schliessen

Filtern

 

Bibliotheken

High-Speed and Scalable Whole-Brain Imaging in Rodents and Primates

Subcellular resolution imaging of the whole brain and subsequent image analysis are prerequisites for understanding anatomical and functional brain networks. Here, we have developed a very high-speed serial-sectioning imaging system named FAST (block-face serial microscopy tomography), which acquire... Full description

Journal Title: Neuron (Cambridge Mass.), 2017, Vol.94 (6), p.1085-1100.e6
Main Author: Seiriki, Kaoru
Other Authors: Kasai, Atsushi , Hashimoto, Takeshi , Schulze, Wiebke , Niu, Misaki , Yamaguchi, Shun , Nakazawa, Takanobu , Inoue, Ken-ichi , Uezono, Shiori , Takada, Masahiko , Naka, Yuichiro , Igarashi, Hisato , Tanuma, Masato , Waschek, James A , Ago, Yukio , Tanaka, Kenji F , Hayata-Takano, Atsuko , Nagayasu, Kazuki , Shintani, Norihito , Hashimoto, Ryota , Kunii, Yasuto , Hino, Mizuki , Matsumoto, Junya , Yabe, Hirooki , Nagai, Takeharu , Fujita, Katsumasa , Matsuda, Toshio , Takuma, Kazuhiro , Baba, Akemichi , Hashimoto, Hitoshi
Format: Electronic Article Electronic Article
Language: English
Subjects:
Quelle: Alma/SFX Local Collection
Publisher: United States: Elsevier Inc
ID: ISSN: 0896-6273
Link: https://www.ncbi.nlm.nih.gov/pubmed/28641108
Zum Text:
SendSend as email Add to Book BagAdd to Book Bag
Staff View
recordid: cdi_proquest_miscellaneous_1913395799
title: High-Speed and Scalable Whole-Brain Imaging in Rodents and Primates
format: Article
creator:
  • Seiriki, Kaoru
  • Kasai, Atsushi
  • Hashimoto, Takeshi
  • Schulze, Wiebke
  • Niu, Misaki
  • Yamaguchi, Shun
  • Nakazawa, Takanobu
  • Inoue, Ken-ichi
  • Uezono, Shiori
  • Takada, Masahiko
  • Naka, Yuichiro
  • Igarashi, Hisato
  • Tanuma, Masato
  • Waschek, James A
  • Ago, Yukio
  • Tanaka, Kenji F
  • Hayata-Takano, Atsuko
  • Nagayasu, Kazuki
  • Shintani, Norihito
  • Hashimoto, Ryota
  • Kunii, Yasuto
  • Hino, Mizuki
  • Matsumoto, Junya
  • Yabe, Hirooki
  • Nagai, Takeharu
  • Fujita, Katsumasa
  • Matsuda, Toshio
  • Takuma, Kazuhiro
  • Baba, Akemichi
  • Hashimoto, Hitoshi
subjects:
  • Aged, 80 and over
  • Animal models
  • Animals
  • Automation
  • Brain
  • Brain - anatomy & histology
  • Brain - diagnostic imaging
  • Callithrix
  • cell distribution
  • Female
  • Fluorescence microscopy
  • Gene expression
  • High resolution
  • human post-mortem brain
  • Humans
  • Image acquisition
  • Image analysis
  • Image processing
  • Image Processing, Computer-Assisted - methods
  • Image resolution
  • Imaging
  • Imaging systems
  • Imaging, Three-Dimensional - methods
  • Male
  • Medical imaging
  • Methods
  • Mice
  • Microscopy
  • Microscopy - methods
  • Microscopy, Fluorescence - methods
  • Monkeys & apes
  • Morphology
  • Neurites
  • Neuroimaging
  • Neuroimaging - methods
  • Neurons
  • Neurosciences
  • non-human primate brain
  • Open source software
  • Primates
  • Rodents
  • Sectioning
  • Spatial discrimination
  • Spatial resolution
  • subcellular resolution
  • Tomography - methods
  • whole-brain imaging
ispartof: Neuron (Cambridge, Mass.), 2017, Vol.94 (6), p.1085-1100.e6
description: Subcellular resolution imaging of the whole brain and subsequent image analysis are prerequisites for understanding anatomical and functional brain networks. Here, we have developed a very high-speed serial-sectioning imaging system named FAST (block-face serial microscopy tomography), which acquires high-resolution images of a whole mouse brain in a speed range comparable to that of light-sheet fluorescence microscopy. FAST enables complete visualization of the brain at a resolution sufficient to resolve all cells and their subcellular structures. FAST renders unbiased quantitative group comparisons of normal and disease model brain cells for the whole brain at a high spatial resolution. Furthermore, FAST is highly scalable to non-human primate brains and human postmortem brain tissues, and can visualize neuronal projections in a whole adult marmoset brain. Thus, FAST provides new opportunities for global approaches that will allow for a better understanding of brain systems in multiple animal models and in human diseases. •FAST acquires whole-brain subcellular resolution images with unprecedented speed•FAST is scalable to non-human primate brains and human postmortem brain tissues•FAST renders unbiased group comparisons of the whole-brain high-resolution images Seiriki et al. developed a very high-speed serial-sectioning imaging system named FAST that allows whole-brain imaging at a spatial resolution to image all brain cells and long-range neuronal projections in experimental animal models and facilitates animal-to-human translational research.
language: eng
source: Alma/SFX Local Collection
identifier: ISSN: 0896-6273
fulltext: fulltext
issn:
  • 0896-6273
  • 1097-4199
url: Link


@attributes
NO1
SEARCH_ENGINEprimo_central_multiple_fe
SEARCH_ENGINE_TYPEPrimo Central Search Engine
RANK2.699587
LOCALfalse
PrimoNMBib
record
control
sourceidgale_proqu
recordidTN_cdi_proquest_miscellaneous_1913395799
sourceformatXML
sourcesystemPC
galeidA498024389
sourcerecordidA498024389
originalsourceidFETCH-LOGICAL-1516t-36124df43678c6cbe6b6e2723e5f297b6526b398b0f20a57a02ce26252d8d6203
addsrcrecordideNqNkc-L1DAcxYMo7rj6H4gUvHhpzY8maTwI66DuwoLiKh5Dmnw7m6GTjEkr7H-_qV097EElhxfC5z0eeQg9J7ghmIjX-ybAnGJoKCaywbwp8gBtCFaybolSD9EGd0rUgkp2gp7kvMeYtFyRx-iEdqIlBHcbtD33u-v66gjgKhNcdWXNaPoRqu_XcYT6XTI-VBcHs_NhV5Xrl-ggTPkX-zn5g5kgP0WPBjNmeHanp-jbh_dft-f15aePF9uzy5pwIqaaCUJbN7RMyM4K24PoBVBJGfCBKtkLTkXPVNfjgWLDpcHUAhWUU9c5QTE7Ra_W3GOKP2bIkz74bGEcTYA4Z00UYUxxqVRBX95D93FOobRbKCoklkwUqlmpnRlB-zDEKRlbjoODtzHA4Mv7GadEYoJb_r-GVnWYtqxberSrwaaYc4JBH5dPSzeaYL3MqPd6nVEvM2rMdZFie3FXf-4P4P6Yfu9WgDf3cq2fzORjKIX8-K_0t6sZylg_PSSdrYdgwfkEdtIu-r8H3AJyEL-v
sourcetypeAggregation Database
isCDItrue
recordtypearticle
pqid1912670736
display
typearticle
titleHigh-Speed and Scalable Whole-Brain Imaging in Rodents and Primates
sourceAlma/SFX Local Collection
creatorSeiriki, Kaoru ; Kasai, Atsushi ; Hashimoto, Takeshi ; Schulze, Wiebke ; Niu, Misaki ; Yamaguchi, Shun ; Nakazawa, Takanobu ; Inoue, Ken-ichi ; Uezono, Shiori ; Takada, Masahiko ; Naka, Yuichiro ; Igarashi, Hisato ; Tanuma, Masato ; Waschek, James A ; Ago, Yukio ; Tanaka, Kenji F ; Hayata-Takano, Atsuko ; Nagayasu, Kazuki ; Shintani, Norihito ; Hashimoto, Ryota ; Kunii, Yasuto ; Hino, Mizuki ; Matsumoto, Junya ; Yabe, Hirooki ; Nagai, Takeharu ; Fujita, Katsumasa ; Matsuda, Toshio ; Takuma, Kazuhiro ; Baba, Akemichi ; Hashimoto, Hitoshi
creatorcontribSeiriki, Kaoru ; Kasai, Atsushi ; Hashimoto, Takeshi ; Schulze, Wiebke ; Niu, Misaki ; Yamaguchi, Shun ; Nakazawa, Takanobu ; Inoue, Ken-ichi ; Uezono, Shiori ; Takada, Masahiko ; Naka, Yuichiro ; Igarashi, Hisato ; Tanuma, Masato ; Waschek, James A ; Ago, Yukio ; Tanaka, Kenji F ; Hayata-Takano, Atsuko ; Nagayasu, Kazuki ; Shintani, Norihito ; Hashimoto, Ryota ; Kunii, Yasuto ; Hino, Mizuki ; Matsumoto, Junya ; Yabe, Hirooki ; Nagai, Takeharu ; Fujita, Katsumasa ; Matsuda, Toshio ; Takuma, Kazuhiro ; Baba, Akemichi ; Hashimoto, Hitoshi
descriptionSubcellular resolution imaging of the whole brain and subsequent image analysis are prerequisites for understanding anatomical and functional brain networks. Here, we have developed a very high-speed serial-sectioning imaging system named FAST (block-face serial microscopy tomography), which acquires high-resolution images of a whole mouse brain in a speed range comparable to that of light-sheet fluorescence microscopy. FAST enables complete visualization of the brain at a resolution sufficient to resolve all cells and their subcellular structures. FAST renders unbiased quantitative group comparisons of normal and disease model brain cells for the whole brain at a high spatial resolution. Furthermore, FAST is highly scalable to non-human primate brains and human postmortem brain tissues, and can visualize neuronal projections in a whole adult marmoset brain. Thus, FAST provides new opportunities for global approaches that will allow for a better understanding of brain systems in multiple animal models and in human diseases. •FAST acquires whole-brain subcellular resolution images with unprecedented speed•FAST is scalable to non-human primate brains and human postmortem brain tissues•FAST renders unbiased group comparisons of the whole-brain high-resolution images Seiriki et al. developed a very high-speed serial-sectioning imaging system named FAST that allows whole-brain imaging at a spatial resolution to image all brain cells and long-range neuronal projections in experimental animal models and facilitates animal-to-human translational research.
identifier
0ISSN: 0896-6273
1EISSN: 1097-4199
2DOI: 10.1016/j.neuron.2017.05.017
3PMID: 28641108
languageeng
publisherUnited States: Elsevier Inc
subjectAged, 80 and over ; Animal models ; Animals ; Automation ; Brain ; Brain - anatomy & histology ; Brain - diagnostic imaging ; Callithrix ; cell distribution ; Female ; Fluorescence microscopy ; Gene expression ; High resolution ; human post-mortem brain ; Humans ; Image acquisition ; Image analysis ; Image processing ; Image Processing, Computer-Assisted - methods ; Image resolution ; Imaging ; Imaging systems ; Imaging, Three-Dimensional - methods ; Male ; Medical imaging ; Methods ; Mice ; Microscopy ; Microscopy - methods ; Microscopy, Fluorescence - methods ; Monkeys & apes ; Morphology ; Neurites ; Neuroimaging ; Neuroimaging - methods ; Neurons ; Neurosciences ; non-human primate brain ; Open source software ; Primates ; Rodents ; Sectioning ; Spatial discrimination ; Spatial resolution ; subcellular resolution ; Tomography - methods ; whole-brain imaging
ispartofNeuron (Cambridge, Mass.), 2017, Vol.94 (6), p.1085-1100.e6
rights
02017 Elsevier Inc.
1Copyright © 2017 Elsevier Inc. All rights reserved.
2COPYRIGHT 2017 Elsevier B.V.
3Copyright Elsevier Limited Jun 21, 2017
lds50peer_reviewed
oafree_for_read
citedbyFETCH-LOGICAL-1516t-36124df43678c6cbe6b6e2723e5f297b6526b398b0f20a57a02ce26252d8d6203
links
openurl$$Topenurl_article
openurlfulltext$$Topenurlfull_article
thumbnail$$Usyndetics_thumb_exl
backlink$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28641108$$D View this record in MEDLINE/PubMed
search
creatorcontrib
0Seiriki, Kaoru
1Kasai, Atsushi
2Hashimoto, Takeshi
3Schulze, Wiebke
4Niu, Misaki
5Yamaguchi, Shun
6Nakazawa, Takanobu
7Inoue, Ken-ichi
8Uezono, Shiori
9Takada, Masahiko
10Naka, Yuichiro
11Igarashi, Hisato
12Tanuma, Masato
13Waschek, James A
14Ago, Yukio
15Tanaka, Kenji F
16Hayata-Takano, Atsuko
17Nagayasu, Kazuki
18Shintani, Norihito
19Hashimoto, Ryota
20Kunii, Yasuto
21Hino, Mizuki
22Matsumoto, Junya
23Yabe, Hirooki
24Nagai, Takeharu
25Fujita, Katsumasa
26Matsuda, Toshio
27Takuma, Kazuhiro
28Baba, Akemichi
29Hashimoto, Hitoshi
title
0High-Speed and Scalable Whole-Brain Imaging in Rodents and Primates
1Neuron (Cambridge, Mass.)
addtitleNeuron
descriptionSubcellular resolution imaging of the whole brain and subsequent image analysis are prerequisites for understanding anatomical and functional brain networks. Here, we have developed a very high-speed serial-sectioning imaging system named FAST (block-face serial microscopy tomography), which acquires high-resolution images of a whole mouse brain in a speed range comparable to that of light-sheet fluorescence microscopy. FAST enables complete visualization of the brain at a resolution sufficient to resolve all cells and their subcellular structures. FAST renders unbiased quantitative group comparisons of normal and disease model brain cells for the whole brain at a high spatial resolution. Furthermore, FAST is highly scalable to non-human primate brains and human postmortem brain tissues, and can visualize neuronal projections in a whole adult marmoset brain. Thus, FAST provides new opportunities for global approaches that will allow for a better understanding of brain systems in multiple animal models and in human diseases. •FAST acquires whole-brain subcellular resolution images with unprecedented speed•FAST is scalable to non-human primate brains and human postmortem brain tissues•FAST renders unbiased group comparisons of the whole-brain high-resolution images Seiriki et al. developed a very high-speed serial-sectioning imaging system named FAST that allows whole-brain imaging at a spatial resolution to image all brain cells and long-range neuronal projections in experimental animal models and facilitates animal-to-human translational research.
subject
0Aged, 80 and over
1Animal models
2Animals
3Automation
4Brain
5Brain - anatomy & histology
6Brain - diagnostic imaging
7Callithrix
8cell distribution
9Female
10Fluorescence microscopy
11Gene expression
12High resolution
13human post-mortem brain
14Humans
15Image acquisition
16Image analysis
17Image processing
18Image Processing, Computer-Assisted - methods
19Image resolution
20Imaging
21Imaging systems
22Imaging, Three-Dimensional - methods
23Male
24Medical imaging
25Methods
26Mice
27Microscopy
28Microscopy - methods
29Microscopy, Fluorescence - methods
30Monkeys & apes
31Morphology
32Neurites
33Neuroimaging
34Neuroimaging - methods
35Neurons
36Neurosciences
37non-human primate brain
38Open source software
39Primates
40Rodents
41Sectioning
42Spatial discrimination
43Spatial resolution
44subcellular resolution
45Tomography - methods
46whole-brain imaging
issn
00896-6273
11097-4199
fulltexttrue
rsrctypearticle
creationdate2017
recordtypearticle
recordideNqNkc-L1DAcxYMo7rj6H4gUvHhpzY8maTwI66DuwoLiKh5Dmnw7m6GTjEkr7H-_qV097EElhxfC5z0eeQg9J7ghmIjX-ybAnGJoKCaywbwp8gBtCFaybolSD9EGd0rUgkp2gp7kvMeYtFyRx-iEdqIlBHcbtD33u-v66gjgKhNcdWXNaPoRqu_XcYT6XTI-VBcHs_NhV5Xrl-ggTPkX-zn5g5kgP0WPBjNmeHanp-jbh_dft-f15aePF9uzy5pwIqaaCUJbN7RMyM4K24PoBVBJGfCBKtkLTkXPVNfjgWLDpcHUAhWUU9c5QTE7Ra_W3GOKP2bIkz74bGEcTYA4Z00UYUxxqVRBX95D93FOobRbKCoklkwUqlmpnRlB-zDEKRlbjoODtzHA4Mv7GadEYoJb_r-GVnWYtqxberSrwaaYc4JBH5dPSzeaYL3MqPd6nVEvM2rMdZFie3FXf-4P4P6Yfu9WgDf3cq2fzORjKIX8-K_0t6sZylg_PSSdrYdgwfkEdtIu-r8H3AJyEL-v
startdate20170621
enddate20170621
creator
0Seiriki, Kaoru
1Kasai, Atsushi
2Hashimoto, Takeshi
3Schulze, Wiebke
4Niu, Misaki
5Yamaguchi, Shun
6Nakazawa, Takanobu
7Inoue, Ken-ichi
8Uezono, Shiori
9Takada, Masahiko
10Naka, Yuichiro
11Igarashi, Hisato
12Tanuma, Masato
13Waschek, James A
14Ago, Yukio
15Tanaka, Kenji F
16Hayata-Takano, Atsuko
17Nagayasu, Kazuki
18Shintani, Norihito
19Hashimoto, Ryota
20Kunii, Yasuto
21Hino, Mizuki
22Matsumoto, Junya
23Yabe, Hirooki
24Nagai, Takeharu
25Fujita, Katsumasa
26Matsuda, Toshio
27Takuma, Kazuhiro
28Baba, Akemichi
29Hashimoto, Hitoshi
general
0Elsevier Inc
1Elsevier B.V
2Elsevier Limited
scope
06I.
1AAFTH
2CGR
3CUY
4CVF
5ECM
6EIF
7NPM
8AAYXX
9CITATION
10BSHEE
117QP
127QR
137TK
148FD
15FR3
16K9.
17P64
18RC3
197X8
sort
creationdate20170621
titleHigh-Speed and Scalable Whole-Brain Imaging in Rodents and Primates
authorSeiriki, Kaoru ; Kasai, Atsushi ; Hashimoto, Takeshi ; Schulze, Wiebke ; Niu, Misaki ; Yamaguchi, Shun ; Nakazawa, Takanobu ; Inoue, Ken-ichi ; Uezono, Shiori ; Takada, Masahiko ; Naka, Yuichiro ; Igarashi, Hisato ; Tanuma, Masato ; Waschek, James A ; Ago, Yukio ; Tanaka, Kenji F ; Hayata-Takano, Atsuko ; Nagayasu, Kazuki ; Shintani, Norihito ; Hashimoto, Ryota ; Kunii, Yasuto ; Hino, Mizuki ; Matsumoto, Junya ; Yabe, Hirooki ; Nagai, Takeharu ; Fujita, Katsumasa ; Matsuda, Toshio ; Takuma, Kazuhiro ; Baba, Akemichi ; Hashimoto, Hitoshi
facets
frbrtype5
frbrgroupidcdi_FETCH-LOGICAL-1516t-36124df43678c6cbe6b6e2723e5f297b6526b398b0f20a57a02ce26252d8d6203
rsrctypearticles
prefilterarticles
languageeng
creationdate2017
topic
0Aged, 80 and over
1Animal models
2Animals
3Automation
4Brain
5Brain - anatomy & histology
6Brain - diagnostic imaging
7Callithrix
8cell distribution
9Female
10Fluorescence microscopy
11Gene expression
12High resolution
13human post-mortem brain
14Humans
15Image acquisition
16Image analysis
17Image processing
18Image Processing, Computer-Assisted - methods
19Image resolution
20Imaging
21Imaging systems
22Imaging, Three-Dimensional - methods
23Male
24Medical imaging
25Methods
26Mice
27Microscopy
28Microscopy - methods
29Microscopy, Fluorescence - methods
30Monkeys & apes
31Morphology
32Neurites
33Neuroimaging
34Neuroimaging - methods
35Neurons
36Neurosciences
37non-human primate brain
38Open source software
39Primates
40Rodents
41Sectioning
42Spatial discrimination
43Spatial resolution
44subcellular resolution
45Tomography - methods
46whole-brain imaging
toplevel
0peer_reviewed
1online_resources
creatorcontrib
0Seiriki, Kaoru
1Kasai, Atsushi
2Hashimoto, Takeshi
3Schulze, Wiebke
4Niu, Misaki
5Yamaguchi, Shun
6Nakazawa, Takanobu
7Inoue, Ken-ichi
8Uezono, Shiori
9Takada, Masahiko
10Naka, Yuichiro
11Igarashi, Hisato
12Tanuma, Masato
13Waschek, James A
14Ago, Yukio
15Tanaka, Kenji F
16Hayata-Takano, Atsuko
17Nagayasu, Kazuki
18Shintani, Norihito
19Hashimoto, Ryota
20Kunii, Yasuto
21Hino, Mizuki
22Matsumoto, Junya
23Yabe, Hirooki
24Nagai, Takeharu
25Fujita, Katsumasa
26Matsuda, Toshio
27Takuma, Kazuhiro
28Baba, Akemichi
29Hashimoto, Hitoshi
collection
0ScienceDirect Open Access Titles
1Elsevier:ScienceDirect:Open Access
2Medline
3MEDLINE
4MEDLINE (Ovid)
5MEDLINE
6MEDLINE
7PubMed
8CrossRef
9Academic OneFile (A&I only)
10Calcium & Calcified Tissue Abstracts
11Chemoreception Abstracts
12Neurosciences Abstracts
13Technology Research Database
14Engineering Research Database
15ProQuest Health & Medical Complete (Alumni)
16Biotechnology and BioEngineering Abstracts
17Genetics Abstracts
18MEDLINE - Academic
jtitleNeuron (Cambridge, Mass.)
delivery
delcategoryRemote Search Resource
fulltextfulltext
addata
au
0Seiriki, Kaoru
1Kasai, Atsushi
2Hashimoto, Takeshi
3Schulze, Wiebke
4Niu, Misaki
5Yamaguchi, Shun
6Nakazawa, Takanobu
7Inoue, Ken-ichi
8Uezono, Shiori
9Takada, Masahiko
10Naka, Yuichiro
11Igarashi, Hisato
12Tanuma, Masato
13Waschek, James A
14Ago, Yukio
15Tanaka, Kenji F
16Hayata-Takano, Atsuko
17Nagayasu, Kazuki
18Shintani, Norihito
19Hashimoto, Ryota
20Kunii, Yasuto
21Hino, Mizuki
22Matsumoto, Junya
23Yabe, Hirooki
24Nagai, Takeharu
25Fujita, Katsumasa
26Matsuda, Toshio
27Takuma, Kazuhiro
28Baba, Akemichi
29Hashimoto, Hitoshi
formatjournal
genrearticle
ristypeJOUR
atitleHigh-Speed and Scalable Whole-Brain Imaging in Rodents and Primates
jtitleNeuron (Cambridge, Mass.)
addtitleNeuron
date2017-06-21
risdate2017
volume94
issue6
spage1085
epage1100.e6
pages1085-1100.e6
issn0896-6273
eissn1097-4199
abstractSubcellular resolution imaging of the whole brain and subsequent image analysis are prerequisites for understanding anatomical and functional brain networks. Here, we have developed a very high-speed serial-sectioning imaging system named FAST (block-face serial microscopy tomography), which acquires high-resolution images of a whole mouse brain in a speed range comparable to that of light-sheet fluorescence microscopy. FAST enables complete visualization of the brain at a resolution sufficient to resolve all cells and their subcellular structures. FAST renders unbiased quantitative group comparisons of normal and disease model brain cells for the whole brain at a high spatial resolution. Furthermore, FAST is highly scalable to non-human primate brains and human postmortem brain tissues, and can visualize neuronal projections in a whole adult marmoset brain. Thus, FAST provides new opportunities for global approaches that will allow for a better understanding of brain systems in multiple animal models and in human diseases. •FAST acquires whole-brain subcellular resolution images with unprecedented speed•FAST is scalable to non-human primate brains and human postmortem brain tissues•FAST renders unbiased group comparisons of the whole-brain high-resolution images Seiriki et al. developed a very high-speed serial-sectioning imaging system named FAST that allows whole-brain imaging at a spatial resolution to image all brain cells and long-range neuronal projections in experimental animal models and facilitates animal-to-human translational research.
copUnited States
pubElsevier Inc
pmid28641108
doi10.1016/j.neuron.2017.05.017
oafree_for_read