schliessen

Filtern

 

Bibliotheken

Plasma Antioxidants and Asymptomatic Carotid Atherosclerotic Disease

Background: Atherosclerosis remains clinically mute for a long time and frequently manifests itself with an acute cardiovascular event. The possibility of detecting this disease in a subclinical phase and reducing or reversing its progression is an issue of relevance. Published studies on the associ... Full description

Journal Title: Annals of nutrition and metabolism 2008, Vol.53 (2), p.86-90
Main Author: Riccioni, Graziano
Other Authors: Bucciarelli, Tonino , D’Orazio, Nicolantonio , Palumbo, Nicola , di Ilio, Emanuela , Corradi, Francesco , Pennelli, Alfonso , Bazzano, Lydia A
Format: Electronic Article Electronic Article
Language: English
Subjects:
Quelle: Alma/SFX Local Collection
Publisher: Basel, Switzerland: S. Karger AG
ID: ISSN: 0250-6807
Link: https://www.ncbi.nlm.nih.gov/pubmed/18936536
Zum Text:
SendSend as email Add to Book BagAdd to Book Bag
Staff View
recordid: cdi_proquest_journals_232101658
title: Plasma Antioxidants and Asymptomatic Carotid Atherosclerotic Disease
format: Article
creator:
  • Riccioni, Graziano
  • Bucciarelli, Tonino
  • D’Orazio, Nicolantonio
  • Palumbo, Nicola
  • di Ilio, Emanuela
  • Corradi, Francesco
  • Pennelli, Alfonso
  • Bazzano, Lydia A
subjects:
  • Aged
  • Antioxidants
  • Antioxidants - metabolism
  • beta Carotene - administration & dosage
  • beta Carotene - blood
  • Biomarkers - blood
  • Body Mass Index
  • Cardiovascular disease
  • Carotenoids - administration & dosage
  • Carotenoids - blood
  • Carotid Artery Diseases - blood
  • Carotid Artery Diseases - diagnostic imaging
  • Cholesterol, HDL - blood
  • Coronary vessels
  • Hemoglobins - metabolism
  • Humans
  • Male
  • Middle Aged
  • Nutrition
  • Original Paper
  • Tunica Intima - anatomy & histology
  • Tunica Intima - pathology
  • Ultrasonography
  • Vitamin A
  • Vitamin A - administration & dosage
  • Vitamin A - blood
  • Vitamin E
  • Vitamin E - administration & dosage
  • Vitamin E - blood
  • Vitamins - administration & dosage
  • Vitamins - blood
ispartof: Annals of nutrition and metabolism, 2008, Vol.53 (2), p.86-90
description: Background: Atherosclerosis remains clinically mute for a long time and frequently manifests itself with an acute cardiovascular event. The possibility of detecting this disease in a subclinical phase and reducing or reversing its progression is an issue of relevance. Published studies on the association between antioxidant vitamins and carotenoids and carotid intima-media thickness (CIMT) have been inconclusive. Methods: We enrolled 220 consecutive, asymptomatic participants. After carotid ultrasound investigation, a medical history was taken, a physical examination was performed and venous blood samples were collected. Venous blood samples were analyzed for concentrations of antioxidant vitamins and carotenoids. Results: Low concentrations of vitamin A (p < 0.01), vitamin E (p < 0.001), lycopene (p < 0.01) and β-carotene (p < 0.001) were significantly associated with carotid atherosclerosis (CIMT ≧0.8 mm). In addition, marginally higher body mass index, plasma haemoglobin and high-density lipoprotein cholesterol were also associated with carotid atherosclerosis, while other laboratory parameters considered in this study (total cholesterol, low-density lipoprotein cholesterol, triglycerides and C-reactive protein) were not significantly associated with carotid atherosclerosis. Conclusions: Low plasma concentrations of antioxidant vitamins (A, E, β-carotene) and lycopene were associated with early carotid atherosclerotic lesions as measured by CIMT. Regular intake of foods rich in lycopene and antioxidant vitamins may slow the progression of atherosclerosis.
language: eng
source: Alma/SFX Local Collection
identifier: ISSN: 0250-6807
fulltext: fulltext
issn:
  • 0250-6807
  • 1421-9697
url: Link


@attributes
NO1
SEARCH_ENGINEprimo_central_multiple_fe
SEARCH_ENGINE_TYPEPrimo Central Search Engine
RANK2.2266114
LOCALfalse
PrimoNMBib
record
control
sourceidjstor_proqu
recordidTN_cdi_proquest_journals_232101658
sourceformatXML
sourcesystemPC
jstor_id48507760
sourcerecordid48507760
originalsourceidFETCH-LOGICAL-c353t-5f8fa19cc0b5fb60fff3d1c8f0da4436053f2525c16928938e2aaca5bb00bb7c3
addsrcrecordideNptkM9rHCEUgCW0JJs0h_wBLUMPgRymeero6HHZNEkh_XFoz8MbR1u3M-NWXWj--7rskkDoQUT5-HjvI-SCwgdKhb4GACobqekRWdCG0VpL3b4iC2ACaqmgPSGnKa0LxVQjjskJVZpLweWC3HwbMU1YLefsw18_4JxThfNQLdPjtMlhwuxNtcIYsi-f-ZeNIZnR7t6muvHJYrJvyGuHY7Lnh_uM_Lj9-H11Xz98vfu0Wj7Uhguea-GUQ6qNgV64XoJzjg_UKAcDNg2XILhjgglDpWZlQmUZokHR9wB93xp-Ri733k0Mf7Y25W7yydhxxNmGbeqkVrwcXcD3L8B12Ma5zNYxzmipJVSBrvaQKSulaF23iX7C-NhR6HZdu6euhX13EG77yQ7P5CFkAa5fyIzPpV2Yc0Q__ld5WOY3xp82PimXXz4zAFViADBQO_XbPbhOOTxzjRLQthL4PwRElls
sourcetypeAggregation Database
isCDItrue
recordtypearticle
pqid232101658
display
typearticle
titlePlasma Antioxidants and Asymptomatic Carotid Atherosclerotic Disease
sourceAlma/SFX Local Collection
creatorRiccioni, Graziano ; Bucciarelli, Tonino ; D’Orazio, Nicolantonio ; Palumbo, Nicola ; di Ilio, Emanuela ; Corradi, Francesco ; Pennelli, Alfonso ; Bazzano, Lydia A
creatorcontribRiccioni, Graziano ; Bucciarelli, Tonino ; D’Orazio, Nicolantonio ; Palumbo, Nicola ; di Ilio, Emanuela ; Corradi, Francesco ; Pennelli, Alfonso ; Bazzano, Lydia A
descriptionBackground: Atherosclerosis remains clinically mute for a long time and frequently manifests itself with an acute cardiovascular event. The possibility of detecting this disease in a subclinical phase and reducing or reversing its progression is an issue of relevance. Published studies on the association between antioxidant vitamins and carotenoids and carotid intima-media thickness (CIMT) have been inconclusive. Methods: We enrolled 220 consecutive, asymptomatic participants. After carotid ultrasound investigation, a medical history was taken, a physical examination was performed and venous blood samples were collected. Venous blood samples were analyzed for concentrations of antioxidant vitamins and carotenoids. Results: Low concentrations of vitamin A (p < 0.01), vitamin E (p < 0.001), lycopene (p < 0.01) and β-carotene (p < 0.001) were significantly associated with carotid atherosclerosis (CIMT ≧0.8 mm). In addition, marginally higher body mass index, plasma haemoglobin and high-density lipoprotein cholesterol were also associated with carotid atherosclerosis, while other laboratory parameters considered in this study (total cholesterol, low-density lipoprotein cholesterol, triglycerides and C-reactive protein) were not significantly associated with carotid atherosclerosis. Conclusions: Low plasma concentrations of antioxidant vitamins (A, E, β-carotene) and lycopene were associated with early carotid atherosclerotic lesions as measured by CIMT. Regular intake of foods rich in lycopene and antioxidant vitamins may slow the progression of atherosclerosis.
identifier
0ISSN: 0250-6807
1EISSN: 1421-9697
2DOI: 10.1159/000164691
3PMID: 18936536
languageeng
publisherBasel, Switzerland: S. Karger AG
subject
ispartofAnnals of nutrition and metabolism, 2008, Vol.53 (2), p.86-90
rights
02008 S. Karger AG
12008 S. Karger AG, Basel
2Copyright (c) 2008 S. Karger AG, Basel
lds50peer_reviewed
citedbyFETCH-LOGICAL-c353t-5f8fa19cc0b5fb60fff3d1c8f0da4436053f2525c16928938e2aaca5bb00bb7c3
citesFETCH-LOGICAL-c353t-5f8fa19cc0b5fb60fff3d1c8f0da4436053f2525c16928938e2aaca5bb00bb7c3
links
openurl$$Topenurl_article
openurlfulltext$$Topenurlfull_article
thumbnail$$Usyndetics_thumb_exl
backlink$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/18936536$$D View this record in MEDLINE/PubMed
search
creatorcontrib
0Riccioni, Graziano
1Bucciarelli, Tonino
2D’Orazio, Nicolantonio
3Palumbo, Nicola
4di Ilio, Emanuela
5Corradi, Francesco
6Pennelli, Alfonso
7Bazzano, Lydia A
title
0Plasma Antioxidants and Asymptomatic Carotid Atherosclerotic Disease
1Annals of nutrition and metabolism
addtitleAnn Nutr Metab
descriptionBackground: Atherosclerosis remains clinically mute for a long time and frequently manifests itself with an acute cardiovascular event. The possibility of detecting this disease in a subclinical phase and reducing or reversing its progression is an issue of relevance. Published studies on the association between antioxidant vitamins and carotenoids and carotid intima-media thickness (CIMT) have been inconclusive. Methods: We enrolled 220 consecutive, asymptomatic participants. After carotid ultrasound investigation, a medical history was taken, a physical examination was performed and venous blood samples were collected. Venous blood samples were analyzed for concentrations of antioxidant vitamins and carotenoids. Results: Low concentrations of vitamin A (p < 0.01), vitamin E (p < 0.001), lycopene (p < 0.01) and β-carotene (p < 0.001) were significantly associated with carotid atherosclerosis (CIMT ≧0.8 mm). In addition, marginally higher body mass index, plasma haemoglobin and high-density lipoprotein cholesterol were also associated with carotid atherosclerosis, while other laboratory parameters considered in this study (total cholesterol, low-density lipoprotein cholesterol, triglycerides and C-reactive protein) were not significantly associated with carotid atherosclerosis. Conclusions: Low plasma concentrations of antioxidant vitamins (A, E, β-carotene) and lycopene were associated with early carotid atherosclerotic lesions as measured by CIMT. Regular intake of foods rich in lycopene and antioxidant vitamins may slow the progression of atherosclerosis.
subject
0Aged
1Antioxidants
2Antioxidants - metabolism
3beta Carotene - administration & dosage
4beta Carotene - blood
5Biomarkers - blood
6Body Mass Index
7Cardiovascular disease
8Carotenoids - administration & dosage
9Carotenoids - blood
10Carotid Artery Diseases - blood
11Carotid Artery Diseases - diagnostic imaging
12Cholesterol, HDL - blood
13Coronary vessels
14Hemoglobins - metabolism
15Humans
16Male
17Middle Aged
18Nutrition
19Original Paper
20Tunica Intima - anatomy & histology
21Tunica Intima - pathology
22Ultrasonography
23Vitamin A
24Vitamin A - administration & dosage
25Vitamin A - blood
26Vitamin E
27Vitamin E - administration & dosage
28Vitamin E - blood
29Vitamins - administration & dosage
30Vitamins - blood
issn
00250-6807
11421-9697
fulltexttrue
rsrctypearticle
creationdate2008
recordtypearticle
recordideNptkM9rHCEUgCW0JJs0h_wBLUMPgRymeero6HHZNEkh_XFoz8MbR1u3M-NWXWj--7rskkDoQUT5-HjvI-SCwgdKhb4GACobqekRWdCG0VpL3b4iC2ACaqmgPSGnKa0LxVQjjskJVZpLweWC3HwbMU1YLefsw18_4JxThfNQLdPjtMlhwuxNtcIYsi-f-ZeNIZnR7t6muvHJYrJvyGuHY7Lnh_uM_Lj9-H11Xz98vfu0Wj7Uhguea-GUQ6qNgV64XoJzjg_UKAcDNg2XILhjgglDpWZlQmUZokHR9wB93xp-Ri733k0Mf7Y25W7yydhxxNmGbeqkVrwcXcD3L8B12Ma5zNYxzmipJVSBrvaQKSulaF23iX7C-NhR6HZdu6euhX13EG77yQ7P5CFkAa5fyIzPpV2Yc0Q__ld5WOY3xp82PimXXz4zAFViADBQO_XbPbhOOTxzjRLQthL4PwRElls
startdate20080101
enddate20080101
creator
0Riccioni, Graziano
1Bucciarelli, Tonino
2D’Orazio, Nicolantonio
3Palumbo, Nicola
4di Ilio, Emanuela
5Corradi, Francesco
6Pennelli, Alfonso
7Bazzano, Lydia A
generalS. Karger AG
scope
0CGR
1CUY
2CVF
3ECM
4EIF
5NPM
6AAYXX
7CITATION
83V.
97QP
107RV
117X2
127X7
137XB
1488E
1588I
168AF
178AO
188C1
198FE
208FH
218FI
228FJ
238FK
248G5
25ABUWG
26ATCPS
27AZQEC
28BEC
29BENPR
30BHPHI
31DWQXO
32FYUFA
33GHDGH
34GNUQQ
35GUQSH
36HCIFZ
37K9-
38K9.
39KB0
40M0K
41M0R
42M0S
43M1P
44M2O
45M2P
46MBDVC
47NAPCQ
48PADUT
49PQEST
50PQQKQ
51PQUKI
52PRINS
53Q9U
547X8
sort
creationdate20080101
titlePlasma Antioxidants and Asymptomatic Carotid Atherosclerotic Disease
authorRiccioni, Graziano ; Bucciarelli, Tonino ; D’Orazio, Nicolantonio ; Palumbo, Nicola ; di Ilio, Emanuela ; Corradi, Francesco ; Pennelli, Alfonso ; Bazzano, Lydia A
facets
frbrtype5
frbrgroupidcdi_FETCH-LOGICAL-c353t-5f8fa19cc0b5fb60fff3d1c8f0da4436053f2525c16928938e2aaca5bb00bb7c3
rsrctypearticles
prefilterarticles
languageeng
creationdate2008
topic
0Aged
1Antioxidants
2Antioxidants - metabolism
3beta Carotene - administration & dosage
4beta Carotene - blood
5Biomarkers - blood
6Body Mass Index
7Cardiovascular disease
8Carotenoids - administration & dosage
9Carotenoids - blood
10Carotid Artery Diseases - blood
11Carotid Artery Diseases - diagnostic imaging
12Cholesterol, HDL - blood
13Coronary vessels
14Hemoglobins - metabolism
15Humans
16Male
17Middle Aged
18Nutrition
19Original Paper
20Tunica Intima - anatomy & histology
21Tunica Intima - pathology
22Ultrasonography
23Vitamin A
24Vitamin A - administration & dosage
25Vitamin A - blood
26Vitamin E
27Vitamin E - administration & dosage
28Vitamin E - blood
29Vitamins - administration & dosage
30Vitamins - blood
toplevel
0peer_reviewed
1online_resources
creatorcontrib
0Riccioni, Graziano
1Bucciarelli, Tonino
2D’Orazio, Nicolantonio
3Palumbo, Nicola
4di Ilio, Emanuela
5Corradi, Francesco
6Pennelli, Alfonso
7Bazzano, Lydia A
collection
0Medline
1MEDLINE
2MEDLINE (Ovid)
3MEDLINE
4MEDLINE
5PubMed
6CrossRef
7ProQuest Central (Corporate)
8Calcium & Calcified Tissue Abstracts
9Nursing & Allied Health Database
10Agricultural Science Collection
11Health & Medical Collection
12ProQuest Central (purchase pre-March 2016)
13Medical Database (Alumni Edition)
14Science Database (Alumni Edition)
15STEM Database
16ProQuest Pharma Collection
17Public Health Database
18ProQuest SciTech Collection
19ProQuest Natural Science Collection
20Hospital Premium Collection
21Hospital Premium Collection (Alumni Edition)
22ProQuest Central (Alumni) (purchase pre-March 2016)
23Research Library (Alumni Edition)
24ProQuest Central (Alumni Edition)
25Agricultural & Environmental Science Collection
26ProQuest Central Essentials
27eLibrary
28ProQuest Central
29Natural Science Collection
30ProQuest Central Korea
31Health Research Premium Collection
32Health Research Premium Collection (Alumni)
33ProQuest Central Student
34Research Library Prep
35SciTech Premium Collection
36Consumer Health Database (Alumni Edition)
37ProQuest Health & Medical Complete (Alumni)
38Nursing & Allied Health Database (Alumni Edition)
39Agricultural Science Database
40Consumer Health Database
41Health & Medical Collection (Alumni Edition)
42Medical Database
43Research Library
44Science Database
45Research Library (Corporate)
46Nursing & Allied Health Premium
47Research Library China
48ProQuest One Academic Eastern Edition
49ProQuest One Academic
50ProQuest One Academic UKI Edition
51ProQuest Central China
52ProQuest Central Basic
53MEDLINE - Academic
jtitleAnnals of nutrition and metabolism
delivery
delcategoryRemote Search Resource
fulltextfulltext
addata
au
0Riccioni, Graziano
1Bucciarelli, Tonino
2D’Orazio, Nicolantonio
3Palumbo, Nicola
4di Ilio, Emanuela
5Corradi, Francesco
6Pennelli, Alfonso
7Bazzano, Lydia A
formatjournal
genrearticle
ristypeJOUR
atitlePlasma Antioxidants and Asymptomatic Carotid Atherosclerotic Disease
jtitleAnnals of nutrition and metabolism
addtitleAnn Nutr Metab
date2008-01-01
risdate2008
volume53
issue2
spage86
epage90
pages86-90
issn0250-6807
eissn1421-9697
abstractBackground: Atherosclerosis remains clinically mute for a long time and frequently manifests itself with an acute cardiovascular event. The possibility of detecting this disease in a subclinical phase and reducing or reversing its progression is an issue of relevance. Published studies on the association between antioxidant vitamins and carotenoids and carotid intima-media thickness (CIMT) have been inconclusive. Methods: We enrolled 220 consecutive, asymptomatic participants. After carotid ultrasound investigation, a medical history was taken, a physical examination was performed and venous blood samples were collected. Venous blood samples were analyzed for concentrations of antioxidant vitamins and carotenoids. Results: Low concentrations of vitamin A (p < 0.01), vitamin E (p < 0.001), lycopene (p < 0.01) and β-carotene (p < 0.001) were significantly associated with carotid atherosclerosis (CIMT ≧0.8 mm). In addition, marginally higher body mass index, plasma haemoglobin and high-density lipoprotein cholesterol were also associated with carotid atherosclerosis, while other laboratory parameters considered in this study (total cholesterol, low-density lipoprotein cholesterol, triglycerides and C-reactive protein) were not significantly associated with carotid atherosclerosis. Conclusions: Low plasma concentrations of antioxidant vitamins (A, E, β-carotene) and lycopene were associated with early carotid atherosclerotic lesions as measured by CIMT. Regular intake of foods rich in lycopene and antioxidant vitamins may slow the progression of atherosclerosis.
copBasel, Switzerland
pubS. Karger AG
pmid18936536
doi10.1159/000164691
tpages5