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Highlights from the literature

Treatment with caffeine seems to confer positive advantages on preterm babies, and the CAP trial just goes on giving. …but all AEDs can be harmful to fetuses The EURAP register of pregnant women treated with anti-epileptic drugs has yielded high quality data on the relative risks of different AEDs a... Full description

Journal Title: Archives of disease in childhood. Fetal and neonatal edition 2018-07, Vol.103 (4), p.F396-F396
Main Author: Ward Platt, Martin
Format: Electronic Article Electronic Article
Language: English
Subjects:
Publisher: England: BMJ Publishing Group LTD
ID: ISSN: 1359-2998
Link: https://www.ncbi.nlm.nih.gov/pubmed/30006472
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title: Highlights from the literature
format: Article
creator:
  • Ward Platt, Martin
subjects:
  • Antibiotics
  • Breastfeeding & lactation
  • Caffeine
  • Drug dosages
  • Nonsteroidal anti-inflammatory drugs
  • Pediatrics
ispartof: Archives of disease in childhood. Fetal and neonatal edition, 2018-07, Vol.103 (4), p.F396-F396
description: Treatment with caffeine seems to confer positive advantages on preterm babies, and the CAP trial just goes on giving. …but all AEDs can be harmful to fetuses The EURAP register of pregnant women treated with anti-epileptic drugs has yielded high quality data on the relative risks of different AEDs at different doses for major congenital malformation (Lancet DOI: 10.1016/S1474-4422(18)30107-8). The European Medicines Agency Pharmacovigilance Risk Assessment Committee and the UK MHRA have advised that valproate should only be used in women of childbearing potential if nothing else works, and avoided altogether in pregnancy for non-epilepsy indications such as migraine or bipolar disorder. In a randomised design 164 mother-baby pairs were allocated either to usual full breast feeding or to 10 mL supplements of formula after each breast feed, stopped at the onset of effective milk production (J Peds DOI: 10.1016/j.jpeds.2017.12.073).
language: eng
source:
identifier: ISSN: 1359-2998
fulltext: no_fulltext
issn:
  • 1359-2998
  • 1468-2052
url: Link


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descriptionTreatment with caffeine seems to confer positive advantages on preterm babies, and the CAP trial just goes on giving. …but all AEDs can be harmful to fetuses The EURAP register of pregnant women treated with anti-epileptic drugs has yielded high quality data on the relative risks of different AEDs at different doses for major congenital malformation (Lancet DOI: 10.1016/S1474-4422(18)30107-8). The European Medicines Agency Pharmacovigilance Risk Assessment Committee and the UK MHRA have advised that valproate should only be used in women of childbearing potential if nothing else works, and avoided altogether in pregnancy for non-epilepsy indications such as migraine or bipolar disorder. In a randomised design 164 mother-baby pairs were allocated either to usual full breast feeding or to 10 mL supplements of formula after each breast feed, stopped at the onset of effective milk production (J Peds DOI: 10.1016/j.jpeds.2017.12.073).
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abstractTreatment with caffeine seems to confer positive advantages on preterm babies, and the CAP trial just goes on giving. …but all AEDs can be harmful to fetuses The EURAP register of pregnant women treated with anti-epileptic drugs has yielded high quality data on the relative risks of different AEDs at different doses for major congenital malformation (Lancet DOI: 10.1016/S1474-4422(18)30107-8). The European Medicines Agency Pharmacovigilance Risk Assessment Committee and the UK MHRA have advised that valproate should only be used in women of childbearing potential if nothing else works, and avoided altogether in pregnancy for non-epilepsy indications such as migraine or bipolar disorder. In a randomised design 164 mother-baby pairs were allocated either to usual full breast feeding or to 10 mL supplements of formula after each breast feed, stopped at the onset of effective milk production (J Peds DOI: 10.1016/j.jpeds.2017.12.073).
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