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Optimal approaches to diabetic patients with multivessel disease

Abstract The pathophysiology of diabetes and systemic insulin resistance contributes to the nature of diffuse atherosclerosis and a high prevalence of multivessel coronary artery disease (CAD) in diabetic patients. The optimal approach to this patient population remains a subject of an ongoing discu... Full description

Journal Title: Trends in cardiovascular medicine 2015, Vol.25 (7), p.625-631
Main Author: Razzouk, Louai, MD, MPH
Other Authors: Farkouh, Michael E., MD, MSc
Format: Electronic Article Electronic Article
Language: English
Subjects:
Quelle: Alma/SFX Local Collection
Publisher: United States: Elsevier Inc
ID: ISSN: 1050-1738
Link: https://www.ncbi.nlm.nih.gov/pubmed/26398271
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title: Optimal approaches to diabetic patients with multivessel disease
format: Article
creator:
  • Razzouk, Louai, MD, MPH
  • Farkouh, Michael E., MD, MSc
subjects:
  • Arteriosclerosis
  • Atherosclerosis
  • Biomarkers - blood
  • Blood Glucose - metabolism
  • Cardiovascular
  • Cardiovascular Agents - therapeutic use
  • Care and treatment
  • Clinical trials
  • Coronary artery
  • Coronary Artery Bypass - adverse effects
  • Coronary Artery Bypass - economics
  • Coronary Artery Bypass - mortality
  • Coronary Artery Disease - blood
  • Coronary Artery Disease - diagnosis
  • Coronary Artery Disease - economics
  • Coronary Artery Disease - mortality
  • Coronary Artery Disease - therapy
  • Coronary heart disease
  • Cost-Benefit Analysis
  • Diabetes
  • Diabetes mellitus
  • Diabetic Angiopathies - blood
  • Diabetic Angiopathies - diagnosis
  • Diabetic Angiopathies - economics
  • Diabetic Angiopathies - mortality
  • Diabetic Angiopathies - therapy
  • Diabetics
  • Health Care Costs
  • Heart attacks
  • Heart diseases
  • Humans
  • Insulin
  • Insulin Resistance
  • Mortality
  • Patient Selection
  • Patients
  • Percutaneous Coronary Intervention - adverse effects
  • Percutaneous Coronary Intervention - economics
  • Percutaneous Coronary Intervention - instrumentation
  • Percutaneous Coronary Intervention - mortality
  • Quality of Life
  • Risk Factors
  • Risk Reduction Behavior
  • Stents
  • Time Factors
  • Treatment Outcome
ispartof: Trends in cardiovascular medicine, 2015, Vol.25 (7), p.625-631
description: Abstract The pathophysiology of diabetes and systemic insulin resistance contributes to the nature of diffuse atherosclerosis and a high prevalence of multivessel coronary artery disease (CAD) in diabetic patients. The optimal approach to this patient population remains a subject of an ongoing discussion. In this review, we give an overview of the unique pathophysiology of CAD in patients with diabetes, summarize the current state of therapies available, and compare modalities of revascularization that have been investigated in recent clinical trials. We conclude by highlighting the importance of a comprehensive heart team approach to every patient while accommodating both patient preference and quality-of-life decisions.
language: eng
source: Alma/SFX Local Collection
identifier: ISSN: 1050-1738
fulltext: fulltext
issn:
  • 1050-1738
  • 1873-2615
url: Link


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descriptionAbstract The pathophysiology of diabetes and systemic insulin resistance contributes to the nature of diffuse atherosclerosis and a high prevalence of multivessel coronary artery disease (CAD) in diabetic patients. The optimal approach to this patient population remains a subject of an ongoing discussion. In this review, we give an overview of the unique pathophysiology of CAD in patients with diabetes, summarize the current state of therapies available, and compare modalities of revascularization that have been investigated in recent clinical trials. We conclude by highlighting the importance of a comprehensive heart team approach to every patient while accommodating both patient preference and quality-of-life decisions.
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subjectArteriosclerosis ; Atherosclerosis ; Biomarkers - blood ; Blood Glucose - metabolism ; Cardiovascular ; Cardiovascular Agents - therapeutic use ; Care and treatment ; Clinical trials ; Coronary artery ; Coronary Artery Bypass - adverse effects ; Coronary Artery Bypass - economics ; Coronary Artery Bypass - mortality ; Coronary Artery Disease - blood ; Coronary Artery Disease - diagnosis ; Coronary Artery Disease - economics ; Coronary Artery Disease - mortality ; Coronary Artery Disease - therapy ; Coronary heart disease ; Cost-Benefit Analysis ; Diabetes ; Diabetes mellitus ; Diabetic Angiopathies - blood ; Diabetic Angiopathies - diagnosis ; Diabetic Angiopathies - economics ; Diabetic Angiopathies - mortality ; Diabetic Angiopathies - therapy ; Diabetics ; Health Care Costs ; Heart attacks ; Heart diseases ; Humans ; Insulin ; Insulin Resistance ; Mortality ; Patient Selection ; Patients ; Percutaneous Coronary Intervention - adverse effects ; Percutaneous Coronary Intervention - economics ; Percutaneous Coronary Intervention - instrumentation ; Percutaneous Coronary Intervention - mortality ; Quality of Life ; Risk Factors ; Risk Reduction Behavior ; Stents ; Time Factors ; Treatment Outcome
ispartofTrends in cardiovascular medicine, 2015, Vol.25 (7), p.625-631
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descriptionAbstract The pathophysiology of diabetes and systemic insulin resistance contributes to the nature of diffuse atherosclerosis and a high prevalence of multivessel coronary artery disease (CAD) in diabetic patients. The optimal approach to this patient population remains a subject of an ongoing discussion. In this review, we give an overview of the unique pathophysiology of CAD in patients with diabetes, summarize the current state of therapies available, and compare modalities of revascularization that have been investigated in recent clinical trials. We conclude by highlighting the importance of a comprehensive heart team approach to every patient while accommodating both patient preference and quality-of-life decisions.
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6Care and treatment
7Clinical trials
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10Coronary Artery Bypass - economics
11Coronary Artery Bypass - mortality
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27Health Care Costs
28Heart attacks
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34Patient Selection
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36Percutaneous Coronary Intervention - adverse effects
37Percutaneous Coronary Intervention - economics
38Percutaneous Coronary Intervention - instrumentation
39Percutaneous Coronary Intervention - mortality
40Quality of Life
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43Stents
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abstractAbstract The pathophysiology of diabetes and systemic insulin resistance contributes to the nature of diffuse atherosclerosis and a high prevalence of multivessel coronary artery disease (CAD) in diabetic patients. The optimal approach to this patient population remains a subject of an ongoing discussion. In this review, we give an overview of the unique pathophysiology of CAD in patients with diabetes, summarize the current state of therapies available, and compare modalities of revascularization that have been investigated in recent clinical trials. We conclude by highlighting the importance of a comprehensive heart team approach to every patient while accommodating both patient preference and quality-of-life decisions.
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