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Response to antiretroviral therapy in occult hepatitis B and HIV co-infection in West Africa

This study evaluated the outcome of first-line antiretroviral therapy among 35 Ghanaians with occult HBV/HIV co-infection, comparing them over 2 years to 120 patients with HBsAg+ HBV/HIV co-infection and 230 patients without HBV co-infection. Increases in CD4 cell count and BMI were similar, whereas... Full description

Journal Title: AIDS (London) 2013, Vol.27 (1), p.139-144
Main Author: CHADWICK, David
Other Authors: STANLEY, Alastair , SARFO, Stephen , APPIAH, Lambert , ANKCORN, Michael , FOSTER, Geraldine , SCHWAB, Uli , PHILLIPS, Richard , GERETTI, Anna M
Format: Electronic Article Electronic Article
Language: English
Subjects:
Publisher: Hagerstown, MD: Lippincott Williams & Wilkins
ID: ISSN: 0269-9370
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title: Response to antiretroviral therapy in occult hepatitis B and HIV co-infection in West Africa
format: Article
creator:
  • CHADWICK, David
  • STANLEY, Alastair
  • SARFO, Stephen
  • APPIAH, Lambert
  • ANKCORN, Michael
  • FOSTER, Geraldine
  • SCHWAB, Uli
  • PHILLIPS, Richard
  • GERETTI, Anna M
subjects:
  • Anti-HIV Agents - therapeutic use
  • Antibiotics. Antiinfectious agents. Antiparasitic agents
  • antiretroviral therapy
  • Antiviral agents
  • Biological and medical sciences
  • Body Mass Index
  • CD4 antigen
  • CD4 Lymphocyte Count
  • Coinfection
  • Disease Progression
  • Female
  • Ghana - epidemiology
  • Hepatitis B
  • Hepatitis B - drug therapy
  • Hepatitis B - epidemiology
  • Hepatitis B - immunology
  • Hepatitis B Surface Antigens - blood
  • Hepatitis B virus
  • HIV Infections - drug therapy
  • HIV Infections - epidemiology
  • HIV Infections - immunology
  • Human immunodeficiency virus
  • Human viral diseases
  • Humans
  • Infectious diseases
  • Lamivudine - therapeutic use
  • Liver
  • Male
  • Medical sciences
  • Pharmacology. Drug treatments
  • Prevalence
  • Reverse Transcriptase Inhibitors - therapeutic use
  • transaminase
  • Treatment Outcome
  • Viral diseases
  • Viral diseases of the lymphoid tissue and the blood. Aids
  • Viral hepatitis
  • Viral Load - drug effects
ispartof: AIDS (London), 2013, Vol.27 (1), p.139-144
description: This study evaluated the outcome of first-line antiretroviral therapy among 35 Ghanaians with occult HBV/HIV co-infection, comparing them over 2 years to 120 patients with HBsAg+ HBV/HIV co-infection and 230 patients without HBV co-infection. Increases in CD4 cell count and BMI were similar, whereas elevations of hepatic transaminases were more frequent in both the occult HBV and HBsAg+ patients. Occult HBV/HIV co-infection appears not to impact adversely on response to antiretroviral therapy in Ghana.
language: eng
source:
identifier: ISSN: 0269-9370
fulltext: no_fulltext
issn:
  • 0269-9370
  • 1473-5571
url: Link


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titleResponse to antiretroviral therapy in occult hepatitis B and HIV co-infection in West Africa
creatorCHADWICK, David ; STANLEY, Alastair ; SARFO, Stephen ; APPIAH, Lambert ; ANKCORN, Michael ; FOSTER, Geraldine ; SCHWAB, Uli ; PHILLIPS, Richard ; GERETTI, Anna M
creatorcontribCHADWICK, David ; STANLEY, Alastair ; SARFO, Stephen ; APPIAH, Lambert ; ANKCORN, Michael ; FOSTER, Geraldine ; SCHWAB, Uli ; PHILLIPS, Richard ; GERETTI, Anna M
descriptionThis study evaluated the outcome of first-line antiretroviral therapy among 35 Ghanaians with occult HBV/HIV co-infection, comparing them over 2 years to 120 patients with HBsAg+ HBV/HIV co-infection and 230 patients without HBV co-infection. Increases in CD4 cell count and BMI were similar, whereas elevations of hepatic transaminases were more frequent in both the occult HBV and HBsAg+ patients. Occult HBV/HIV co-infection appears not to impact adversely on response to antiretroviral therapy in Ghana.
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languageeng
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subjectAnti-HIV Agents - therapeutic use ; Antibiotics. Antiinfectious agents. Antiparasitic agents ; antiretroviral therapy ; Antiviral agents ; Biological and medical sciences ; Body Mass Index ; CD4 antigen ; CD4 Lymphocyte Count ; Coinfection ; Disease Progression ; Female ; Ghana - epidemiology ; Hepatitis B ; Hepatitis B - drug therapy ; Hepatitis B - epidemiology ; Hepatitis B - immunology ; Hepatitis B Surface Antigens - blood ; Hepatitis B virus ; HIV Infections - drug therapy ; HIV Infections - epidemiology ; HIV Infections - immunology ; Human immunodeficiency virus ; Human viral diseases ; Humans ; Infectious diseases ; Lamivudine - therapeutic use ; Liver ; Male ; Medical sciences ; Pharmacology. Drug treatments ; Prevalence ; Reverse Transcriptase Inhibitors - therapeutic use ; transaminase ; Treatment Outcome ; Viral diseases ; Viral diseases of the lymphoid tissue and the blood. Aids ; Viral hepatitis ; Viral Load - drug effects
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descriptionThis study evaluated the outcome of first-line antiretroviral therapy among 35 Ghanaians with occult HBV/HIV co-infection, comparing them over 2 years to 120 patients with HBsAg+ HBV/HIV co-infection and 230 patients without HBV co-infection. Increases in CD4 cell count and BMI were similar, whereas elevations of hepatic transaminases were more frequent in both the occult HBV and HBsAg+ patients. Occult HBV/HIV co-infection appears not to impact adversely on response to antiretroviral therapy in Ghana.
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1Antibiotics. Antiinfectious agents. Antiparasitic agents
2antiretroviral therapy
3Antiviral agents
4Biological and medical sciences
5Body Mass Index
6CD4 antigen
7CD4 Lymphocyte Count
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12Hepatitis B
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14Hepatitis B - epidemiology
15Hepatitis B - immunology
16Hepatitis B Surface Antigens - blood
17Hepatitis B virus
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19HIV Infections - epidemiology
20HIV Infections - immunology
21Human immunodeficiency virus
22Human viral diseases
23Humans
24Infectious diseases
25Lamivudine - therapeutic use
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30Prevalence
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32transaminase
33Treatment Outcome
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36Viral hepatitis
37Viral Load - drug effects
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titleResponse to antiretroviral therapy in occult hepatitis B and HIV co-infection in West Africa
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6CD4 antigen
7CD4 Lymphocyte Count
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21Human immunodeficiency virus
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36Viral hepatitis
37Viral Load - drug effects
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pages139-144
issn0269-9370
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abstractThis study evaluated the outcome of first-line antiretroviral therapy among 35 Ghanaians with occult HBV/HIV co-infection, comparing them over 2 years to 120 patients with HBsAg+ HBV/HIV co-infection and 230 patients without HBV co-infection. Increases in CD4 cell count and BMI were similar, whereas elevations of hepatic transaminases were more frequent in both the occult HBV and HBsAg+ patients. Occult HBV/HIV co-infection appears not to impact adversely on response to antiretroviral therapy in Ghana.
copHagerstown, MD
pubLippincott Williams & Wilkins
pmid22874516
doi10.1097/QAD.0b013e3283589879