schliessen

Filtern

 

Bibliotheken

Contact with animals and risk of oesophageal squamous cell carcinoma: outcome of a case–control study from Kashmir, a high-risk region

Background Several studies have reported association between animal contact and some cancer types, including lymphohaematopoietic, colon, pancreatic and neurological malignancies. We aimed to investigate the association between animal contact and risk of oesophageal squamous cell carcinoma (ESCC) in... Full description

Journal Title: Occup Environ Med 2014-03, Vol.71 (3), p.208-214
Main Author: Dar, Nazir Ahmad
Other Authors: Islami, Farhad , Bhat, Gulzar Ahmad , Shah, Idrees Ayoub , Makhdoomi, Muzamil Ashraf , Iqbal, Beenish , Rafiq, Rumaisa , Lone, Mohd Maqbool , Boffetta, Paolo
Format: Electronic Article Electronic Article
Language: English
Subjects:
Quelle: Alma/SFX Local Collection
Publisher: London: BMJ Publishing Group
ID: ISSN: 1351-0711
Zum Text:
SendSend as email Add to Book BagAdd to Book Bag
Staff View
recordid: cdi_proquest_miscellaneous_1499123412
title: Contact with animals and risk of oesophageal squamous cell carcinoma: outcome of a case–control study from Kashmir, a high-risk region
format: Article
creator:
  • Dar, Nazir Ahmad
  • Islami, Farhad
  • Bhat, Gulzar Ahmad
  • Shah, Idrees Ayoub
  • Makhdoomi, Muzamil Ashraf
  • Iqbal, Beenish
  • Rafiq, Rumaisa
  • Lone, Mohd Maqbool
  • Boffetta, Paolo
subjects:
  • adverse effects Esophageal Neoplasms
  • adverse effects Occupations Risk Factors Social Class Surveys
  • Aged
  • Aged Animal Husb
  • Alcohol
  • animal contact
  • Animal Husbandry
  • Animals
  • Biological and medical sciences
  • Cancer
  • Carcinoma, Squamous Cell - etiology
  • Case control studies
  • colon
  • Contact potentials
  • Control Studies Environmental Exposure
  • Education
  • Environment
  • Environmental Exposure - adverse effects
  • Esophageal Neoplasms - etiology
  • Esophageal Squamous Cell Carcinoma
  • Esophagus
  • etiology Case
  • etiology Female Humans India Interviews as Topic Livestock Logistic Models Male Middle Aged Occupational Diseases
  • etiology Occupational Exposure
  • Farming
  • Female
  • Formal education
  • Gastroenterology. Liver. Pancreas. Abdomen
  • Health aspects
  • Humans
  • India
  • Interviews as Topic
  • Life Sciences
  • Livestock
  • Logistic Models
  • lymphohaematopoietic
  • Male
  • Medical sciences
  • Middle Aged
  • Multiple tumors. Solid tumors. Tumors in childhood (general aspects)
  • neurological malignancies
  • Occupational Diseases - etiology
  • Occupational Exposure - adverse effects
  • Occupations
  • oesophageal squamous cell carcinoma (ESCC
  • pancreatic
  • Patient outcomes
  • Pesticides
  • Place of residence
  • Population
  • Questionnaires Time Factors
  • Referents
  • Regression analysis
  • Risk Factors
  • Rural areas
  • ry Animals Carcinoma
  • Santé publique et épidémiologie
  • Social Class
  • Socioeconomic factors
  • Socioeconomic status
  • Squamous Cell
  • Squamous cell carcinoma
  • Studies
  • Surveys and Questionnaires
  • Time Factors
  • Tobacco
  • Tumors
  • Usage
  • Wildlife population studies
ispartof: Occup Environ Med, 2014-03, Vol.71 (3), p.208-214
description: Background Several studies have reported association between animal contact and some cancer types, including lymphohaematopoietic, colon, pancreatic and neurological malignancies. We aimed to investigate the association between animal contact and risk of oesophageal squamous cell carcinoma (ESCC) in a case–control study in Kashmir, India, area with a relatively high incidence of ESCC. Methods We recruited 703 histologically confirmed ESCC cases and 1664 controls individually matched to the cases for age, sex and district of residence. Information, including on animal contact, was obtained in face-to-face interviews using a structured questionnaire. Conditional logistic regression models were used to calculate ORs and 95% CIs. Results As compared with no contact with animals, daily close contact was associated with an increased risk of ESCC (OR 5.99; 95% CI 3.86 to 9.31) in models adjusted for several potential confounding factors, including multiple indicators of socioeconomic status. This association persisted in subgroups following stratification by a composite wealth score and occupation. Irregular contact with animals was not associated with ESCC risk. The association between duration of animal contact and ESCC risk was mixed; however, contact for more than 50 years was associated with an increased risk (OR 3.10; 95% CI 1.53 to 6.26). Frequency (p for trend, 0.001) and duration (p for trend,
language: eng
source: Alma/SFX Local Collection
identifier: ISSN: 1351-0711
fulltext: fulltext
issn:
  • 1351-0711
  • 1470-7926
url: Link


@attributes
NO1
SEARCH_ENGINEprimo_central_multiple_fe
SEARCH_ENGINE_TYPEPrimo Central Search Engine
RANK2.3988695
LOCALfalse
PrimoNMBib
record
control
sourceidgale_opena
recordidTN_cdi_proquest_miscellaneous_1499123412
sourceformatXML
sourcesystemPC
galeidA366419203
jstor_id43869841
sourcerecordidA366419203
originalsourceidFETCH-LOGICAL-b580t-9a41b47900465af3ccf5e533b03d2d53e5f658f28efc8f486fe9f7124a323d893
addsrcrecordideNqNks1u1DAUhSMEomXgAViAIlVIIDXFf4kddlUFFFHBBtbWHed6xkMST-2EqjuW7HlDngSn6Y9aIYSiyNH1d861b06WPaXkgFJevfbYYVMwQnlBCVWE3ct2qZCkkDWr7qdvXtKCSEp3skcxbkgCJWcPsx0mBKk4Y7vZzyPfD2CG_MwN6xx610Eb09rkwcVvube5x-i3a1ghtHk8HaHzY8wNtm1uIBjX-w7e5H4cjO9w4iHVI_7-8csk5-CTaBib89wG3-UfIa47F_YTtHardXHRI-DK-f5x9sCm1vjkcl1kX9-9_XJ0XJx8fv_h6PCkWJaKDEUNgi6FrAkRVQmWG2NLLDlfEt6wpuRY2qpUlim0RlmhKou1lZQJ4Iw3quaL7NPs67fYgwuotyFdOpxrD043PQ66wWbc6jOr08C0gIoqgQqplVZKLoTiwFJLuVRlg1UyfDUbrqG95XV8eKKnGqGsYmXJvtPEvpzZbfCnI8ZBdy5Os4Qe01g1FXVNGRfpXWR7d9CNH0OfRqOpVJRTzkh5Q62gRe1664cAZjLVh7yqBK0Z4Yk6-AuVngY7l34TWpfqtwR0FpjgYwxory9GiZ6ipy-ip6fo6Tl6SfP88sDjctq7UlxlLQEvLgGIBloboDcu3nCKSlkrkTh5p7lxAwxuihO49p9HeDYrN3Hw4dpZcFUl42n8-_P-stv8x43-AJS5CV4
sourcetypeOpen Access Repository
isCDItrue
recordtypearticle
pqid1781313205
display
typearticle
titleContact with animals and risk of oesophageal squamous cell carcinoma: outcome of a case–control study from Kashmir, a high-risk region
sourceAlma/SFX Local Collection
creatorDar, Nazir Ahmad ; Islami, Farhad ; Bhat, Gulzar Ahmad ; Shah, Idrees Ayoub ; Makhdoomi, Muzamil Ashraf ; Iqbal, Beenish ; Rafiq, Rumaisa ; Lone, Mohd Maqbool ; Boffetta, Paolo
creatorcontribDar, Nazir Ahmad ; Islami, Farhad ; Bhat, Gulzar Ahmad ; Shah, Idrees Ayoub ; Makhdoomi, Muzamil Ashraf ; Iqbal, Beenish ; Rafiq, Rumaisa ; Lone, Mohd Maqbool ; Boffetta, Paolo
descriptionBackground Several studies have reported association between animal contact and some cancer types, including lymphohaematopoietic, colon, pancreatic and neurological malignancies. We aimed to investigate the association between animal contact and risk of oesophageal squamous cell carcinoma (ESCC) in a case–control study in Kashmir, India, area with a relatively high incidence of ESCC. Methods We recruited 703 histologically confirmed ESCC cases and 1664 controls individually matched to the cases for age, sex and district of residence. Information, including on animal contact, was obtained in face-to-face interviews using a structured questionnaire. Conditional logistic regression models were used to calculate ORs and 95% CIs. Results As compared with no contact with animals, daily close contact was associated with an increased risk of ESCC (OR 5.99; 95% CI 3.86 to 9.31) in models adjusted for several potential confounding factors, including multiple indicators of socioeconomic status. This association persisted in subgroups following stratification by a composite wealth score and occupation. Irregular contact with animals was not associated with ESCC risk. The association between duration of animal contact and ESCC risk was mixed; however, contact for more than 50 years was associated with an increased risk (OR 3.10; 95% CI 1.53 to 6.26). Frequency (p for trend, 0.001) and duration (p for trend, <0.001) of animal contact showed dose–response association with ESCC risk. Conclusions Our results suggest an association between long-term and daily close contact with animals and ESCC. This association needs to be investigated in further studies.
identifier
0ISSN: 1351-0711
1EISSN: 1470-7926
2DOI: 10.1136/oemed-2013-101802
3PMID: 24406322
languageeng
publisherLondon: BMJ Publishing Group
subjectadverse effects Esophageal Neoplasms ; adverse effects Occupations Risk Factors Social Class Surveys ; Aged ; Aged Animal Husb ; Alcohol ; animal contact ; Animal Husbandry ; Animals ; Biological and medical sciences ; Cancer ; Carcinoma, Squamous Cell - etiology ; Case control studies ; colon ; Contact potentials ; Control Studies Environmental Exposure ; Education ; Environment ; Environmental Exposure - adverse effects ; Esophageal Neoplasms - etiology ; Esophageal Squamous Cell Carcinoma ; Esophagus ; etiology Case ; etiology Female Humans India Interviews as Topic Livestock Logistic Models Male Middle Aged Occupational Diseases ; etiology Occupational Exposure ; Farming ; Female ; Formal education ; Gastroenterology. Liver. Pancreas. Abdomen ; Health aspects ; Humans ; India ; Interviews as Topic ; Life Sciences ; Livestock ; Logistic Models ; lymphohaematopoietic ; Male ; Medical sciences ; Middle Aged ; Multiple tumors. Solid tumors. Tumors in childhood (general aspects) ; neurological malignancies ; Occupational Diseases - etiology ; Occupational Exposure - adverse effects ; Occupations ; oesophageal squamous cell carcinoma (ESCC ; pancreatic ; Patient outcomes ; Pesticides ; Place of residence ; Population ; Questionnaires Time Factors ; Referents ; Regression analysis ; Risk Factors ; Rural areas ; ry Animals Carcinoma ; Santé publique et épidémiologie ; Social Class ; Socioeconomic factors ; Socioeconomic status ; Squamous Cell ; Squamous cell carcinoma ; Studies ; Surveys and Questionnaires ; Time Factors ; Tobacco ; Tumors ; Usage ; Wildlife population studies
ispartofOccup Environ Med, 2014-03, Vol.71 (3), p.208-214
rights
0Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions
12014 BMJ Publishing Group
22015 INIST-CNRS
3Copyright: 2014 Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions
4Distributed under a Creative Commons Attribution 4.0 International License
lds50peer_reviewed
oafree_for_read
citedbyFETCH-LOGICAL-b580t-9a41b47900465af3ccf5e533b03d2d53e5f658f28efc8f486fe9f7124a323d893
citesFETCH-LOGICAL-b580t-9a41b47900465af3ccf5e533b03d2d53e5f658f28efc8f486fe9f7124a323d893
links
openurl$$Topenurl_article
openurlfulltext$$Topenurlfull_article
thumbnail$$Usyndetics_thumb_exl
backlink
0$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=28177984$$DView record in Pascal Francis
1$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24406322$$D View this record in MEDLINE/PubMed
2$$Uhttps://hal.archives-ouvertes.fr/hal-01262552$$DView record in HAL
search
creatorcontrib
0Dar, Nazir Ahmad
1Islami, Farhad
2Bhat, Gulzar Ahmad
3Shah, Idrees Ayoub
4Makhdoomi, Muzamil Ashraf
5Iqbal, Beenish
6Rafiq, Rumaisa
7Lone, Mohd Maqbool
8Boffetta, Paolo
title
0Contact with animals and risk of oesophageal squamous cell carcinoma: outcome of a case–control study from Kashmir, a high-risk region
1Occup Environ Med
addtitleOccup Environ Med
descriptionBackground Several studies have reported association between animal contact and some cancer types, including lymphohaematopoietic, colon, pancreatic and neurological malignancies. We aimed to investigate the association between animal contact and risk of oesophageal squamous cell carcinoma (ESCC) in a case–control study in Kashmir, India, area with a relatively high incidence of ESCC. Methods We recruited 703 histologically confirmed ESCC cases and 1664 controls individually matched to the cases for age, sex and district of residence. Information, including on animal contact, was obtained in face-to-face interviews using a structured questionnaire. Conditional logistic regression models were used to calculate ORs and 95% CIs. Results As compared with no contact with animals, daily close contact was associated with an increased risk of ESCC (OR 5.99; 95% CI 3.86 to 9.31) in models adjusted for several potential confounding factors, including multiple indicators of socioeconomic status. This association persisted in subgroups following stratification by a composite wealth score and occupation. Irregular contact with animals was not associated with ESCC risk. The association between duration of animal contact and ESCC risk was mixed; however, contact for more than 50 years was associated with an increased risk (OR 3.10; 95% CI 1.53 to 6.26). Frequency (p for trend, 0.001) and duration (p for trend, <0.001) of animal contact showed dose–response association with ESCC risk. Conclusions Our results suggest an association between long-term and daily close contact with animals and ESCC. This association needs to be investigated in further studies.
subject
0adverse effects Esophageal Neoplasms
1adverse effects Occupations Risk Factors Social Class Surveys
2Aged
3Aged Animal Husb
4Alcohol
5animal contact
6Animal Husbandry
7Animals
8Biological and medical sciences
9Cancer
10Carcinoma, Squamous Cell - etiology
11Case control studies
12colon
13Contact potentials
14Control Studies Environmental Exposure
15Education
16Environment
17Environmental Exposure - adverse effects
18Esophageal Neoplasms - etiology
19Esophageal Squamous Cell Carcinoma
20Esophagus
21etiology Case
22etiology Female Humans India Interviews as Topic Livestock Logistic Models Male Middle Aged Occupational Diseases
23etiology Occupational Exposure
24Farming
25Female
26Formal education
27Gastroenterology. Liver. Pancreas. Abdomen
28Health aspects
29Humans
30India
31Interviews as Topic
32Life Sciences
33Livestock
34Logistic Models
35lymphohaematopoietic
36Male
37Medical sciences
38Middle Aged
39Multiple tumors. Solid tumors. Tumors in childhood (general aspects)
40neurological malignancies
41Occupational Diseases - etiology
42Occupational Exposure - adverse effects
43Occupations
44oesophageal squamous cell carcinoma (ESCC
45pancreatic
46Patient outcomes
47Pesticides
48Place of residence
49Population
50Questionnaires Time Factors
51Referents
52Regression analysis
53Risk Factors
54Rural areas
55ry Animals Carcinoma
56Santé publique et épidémiologie
57Social Class
58Socioeconomic factors
59Socioeconomic status
60Squamous Cell
61Squamous cell carcinoma
62Studies
63Surveys and Questionnaires
64Time Factors
65Tobacco
66Tumors
67Usage
68Wildlife population studies
issn
01351-0711
11470-7926
fulltexttrue
rsrctypearticle
creationdate2014
recordtypearticle
recordideNqNks1u1DAUhSMEomXgAViAIlVIIDXFf4kddlUFFFHBBtbWHed6xkMST-2EqjuW7HlDngSn6Y9aIYSiyNH1d861b06WPaXkgFJevfbYYVMwQnlBCVWE3ct2qZCkkDWr7qdvXtKCSEp3skcxbkgCJWcPsx0mBKk4Y7vZzyPfD2CG_MwN6xx610Eb09rkwcVvube5x-i3a1ghtHk8HaHzY8wNtm1uIBjX-w7e5H4cjO9w4iHVI_7-8csk5-CTaBib89wG3-UfIa47F_YTtHardXHRI-DK-f5x9sCm1vjkcl1kX9-9_XJ0XJx8fv_h6PCkWJaKDEUNgi6FrAkRVQmWG2NLLDlfEt6wpuRY2qpUlim0RlmhKou1lZQJ4Iw3quaL7NPs67fYgwuotyFdOpxrD043PQ66wWbc6jOr08C0gIoqgQqplVZKLoTiwFJLuVRlg1UyfDUbrqG95XV8eKKnGqGsYmXJvtPEvpzZbfCnI8ZBdy5Os4Qe01g1FXVNGRfpXWR7d9CNH0OfRqOpVJRTzkh5Q62gRe1664cAZjLVh7yqBK0Z4Yk6-AuVngY7l34TWpfqtwR0FpjgYwxory9GiZ6ipy-ip6fo6Tl6SfP88sDjctq7UlxlLQEvLgGIBloboDcu3nCKSlkrkTh5p7lxAwxuihO49p9HeDYrN3Hw4dpZcFUl42n8-_P-stv8x43-AJS5CV4
startdate201403
enddate201403
creator
0Dar, Nazir Ahmad
1Islami, Farhad
2Bhat, Gulzar Ahmad
3Shah, Idrees Ayoub
4Makhdoomi, Muzamil Ashraf
5Iqbal, Beenish
6Rafiq, Rumaisa
7Lone, Mohd Maqbool
8Boffetta, Paolo
general
0BMJ Publishing Group
1BMJ Publishing Group Ltd
2BMJ Publishing Group LTD
3HAL CCSD
scope
0IQODW
1CGR
2CUY
3CVF
4ECM
5EIF
6NPM
7AAYXX
8CITATION
9BSHEE
103V.
117RV
127X7
137XB
1488E
158C1
168FE
178FG
188FI
198FJ
208FK
21ABJCF
22ABUWG
23ATCPS
24AZQEC
25BENPR
26BGLVJ
27BHPHI
28BTHHO
29DWQXO
30FYUFA
31GHDGH
32GNUQQ
33HCIFZ
34K9.
35KB0
36L6V
37M0S
38M1P
39M7S
40NAPCQ
41PATMY
42PQEST
43PQQKQ
44PQUKI
45PRINS
46PTHSS
47PYCSY
487X8
491XC
50BOBZL
51CLFQK
sort
creationdate201403
titleContact with animals and risk of oesophageal squamous cell carcinoma: outcome of a case–control study from Kashmir, a high-risk region
authorDar, Nazir Ahmad ; Islami, Farhad ; Bhat, Gulzar Ahmad ; Shah, Idrees Ayoub ; Makhdoomi, Muzamil Ashraf ; Iqbal, Beenish ; Rafiq, Rumaisa ; Lone, Mohd Maqbool ; Boffetta, Paolo
facets
frbrtype5
frbrgroupidcdi_FETCH-LOGICAL-b580t-9a41b47900465af3ccf5e533b03d2d53e5f658f28efc8f486fe9f7124a323d893
rsrctypearticles
prefilterarticles
languageeng
creationdate2014
topic
0adverse effects Esophageal Neoplasms
1adverse effects Occupations Risk Factors Social Class Surveys
2Aged
3Aged Animal Husb
4Alcohol
5animal contact
6Animal Husbandry
7Animals
8Biological and medical sciences
9Cancer
10Carcinoma, Squamous Cell - etiology
11Case control studies
12colon
13Contact potentials
14Control Studies Environmental Exposure
15Education
16Environment
17Environmental Exposure - adverse effects
18Esophageal Neoplasms - etiology
19Esophageal Squamous Cell Carcinoma
20Esophagus
21etiology Case
22etiology Female Humans India Interviews as Topic Livestock Logistic Models Male Middle Aged Occupational Diseases
23etiology Occupational Exposure
24Farming
25Female
26Formal education
27Gastroenterology. Liver. Pancreas. Abdomen
28Health aspects
29Humans
30India
31Interviews as Topic
32Life Sciences
33Livestock
34Logistic Models
35lymphohaematopoietic
36Male
37Medical sciences
38Middle Aged
39Multiple tumors. Solid tumors. Tumors in childhood (general aspects)
40neurological malignancies
41Occupational Diseases - etiology
42Occupational Exposure - adverse effects
43Occupations
44oesophageal squamous cell carcinoma (ESCC
45pancreatic
46Patient outcomes
47Pesticides
48Place of residence
49Population
50Questionnaires Time Factors
51Referents
52Regression analysis
53Risk Factors
54Rural areas
55ry Animals Carcinoma
56Santé publique et épidémiologie
57Social Class
58Socioeconomic factors
59Socioeconomic status
60Squamous Cell
61Squamous cell carcinoma
62Studies
63Surveys and Questionnaires
64Time Factors
65Tobacco
66Tumors
67Usage
68Wildlife population studies
toplevel
0peer_reviewed
1online_resources
creatorcontrib
0Dar, Nazir Ahmad
1Islami, Farhad
2Bhat, Gulzar Ahmad
3Shah, Idrees Ayoub
4Makhdoomi, Muzamil Ashraf
5Iqbal, Beenish
6Rafiq, Rumaisa
7Lone, Mohd Maqbool
8Boffetta, Paolo
collection
0Pascal-Francis
1Medline
2MEDLINE
3MEDLINE (Ovid)
4MEDLINE
5MEDLINE
6PubMed
7CrossRef
8Academic OneFile (A&I only)
9ProQuest Central (Corporate)
10Nursing & Allied Health Database
11Health & Medical Collection
12ProQuest Central (purchase pre-March 2016)
13Medical Database (Alumni Edition)
14Public Health Database
15ProQuest SciTech Collection
16ProQuest Technology Collection
17Hospital Premium Collection
18Hospital Premium Collection (Alumni Edition)
19ProQuest Central (Alumni) (purchase pre-March 2016)
20Materials Science & Engineering Collection
21ProQuest Central (Alumni Edition)
22Agricultural & Environmental Science Collection
23ProQuest Central Essentials
24ProQuest Central
25Technology Collection
26Natural Science Collection
27BMJ Journals
28ProQuest Central Korea
29Health Research Premium Collection
30Health Research Premium Collection (Alumni)
31ProQuest Central Student
32SciTech Premium Collection
33ProQuest Health & Medical Complete (Alumni)
34Nursing & Allied Health Database (Alumni Edition)
35ProQuest Engineering Collection
36Health & Medical Collection (Alumni Edition)
37Medical Database
38Engineering Database
39Nursing & Allied Health Premium
40Environmental Science Database
41ProQuest One Academic Eastern Edition
42ProQuest One Academic
43ProQuest One Academic UKI Edition
44ProQuest Central China
45Engineering Collection
46Environmental Science Collection
47MEDLINE - Academic
48Hyper Article en Ligne (HAL)
49OpenAIRE (Open Access)
50OpenAIRE
jtitleOccup Environ Med
delivery
delcategoryRemote Search Resource
fulltextfulltext
addata
au
0Dar, Nazir Ahmad
1Islami, Farhad
2Bhat, Gulzar Ahmad
3Shah, Idrees Ayoub
4Makhdoomi, Muzamil Ashraf
5Iqbal, Beenish
6Rafiq, Rumaisa
7Lone, Mohd Maqbool
8Boffetta, Paolo
formatjournal
genrearticle
ristypeJOUR
atitleContact with animals and risk of oesophageal squamous cell carcinoma: outcome of a case–control study from Kashmir, a high-risk region
jtitleOccup Environ Med
addtitleOccup Environ Med
date2014-03
risdate2014
volume71
issue3
spage208
epage214
pages208-214
issn1351-0711
eissn1470-7926
abstractBackground Several studies have reported association between animal contact and some cancer types, including lymphohaematopoietic, colon, pancreatic and neurological malignancies. We aimed to investigate the association between animal contact and risk of oesophageal squamous cell carcinoma (ESCC) in a case–control study in Kashmir, India, area with a relatively high incidence of ESCC. Methods We recruited 703 histologically confirmed ESCC cases and 1664 controls individually matched to the cases for age, sex and district of residence. Information, including on animal contact, was obtained in face-to-face interviews using a structured questionnaire. Conditional logistic regression models were used to calculate ORs and 95% CIs. Results As compared with no contact with animals, daily close contact was associated with an increased risk of ESCC (OR 5.99; 95% CI 3.86 to 9.31) in models adjusted for several potential confounding factors, including multiple indicators of socioeconomic status. This association persisted in subgroups following stratification by a composite wealth score and occupation. Irregular contact with animals was not associated with ESCC risk. The association between duration of animal contact and ESCC risk was mixed; however, contact for more than 50 years was associated with an increased risk (OR 3.10; 95% CI 1.53 to 6.26). Frequency (p for trend, 0.001) and duration (p for trend, <0.001) of animal contact showed dose–response association with ESCC risk. Conclusions Our results suggest an association between long-term and daily close contact with animals and ESCC. This association needs to be investigated in further studies.
copLondon
pubBMJ Publishing Group
pmid24406322
doi10.1136/oemed-2013-101802
oafree_for_read