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Characteristics of COPD in never-smokers and ever-smokers in the general population: results from the CanCOLD study

BackgroundThere is limited data on the risk factors and phenotypical characteristics associated with spirometrically confirmed COPD in never-smokers in the general population.AimsTo compare the characteristics associated with COPD by gender and by severity of airway obstruction in never-smokers and... Full description

Journal Title: Thorax 2015-09, Vol.70 (9), p.822-829
Main Author: Tan, W C
Other Authors: Sin, D D , Bourbeau, J , Hernandez, P , Chapman, K R , Cowie, R , FitzGerald, J M , Marciniuk, D D , Maltais, F , Buist, A S , Road, J , Hogg, J C , Kirby, M , Coxson, H , Hague, C , Leipsic, J , O'Donnell, D E , Aaron, S D
Format: Electronic Article Electronic Article
Language: English
Subjects:
Quelle: Alma/SFX Local Collection
Publisher: England: British Medical Association
ID: ISSN: 0040-6376
Link: https://www.ncbi.nlm.nih.gov/pubmed/26048404
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title: Characteristics of COPD in never-smokers and ever-smokers in the general population: results from the CanCOLD study
format: Article
creator:
  • Tan, W C
  • Sin, D D
  • Bourbeau, J
  • Hernandez, P
  • Chapman, K R
  • Cowie, R
  • FitzGerald, J M
  • Marciniuk, D D
  • Maltais, F
  • Buist, A S
  • Road, J
  • Hogg, J C
  • Kirby, M
  • Coxson, H
  • Hague, C
  • Leipsic, J
  • O'Donnell, D E
  • Aaron, S D
subjects:
  • Adult
  • Aged
  • Airway Obstruction - physiopathology
  • Canada
  • Care and treatment
  • Clinical trials
  • Cross-Sectional Studies
  • CT imaging
  • Female
  • Health aspects
  • Hospitalization
  • Humans
  • Logistic Models
  • Lung - physiopathology
  • Lung diseases, Obstructive
  • Male
  • Middle Aged
  • Observational studies
  • Prevalence
  • Prospective Studies
  • Pulmonary Disease, Chronic Obstructive - physiopathology
  • Risk Factors
  • Smokers
  • Smoking - adverse effects
  • Tobacco Smoke Pollution - adverse effects
  • Usage
ispartof: Thorax, 2015-09, Vol.70 (9), p.822-829
description: BackgroundThere is limited data on the risk factors and phenotypical characteristics associated with spirometrically confirmed COPD in never-smokers in the general population.AimsTo compare the characteristics associated with COPD by gender and by severity of airway obstruction in never-smokers and in ever-smokers.MethodWe analysed the data from 5176 adults aged 40 years and older who participated in the initial cross-sectional phase of the population-based, prospective, multisite Canadian Cohort of Obstructive Lung Disease study. Never-smokers were defined as those with a lifetime exposure of
language: eng
source: Alma/SFX Local Collection
identifier: ISSN: 0040-6376
fulltext: fulltext
issn:
  • 0040-6376
  • 1468-3296
url: Link


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titleCharacteristics of COPD in never-smokers and ever-smokers in the general population: results from the CanCOLD study
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creatorTan, W C ; Sin, D D ; Bourbeau, J ; Hernandez, P ; Chapman, K R ; Cowie, R ; FitzGerald, J M ; Marciniuk, D D ; Maltais, F ; Buist, A S ; Road, J ; Hogg, J C ; Kirby, M ; Coxson, H ; Hague, C ; Leipsic, J ; O'Donnell, D E ; Aaron, S D
creatorcontribTan, W C ; Sin, D D ; Bourbeau, J ; Hernandez, P ; Chapman, K R ; Cowie, R ; FitzGerald, J M ; Marciniuk, D D ; Maltais, F ; Buist, A S ; Road, J ; Hogg, J C ; Kirby, M ; Coxson, H ; Hague, C ; Leipsic, J ; O'Donnell, D E ; Aaron, S D ; CanCOLD Collaborative Research Group
descriptionBackgroundThere is limited data on the risk factors and phenotypical characteristics associated with spirometrically confirmed COPD in never-smokers in the general population.AimsTo compare the characteristics associated with COPD by gender and by severity of airway obstruction in never-smokers and in ever-smokers.MethodWe analysed the data from 5176 adults aged 40 years and older who participated in the initial cross-sectional phase of the population-based, prospective, multisite Canadian Cohort of Obstructive Lung Disease study. Never-smokers were defined as those with a lifetime exposure of <1/20 pack year. Logistic regressions were constructed to evaluate associations for ‘mild’ and ‘moderate-severe’ COPD defined by FEV1/FVC <5th centile (lower limits of normal). Analyses were performed using SAS V.9.1 (SAS Institute, Cary, North Carolina, USA).ResultsThe prevalence of COPD (FEV1/FVC
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subjectAdult ; Aged ; Airway Obstruction - physiopathology ; Canada ; Care and treatment ; Clinical trials ; Cross-Sectional Studies ; CT imaging ; Female ; Health aspects ; Hospitalization ; Humans ; Logistic Models ; Lung - physiopathology ; Lung diseases, Obstructive ; Male ; Middle Aged ; Observational studies ; Prevalence ; Prospective Studies ; Pulmonary Disease, Chronic Obstructive - physiopathology ; Risk Factors ; Smokers ; Smoking - adverse effects ; Tobacco Smoke Pollution - adverse effects ; Usage
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descriptionBackgroundThere is limited data on the risk factors and phenotypical characteristics associated with spirometrically confirmed COPD in never-smokers in the general population.AimsTo compare the characteristics associated with COPD by gender and by severity of airway obstruction in never-smokers and in ever-smokers.MethodWe analysed the data from 5176 adults aged 40 years and older who participated in the initial cross-sectional phase of the population-based, prospective, multisite Canadian Cohort of Obstructive Lung Disease study. Never-smokers were defined as those with a lifetime exposure of <1/20 pack year. Logistic regressions were constructed to evaluate associations for ‘mild’ and ‘moderate-severe’ COPD defined by FEV1/FVC <5th centile (lower limits of normal). Analyses were performed using SAS V.9.1 (SAS Institute, Cary, North Carolina, USA).ResultsThe prevalence of COPD (FEV1/FVC
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abstractBackgroundThere is limited data on the risk factors and phenotypical characteristics associated with spirometrically confirmed COPD in never-smokers in the general population.AimsTo compare the characteristics associated with COPD by gender and by severity of airway obstruction in never-smokers and in ever-smokers.MethodWe analysed the data from 5176 adults aged 40 years and older who participated in the initial cross-sectional phase of the population-based, prospective, multisite Canadian Cohort of Obstructive Lung Disease study. Never-smokers were defined as those with a lifetime exposure of <1/20 pack year. Logistic regressions were constructed to evaluate associations for ‘mild’ and ‘moderate-severe’ COPD defined by FEV1/FVC <5th centile (lower limits of normal). Analyses were performed using SAS V.9.1 (SAS Institute, Cary, North Carolina, USA).ResultsThe prevalence of COPD (FEV1/FVC
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pubBritish Medical Association
pmid26048404
doi10.1136/thoraxjnl-2015-206938
orcididhttps://orcid.org/0000-0002-0419-7862
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