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Allergen-specific IgE is not detectable in the bronchial mucosa of nonatopic asthmatic patients

Byline: Prathap Pillai, Cailong Fang, Yih-Chih Chan, Mohamed H. Shamji, Clare Harper, Shih-Ying Wu, Line Ohm-Laursen, Stephen R. Durham, Andrew Menzies-Gow, Raj K. Rajakulasingam, Sun Ying, Chris J. Corrigan, Hannah J. Gould Author Affiliation: (a) Department of Asthma, Allergy and Respiratory Scien... Full description

Journal Title: Journal of allergy and clinical immunology 2014, Vol.133 (6), p.1770-1772.e11
Main Author: Pillai, Prathap, MD
Other Authors: Fang, Cailong, PhD , Chan, Yih-Chih, PhD , Shamji, Mohamed H., PhD , Harper, Clare, PhD , Wu, Shih-Ying, MSc , Ohm-Laursen, Line, PhD , Durham, Stephen R., MD, FRCP , Menzies-Gow, Andrew, MD , Rajakulasingam, Raj K., MD , Ying, Sun, PhD , Corrigan, Chris J., PhD , Gould, Hannah J., PhD
Format: Electronic Article Electronic Article
Language: English
Subjects:
Quelle: Alma/SFX Local Collection
Publisher: United States: Elsevier Inc
ID: ISSN: 0091-6749
Link: https://www.ncbi.nlm.nih.gov/pubmed/24794682
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title: Allergen-specific IgE is not detectable in the bronchial mucosa of nonatopic asthmatic patients
format: Article
creator:
  • Pillai, Prathap, MD
  • Fang, Cailong, PhD
  • Chan, Yih-Chih, PhD
  • Shamji, Mohamed H., PhD
  • Harper, Clare, PhD
  • Wu, Shih-Ying, MSc
  • Ohm-Laursen, Line, PhD
  • Durham, Stephen R., MD, FRCP
  • Menzies-Gow, Andrew, MD
  • Rajakulasingam, Raj K., MD
  • Ying, Sun, PhD
  • Corrigan, Chris J., PhD
  • Gould, Hannah J., PhD
subjects:
  • Allergens
  • Allergens - immunology
  • Allergies
  • Allergy and Immunology
  • Antibody Specificity
  • Asthma
  • Asthma - diagnosis
  • Asthma - immunology
  • Biopsy
  • Bronchi - immunology
  • Humans
  • Hypotheses
  • Immunoglobulin E
  • Immunoglobulin E - immunology
  • Mucous membrane
  • Patients
  • Respiratory Mucosa - immunology
  • Rodents
ispartof: Journal of allergy and clinical immunology, 2014, Vol.133 (6), p.1770-1772.e11
description: Byline: Prathap Pillai, Cailong Fang, Yih-Chih Chan, Mohamed H. Shamji, Clare Harper, Shih-Ying Wu, Line Ohm-Laursen, Stephen R. Durham, Andrew Menzies-Gow, Raj K. Rajakulasingam, Sun Ying, Chris J. Corrigan, Hannah J. Gould Author Affiliation: (a) Department of Asthma, Allergy and Respiratory Science and Randall Division of Cell and Molecular Biophysics, King's College London, London (b) Section for Allergy and Clinical Immunology at NHLI, Imperial College, London (c) Department of Respiratory Medicine and Allergy, Homerton University Hospital NHS Foundation Trust, London, United Kingdom Article History: Received 17 June 2013; Revised 23 February 2014; Accepted 25 March 2014 Article Note: (footnote) Supported by research grants from the Wellcome Trust UK (no. 091449/Z/10/Z), Novartis UK, and Guy's and St Thomas' Charity. Also supported by the Department of Health via the National Institute for Health Research (NIHR) comprehensive Biomedical Research Centre award to Guy's & St Thomas' NHS Foundation Trust in partnership with King's College London and King's College Hospital NHS Foundation Trust., Disclosure of potential conflict of interest: C. Harper has received research support from Novartis. L. Ohm-Laursen has received research support from the Wellcome Trust. A. Menzies-Gow has received lecture fees and travel support from Novartis. C. J. Corrigan has received consultancy fees from Chiesi, Novartis, and Allergy Therapeutics; has received lecture fees from GlaxoSmithKline; has received payment for development of educational presentations from Henry Stewart Talks; and has received travel support from Novartis. The rest of the authors declare that they have no relevant conflicts of interest.
language: eng
source: Alma/SFX Local Collection
identifier: ISSN: 0091-6749
fulltext: fulltext
issn:
  • 0091-6749
  • 1097-6825
url: Link


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titleAllergen-specific IgE is not detectable in the bronchial mucosa of nonatopic asthmatic patients
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subjectAllergens ; Allergens - immunology ; Allergies ; Allergy and Immunology ; Antibody Specificity ; Asthma ; Asthma - diagnosis ; Asthma - immunology ; Biopsy ; Bronchi - immunology ; Humans ; Hypotheses ; Immunoglobulin E ; Immunoglobulin E - immunology ; Mucous membrane ; Patients ; Respiratory Mucosa - immunology ; Rodents
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titleAllergen-specific IgE is not detectable in the bronchial mucosa of nonatopic asthmatic patients
authorPillai, Prathap, MD ; Fang, Cailong, PhD ; Chan, Yih-Chih, PhD ; Shamji, Mohamed H., PhD ; Harper, Clare, PhD ; Wu, Shih-Ying, MSc ; Ohm-Laursen, Line, PhD ; Durham, Stephen R., MD, FRCP ; Menzies-Gow, Andrew, MD ; Rajakulasingam, Raj K., MD ; Ying, Sun, PhD ; Corrigan, Chris J., PhD ; Gould, Hannah J., PhD
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abstractByline: Prathap Pillai, Cailong Fang, Yih-Chih Chan, Mohamed H. Shamji, Clare Harper, Shih-Ying Wu, Line Ohm-Laursen, Stephen R. Durham, Andrew Menzies-Gow, Raj K. Rajakulasingam, Sun Ying, Chris J. Corrigan, Hannah J. Gould Author Affiliation: (a) Department of Asthma, Allergy and Respiratory Science and Randall Division of Cell and Molecular Biophysics, King's College London, London (b) Section for Allergy and Clinical Immunology at NHLI, Imperial College, London (c) Department of Respiratory Medicine and Allergy, Homerton University Hospital NHS Foundation Trust, London, United Kingdom Article History: Received 17 June 2013; Revised 23 February 2014; Accepted 25 March 2014 Article Note: (footnote) Supported by research grants from the Wellcome Trust UK (no. 091449/Z/10/Z), Novartis UK, and Guy's and St Thomas' Charity. Also supported by the Department of Health via the National Institute for Health Research (NIHR) comprehensive Biomedical Research Centre award to Guy's & St Thomas' NHS Foundation Trust in partnership with King's College London and King's College Hospital NHS Foundation Trust., Disclosure of potential conflict of interest: C. Harper has received research support from Novartis. L. Ohm-Laursen has received research support from the Wellcome Trust. A. Menzies-Gow has received lecture fees and travel support from Novartis. C. J. Corrigan has received consultancy fees from Chiesi, Novartis, and Allergy Therapeutics; has received lecture fees from GlaxoSmithKline; has received payment for development of educational presentations from Henry Stewart Talks; and has received travel support from Novartis. The rest of the authors declare that they have no relevant conflicts of interest.
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pmid24794682
doi10.1016/j.jaci.2014.03.027