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Stress and Cardiovascular Disease: An Update on Current Knowledge

Considerable progress has been made during the past decade in research on cardiovascular effects of stress. Early-life stressors, such as childhood abuse and early socioeconomic adversity, are linked to increased cardiovascular morbidity in adulthood. Our updated meta-analyses of prospective studies... Full description

Journal Title: Annual review of public health 2013, Vol.34 (1), p.337-354
Main Author: STEPTOE, Andrew
Other Authors: KIVIMÄKI, Mika
Format: Electronic Article Electronic Article
Language: English
Subjects:
Publisher: Palo Alto, CA: Annual Reviews
ID: ISSN: 0163-7525
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recordid: cdi_proquest_miscellaneous_1319158833
title: Stress and Cardiovascular Disease: An Update on Current Knowledge
format: Article
creator:
  • STEPTOE, Andrew
  • KIVIMÄKI, Mika
subjects:
  • Adult
  • Animals
  • Arterial hypertension. Arterial hypotension
  • Biological and medical sciences
  • Blood and lymphatic vessels
  • Cardiology. Vascular system
  • Cardiovascular diseases
  • Cardiovascular Diseases - etiology
  • Coronary Disease - etiology
  • Coronary heart disease
  • Diagnosis
  • Health aspects
  • Heart
  • Humans
  • Hypertension - etiology
  • Medical sciences
  • Myocardial Infarction - etiology
  • Physiological aspects
  • Social isolation
  • Stress (Psychology)
  • Stress, Psychological - complications
ispartof: Annual review of public health, 2013, Vol.34 (1), p.337-354
description: Considerable progress has been made during the past decade in research on cardiovascular effects of stress. Early-life stressors, such as childhood abuse and early socioeconomic adversity, are linked to increased cardiovascular morbidity in adulthood. Our updated meta-analyses of prospective studies published until 2011 show a 1.5-fold (95% confidence interval 1.2-1.9) increased risk of coronary heart disease among adults experiencing social isolation and a 1.3-fold (1.2-1.5) excess risk for workplace stress; adverse metabolic changes are one of the underlying plausible mechanisms. Stress, anger, and depressed mood can act as acute triggers of major cardiac events; the pooled relative risk of acute coronary syndrome onset being preceded by stress is 2.5 (1.8-3.5) in case-crossover studies. Stress is also implicated in the prognosis of cardiovascular disease and in the development of stress (takotsubo) cardiomyopathy. A major challenge over the next decade is to incorporate stress processes into the mainstream of cardiovascular pathophysiological research and understanding.
language: eng
source:
identifier: ISSN: 0163-7525
fulltext: no_fulltext
issn:
  • 0163-7525
  • 1545-2093
url: Link


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descriptionConsiderable progress has been made during the past decade in research on cardiovascular effects of stress. Early-life stressors, such as childhood abuse and early socioeconomic adversity, are linked to increased cardiovascular morbidity in adulthood. Our updated meta-analyses of prospective studies published until 2011 show a 1.5-fold (95% confidence interval 1.2-1.9) increased risk of coronary heart disease among adults experiencing social isolation and a 1.3-fold (1.2-1.5) excess risk for workplace stress; adverse metabolic changes are one of the underlying plausible mechanisms. Stress, anger, and depressed mood can act as acute triggers of major cardiac events; the pooled relative risk of acute coronary syndrome onset being preceded by stress is 2.5 (1.8-3.5) in case-crossover studies. Stress is also implicated in the prognosis of cardiovascular disease and in the development of stress (takotsubo) cardiomyopathy. A major challenge over the next decade is to incorporate stress processes into the mainstream of cardiovascular pathophysiological research and understanding.
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subjectAdult ; Animals ; Arterial hypertension. Arterial hypotension ; Biological and medical sciences ; Blood and lymphatic vessels ; Cardiology. Vascular system ; Cardiovascular diseases ; Cardiovascular Diseases - etiology ; Coronary Disease - etiology ; Coronary heart disease ; Diagnosis ; Health aspects ; Heart ; Humans ; Hypertension - etiology ; Medical sciences ; Myocardial Infarction - etiology ; Physiological aspects ; Social isolation ; Stress (Psychology) ; Stress, Psychological - complications
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abstractConsiderable progress has been made during the past decade in research on cardiovascular effects of stress. Early-life stressors, such as childhood abuse and early socioeconomic adversity, are linked to increased cardiovascular morbidity in adulthood. Our updated meta-analyses of prospective studies published until 2011 show a 1.5-fold (95% confidence interval 1.2-1.9) increased risk of coronary heart disease among adults experiencing social isolation and a 1.3-fold (1.2-1.5) excess risk for workplace stress; adverse metabolic changes are one of the underlying plausible mechanisms. Stress, anger, and depressed mood can act as acute triggers of major cardiac events; the pooled relative risk of acute coronary syndrome onset being preceded by stress is 2.5 (1.8-3.5) in case-crossover studies. Stress is also implicated in the prognosis of cardiovascular disease and in the development of stress (takotsubo) cardiomyopathy. A major challenge over the next decade is to incorporate stress processes into the mainstream of cardiovascular pathophysiological research and understanding.
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