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Prognosis of Masked and White Coat Uncontrolled Hypertension Detected by Ambulatory Blood Pressure Monitoring in Elderly Treated Hypertensive Patients

Abstract BACKGROUND Prognosis of masked and white coat uncontrolled hypertension (MUCH and WCUCH, respectively) detected by ambulatory blood pressure (BP) monitoring is incompletely clear in elderly treated hypertensive patients. We evaluated prognosis of MUCH and WCUCH identified by ambulatory BP m... Full description

Journal Title: American journal of hypertension 2017, Vol.30 (11), p.1106-1111
Main Author: Pierdomenico, Sante D
Other Authors: Pierdomenico, Anna M , Coccina, Francesca , Porreca, Ettore
Format: Electronic Article Electronic Article
Language: English
Subjects:
Quelle: Alma/SFX Local Collection
Publisher: US: Oxford University Press
ID: ISSN: 0895-7061
Link: https://www.ncbi.nlm.nih.gov/pubmed/29059303
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title: Prognosis of Masked and White Coat Uncontrolled Hypertension Detected by Ambulatory Blood Pressure Monitoring in Elderly Treated Hypertensive Patients
format: Article
creator:
  • Pierdomenico, Sante D
  • Pierdomenico, Anna M
  • Coccina, Francesca
  • Porreca, Ettore
subjects:
  • Age Factors
  • Aged
  • Aged patients
  • Aged, 80 and over
  • Aging
  • Antihypertensive Agents - therapeutic use
  • Blood pressure
  • Blood Pressure - drug effects
  • Blood Pressure Monitoring, Ambulatory
  • Cardiovascular diseases
  • Care and treatment
  • Control
  • Databases, Factual
  • Disease-Free Survival
  • Female
  • Humans
  • Hypertension
  • Male
  • Masked Hypertension - diagnosis
  • Masked Hypertension - drug therapy
  • Masked Hypertension - physiopathology
  • Middle Aged
  • Predictive Value of Tests
  • Prognosis
  • Risk factors
  • Time Factors
  • Treatment Outcome
  • White Coat Hypertension - diagnosis
  • White Coat Hypertension - drug therapy
  • White Coat Hypertension - physiopathology
ispartof: American journal of hypertension, 2017, Vol.30 (11), p.1106-1111
description: Abstract BACKGROUND Prognosis of masked and white coat uncontrolled hypertension (MUCH and WCUCH, respectively) detected by ambulatory blood pressure (BP) monitoring is incompletely clear in elderly treated hypertensive patients. We evaluated prognosis of MUCH and WCUCH identified by ambulatory BP monitoring in this setting. METHODS The occurrence of a composite endpoint was evaluated in 1,191 elderly treated hypertensive patients. Controlled hypertension (CH) was defined as clinic BP
language: eng
source: Alma/SFX Local Collection
identifier: ISSN: 0895-7061
fulltext: fulltext
issn:
  • 0895-7061
  • 1879-1905
url: Link


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titlePrognosis of Masked and White Coat Uncontrolled Hypertension Detected by Ambulatory Blood Pressure Monitoring in Elderly Treated Hypertensive Patients
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creatorPierdomenico, Sante D ; Pierdomenico, Anna M ; Coccina, Francesca ; Porreca, Ettore
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descriptionAbstract BACKGROUND Prognosis of masked and white coat uncontrolled hypertension (MUCH and WCUCH, respectively) detected by ambulatory blood pressure (BP) monitoring is incompletely clear in elderly treated hypertensive patients. We evaluated prognosis of MUCH and WCUCH identified by ambulatory BP monitoring in this setting. METHODS The occurrence of a composite endpoint was evaluated in 1,191 elderly treated hypertensive patients. Controlled hypertension (CH) was defined as clinic BP <140/90 mm Hg and 24-hour BP <130/80 mm Hg, MUCH as clinic BP <140/90 mm Hg and 24-hour BP ≥130 and/or ≥80 mm Hg, WCUCH as clinic BP ≥140 and/or ≥90 mm Hg and 24-hour BP <130/80 mm Hg and sustained uncontrolled hypertension (SUCH) as clinic BP ≥140 and/or ≥90 mm Hg and 24-hour BP ≥130 and/or ≥80 mm Hg. RESULTS MUCH was identified in 142 patients (12% of all the population, 34% of those with normal clinic BP) and WCUCH in 230 patients (19% of all the population, 30% of those with high clinic BP). During the follow-up (9.1 ± 4.9 years, range 0.4–20 years), 392 events occurred. After adjustment for various covariates, patients with MUCH (hazard ratio (HR) 1.60, 95% confidence interval (CI) 1.12–2.29, P = 0.01) and SUCH (HR 1.81, 95% CI, 1.35–2.42, P < 0.001) had significantly higher cardiovascular risk than those with CH, whereas those with WCUCH (HR 1.09, 95% CI, 0.74–1.60, P = 0.66) had not significantly higher risk. CONCLUSIONS In elderly treated hypertensive patients evaluated by ambulatory BP monitoring, compared to individuals with CH, those with MUCH have significantly higher risk and those with WCUCH have slightly and not significantly higher risk.
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subjectAge Factors ; Aged ; Aged patients ; Aged, 80 and over ; Aging ; Antihypertensive Agents - therapeutic use ; Blood pressure ; Blood Pressure - drug effects ; Blood Pressure Monitoring, Ambulatory ; Cardiovascular diseases ; Care and treatment ; Control ; Databases, Factual ; Disease-Free Survival ; Female ; Humans ; Hypertension ; Male ; Masked Hypertension - diagnosis ; Masked Hypertension - drug therapy ; Masked Hypertension - physiopathology ; Middle Aged ; Predictive Value of Tests ; Prognosis ; Risk factors ; Time Factors ; Treatment Outcome ; White Coat Hypertension - diagnosis ; White Coat Hypertension - drug therapy ; White Coat Hypertension - physiopathology
ispartofAmerican journal of hypertension, 2017, Vol.30 (11), p.1106-1111
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0American Journal of Hypertension, Ltd 2017. All rights reserved. For Permissions, please email: journals.permissions@oup.com 2017
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1Pierdomenico, Anna M
2Coccina, Francesca
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0Prognosis of Masked and White Coat Uncontrolled Hypertension Detected by Ambulatory Blood Pressure Monitoring in Elderly Treated Hypertensive Patients
1American journal of hypertension
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descriptionAbstract BACKGROUND Prognosis of masked and white coat uncontrolled hypertension (MUCH and WCUCH, respectively) detected by ambulatory blood pressure (BP) monitoring is incompletely clear in elderly treated hypertensive patients. We evaluated prognosis of MUCH and WCUCH identified by ambulatory BP monitoring in this setting. METHODS The occurrence of a composite endpoint was evaluated in 1,191 elderly treated hypertensive patients. Controlled hypertension (CH) was defined as clinic BP <140/90 mm Hg and 24-hour BP <130/80 mm Hg, MUCH as clinic BP <140/90 mm Hg and 24-hour BP ≥130 and/or ≥80 mm Hg, WCUCH as clinic BP ≥140 and/or ≥90 mm Hg and 24-hour BP <130/80 mm Hg and sustained uncontrolled hypertension (SUCH) as clinic BP ≥140 and/or ≥90 mm Hg and 24-hour BP ≥130 and/or ≥80 mm Hg. RESULTS MUCH was identified in 142 patients (12% of all the population, 34% of those with normal clinic BP) and WCUCH in 230 patients (19% of all the population, 30% of those with high clinic BP). During the follow-up (9.1 ± 4.9 years, range 0.4–20 years), 392 events occurred. After adjustment for various covariates, patients with MUCH (hazard ratio (HR) 1.60, 95% confidence interval (CI) 1.12–2.29, P = 0.01) and SUCH (HR 1.81, 95% CI, 1.35–2.42, P < 0.001) had significantly higher cardiovascular risk than those with CH, whereas those with WCUCH (HR 1.09, 95% CI, 0.74–1.60, P = 0.66) had not significantly higher risk. CONCLUSIONS In elderly treated hypertensive patients evaluated by ambulatory BP monitoring, compared to individuals with CH, those with MUCH have significantly higher risk and those with WCUCH have slightly and not significantly higher risk.
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0Age Factors
1Aged
2Aged patients
3Aged, 80 and over
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5Antihypertensive Agents - therapeutic use
6Blood pressure
7Blood Pressure - drug effects
8Blood Pressure Monitoring, Ambulatory
9Cardiovascular diseases
10Care and treatment
11Control
12Databases, Factual
13Disease-Free Survival
14Female
15Humans
16Hypertension
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18Masked Hypertension - diagnosis
19Masked Hypertension - drug therapy
20Masked Hypertension - physiopathology
21Middle Aged
22Predictive Value of Tests
23Prognosis
24Risk factors
25Time Factors
26Treatment Outcome
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28White Coat Hypertension - drug therapy
29White Coat Hypertension - physiopathology
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abstractAbstract BACKGROUND Prognosis of masked and white coat uncontrolled hypertension (MUCH and WCUCH, respectively) detected by ambulatory blood pressure (BP) monitoring is incompletely clear in elderly treated hypertensive patients. We evaluated prognosis of MUCH and WCUCH identified by ambulatory BP monitoring in this setting. METHODS The occurrence of a composite endpoint was evaluated in 1,191 elderly treated hypertensive patients. Controlled hypertension (CH) was defined as clinic BP <140/90 mm Hg and 24-hour BP <130/80 mm Hg, MUCH as clinic BP <140/90 mm Hg and 24-hour BP ≥130 and/or ≥80 mm Hg, WCUCH as clinic BP ≥140 and/or ≥90 mm Hg and 24-hour BP <130/80 mm Hg and sustained uncontrolled hypertension (SUCH) as clinic BP ≥140 and/or ≥90 mm Hg and 24-hour BP ≥130 and/or ≥80 mm Hg. RESULTS MUCH was identified in 142 patients (12% of all the population, 34% of those with normal clinic BP) and WCUCH in 230 patients (19% of all the population, 30% of those with high clinic BP). During the follow-up (9.1 ± 4.9 years, range 0.4–20 years), 392 events occurred. After adjustment for various covariates, patients with MUCH (hazard ratio (HR) 1.60, 95% confidence interval (CI) 1.12–2.29, P = 0.01) and SUCH (HR 1.81, 95% CI, 1.35–2.42, P < 0.001) had significantly higher cardiovascular risk than those with CH, whereas those with WCUCH (HR 1.09, 95% CI, 0.74–1.60, P = 0.66) had not significantly higher risk. CONCLUSIONS In elderly treated hypertensive patients evaluated by ambulatory BP monitoring, compared to individuals with CH, those with MUCH have significantly higher risk and those with WCUCH have slightly and not significantly higher risk.
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