin L ; Fortier, Catherine B ; Scioli-Salter, Erica R ; McGlinchey, Regina E ; Rasmusson, Ann
creatorcontribFonda, Jennifer R ; Gregor, Kristin L ; Fortier, Catherine B ; Scioli-Salter, Erica R ; McGlinchey, Regina E ; Rasmusson, Ann
descriptionRationale Tobacco use is highly prevalent among individuals with posttraumatic stress disorder (PTSD), depressive disorders, and pain. Research has revealed pairwise relationships among these conditions but has not examined more complex relationships that may influence symptom severity, chronicity, and treatment outcome. Objective To examine the clustering of current PTSD, depressive disorders, and clinically significant pain according to current tobacco use and dependence among post-9/11 deployed veterans. Methods Logistic regression was used to examine the clustering of these conditions in relationship to current tobacco use/dependence, while adjusting for age and total combat exposure, in 343 post-9/11 deployed veterans enrolled in the Translational Research Center for TBI and Stress Disorders (TRACTS) cohort ( M age = 32.1  +  8.3 years; 38% current tobacco use; 25% low and 12% moderate/high tobacco dependence). Results A three-way clustering of PTSD, depressive disorder, and pain was more likely than any single or pairwise combination of these conditions in moderate/high tobacco-dependent veterans compared to tobacco non-users (adjusted ORs = 3.50 to 4.18). This multi-morbidity cluster also was associated with increased PTSD severity. Conclusions Moderate to high dependence on tobacco is associated with substantially increased clustering of PTSD, depression, and clinically significant pain in veterans. Research examining synergistic interactions among these conditions, biological vulnerabilities shared among them, and the direct impact of tobacco use on the pathophysiology of PTSD, depression, and pain is needed. The results of such work may spur development of more effective integrated treatments to reduce the negative impact of these multi-morbid conditions on veterans’ wellbeing and long-term health.
identifier
0ISSN: 0033-3158
1EISSN: 1432-2072
2DOI: 10.1007/s00213-018-5155-6
3PMID: 30617565
languageeng
publisherBerlin/Heidelberg: Springer Berlin Heidelberg
subjectAdult ; Biomedical and Life Sciences ; Biomedicine ; Cohort Studies ; Comorbidity ; Dependence ; Depressive Disorder - diagnosis ; Depressive Disorder - epidemiology ; Depressive Disorder - psychology ; Disorders ; Female ; Humans ; Male ; Medical research ; Medicine, Experimental ; Mental depression ; Middle Aged ; Morbidity ; Neurosciences ; Original Investigation ; Pain ; Pain - diagnosis ; Pain - epidemiology ; Pain - psychology ; Pharmacology/Toxicology ; Post traumatic stress disorder ; Posttraumatic stress disorder ; Prevalence ; Psychiatry ; September 11 Terrorist Attacks - psychology ; September 11 Terrorist Attacks - trends ; Smoking cessation programs ; Stress ; Stress Disorders, Post-Traumatic - diagnosis ; Stress Disorders, Post-Traumatic - epidemiology ; Stress Disorders, Post-Traumatic - psychology ; Tobacco ; Tobacco Use Disorder - diagnosis ; Tobacco Use Disorder - epidemiology ; Tobacco Use Disorder - psychology ; Veterans - psychology
ispartofPsychopharmacology, 2019-01-07, Vol.236 (6), p.1729-1739
rights
0This is a U.S. government work and not under copyright protection in the U.S.; foreign copyright protection may apply 2018 2019
1Psychopharmacology is a copyright of Springer, (2019). All Rights Reserved.
lds50peer_reviewed
citesFETCH-LOGICAL-c415t-23fff47a098237ca9e985792f32efd6df080a2f475506b65fdbec3db25f3751d0
orcidid0000-0001-9482-2918
links
openurl$$Topenurl_article
thumbnail$$Usyndetics_thumb_exl
backlink$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/30617565$$D View this record in MEDLINE/PubMed
search
creatorcontrib
0Fonda, Jennifer R
1Gregor, Kristin L
2Fortier, Catherine B
3Scioli-Salter, Erica R
4McGlinchey, Regina E
5Rasmusson, Ann
title
0Tobacco dependence is associated with increased risk for multi-morbid clustering of posttraumatic stress disorder, depressive disorder, and pain among post-9/11 deployed veterans
1Psychopharmacology
addtitle
0Psychopharmacology
1Psychopharmacology (Berl)
descriptionRationale Tobacco use is highly prevalent among individuals with posttraumatic stress disorder (PTSD), depressive disorders, and pain. Research has revealed pairwise relationships among these conditions but has not examined more complex relationships that may influence symptom severity, chronicity, and treatment outcome. Objective To examine the clustering of current PTSD, depressive disorders, and clinically significant pain according to current tobacco use and dependence among post-9/11 deployed veterans. Methods Logistic regression was used to examine the clustering of these conditions in relationship to current tobacco use/dependence, while adjusting for age and total combat exposure, in 343 post-9/11 deployed veterans enrolled in the Translational Research Center for TBI and Stress Disorders (TRACTS) cohort ( M age = 32.1  +  8.3 years; 38% current tobacco use; 25% low and 12% moderate/high tobacco dependence). Results A three-way clustering of PTSD, depressive disorder, and pain was more likely than any single or pairwise combination of these conditions in moderate/high tobacco-dependent veterans compared to tobacco non-users (adjusted ORs = 3.50 to 4.18). This multi-morbidity cluster also was associated with increased PTSD severity. Conclusions Moderate to high dependence on tobacco is associated with substantially increased clustering of PTSD, depression, and clinically significant pain in veterans. Research examining synergistic interactions among these conditions, biological vulnerabilities shared among them, and the direct impact of tobacco use on the pathophysiology of PTSD, depression, and pain is needed. The results of such work may spur development of more effective integrated treatments to reduce the negative impact of these multi-morbid conditions on veterans’ wellbeing and long-term health.
subject
0Adult
1Biomedical and Life Sciences
2Biomedicine
3Cohort Studies
4Comorbidity
5Dependence
6Depressive Disorder - diagnosis
7Depressive Disorder - epidemiology
8Depressive Disorder - psychology
9Disorders
10Female
11Humans
12Male
13Medical research
14Medicine, Experimental
15Mental depression
16Middle Aged
17Morbidity
18Neurosciences
19Original Investigation
20Pain
21Pain - diagnosis
22Pain - epidemiology
23Pain - psychology
24Pharmacology/Toxicology
25Post traumatic stress disorder
26Posttraumatic stress disorder
27Prevalence
28Psychiatry
29September 11 Terrorist Attacks - psychology
30September 11 Terrorist Attacks - trends
31Smoking cessation programs
32Stress
33Stress Disorders, Post-Traumatic - diagnosis
34Stress Disorders, Post-Traumatic - epidemiology
35Stress Disorders, Post-Traumatic - psychology
36Tobacco
37Tobacco Use Disorder - diagnosis
38Tobacco Use Disorder - epidemiology
39Tobacco Use Disorder - psychology
40Veterans - psychology
issn
00033-3158
11432-2072
fulltextfalse
rsrctypearticle
creationdate2019
recordtypearticle
recordideNp1kctuFiEUx4nR2M_qA7gxJG5Ly2WYy7JprJo0cVPXhIFDpX4zjBympq_lE8rkq1YThQXh5H-B_Ah5Lfip4Lw7Q86lUIyLnmmhNWufkJ1olGSSd_Ip2XGuFFNC90fkBeItr6vpm-fkSPFWdLrVO_LjOo3WuUQ9LDB7mB3QiNQiJhdtAU-_x_KFxtllsFivOeJXGlKm07ovkU0pj9FTt1-xQI7zDU2BLglLyXadbImOYsmASH3ElD3kk61qm8Q7-GNoZ08XG2dqp1RTtgg2nAmxqffpvjbfQW2wM74kz4LdI7x6OI_J58t31xcf2NWn9x8vzq-Ya4QuTKoQQtNZPvRSdc4OMPS6G2RQEoJvfeA9t7IqtObt2OrgR3DKj1IH1Wnh-TF5e8hdcvq2AhZzm9Y810ojRds0XDRSPqpu7B5MnEOqP3dTRGfO9SCGSkhvqtN_qOr2MEWXZgixzv8yiIPB5YSYIZglx8nmeyO42eCbA3xT4ZsNvmmr583Dg9dxAv_b8Yt2FciDAJcNFeTHH_0_9Sexvbv9
startdate20190107
enddate20190107
creator
0Fonda, Jennifer R
1Gregor, Kristin L
2Fortier, Catherine B
3Scioli-Salter, Erica R
4McGlinchey, Regina E
5Rasmusson, Ann
general
0Springer Berlin Heidelberg
1Springer
2Springer Nature B.V
scope
0CGR
1CUY
2CVF
3ECM
4EIF
5NPM
6AAYXX
7CITATION
8BSHEE
93V.
107QG
117QR
127RV
137TK
147X7
157XB
1688E
1788G
188AO
198FD
208FI
218FJ
228FK
23ABUWG
24AZQEC
25BENPR
26DWQXO
27FR3
28FYUFA
29GHDGH
30GNUQQ
31K9.
32KB0
33M0S
34M1P
35M2M
36NAPCQ
37P64
38PQEST
39PQQKQ
40PQUKI
41PRINS
42Q9U
orcididhttps://orcid.org/0000-0001-9482-2918
sort
creationdate20190107
titleTobacco dependence is associated with increased risk for multi-morbid clustering of posttraumatic stress disorder, depressive disorder, and pain among post-9/11 deployed veterans
authorFonda, Jennifer R ; Gregor, Kristin L ; Fortier, Catherine B ; Scioli-Salter, Erica R ; McGlinchey, Regina E ; Rasmusson, Ann
facets
frbrtype5
frbrgroupidcdi_FETCH-LOGICAL-c415t-23fff47a098237ca9e985792f32efd6df080a2f475506b65fdbec3db25f3751d0
rsrctypearticles
prefilterarticles
languageeng
creationdate2019
topic
0Adult
1Biomedical and Life Sciences
2Biomedicine
3Cohort Studies
4Comorbidity
5Dependence
6Depressive Disorder - diagnosis
7Depressive Disorder - epidemiology
8Depressive Disorder - psychology
9Disorders
10Female
11Humans
12Male
13Medical research
14Medicine, Experimental
15Mental depression
16Middle Aged
17Morbidity
18Neurosciences
19Original Investigation
20Pain
21Pain - diagnosis
22Pain - epidemiology
23Pain - psychology
24Pharmacology/Toxicology
25Post traumatic stress disorder
26Posttraumatic stress disorder
27Prevalence
28Psychiatry
29September 11 Terrorist Attacks - psychology
30September 11 Terrorist Attacks - trends
31Smoking cessation programs
32Stress
33Stress Disorders, Post-Traumatic - diagnosis
34Stress Disorders, Post-Traumatic - epidemiology
35Stress Disorders, Post-Traumatic - psychology
36Tobacco
37Tobacco Use Disorder - diagnosis
38Tobacco Use Disorder - epidemiology
39Tobacco Use Disorder - psychology
40Veterans - psychology
toplevelpeer_reviewed
creatorcontrib
0Fonda, Jennifer R
1Gregor, Kristin L
2Fortier, Catherine B
3Scioli-Salter, Erica R
4McGlinchey, Regina E
5Rasmusson, Ann
collection
0Medline
1MEDLINE
2MEDLINE (Ovid)
3MEDLINE
4MEDLINE
5PubMed
6CrossRef
7Academic OneFile (A&I only)
8ProQuest Central (Corporate)
9Animal Behavior Abstracts
10Chemoreception Abstracts
11Nursing & Allied Health Database
12Neurosciences Abstracts
13Health & Medical Collection
14ProQuest Central (purchase pre-March 2016)
15Medical Database (Alumni Edition)
16Psychology Database (Alumni)
17ProQuest Pharma Collection
18Technology Research Database
19Hospital Premium Collection
20Hospital Premium Collection (Alumni Edition)
21ProQuest Central (Alumni) (purchase pre-March 2016)
22ProQuest Central (Alumni Edition)
23ProQuest Central Essentials
24ProQuest Central
25ProQuest Central Korea
26Engineering Research Database
27Health Research Premium Collection
28Health Research Premium Collection (Alumni)
29ProQuest Central Student
30ProQuest Health & Medical Complete (Alumni)
31Nursing & Allied Health Database (Alumni Edition)
32Health & Medical Collection (Alumni Edition)
33Medical Database
34Psychology Database
35Nursing & Allied Health Premium
36Biotechnology and BioEngineering Abstracts
37ProQuest One Academic Eastern Edition
38ProQuest One Academic
39ProQuest One Academic UKI Edition
40ProQuest Central China
41ProQuest Central Basic
jtitlePsychopharmacology
delivery
delcategoryRemote Search Resource
fulltextno_fulltext
addata
au
0Fonda, Jennifer R
1Gregor, Kristin L
2Fortier, Catherine B
3Scioli-Salter, Erica R
4McGlinchey, Regina E
5Rasmusson, Ann
formatjournal
genrearticle
ristypeJOUR
atitleTobacco dependence is associated with increased risk for multi-morbid clustering of posttraumatic stress disorder, depressive disorder, and pain among post-9/11 deployed veterans
jtitlePsychopharmacology
stitlePsychopharmacology
addtitlePsychopharmacology (Berl)
date2019-01-07
risdate2019
volume236
issue6
spage1729
epage1739
pages1729-1739
issn0033-3158
eissn1432-2072
abstractRationale Tobacco use is highly prevalent among individuals with posttraumatic stress disorder (PTSD), depressive disorders, and pain. Research has revealed pairwise relationships among these conditions but has not examined more complex relationships that may influence symptom severity, chronicity, and treatment outcome. Objective To examine the clustering of current PTSD, depressive disorders, and clinically significant pain according to current tobacco use and dependence among post-9/11 deployed veterans. Methods Logistic regression was used to examine the clustering of these conditions in relationship to current tobacco use/dependence, while adjusting for age and total combat exposure, in 343 post-9/11 deployed veterans enrolled in the Translational Research Center for TBI and Stress Disorders (TRACTS) cohort ( M age = 32.1  +  8.3 years; 38% current tobacco use; 25% low and 12% moderate/high tobacco dependence). Results A three-way clustering of PTSD, depressive disorder, and pain was more likely than any single or pairwise combination of these conditions in moderate/high tobacco-dependent veterans compared to tobacco non-users (adjusted ORs = 3.50 to 4.18). This multi-morbidity cluster also was associated with increased PTSD severity. Conclusions Moderate to high dependence on tobacco is associated with substantially increased clustering of PTSD, depression, and clinically significant pain in veterans. Research examining synergistic interactions among these conditions, biological vulnerabilities shared among them, and the direct impact of tobacco use on the pathophysiology of PTSD, depression, and pain is needed. The results of such work may spur development of more effective integrated treatments to reduce the negative impact of these multi-morbid conditions on veterans’ wellbeing and long-term health.
copBerlin/Heidelberg
pubSpringer Berlin Heidelberg
pmid30617565
doi10.1007/s00213-018-5155-6
orcididhttps://orcid.org/0000-0001-9482-2918