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Effects of coffee on type 2 diabetes mellitus

Abstract This review provides the epidemiologic and research evidences documenting the effects of coffee consumption on type 2 diabetes mellitus (T2DM). We summarize the literature concerning the effects of coffee consumption on different mechanistic factors involving in pathogenesis of T2DM, such a... Full description

Journal Title: Nutrition (Burbank Los Angeles County, Calif.), 2014, Vol.30 (7), p.755-763
Main Author: Akash, Muhammad Sajid Hamid, Ph.D
Other Authors: Rehman, Kanwal, B.Pharm., M.Phil , Chen, Shuqing, Ph.D
Format: Electronic Article Electronic Article
Language: English
Subjects:
Quelle: Alma/SFX Local Collection
Publisher: New York, NY: Elsevier Inc
ID: ISSN: 0899-9007
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recordid: cdi_proquest_miscellaneous_1552804056
title: Effects of coffee on type 2 diabetes mellitus
format: Article
creator:
  • Akash, Muhammad Sajid Hamid, Ph.D
  • Rehman, Kanwal, B.Pharm., M.Phil
  • Chen, Shuqing, Ph.D
subjects:
  • Antioxidants
  • Biological and medical sciences
  • Blood Glucose - metabolism
  • Cardiovascular disease
  • Chlorogenic acid
  • Coffea - chemistry
  • Coffee
  • Coffee consumption
  • Dextrose
  • Diabetes mellitus
  • Diabetes Mellitus, Type 2 - drug therapy
  • Diabetes Mellitus, Type 2 - metabolism
  • Diabetes. Impaired glucose tolerance
  • Diabetics
  • Endocrine pancreas. Apud cells (diseases)
  • Endocrinopathies
  • Etiopathogenesis. Screening. Investigations. Target tissue resistance
  • Feeding. Feeding behavior
  • Fundamental and applied biological sciences. Psychology
  • Gastroenterology and Hepatology
  • Glucose
  • Glucose homeostasis
  • Glucose metabolism
  • Humans
  • Hyperglycemia
  • Inflammation - drug therapy
  • Inflammation - metabolism
  • Inflammatory biomarkers
  • Insulin
  • Insulin - metabolism
  • Insulin Resistance
  • Insulin sensitivity
  • Medical sciences
  • Oxidative Stress - drug effects
  • Phytotherapy
  • Studies
  • Type 2 diabetes
  • Vertebrates: anatomy and physiology, studies on body, several organs or systems
ispartof: Nutrition (Burbank, Los Angeles County, Calif.), 2014, Vol.30 (7), p.755-763
description: Abstract This review provides the epidemiologic and research evidences documenting the effects of coffee consumption on type 2 diabetes mellitus (T2DM). We summarize the literature concerning the effects of coffee consumption on different mechanistic factors involving in pathogenesis of T2DM, such as glucose tolerance, insulin sensitivity, insulin resistance, glucose-6-phosphatase, intestinal glucose absorption, antioxidant activity, inflammatory biomarkers, nuclear factor-κB inhibition, glucose uptake, glucose homeostasis, glucose metabolism, and insulin secretion. These factors play a crucial role in influencing the normal levels of glucose in blood. Overall, the experimental and epidemiologic evidences presented here elucidate the protective effects of coffee consumption on T2DM, involving multiple preventive mechanisms. Despite the firm evidences available through a growing literature base, it is still uncertain whether the use of coffee should be recommended to patients with diabetes and/or any patient who might be at the risk of T2DM as a supplementary therapy to prevent further progression of T2DM.
language: eng
source: Alma/SFX Local Collection
identifier: ISSN: 0899-9007
fulltext: fulltext
issn:
  • 0899-9007
  • 1873-1244
url: Link


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descriptionAbstract This review provides the epidemiologic and research evidences documenting the effects of coffee consumption on type 2 diabetes mellitus (T2DM). We summarize the literature concerning the effects of coffee consumption on different mechanistic factors involving in pathogenesis of T2DM, such as glucose tolerance, insulin sensitivity, insulin resistance, glucose-6-phosphatase, intestinal glucose absorption, antioxidant activity, inflammatory biomarkers, nuclear factor-κB inhibition, glucose uptake, glucose homeostasis, glucose metabolism, and insulin secretion. These factors play a crucial role in influencing the normal levels of glucose in blood. Overall, the experimental and epidemiologic evidences presented here elucidate the protective effects of coffee consumption on T2DM, involving multiple preventive mechanisms. Despite the firm evidences available through a growing literature base, it is still uncertain whether the use of coffee should be recommended to patients with diabetes and/or any patient who might be at the risk of T2DM as a supplementary therapy to prevent further progression of T2DM.
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languageeng
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subjectAntioxidants ; Biological and medical sciences ; Blood Glucose - metabolism ; Cardiovascular disease ; Chlorogenic acid ; Coffea - chemistry ; Coffee ; Coffee consumption ; Dextrose ; Diabetes mellitus ; Diabetes Mellitus, Type 2 - drug therapy ; Diabetes Mellitus, Type 2 - metabolism ; Diabetes. Impaired glucose tolerance ; Diabetics ; Endocrine pancreas. Apud cells (diseases) ; Endocrinopathies ; Etiopathogenesis. Screening. Investigations. Target tissue resistance ; Feeding. Feeding behavior ; Fundamental and applied biological sciences. Psychology ; Gastroenterology and Hepatology ; Glucose ; Glucose homeostasis ; Glucose metabolism ; Humans ; Hyperglycemia ; Inflammation - drug therapy ; Inflammation - metabolism ; Inflammatory biomarkers ; Insulin ; Insulin - metabolism ; Insulin Resistance ; Insulin sensitivity ; Medical sciences ; Oxidative Stress - drug effects ; Phytotherapy ; Studies ; Type 2 diabetes ; Vertebrates: anatomy and physiology, studies on body, several organs or systems
ispartofNutrition (Burbank, Los Angeles County, Calif.), 2014, Vol.30 (7), p.755-763
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descriptionAbstract This review provides the epidemiologic and research evidences documenting the effects of coffee consumption on type 2 diabetes mellitus (T2DM). We summarize the literature concerning the effects of coffee consumption on different mechanistic factors involving in pathogenesis of T2DM, such as glucose tolerance, insulin sensitivity, insulin resistance, glucose-6-phosphatase, intestinal glucose absorption, antioxidant activity, inflammatory biomarkers, nuclear factor-κB inhibition, glucose uptake, glucose homeostasis, glucose metabolism, and insulin secretion. These factors play a crucial role in influencing the normal levels of glucose in blood. Overall, the experimental and epidemiologic evidences presented here elucidate the protective effects of coffee consumption on T2DM, involving multiple preventive mechanisms. Despite the firm evidences available through a growing literature base, it is still uncertain whether the use of coffee should be recommended to patients with diabetes and/or any patient who might be at the risk of T2DM as a supplementary therapy to prevent further progression of T2DM.
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4Chlorogenic acid
5Coffea - chemistry
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8Dextrose
9Diabetes mellitus
10Diabetes Mellitus, Type 2 - drug therapy
11Diabetes Mellitus, Type 2 - metabolism
12Diabetes. Impaired glucose tolerance
13Diabetics
14Endocrine pancreas. Apud cells (diseases)
15Endocrinopathies
16Etiopathogenesis. Screening. Investigations. Target tissue resistance
17Feeding. Feeding behavior
18Fundamental and applied biological sciences. Psychology
19Gastroenterology and Hepatology
20Glucose
21Glucose homeostasis
22Glucose metabolism
23Humans
24Hyperglycemia
25Inflammation - drug therapy
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27Inflammatory biomarkers
28Insulin
29Insulin - metabolism
30Insulin Resistance
31Insulin sensitivity
32Medical sciences
33Oxidative Stress - drug effects
34Phytotherapy
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abstractAbstract This review provides the epidemiologic and research evidences documenting the effects of coffee consumption on type 2 diabetes mellitus (T2DM). We summarize the literature concerning the effects of coffee consumption on different mechanistic factors involving in pathogenesis of T2DM, such as glucose tolerance, insulin sensitivity, insulin resistance, glucose-6-phosphatase, intestinal glucose absorption, antioxidant activity, inflammatory biomarkers, nuclear factor-κB inhibition, glucose uptake, glucose homeostasis, glucose metabolism, and insulin secretion. These factors play a crucial role in influencing the normal levels of glucose in blood. Overall, the experimental and epidemiologic evidences presented here elucidate the protective effects of coffee consumption on T2DM, involving multiple preventive mechanisms. Despite the firm evidences available through a growing literature base, it is still uncertain whether the use of coffee should be recommended to patients with diabetes and/or any patient who might be at the risk of T2DM as a supplementary therapy to prevent further progression of T2DM.
copNew York, NY
pubElsevier Inc
pmid24984989
doi10.1016/j.nut.2013.11.020