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Ischemic or Nonischemic Functional Mitral Regurgitation and Outcomes in Patients With Acute Decompensated Heart Failure With Preserved or Reduced Ejection Fraction

The aim of this study was to evaluate the association of functional mitral regurgitation (FMR), preserved or reduced ejection fraction (EF), and ischemic or nonischemic origin with outcomes in patients discharged alive after hospitalization for acute decompensated heart failure (HF). Of the 4,842 pa... Full description

Journal Title: The American journal of cardiology 2017-09-01, Vol.120 (5), p.809-816
Main Author: Kajimoto, Katsuya
Other Authors: Minami, Yuichiro , Sato, Naoki , Sato, Naoki , Munakata, Ryo , Minami, Yuichiro , Yumino, Dai , Mizuno, Masayuki , Kawada, Erisa , Ozaki, Yuri , Nakao, Koichi , Sawamura, Tadashi , Ishiki, Ryoji , Fujinaga, Hiroyuki , Yamamoto, Takashi , Hata, Noritake , Nozaki, Ayaka , Kawanaka, Hidekazu , Sato, Yukihito , Oiwa, Hitoshi , Matsumoto, Tomoaki , Yoshida, Daisuke , Kato, Nobuo , Shimizu, Nobuyuki , Chinen, Toshiya , Kikuchi, Tatsuro , Nishikido, Toshiyuki , Yamashita, Tatsuya , Hirono, Akitoshi , Mitsudo, Kazuaki , Kadota, Kazushige , Makita, Noriko , Kawabata, Masaaki , Fujii, Kenichi , Kobayashi, Shigeki , Moriuchi, Ikuo , Murakami, Tatsuaki , Shimada, Yoshifumi , Fukuoka, Yoshitomo , Takata, Yoshifumi , Miyagi, Manabu , Tanaka, Nobuhiro , Yamashina, Akira , Sudo, Shinji , Shimamura, Koichi , Nagashima, Michitaka , Kaneda, Tomoya , Ueda, Kosei , Fujii, Shinya , Yagi, Masahiro , Takaki, Jyunko , Toyama, Takuji , Oka, Toshiaki , Naruko, Takahiko , Abe, Yukio , Uematsu, Shoko , Sakamoto, Takafumi , Koide, Yuji , Maemura, Koji , Yoshihisa, Akiomi , Kinugasa, Yoshiharu , Ishida, Katsunori , Sugihara, Shinobu , Yanagihara, Kiyotaka , Takeuchi, Toshiharu , Okada, Motoi , Sakai, Tetsuo , Minoura, Yoshino , Sato, Takatoshi , Yokota, Yuya , Komuro, Issei , Otsu, Kinya , Asano, Yoshihiro , Kajimoto, Katsuya , Kashiwase, Kazunori , Ueda, Yasunori , Komaki, Tomo , Nakajima, Yoshie , Ikeda, Yoshifimi , Tamaki, Toru , Sakuragawa, Koichiro , Kohsaka, Shun , Ando, Shin-ichi , Kadokami, Toshiaki , Ishida, Eiko , Higuchi, Yoshiharu , Ohte, Nobuyuki , Shiba, Nobuyuki , Nochioka, Kotaro , Shimokawa, Hiroaki , Koga, Tokushi , Kida, Keisuke , Kamisihima, Kazuho , Nakamura, Makiko , Touma, Takashi , Shinjo, Osamu , Nishimura, Yoshioki , Uchida, Takahiro , Amitani, Ken-ichi , Sato, Naoki
Format: Electronic Article Electronic Article
Language: English
Subjects:
Publisher: United States: Elsevier Inc
ID: ISSN: 0002-9149
Link: https://www.ncbi.nlm.nih.gov/pubmed/28705383
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recordid: cdi_proquest_miscellaneous_1920194560
title: Ischemic or Nonischemic Functional Mitral Regurgitation and Outcomes in Patients With Acute Decompensated Heart Failure With Preserved or Reduced Ejection Fraction
format: Article
creator:
  • Kajimoto, Katsuya
  • Minami, Yuichiro
  • Sato, Naoki
  • Sato, Naoki
  • Munakata, Ryo
  • Minami, Yuichiro
  • Yumino, Dai
  • Mizuno, Masayuki
  • Kawada, Erisa
  • Ozaki, Yuri
  • Nakao, Koichi
  • Sawamura, Tadashi
  • Ishiki, Ryoji
  • Fujinaga, Hiroyuki
  • Yamamoto, Takashi
  • Hata, Noritake
  • Nozaki, Ayaka
  • Kawanaka, Hidekazu
  • Sato, Yukihito
  • Oiwa, Hitoshi
  • Matsumoto, Tomoaki
  • Yoshida, Daisuke
  • Kato, Nobuo
  • Shimizu, Nobuyuki
  • Chinen, Toshiya
  • Kikuchi, Tatsuro
  • Nishikido, Toshiyuki
  • Yamashita, Tatsuya
  • Hirono, Akitoshi
  • Mitsudo, Kazuaki
  • Kadota, Kazushige
  • Makita, Noriko
  • Kawabata, Masaaki
  • Fujii, Kenichi
  • Kobayashi, Shigeki
  • Moriuchi, Ikuo
  • Murakami, Tatsuaki
  • Shimada, Yoshifumi
  • Fukuoka, Yoshitomo
  • Takata, Yoshifumi
  • Miyagi, Manabu
  • Tanaka, Nobuhiro
  • Yamashina, Akira
  • Sudo, Shinji
  • Shimamura, Koichi
  • Nagashima, Michitaka
  • Kaneda, Tomoya
  • Ueda, Kosei
  • Fujii, Shinya
  • Yagi, Masahiro
  • Takaki, Jyunko
  • Toyama, Takuji
  • Oka, Toshiaki
  • Naruko, Takahiko
  • Abe, Yukio
  • Uematsu, Shoko
  • Sakamoto, Takafumi
  • Koide, Yuji
  • Maemura, Koji
  • Yoshihisa, Akiomi
  • Kinugasa, Yoshiharu
  • Ishida, Katsunori
  • Sugihara, Shinobu
  • Yanagihara, Kiyotaka
  • Takeuchi, Toshiharu
  • Okada, Motoi
  • Sakai, Tetsuo
  • Minoura, Yoshino
  • Sato, Takatoshi
  • Yokota, Yuya
  • Komuro, Issei
  • Otsu, Kinya
  • Asano, Yoshihiro
  • Kajimoto, Katsuya
  • Kashiwase, Kazunori
  • Ueda, Yasunori
  • Komaki, Tomo
  • Nakajima, Yoshie
  • Ikeda, Yoshifimi
  • Tamaki, Toru
  • Sakuragawa, Koichiro
  • Kohsaka, Shun
  • Ando, Shin-ichi
  • Kadokami, Toshiaki
  • Ishida, Eiko
  • Higuchi, Yoshiharu
  • Ohte, Nobuyuki
  • Shiba, Nobuyuki
  • Nochioka, Kotaro
  • Shimokawa, Hiroaki
  • Koga, Tokushi
  • Kida, Keisuke
  • Kamisihima, Kazuho
  • Nakamura, Makiko
  • Touma, Takashi
  • Shinjo, Osamu
  • Nishimura, Yoshioki
  • Uchida, Takahiro
  • Amitani, Ken-ichi
  • Sato, Naoki
subjects:
  • Abridged Index Medicus
  • Acute coronary syndromes
  • Acute Disease
  • Analysis
  • Cardiac patients
  • Cardiomyopathy
  • Cardiovascular disease
  • Care and treatment
  • Cause of Death - trends
  • Color
  • Confidence intervals
  • Disorders
  • Echocardiography, Doppler
  • Female
  • Health risk assessment
  • Heart attacks
  • Heart diseases
  • Heart failure
  • Heart Failure - complications
  • Heart Failure - mortality
  • Heart Failure - physiopathology
  • Heart Ventricles - diagnostic imaging
  • Heart Ventricles - physiopathology
  • Hospitalization
  • Humans
  • Hypertension
  • Incidence
  • Ischemia
  • Japan - epidemiology
  • Male
  • Mitral valve insufficiency
  • Mitral Valve Insufficiency - diagnosis
  • Mitral Valve Insufficiency - epidemiology
  • Mitral Valve Insufficiency - etiology
  • Mortality
  • Myocardial Ischemia - complications
  • Myocardial Ischemia - diagnosis
  • Myocardial Ischemia - physiopathology
  • Patient outcomes
  • Patients
  • Prospective Studies
  • Registries
  • Regurgitation
  • Severity of Illness Index
  • Stroke Volume - physiology
  • Survival Rate - trends
  • Ultrasonic imaging
  • Ventricular Function, Left - physiology
ispartof: The American journal of cardiology, 2017-09-01, Vol.120 (5), p.809-816
description: The aim of this study was to evaluate the association of functional mitral regurgitation (FMR), preserved or reduced ejection fraction (EF), and ischemic or nonischemic origin with outcomes in patients discharged alive after hospitalization for acute decompensated heart failure (HF). Of the 4,842 patients enrolled in the Acute Decompensated Heart Failure Syndromes (ATTEND) registry, 3,357 patients were evaluated to assess the association of FMR, preserved or reduced EF, and ischemic or nonischemic origin with the primary end point (all-cause death and readmission for HF after discharge). At the time of discharge, FMR was assessed semiquantitatively (classified as none, mild, or moderate to severe) by color Doppler analysis of the regurgitant jet area. According to multivariable analysis, in the ischemic group, either mild or moderate to severe FMR in patients with a preserved EF had a significantly higher risk of the primary end point than patients without FMR (hazard ratio [HR] 1.60; 95% confidence interval [CI] 1.12 to 2.29; p = 0.010 and HR 1.98; 95% CI 1.30 to 3.01; p = 0.001, respectively). In patients with reduced EF with an ischemic origin, only moderate to severe FMR was associated with a significantly higher risk of the primary end point (HR 1.67; 95% CI 1.11 to 2.50; p = 0.014). In the nonischemic group, there was no significant association between FMR and the primary end point in patients with either a preserved or reduced EF. In conclusion, among patients with acute decompensated HF with a preserved or reduced EF, the association of FMR with adverse outcomes may differ between patients who had an ischemic or nonischemic origin of HF.
language: eng
source:
identifier: ISSN: 0002-9149
fulltext: no_fulltext
issn:
  • 0002-9149
  • 1879-1913
url: Link


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titleIschemic or Nonischemic Functional Mitral Regurgitation and Outcomes in Patients With Acute Decompensated Heart Failure With Preserved or Reduced Ejection Fraction
creatorKajimoto, Katsuya ; Minami, Yuichiro ; Sato, Naoki ; Sato, Naoki ; Munakata, Ryo ; Minami, Yuichiro ; Yumino, Dai ; Mizuno, Masayuki ; Kawada, Erisa ; Ozaki, Yuri ; Nakao, Koichi ; Sawamura, Tadashi ; Ishiki, Ryoji ; Fujinaga, Hiroyuki ; Yamamoto, Takashi ; Hata, Noritake ; Nozaki, Ayaka ; Kawanaka, Hidekazu ; Sato, Yukihito ; Oiwa, Hitoshi ; Matsumoto, Tomoaki ; Yoshida, Daisuke ; Kato, Nobuo ; Shimizu, Nobuyuki ; Chinen, Toshiya ; Kikuchi, Tatsuro ; Nishikido, Toshiyuki ; Yamashita, Tatsuya ; Hirono, Akitoshi ; Mitsudo, Kazuaki ; Kadota, Kazushige ; Makita, Noriko ; Kawabata, Masaaki ; Fujii, Kenichi ; Kobayashi, Shigeki ; Moriuchi, Ikuo ; Murakami, Tatsuaki ; Shimada, Yoshifumi ; Fukuoka, Yoshitomo ; Takata, Yoshifumi ; Miyagi, Manabu ; Tanaka, Nobuhiro ; Yamashina, Akira ; Sudo, Shinji ; Shimamura, Koichi ; Nagashima, Michitaka ; Kaneda, Tomoya ; Ueda, Kosei ; Fujii, Shinya ; Yagi, Masahiro ; Takaki, Jyunko ; Toyama, Takuji ; Oka, Toshiaki ; Naruko, Takahiko ; Abe, Yukio ; Uematsu, Shoko ; Sakamoto, Takafumi ; Koide, Yuji ; Maemura, Koji ; Yoshihisa, Akiomi ; Kinugasa, Yoshiharu ; Ishida, Katsunori ; Sugihara, Shinobu ; Yanagihara, Kiyotaka ; Takeuchi, Toshiharu ; Okada, Motoi ; Sakai, Tetsuo ; Minoura, Yoshino ; Sato, Takatoshi ; Yokota, Yuya ; Komuro, Issei ; Otsu, Kinya ; Asano, Yoshihiro ; Kajimoto, Katsuya ; Kashiwase, Kazunori ; Ueda, Yasunori ; Komaki, Tomo ; Nakajima, Yoshie ; Ikeda, Yoshifimi ; Tamaki, Toru ; Sakuragawa, Koichiro ; Kohsaka, Shun ; Ando, Shin-ichi ; Kadokami, Toshiaki ; Ishida, Eiko ; Higuchi, Yoshiharu ; Ohte, Nobuyuki ; Shiba, Nobuyuki ; Nochioka, Kotaro ; Shimokawa, Hiroaki ; Koga, Tokushi ; Kida, Keisuke ; Kamisihima, Kazuho ; Nakamura, Makiko ; Touma, Takashi ; Shinjo, Osamu ; Nishimura, Yoshioki ; Uchida, Takahiro ; Amitani, Ken-ichi ; Sato, Naoki
creatorcontribKajimoto, Katsuya ; Minami, Yuichiro ; Sato, Naoki ; Sato, Naoki ; Munakata, Ryo ; Minami, Yuichiro ; Yumino, Dai ; Mizuno, Masayuki ; Kawada, Erisa ; Ozaki, Yuri ; Nakao, Koichi ; Sawamura, Tadashi ; Ishiki, Ryoji ; Fujinaga, Hiroyuki ; Yamamoto, Takashi ; Hata, Noritake ; Nozaki, Ayaka ; Kawanaka, Hidekazu ; Sato, Yukihito ; Oiwa, Hitoshi ; Matsumoto, Tomoaki ; Yoshida, Daisuke ; Kato, Nobuo ; Shimizu, Nobuyuki ; Chinen, Toshiya ; Kikuchi, Tatsuro ; Nishikido, Toshiyuki ; Yamashita, Tatsuya ; Hirono, Akitoshi ; Mitsudo, Kazuaki ; Kadota, Kazushige ; Makita, Noriko ; Kawabata, Masaaki ; Fujii, Kenichi ; Kobayashi, Shigeki ; Moriuchi, Ikuo ; Murakami, Tatsuaki ; Shimada, Yoshifumi ; Fukuoka, Yoshitomo ; Takata, Yoshifumi ; Miyagi, Manabu ; Tanaka, Nobuhiro ; Yamashina, Akira ; Sudo, Shinji ; Shimamura, Koichi ; Nagashima, Michitaka ; Kaneda, Tomoya ; Ueda, Kosei ; Fujii, Shinya ; Yagi, Masahiro ; Takaki, Jyunko ; Toyama, Takuji ; Oka, Toshiaki ; Naruko, Takahiko ; Abe, Yukio ; Uematsu, Shoko ; Sakamoto, Takafumi ; Koide, Yuji ; Maemura, Koji ; Yoshihisa, Akiomi ; Kinugasa, Yoshiharu ; Ishida, Katsunori ; Sugihara, Shinobu ; Yanagihara, Kiyotaka ; Takeuchi, Toshiharu ; Okada, Motoi ; Sakai, Tetsuo ; Minoura, Yoshino ; Sato, Takatoshi ; Yokota, Yuya ; Komuro, Issei ; Otsu, Kinya ; Asano, Yoshihiro ; Kajimoto, Katsuya ; Kashiwase, Kazunori ; Ueda, Yasunori ; Komaki, Tomo ; Nakajima, Yoshie ; Ikeda, Yoshifimi ; Tamaki, Toru ; Sakuragawa, Koichiro ; Kohsaka, Shun ; Ando, Shin-ichi ; Kadokami, Toshiaki ; Ishida, Eiko ; Higuchi, Yoshiharu ; Ohte, Nobuyuki ; Shiba, Nobuyuki ; Nochioka, Kotaro ; Shimokawa, Hiroaki ; Koga, Tokushi ; Kida, Keisuke ; Kamisihima, Kazuho ; Nakamura, Makiko ; Touma, Takashi ; Shinjo, Osamu ; Nishimura, Yoshioki ; Uchida, Takahiro ; Amitani, Ken-ichi ; Sato, Naoki ; investigators of the Acute Decompensated Heart Failure Syndromes (ATTEND) registry
descriptionThe aim of this study was to evaluate the association of functional mitral regurgitation (FMR), preserved or reduced ejection fraction (EF), and ischemic or nonischemic origin with outcomes in patients discharged alive after hospitalization for acute decompensated heart failure (HF). Of the 4,842 patients enrolled in the Acute Decompensated Heart Failure Syndromes (ATTEND) registry, 3,357 patients were evaluated to assess the association of FMR, preserved or reduced EF, and ischemic or nonischemic origin with the primary end point (all-cause death and readmission for HF after discharge). At the time of discharge, FMR was assessed semiquantitatively (classified as none, mild, or moderate to severe) by color Doppler analysis of the regurgitant jet area. According to multivariable analysis, in the ischemic group, either mild or moderate to severe FMR in patients with a preserved EF had a significantly higher risk of the primary end point than patients without FMR (hazard ratio [HR] 1.60; 95% confidence interval [CI] 1.12 to 2.29; p = 0.010 and HR 1.98; 95% CI 1.30 to 3.01; p = 0.001, respectively). In patients with reduced EF with an ischemic origin, only moderate to severe FMR was associated with a significantly higher risk of the primary end point (HR 1.67; 95% CI 1.11 to 2.50; p = 0.014). In the nonischemic group, there was no significant association between FMR and the primary end point in patients with either a preserved or reduced EF. In conclusion, among patients with acute decompensated HF with a preserved or reduced EF, the association of FMR with adverse outcomes may differ between patients who had an ischemic or nonischemic origin of HF.
identifier
0ISSN: 0002-9149
1EISSN: 1879-1913
2DOI: 10.1016/j.amjcard.2017.05.051
3PMID: 28705383
languageeng
publisherUnited States: Elsevier Inc
subjectAbridged Index Medicus ; Acute coronary syndromes ; Acute Disease ; Analysis ; Cardiac patients ; Cardiomyopathy ; Cardiovascular disease ; Care and treatment ; Cause of Death - trends ; Color ; Confidence intervals ; Disorders ; Echocardiography, Doppler ; Female ; Health risk assessment ; Heart attacks ; Heart diseases ; Heart failure ; Heart Failure - complications ; Heart Failure - mortality ; Heart Failure - physiopathology ; Heart Ventricles - diagnostic imaging ; Heart Ventricles - physiopathology ; Hospitalization ; Humans ; Hypertension ; Incidence ; Ischemia ; Japan - epidemiology ; Male ; Mitral valve insufficiency ; Mitral Valve Insufficiency - diagnosis ; Mitral Valve Insufficiency - epidemiology ; Mitral Valve Insufficiency - etiology ; Mortality ; Myocardial Ischemia - complications ; Myocardial Ischemia - diagnosis ; Myocardial Ischemia - physiopathology ; Patient outcomes ; Patients ; Prospective Studies ; Registries ; Regurgitation ; Severity of Illness Index ; Stroke Volume - physiology ; Survival Rate - trends ; Ultrasonic imaging ; Ventricular Function, Left - physiology
ispartofThe American journal of cardiology, 2017-09-01, Vol.120 (5), p.809-816
rights
02017 Elsevier Inc.
1Copyright © 2017 Elsevier Inc. All rights reserved.
2COPYRIGHT 2017 Elsevier B.V.
3Copyright Elsevier Sequoia S.A. Sep 1, 2017
lds50peer_reviewed
citesFETCH-LOGICAL-c371t-8f93cf8814b3eb200ad20455c73a36fdb58a31cd12d7f4a9b7131d6cf22511800
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creatorcontrib
0Kajimoto, Katsuya
1Minami, Yuichiro
2Sato, Naoki
3Sato, Naoki
4Munakata, Ryo
5Minami, Yuichiro
6Yumino, Dai
7Mizuno, Masayuki
8Kawada, Erisa
9Ozaki, Yuri
10Nakao, Koichi
11Sawamura, Tadashi
12Ishiki, Ryoji
13Fujinaga, Hiroyuki
14Yamamoto, Takashi
15Hata, Noritake
16Nozaki, Ayaka
17Kawanaka, Hidekazu
18Sato, Yukihito
19Oiwa, Hitoshi
20Matsumoto, Tomoaki
21Yoshida, Daisuke
22Kato, Nobuo
23Shimizu, Nobuyuki
24Chinen, Toshiya
25Kikuchi, Tatsuro
26Nishikido, Toshiyuki
27Yamashita, Tatsuya
28Hirono, Akitoshi
29Mitsudo, Kazuaki
30Kadota, Kazushige
31Makita, Noriko
32Kawabata, Masaaki
33Fujii, Kenichi
34Kobayashi, Shigeki
35Moriuchi, Ikuo
36Murakami, Tatsuaki
37Shimada, Yoshifumi
38Fukuoka, Yoshitomo
39Takata, Yoshifumi
40Miyagi, Manabu
41Tanaka, Nobuhiro
42Yamashina, Akira
43Sudo, Shinji
44Shimamura, Koichi
45Nagashima, Michitaka
46Kaneda, Tomoya
47Ueda, Kosei
48Fujii, Shinya
49Yagi, Masahiro
50Takaki, Jyunko
51Toyama, Takuji
52Oka, Toshiaki
53Naruko, Takahiko
54Abe, Yukio
55Uematsu, Shoko
56Sakamoto, Takafumi
57Koide, Yuji
58Maemura, Koji
59Yoshihisa, Akiomi
60Kinugasa, Yoshiharu
61Ishida, Katsunori
62Sugihara, Shinobu
63Yanagihara, Kiyotaka
64Takeuchi, Toshiharu
65Okada, Motoi
66Sakai, Tetsuo
67Minoura, Yoshino
68Sato, Takatoshi
69Yokota, Yuya
70Komuro, Issei
71Otsu, Kinya
72Asano, Yoshihiro
73Kajimoto, Katsuya
74Kashiwase, Kazunori
75Ueda, Yasunori
76Komaki, Tomo
77Nakajima, Yoshie
78Ikeda, Yoshifimi
79Tamaki, Toru
80Sakuragawa, Koichiro
81Kohsaka, Shun
82Ando, Shin-ichi
83Kadokami, Toshiaki
84Ishida, Eiko
85Higuchi, Yoshiharu
86Ohte, Nobuyuki
87Shiba, Nobuyuki
88Nochioka, Kotaro
89Shimokawa, Hiroaki
90Koga, Tokushi
91Kida, Keisuke
92Kamisihima, Kazuho
93Nakamura, Makiko
94Touma, Takashi
95Shinjo, Osamu
96Nishimura, Yoshioki
97Uchida, Takahiro
98Amitani, Ken-ichi
99Sato, Naoki
100investigators of the Acute Decompensated Heart Failure Syndromes (ATTEND) registry
title
0Ischemic or Nonischemic Functional Mitral Regurgitation and Outcomes in Patients With Acute Decompensated Heart Failure With Preserved or Reduced Ejection Fraction
1The American journal of cardiology
addtitleAm J Cardiol
descriptionThe aim of this study was to evaluate the association of functional mitral regurgitation (FMR), preserved or reduced ejection fraction (EF), and ischemic or nonischemic origin with outcomes in patients discharged alive after hospitalization for acute decompensated heart failure (HF). Of the 4,842 patients enrolled in the Acute Decompensated Heart Failure Syndromes (ATTEND) registry, 3,357 patients were evaluated to assess the association of FMR, preserved or reduced EF, and ischemic or nonischemic origin with the primary end point (all-cause death and readmission for HF after discharge). At the time of discharge, FMR was assessed semiquantitatively (classified as none, mild, or moderate to severe) by color Doppler analysis of the regurgitant jet area. According to multivariable analysis, in the ischemic group, either mild or moderate to severe FMR in patients with a preserved EF had a significantly higher risk of the primary end point than patients without FMR (hazard ratio [HR] 1.60; 95% confidence interval [CI] 1.12 to 2.29; p = 0.010 and HR 1.98; 95% CI 1.30 to 3.01; p = 0.001, respectively). In patients with reduced EF with an ischemic origin, only moderate to severe FMR was associated with a significantly higher risk of the primary end point (HR 1.67; 95% CI 1.11 to 2.50; p = 0.014). In the nonischemic group, there was no significant association between FMR and the primary end point in patients with either a preserved or reduced EF. In conclusion, among patients with acute decompensated HF with a preserved or reduced EF, the association of FMR with adverse outcomes may differ between patients who had an ischemic or nonischemic origin of HF.
subject
0Abridged Index Medicus
1Acute coronary syndromes
2Acute Disease
3Analysis
4Cardiac patients
5Cardiomyopathy
6Cardiovascular disease
7Care and treatment
8Cause of Death - trends
9Color
10Confidence intervals
11Disorders
12Echocardiography, Doppler
13Female
14Health risk assessment
15Heart attacks
16Heart diseases
17Heart failure
18Heart Failure - complications
19Heart Failure - mortality
20Heart Failure - physiopathology
21Heart Ventricles - diagnostic imaging
22Heart Ventricles - physiopathology
23Hospitalization
24Humans
25Hypertension
26Incidence
27Ischemia
28Japan - epidemiology
29Male
30Mitral valve insufficiency
31Mitral Valve Insufficiency - diagnosis
32Mitral Valve Insufficiency - epidemiology
33Mitral Valve Insufficiency - etiology
34Mortality
35Myocardial Ischemia - complications
36Myocardial Ischemia - diagnosis
37Myocardial Ischemia - physiopathology
38Patient outcomes
39Patients
40Prospective Studies
41Registries
42Regurgitation
43Severity of Illness Index
44Stroke Volume - physiology
45Survival Rate - trends
46Ultrasonic imaging
47Ventricular Function, Left - physiology
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00002-9149
11879-1913
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startdate20170901
enddate20170901
creator
0Kajimoto, Katsuya
1Minami, Yuichiro
2Sato, Naoki
3Sato, Naoki
4Munakata, Ryo
5Minami, Yuichiro
6Yumino, Dai
7Mizuno, Masayuki
8Kawada, Erisa
9Ozaki, Yuri
10Nakao, Koichi
11Sawamura, Tadashi
12Ishiki, Ryoji
13Fujinaga, Hiroyuki
14Yamamoto, Takashi
15Hata, Noritake
16Nozaki, Ayaka
17Kawanaka, Hidekazu
18Sato, Yukihito
19Oiwa, Hitoshi
20Matsumoto, Tomoaki
21Yoshida, Daisuke
22Kato, Nobuo
23Shimizu, Nobuyuki
24Chinen, Toshiya
25Kikuchi, Tatsuro
26Nishikido, Toshiyuki
27Yamashita, Tatsuya
28Hirono, Akitoshi
29Mitsudo, Kazuaki
30Kadota, Kazushige
31Makita, Noriko
32Kawabata, Masaaki
33Fujii, Kenichi
34Kobayashi, Shigeki
35Moriuchi, Ikuo
36Murakami, Tatsuaki
37Shimada, Yoshifumi
38Fukuoka, Yoshitomo
39Takata, Yoshifumi
40Miyagi, Manabu
41Tanaka, Nobuhiro
42Yamashina, Akira
43Sudo, Shinji
44Shimamura, Koichi
45Nagashima, Michitaka
46Kaneda, Tomoya
47Ueda, Kosei
48Fujii, Shinya
49Yagi, Masahiro
50Takaki, Jyunko
51Toyama, Takuji
52Oka, Toshiaki
53Naruko, Takahiko
54Abe, Yukio
55Uematsu, Shoko
56Sakamoto, Takafumi
57Koide, Yuji
58Maemura, Koji
59Yoshihisa, Akiomi
60Kinugasa, Yoshiharu
61Ishida, Katsunori
62Sugihara, Shinobu
63Yanagihara, Kiyotaka
64Takeuchi, Toshiharu
65Okada, Motoi
66Sakai, Tetsuo
67Minoura, Yoshino
68Sato, Takatoshi
69Yokota, Yuya
70Komuro, Issei
71Otsu, Kinya
72Asano, Yoshihiro
73Kajimoto, Katsuya
74Kashiwase, Kazunori
75Ueda, Yasunori
76Komaki, Tomo
77Nakajima, Yoshie
78Ikeda, Yoshifimi
79Tamaki, Toru
80Sakuragawa, Koichiro
81Kohsaka, Shun
82Ando, Shin-ichi
83Kadokami, Toshiaki
84Ishida, Eiko
85Higuchi, Yoshiharu
86Ohte, Nobuyuki
87Shiba, Nobuyuki
88Nochioka, Kotaro
89Shimokawa, Hiroaki
90Koga, Tokushi
91Kida, Keisuke
92Kamisihima, Kazuho
93Nakamura, Makiko
94Touma, Takashi
95Shinjo, Osamu
96Nishimura, Yoshioki
97Uchida, Takahiro
98Amitani, Ken-ichi
99Sato, Naoki
general
0Elsevier Inc
1Elsevier B.V
2Elsevier Limited
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creationdate20170901
titleIschemic or Nonischemic Functional Mitral Regurgitation and Outcomes in Patients With Acute Decompensated Heart Failure With Preserved or Reduced Ejection Fraction
authorKajimoto, Katsuya ; Minami, Yuichiro ; Sato, Naoki ; Sato, Naoki ; Munakata, Ryo ; Minami, Yuichiro ; Yumino, Dai ; Mizuno, Masayuki ; Kawada, Erisa ; Ozaki, Yuri ; Nakao, Koichi ; Sawamura, Tadashi ; Ishiki, Ryoji ; Fujinaga, Hiroyuki ; Yamamoto, Takashi ; Hata, Noritake ; Nozaki, Ayaka ; Kawanaka, Hidekazu ; Sato, Yukihito ; Oiwa, Hitoshi ; Matsumoto, Tomoaki ; Yoshida, Daisuke ; Kato, Nobuo ; Shimizu, Nobuyuki ; Chinen, Toshiya ; Kikuchi, Tatsuro ; Nishikido, Toshiyuki ; Yamashita, Tatsuya ; Hirono, Akitoshi ; Mitsudo, Kazuaki ; Kadota, Kazushige ; Makita, Noriko ; Kawabata, Masaaki ; Fujii, Kenichi ; Kobayashi, Shigeki ; Moriuchi, Ikuo ; Murakami, Tatsuaki ; Shimada, Yoshifumi ; Fukuoka, Yoshitomo ; Takata, Yoshifumi ; Miyagi, Manabu ; Tanaka, Nobuhiro ; Yamashina, Akira ; Sudo, Shinji ; Shimamura, Koichi ; Nagashima, Michitaka ; Kaneda, Tomoya ; Ueda, Kosei ; Fujii, Shinya ; Yagi, Masahiro ; Takaki, Jyunko ; Toyama, Takuji ; Oka, Toshiaki ; Naruko, Takahiko ; Abe, Yukio ; Uematsu, Shoko ; Sakamoto, Takafumi ; Koide, Yuji ; Maemura, Koji ; Yoshihisa, Akiomi ; Kinugasa, Yoshiharu ; Ishida, Katsunori ; Sugihara, Shinobu ; Yanagihara, Kiyotaka ; Takeuchi, Toshiharu ; Okada, Motoi ; Sakai, Tetsuo ; Minoura, Yoshino ; Sato, Takatoshi ; Yokota, Yuya ; Komuro, Issei ; Otsu, Kinya ; Asano, Yoshihiro ; Kajimoto, Katsuya ; Kashiwase, Kazunori ; Ueda, Yasunori ; Komaki, Tomo ; Nakajima, Yoshie ; Ikeda, Yoshifimi ; Tamaki, Toru ; Sakuragawa, Koichiro ; Kohsaka, Shun ; Ando, Shin-ichi ; Kadokami, Toshiaki ; Ishida, Eiko ; Higuchi, Yoshiharu ; Ohte, Nobuyuki ; Shiba, Nobuyuki ; Nochioka, Kotaro ; Shimokawa, Hiroaki ; Koga, Tokushi ; Kida, Keisuke ; Kamisihima, Kazuho ; Nakamura, Makiko ; Touma, Takashi ; Shinjo, Osamu ; Nishimura, Yoshioki ; Uchida, Takahiro ; Amitani, Ken-ichi ; Sato, Naoki
facets
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frbrgroupidcdi_FETCH-LOGICAL-c371t-8f93cf8814b3eb200ad20455c73a36fdb58a31cd12d7f4a9b7131d6cf22511800
rsrctypearticles
prefilterarticles
languageeng
creationdate2017
topic
0Abridged Index Medicus
1Acute coronary syndromes
2Acute Disease
3Analysis
4Cardiac patients
5Cardiomyopathy
6Cardiovascular disease
7Care and treatment
8Cause of Death - trends
9Color
10Confidence intervals
11Disorders
12Echocardiography, Doppler
13Female
14Health risk assessment
15Heart attacks
16Heart diseases
17Heart failure
18Heart Failure - complications
19Heart Failure - mortality
20Heart Failure - physiopathology
21Heart Ventricles - diagnostic imaging
22Heart Ventricles - physiopathology
23Hospitalization
24Humans
25Hypertension
26Incidence
27Ischemia
28Japan - epidemiology
29Male
30Mitral valve insufficiency
31Mitral Valve Insufficiency - diagnosis
32Mitral Valve Insufficiency - epidemiology
33Mitral Valve Insufficiency - etiology
34Mortality
35Myocardial Ischemia - complications
36Myocardial Ischemia - diagnosis
37Myocardial Ischemia - physiopathology
38Patient outcomes
39Patients
40Prospective Studies
41Registries
42Regurgitation
43Severity of Illness Index
44Stroke Volume - physiology
45Survival Rate - trends
46Ultrasonic imaging
47Ventricular Function, Left - physiology
toplevelpeer_reviewed
creatorcontrib
0Kajimoto, Katsuya
1Minami, Yuichiro
2Sato, Naoki
3Sato, Naoki
4Munakata, Ryo
5Minami, Yuichiro
6Yumino, Dai
7Mizuno, Masayuki
8Kawada, Erisa
9Ozaki, Yuri
10Nakao, Koichi
11Sawamura, Tadashi
12Ishiki, Ryoji
13Fujinaga, Hiroyuki
14Yamamoto, Takashi
15Hata, Noritake
16Nozaki, Ayaka
17Kawanaka, Hidekazu
18Sato, Yukihito
19Oiwa, Hitoshi
20Matsumoto, Tomoaki
21Yoshida, Daisuke
22Kato, Nobuo
23Shimizu, Nobuyuki
24Chinen, Toshiya
25Kikuchi, Tatsuro
26Nishikido, Toshiyuki
27Yamashita, Tatsuya
28Hirono, Akitoshi
29Mitsudo, Kazuaki
30Kadota, Kazushige
31Makita, Noriko
32Kawabata, Masaaki
33Fujii, Kenichi
34Kobayashi, Shigeki
35Moriuchi, Ikuo
36Murakami, Tatsuaki
37Shimada, Yoshifumi
38Fukuoka, Yoshitomo
39Takata, Yoshifumi
40Miyagi, Manabu
41Tanaka, Nobuhiro
42Yamashina, Akira
43Sudo, Shinji
44Shimamura, Koichi
45Nagashima, Michitaka
46Kaneda, Tomoya
47Ueda, Kosei
48Fujii, Shinya
49Yagi, Masahiro
50Takaki, Jyunko
51Toyama, Takuji
52Oka, Toshiaki
53Naruko, Takahiko
54Abe, Yukio
55Uematsu, Shoko
56Sakamoto, Takafumi
57Koide, Yuji
58Maemura, Koji
59Yoshihisa, Akiomi
60Kinugasa, Yoshiharu
61Ishida, Katsunori
62Sugihara, Shinobu
63Yanagihara, Kiyotaka
64Takeuchi, Toshiharu
65Okada, Motoi
66Sakai, Tetsuo
67Minoura, Yoshino
68Sato, Takatoshi
69Yokota, Yuya
70Komuro, Issei
71Otsu, Kinya
72Asano, Yoshihiro
73Kajimoto, Katsuya
74Kashiwase, Kazunori
75Ueda, Yasunori
76Komaki, Tomo
77Nakajima, Yoshie
78Ikeda, Yoshifimi
79Tamaki, Toru
80Sakuragawa, Koichiro
81Kohsaka, Shun
82Ando, Shin-ichi
83Kadokami, Toshiaki
84Ishida, Eiko
85Higuchi, Yoshiharu
86Ohte, Nobuyuki
87Shiba, Nobuyuki
88Nochioka, Kotaro
89Shimokawa, Hiroaki
90Koga, Tokushi
91Kida, Keisuke
92Kamisihima, Kazuho
93Nakamura, Makiko
94Touma, Takashi
95Shinjo, Osamu
96Nishimura, Yoshioki
97Uchida, Takahiro
98Amitani, Ken-ichi
99Sato, Naoki
100investigators of the Acute Decompensated Heart Failure Syndromes (ATTEND) registry
collection
0Medline
1MEDLINE
2MEDLINE (Ovid)
3MEDLINE
4MEDLINE
5PubMed
6CrossRef
7Academic OneFile (A&I only)
8ProQuest Central (Corporate)
9Biotechnology Research Abstracts
10Nursing & Allied Health Database
11Physical Education Index
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13ProQuest Central (purchase pre-March 2016)
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36Biotechnology and BioEngineering Abstracts
37Research Library China
38ProQuest One Academic Eastern Edition
39ProQuest One Academic
40ProQuest One Academic UKI Edition
41ProQuest Central China
42ProQuest Central Basic
43MEDLINE - Academic
jtitleThe American journal of cardiology
delivery
delcategoryRemote Search Resource
fulltextno_fulltext
addata
au
0Kajimoto, Katsuya
1Minami, Yuichiro
2Sato, Naoki
3Sato, Naoki
4Munakata, Ryo
5Minami, Yuichiro
6Yumino, Dai
7Mizuno, Masayuki
8Kawada, Erisa
9Ozaki, Yuri
10Nakao, Koichi
11Sawamura, Tadashi
12Ishiki, Ryoji
13Fujinaga, Hiroyuki
14Yamamoto, Takashi
15Hata, Noritake
16Nozaki, Ayaka
17Kawanaka, Hidekazu
18Sato, Yukihito
19Oiwa, Hitoshi
20Matsumoto, Tomoaki
21Yoshida, Daisuke
22Kato, Nobuo
23Shimizu, Nobuyuki
24Chinen, Toshiya
25Kikuchi, Tatsuro
26Nishikido, Toshiyuki
27Yamashita, Tatsuya
28Hirono, Akitoshi
29Mitsudo, Kazuaki
30Kadota, Kazushige
31Makita, Noriko
32Kawabata, Masaaki
33Fujii, Kenichi
34Kobayashi, Shigeki
35Moriuchi, Ikuo
36Murakami, Tatsuaki
37Shimada, Yoshifumi
38Fukuoka, Yoshitomo
39Takata, Yoshifumi
40Miyagi, Manabu
41Tanaka, Nobuhiro
42Yamashina, Akira
43Sudo, Shinji
44Shimamura, Koichi
45Nagashima, Michitaka
46Kaneda, Tomoya
47Ueda, Kosei
48Fujii, Shinya
49Yagi, Masahiro
50Takaki, Jyunko
51Toyama, Takuji
52Oka, Toshiaki
53Naruko, Takahiko
54Abe, Yukio
55Uematsu, Shoko
56Sakamoto, Takafumi
57Koide, Yuji
58Maemura, Koji
59Yoshihisa, Akiomi
60Kinugasa, Yoshiharu
61Ishida, Katsunori
62Sugihara, Shinobu
63Yanagihara, Kiyotaka
64Takeuchi, Toshiharu
65Okada, Motoi
66Sakai, Tetsuo
67Minoura, Yoshino
68Sato, Takatoshi
69Yokota, Yuya
70Komuro, Issei
71Otsu, Kinya
72Asano, Yoshihiro
73Kajimoto, Katsuya
74Kashiwase, Kazunori
75Ueda, Yasunori
76Komaki, Tomo
77Nakajima, Yoshie
78Ikeda, Yoshifimi
79Tamaki, Toru
80Sakuragawa, Koichiro
81Kohsaka, Shun
82Ando, Shin-ichi
83Kadokami, Toshiaki
84Ishida, Eiko
85Higuchi, Yoshiharu
86Ohte, Nobuyuki
87Shiba, Nobuyuki
88Nochioka, Kotaro
89Shimokawa, Hiroaki
90Koga, Tokushi
91Kida, Keisuke
92Kamisihima, Kazuho
93Nakamura, Makiko
94Touma, Takashi
95Shinjo, Osamu
96Nishimura, Yoshioki
97Uchida, Takahiro
98Amitani, Ken-ichi
99Sato, Naoki
aucorpinvestigators of the Acute Decompensated Heart Failure Syndromes (ATTEND) registry
formatjournal
genrearticle
ristypeJOUR
atitleIschemic or Nonischemic Functional Mitral Regurgitation and Outcomes in Patients With Acute Decompensated Heart Failure With Preserved or Reduced Ejection Fraction
jtitleThe American journal of cardiology
addtitleAm J Cardiol
date2017-09-01
risdate2017
volume120
issue5
spage809
epage816
pages809-816
issn0002-9149
eissn1879-1913
abstractThe aim of this study was to evaluate the association of functional mitral regurgitation (FMR), preserved or reduced ejection fraction (EF), and ischemic or nonischemic origin with outcomes in patients discharged alive after hospitalization for acute decompensated heart failure (HF). Of the 4,842 patients enrolled in the Acute Decompensated Heart Failure Syndromes (ATTEND) registry, 3,357 patients were evaluated to assess the association of FMR, preserved or reduced EF, and ischemic or nonischemic origin with the primary end point (all-cause death and readmission for HF after discharge). At the time of discharge, FMR was assessed semiquantitatively (classified as none, mild, or moderate to severe) by color Doppler analysis of the regurgitant jet area. According to multivariable analysis, in the ischemic group, either mild or moderate to severe FMR in patients with a preserved EF had a significantly higher risk of the primary end point than patients without FMR (hazard ratio [HR] 1.60; 95% confidence interval [CI] 1.12 to 2.29; p = 0.010 and HR 1.98; 95% CI 1.30 to 3.01; p = 0.001, respectively). In patients with reduced EF with an ischemic origin, only moderate to severe FMR was associated with a significantly higher risk of the primary end point (HR 1.67; 95% CI 1.11 to 2.50; p = 0.014). In the nonischemic group, there was no significant association between FMR and the primary end point in patients with either a preserved or reduced EF. In conclusion, among patients with acute decompensated HF with a preserved or reduced EF, the association of FMR with adverse outcomes may differ between patients who had an ischemic or nonischemic origin of HF.
copUnited States
pubElsevier Inc
pmid28705383
doi10.1016/j.amjcard.2017.05.051