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Association between clinical variables and mortality after parathyroidectomy in maintenance hemodialysis patients

Abstract Background We investigated factors associated with all-cause mortality and cardiovascular disease (CVD)-associated mortality after parathyroidectomy (PTX) in patients on maintenance hemodialysis (HD). Methods Our study population consisted of 161 consecutive HD patients who underwent PTX be... Full description

Journal Title: The American journal of surgery 2016, Vol.213 (1), p.140-145
Main Author: Chen, Jin-Bor, M.D
Other Authors: Chou, Fong-Fu, M.D , Yang, Cheng-Hong, Ph.D , Hua, Moi-Sin, Ph.D
Format: Electronic Article Electronic Article
Language: English
Subjects:
Age
Quelle: Alma/SFX Local Collection
Publisher: United States: Elsevier Inc
ID: ISSN: 0002-9610
Link: https://www.ncbi.nlm.nih.gov/pubmed/27469221
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title: Association between clinical variables and mortality after parathyroidectomy in maintenance hemodialysis patients
format: Article
creator:
  • Chen, Jin-Bor, M.D
  • Chou, Fong-Fu, M.D
  • Yang, Cheng-Hong, Ph.D
  • Hua, Moi-Sin, Ph.D
subjects:
  • Abridged Index Medicus
  • Adolescent
  • Adult
  • Age
  • Aged
  • All-cause mortality
  • Cardiovascular disease
  • Cardiovascular Diseases - mortality
  • Cardiovascular mortality
  • Diabetes
  • Female
  • Gender
  • Health risk assessment
  • Hemodialysis
  • Humans
  • Hyperparathyroidism, Secondary - mortality
  • Hyperparathyroidism, Secondary - surgery
  • Kaplan-Meier Estimate
  • Kidney Failure, Chronic - complications
  • Kidney Failure, Chronic - mortality
  • Kidney Failure, Chronic - therapy
  • Male
  • Medical colleges
  • Middle Aged
  • Mortality
  • Nitrogen
  • Parathyroidectomy
  • Patients
  • Potassium
  • Renal Dialysis
  • Retrospective Studies
  • Studies
  • Surgery
  • Survival analysis
  • Taiwan
  • Variables
  • Young Adult
ispartof: The American journal of surgery, 2016, Vol.213 (1), p.140-145
description: Abstract Background We investigated factors associated with all-cause mortality and cardiovascular disease (CVD)-associated mortality after parathyroidectomy (PTX) in patients on maintenance hemodialysis (HD). Methods Our study population consisted of 161 consecutive HD patients who underwent PTX before 2009 and 354 consecutive HD patients without PTX as controls from those visiting the Kaohsiung Chang Gung Memorial Hospital, Taiwan between 2009 and 2013. All-cause and CVD mortality with clinical variables were compared in PTX and non-PTX HD patients. Results PTX patients had significantly lower all-cause and CVD mortality than controls. Multivariate logistic regression analyses showed PTX patients had a lower odds ratio for all-cause mortality than those without (odds ratio = .35, 95% confidence interval = .16 to .74). Association analysis based on clinical variables revealed patients with higher hemoglobin, albumin, creatinine, and HD adequacy index-Kt/V levels had significantly decreased risk of all-cause mortality. Conclusions PTX in HD patients reduces the risk of death.
language: eng
source: Alma/SFX Local Collection
identifier: ISSN: 0002-9610
fulltext: fulltext
issn:
  • 0002-9610
  • 1879-1883
url: Link


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descriptionAbstract Background We investigated factors associated with all-cause mortality and cardiovascular disease (CVD)-associated mortality after parathyroidectomy (PTX) in patients on maintenance hemodialysis (HD). Methods Our study population consisted of 161 consecutive HD patients who underwent PTX before 2009 and 354 consecutive HD patients without PTX as controls from those visiting the Kaohsiung Chang Gung Memorial Hospital, Taiwan between 2009 and 2013. All-cause and CVD mortality with clinical variables were compared in PTX and non-PTX HD patients. Results PTX patients had significantly lower all-cause and CVD mortality than controls. Multivariate logistic regression analyses showed PTX patients had a lower odds ratio for all-cause mortality than those without (odds ratio = .35, 95% confidence interval = .16 to .74). Association analysis based on clinical variables revealed patients with higher hemoglobin, albumin, creatinine, and HD adequacy index-Kt/V levels had significantly decreased risk of all-cause mortality. Conclusions PTX in HD patients reduces the risk of death.
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subjectAbridged Index Medicus ; Adolescent ; Adult ; Age ; Aged ; All-cause mortality ; Cardiovascular disease ; Cardiovascular Diseases - mortality ; Cardiovascular mortality ; Diabetes ; Female ; Gender ; Health risk assessment ; Hemodialysis ; Humans ; Hyperparathyroidism, Secondary - mortality ; Hyperparathyroidism, Secondary - surgery ; Kaplan-Meier Estimate ; Kidney Failure, Chronic - complications ; Kidney Failure, Chronic - mortality ; Kidney Failure, Chronic - therapy ; Male ; Medical colleges ; Middle Aged ; Mortality ; Nitrogen ; Parathyroidectomy ; Patients ; Potassium ; Renal Dialysis ; Retrospective Studies ; Studies ; Surgery ; Survival analysis ; Taiwan ; Variables ; Young Adult
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descriptionAbstract Background We investigated factors associated with all-cause mortality and cardiovascular disease (CVD)-associated mortality after parathyroidectomy (PTX) in patients on maintenance hemodialysis (HD). Methods Our study population consisted of 161 consecutive HD patients who underwent PTX before 2009 and 354 consecutive HD patients without PTX as controls from those visiting the Kaohsiung Chang Gung Memorial Hospital, Taiwan between 2009 and 2013. All-cause and CVD mortality with clinical variables were compared in PTX and non-PTX HD patients. Results PTX patients had significantly lower all-cause and CVD mortality than controls. Multivariate logistic regression analyses showed PTX patients had a lower odds ratio for all-cause mortality than those without (odds ratio = .35, 95% confidence interval = .16 to .74). Association analysis based on clinical variables revealed patients with higher hemoglobin, albumin, creatinine, and HD adequacy index-Kt/V levels had significantly decreased risk of all-cause mortality. Conclusions PTX in HD patients reduces the risk of death.
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25Nitrogen
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27Patients
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titleAssociation between clinical variables and mortality after parathyroidectomy in maintenance hemodialysis patients
authorChen, Jin-Bor, M.D ; Chou, Fong-Fu, M.D ; Yang, Cheng-Hong, Ph.D ; Hua, Moi-Sin, Ph.D
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abstractAbstract Background We investigated factors associated with all-cause mortality and cardiovascular disease (CVD)-associated mortality after parathyroidectomy (PTX) in patients on maintenance hemodialysis (HD). Methods Our study population consisted of 161 consecutive HD patients who underwent PTX before 2009 and 354 consecutive HD patients without PTX as controls from those visiting the Kaohsiung Chang Gung Memorial Hospital, Taiwan between 2009 and 2013. All-cause and CVD mortality with clinical variables were compared in PTX and non-PTX HD patients. Results PTX patients had significantly lower all-cause and CVD mortality than controls. Multivariate logistic regression analyses showed PTX patients had a lower odds ratio for all-cause mortality than those without (odds ratio = .35, 95% confidence interval = .16 to .74). Association analysis based on clinical variables revealed patients with higher hemoglobin, albumin, creatinine, and HD adequacy index-Kt/V levels had significantly decreased risk of all-cause mortality. Conclusions PTX in HD patients reduces the risk of death.
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