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Magnitude of blood pressure reduction and clinical outcomes in acute intracerebral hemorrhage: intensive blood pressure reduction in acute cerebral hemorrhage trial study

Evidence supports early intensive blood pressure (BP) lowering in acute intracerebral hemorrhage, but uncertainty persists over whether potential benefits and harms vary according to the magnitude of BP reduction. We aimed to determine whether larger systolic BP (SBP) reductions were associated with... Full description

Journal Title: Hypertension (Dallas Tex. 1979), 2015, Vol.65 (5), p.1026-1032
Main Author: Wang, Xia
Other Authors: Arima, Hisatomi , Heeley, Emma , Delcourt, Candice , Huang, Yining , Wang, Jiguang , Stapf, Christian , Robinson, Thompson , Woodward, Mark , Chalmers, John , Anderson, Craig S
Format: Electronic Article Electronic Article
Language: English
Subjects:
Acute Disease
Administration, Oral
Aged
Antihypertensive Agents - administration & dosage
Blood Pressure - physiology
Cerebral Hemorrhage - drug therapy
Cerebral Hemorrhage - etiology
Cerebral Hemorrhage - physiopathology
Dose-Response Relationship, Drug
Female
Follow-Up Studies
Humans
Hypertension - complications
Hypertension - drug therapy
Hypertension - physiopathology
Injections, Intravenous
Male
Middle Aged
Prognosis
Single-Blind Method
Time Factors
Treatment Outcome
Publisher: United States
ID: ISSN: 0194-911X
Link: https://www.ncbi.nlm.nih.gov/pubmed/25801872
Zum Text:
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recordid: cdi_proquest_miscellaneous_1672612707
title: Magnitude of blood pressure reduction and clinical outcomes in acute intracerebral hemorrhage: intensive blood pressure reduction in acute cerebral hemorrhage trial study
format: Article
creator:
  • Wang, Xia
  • Arima, Hisatomi
  • Heeley, Emma
  • Delcourt, Candice
  • Huang, Yining
  • Wang, Jiguang
  • Stapf, Christian
  • Robinson, Thompson
  • Woodward, Mark
  • Chalmers, John
  • Anderson, Craig S
subjects:
  • Acute Disease
  • Administration, Oral
  • Aged
  • Antihypertensive Agents - administration & dosage
  • Blood Pressure - physiology
  • Cerebral Hemorrhage - drug therapy
  • Cerebral Hemorrhage - etiology
  • Cerebral Hemorrhage - physiopathology
  • Dose-Response Relationship, Drug
  • Female
  • Follow-Up Studies
  • Humans
  • Hypertension - complications
  • Hypertension - drug therapy
  • Hypertension - physiopathology
  • Injections, Intravenous
  • Male
  • Middle Aged
  • Prognosis
  • Single-Blind Method
  • Time Factors
  • Treatment Outcome
ispartof: Hypertension (Dallas, Tex. 1979), 2015, Vol.65 (5), p.1026-1032
description: Evidence supports early intensive blood pressure (BP) lowering in acute intracerebral hemorrhage, but uncertainty persists over whether potential benefits and harms vary according to the magnitude of BP reduction. We aimed to determine whether larger systolic BP (SBP) reductions were associated with better outcomes in participants of the Intensive Blood Pressure Reduction in Acute Cerebral Hemorrhage Trial (INTERACT2). INTERACT2 was an international, open, blinded end point, randomized controlled trial of patients with spontaneous intracerebral hemorrhage (
language: eng
source:
identifier: ISSN: 0194-911X
fulltext: no_fulltext
issn:
  • 0194-911X
  • 1524-4563
url: Link


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titleMagnitude of blood pressure reduction and clinical outcomes in acute intracerebral hemorrhage: intensive blood pressure reduction in acute cerebral hemorrhage trial study
creatorWang, Xia ; Arima, Hisatomi ; Heeley, Emma ; Delcourt, Candice ; Huang, Yining ; Wang, Jiguang ; Stapf, Christian ; Robinson, Thompson ; Woodward, Mark ; Chalmers, John ; Anderson, Craig S
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subjectAcute Disease ; Administration, Oral ; Aged ; Antihypertensive Agents - administration & dosage ; Blood Pressure - physiology ; Cerebral Hemorrhage - drug therapy ; Cerebral Hemorrhage - etiology ; Cerebral Hemorrhage - physiopathology ; Dose-Response Relationship, Drug ; Female ; Follow-Up Studies ; Humans ; Hypertension - complications ; Hypertension - drug therapy ; Hypertension - physiopathology ; Injections, Intravenous ; Male ; Middle Aged ; Prognosis ; Single-Blind Method ; Time Factors ; Treatment Outcome
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