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Determinants of 25-hydroxyvitamin D in older Irish adults

vitamin D deficiency is prevalent in older adults living in Northern Europe and is influenced by several factors which may vary significantly with age. we aimed to investigate the determinants of 25-hydroxyvitamin D [25(OH)D] in older Irish adults and in particular to examine the effect of supplemen... Full description

Journal Title: Age and ageing 2015, Vol.44 (5), p.847-853
Main Author: McCarroll, Kevin
Other Authors: Beirne, Avril , Casey, Miriam , McNulty, Helene , Ward, Mary , Hoey, Leane , Molloy, Anne , Laird, Eamon , Healy, Martin , Strain, J J , Cunningham, Conal
Format: Electronic Article Electronic Article
Language: English
Subjects:
Publisher: England: Oxford University Press
ID: ISSN: 0002-0729
Link: https://www.ncbi.nlm.nih.gov/pubmed/26265675
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title: Determinants of 25-hydroxyvitamin D in older Irish adults
format: Article
creator:
  • McCarroll, Kevin
  • Beirne, Avril
  • Casey, Miriam
  • McNulty, Helene
  • Ward, Mary
  • Hoey, Leane
  • Molloy, Anne
  • Laird, Eamon
  • Healy, Martin
  • Strain, J J
  • Cunningham, Conal
subjects:
  • Age Factors
  • Aged
  • Aged, 80 and over
  • Biomarkers - blood
  • Body mass index
  • Chromatography
  • Chromatography, Liquid
  • Correlation analysis
  • Dietary Supplements
  • Elderly
  • Female
  • Health aspects
  • Humans
  • Ireland - epidemiology
  • Male
  • Mass Spectrometry
  • Middle Aged
  • Northern Ireland - epidemiology
  • Older people
  • Prevalence
  • Protective Factors
  • Risk Factors
  • Seasons
  • Sunlight
  • Time Factors
  • Vitamin D
  • Vitamin D - analogs & derivatives
  • Vitamin D - blood
  • Vitamin D deficiency
  • Vitamin D Deficiency - blood
  • Vitamin D Deficiency - diagnosis
  • Vitamin D Deficiency - epidemiology
  • Vitamin D Deficiency - prevention & control
  • Vitamin deficiency
ispartof: Age and ageing, 2015, Vol.44 (5), p.847-853
description: vitamin D deficiency is prevalent in older adults living in Northern Europe and is influenced by several factors which may vary significantly with age. we aimed to investigate the determinants of 25-hydroxyvitamin D [25(OH)D] in older Irish adults and in particular to examine the effect of supplement use and surrogate markers of sun exposure. subjects were non-institutionalised community dwelling Irish adults aged over 60 years who were participants of a large cross-sectional study comprising three disease defined cohorts. Serum 25(OH)D was measured by liquid chromatography mass spectroscopy. Associations between 25(OH)D and potential confounders were explored in forward regression models in each cohort. the three cohorts comprised 1895, 1233 and 1316 participants (respective mean ages 70.1, 71.0 and 80.4 years). Statistical models explained between a fifth to a third of the variation in 25(OH)D. Supplement use and global solar radiation were positive predictors of 25(OH)D in all cohorts whereas the only universal negative predictor was body mass index. Supplement use was associated with a mean increase in 25(OH)D of between 21.4 and 35.4 nmol/l. The other main predictors varied by cohort but included sun holiday travel, enjoyment of sunshine when outside, use of vitamin D fortified milk, smoking, oily fish and egg consumption and physical frailty. supplement use was the most important determinant of vitamin D status. Vitamin D fortified milk and spending time in the sun, even in the oldest old may also be useful strategies to improve 25(OH)D.
language: eng
source:
identifier: ISSN: 0002-0729
fulltext: no_fulltext
issn:
  • 0002-0729
  • 1468-2834
url: Link


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titleDeterminants of 25-hydroxyvitamin D in older Irish adults
creatorMcCarroll, Kevin ; Beirne, Avril ; Casey, Miriam ; McNulty, Helene ; Ward, Mary ; Hoey, Leane ; Molloy, Anne ; Laird, Eamon ; Healy, Martin ; Strain, J J ; Cunningham, Conal
creatorcontribMcCarroll, Kevin ; Beirne, Avril ; Casey, Miriam ; McNulty, Helene ; Ward, Mary ; Hoey, Leane ; Molloy, Anne ; Laird, Eamon ; Healy, Martin ; Strain, J J ; Cunningham, Conal
descriptionvitamin D deficiency is prevalent in older adults living in Northern Europe and is influenced by several factors which may vary significantly with age. we aimed to investigate the determinants of 25-hydroxyvitamin D [25(OH)D] in older Irish adults and in particular to examine the effect of supplement use and surrogate markers of sun exposure. subjects were non-institutionalised community dwelling Irish adults aged over 60 years who were participants of a large cross-sectional study comprising three disease defined cohorts. Serum 25(OH)D was measured by liquid chromatography mass spectroscopy. Associations between 25(OH)D and potential confounders were explored in forward regression models in each cohort. the three cohorts comprised 1895, 1233 and 1316 participants (respective mean ages 70.1, 71.0 and 80.4 years). Statistical models explained between a fifth to a third of the variation in 25(OH)D. Supplement use and global solar radiation were positive predictors of 25(OH)D in all cohorts whereas the only universal negative predictor was body mass index. Supplement use was associated with a mean increase in 25(OH)D of between 21.4 and 35.4 nmol/l. The other main predictors varied by cohort but included sun holiday travel, enjoyment of sunshine when outside, use of vitamin D fortified milk, smoking, oily fish and egg consumption and physical frailty. supplement use was the most important determinant of vitamin D status. Vitamin D fortified milk and spending time in the sun, even in the oldest old may also be useful strategies to improve 25(OH)D.
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subjectAge Factors ; Aged ; Aged, 80 and over ; Biomarkers - blood ; Body mass index ; Chromatography ; Chromatography, Liquid ; Correlation analysis ; Dietary Supplements ; Elderly ; Female ; Health aspects ; Humans ; Ireland - epidemiology ; Male ; Mass Spectrometry ; Middle Aged ; Northern Ireland - epidemiology ; Older people ; Prevalence ; Protective Factors ; Risk Factors ; Seasons ; Sunlight ; Time Factors ; Vitamin D ; Vitamin D - analogs & derivatives ; Vitamin D - blood ; Vitamin D deficiency ; Vitamin D Deficiency - blood ; Vitamin D Deficiency - diagnosis ; Vitamin D Deficiency - epidemiology ; Vitamin D Deficiency - prevention & control ; Vitamin deficiency
ispartofAge and ageing, 2015, Vol.44 (5), p.847-853
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0The Author 2015. Published by Oxford University Press on behalf of the British Geriatrics Society. All rights reserved. For Permissions, please email: journals.permissions@oup.com.
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descriptionvitamin D deficiency is prevalent in older adults living in Northern Europe and is influenced by several factors which may vary significantly with age. we aimed to investigate the determinants of 25-hydroxyvitamin D [25(OH)D] in older Irish adults and in particular to examine the effect of supplement use and surrogate markers of sun exposure. subjects were non-institutionalised community dwelling Irish adults aged over 60 years who were participants of a large cross-sectional study comprising three disease defined cohorts. Serum 25(OH)D was measured by liquid chromatography mass spectroscopy. Associations between 25(OH)D and potential confounders were explored in forward regression models in each cohort. the three cohorts comprised 1895, 1233 and 1316 participants (respective mean ages 70.1, 71.0 and 80.4 years). Statistical models explained between a fifth to a third of the variation in 25(OH)D. Supplement use and global solar radiation were positive predictors of 25(OH)D in all cohorts whereas the only universal negative predictor was body mass index. Supplement use was associated with a mean increase in 25(OH)D of between 21.4 and 35.4 nmol/l. The other main predictors varied by cohort but included sun holiday travel, enjoyment of sunshine when outside, use of vitamin D fortified milk, smoking, oily fish and egg consumption and physical frailty. supplement use was the most important determinant of vitamin D status. Vitamin D fortified milk and spending time in the sun, even in the oldest old may also be useful strategies to improve 25(OH)D.
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32Vitamin D Deficiency - prevention & control
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titleDeterminants of 25-hydroxyvitamin D in older Irish adults
authorMcCarroll, Kevin ; Beirne, Avril ; Casey, Miriam ; McNulty, Helene ; Ward, Mary ; Hoey, Leane ; Molloy, Anne ; Laird, Eamon ; Healy, Martin ; Strain, J J ; Cunningham, Conal
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abstractvitamin D deficiency is prevalent in older adults living in Northern Europe and is influenced by several factors which may vary significantly with age. we aimed to investigate the determinants of 25-hydroxyvitamin D [25(OH)D] in older Irish adults and in particular to examine the effect of supplement use and surrogate markers of sun exposure. subjects were non-institutionalised community dwelling Irish adults aged over 60 years who were participants of a large cross-sectional study comprising three disease defined cohorts. Serum 25(OH)D was measured by liquid chromatography mass spectroscopy. Associations between 25(OH)D and potential confounders were explored in forward regression models in each cohort. the three cohorts comprised 1895, 1233 and 1316 participants (respective mean ages 70.1, 71.0 and 80.4 years). Statistical models explained between a fifth to a third of the variation in 25(OH)D. Supplement use and global solar radiation were positive predictors of 25(OH)D in all cohorts whereas the only universal negative predictor was body mass index. Supplement use was associated with a mean increase in 25(OH)D of between 21.4 and 35.4 nmol/l. The other main predictors varied by cohort but included sun holiday travel, enjoyment of sunshine when outside, use of vitamin D fortified milk, smoking, oily fish and egg consumption and physical frailty. supplement use was the most important determinant of vitamin D status. Vitamin D fortified milk and spending time in the sun, even in the oldest old may also be useful strategies to improve 25(OH)D.
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