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Parenteral nutrition in adult inpatients with functioning gastrointestinal tracts: assessment of outcomes

Malnutrition is a common comorbidity that places inpatients at risk of complications, infections, long length of stay, higher costs, and increased mortality. Thus, nutrition support has become an important therapeutic adjunctive to the care of these patients. For patients unable to feed themselves,... Full description

Journal Title: The Lancet (British edition) 2006-04-01, Vol.367 (9516), p.1101-1111
Main Author: Zaloga, Gary P
Format: Electronic Article Electronic Article
Language: English
Subjects:
Quelle: Alma/SFX Local Collection
Publisher: London: Elsevier Ltd
ID: ISSN: 0140-6736
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title: Parenteral nutrition in adult inpatients with functioning gastrointestinal tracts: assessment of outcomes
format: Article
creator:
  • Zaloga, Gary P
subjects:
  • Abridged Index Medicus
  • Adult
  • Allografts
  • Analysis
  • Animals
  • Biological and medical sciences
  • Cancer
  • Carbohydrates
  • Catheters
  • Clinical outcomes
  • Clinical trials
  • Comparative analysis
  • Complications
  • Computational fluid dynamics
  • Digestive system
  • Enteral feeding
  • Enteral Nutrition
  • Fatty acids
  • Feeding
  • Food and nutrition
  • Formulations
  • Gastrointestinal diseases
  • Gastrointestinal system
  • General aspects
  • Health aspects
  • Health risks
  • Hospital Mortality
  • Hospital patients
  • Hospitalization
  • Humans
  • Infections
  • Inflammatory bowel diseases
  • Inpatient care
  • Intestine
  • Intravenous administration
  • Kidney transplantation
  • Length of Stay
  • Lipids
  • Liver
  • Liver diseases
  • Malnutrition
  • Medical colleges
  • Medical research
  • Medical sciences
  • Medicine, Experimental
  • Methods
  • Mortality
  • Nutrients
  • Nutrition
  • Nutritional Requirements
  • Pancreas
  • Pancreatic cancer
  • Parenteral feeding
  • Parenteral nutrition
  • Parenteral Nutrition - adverse effects
  • Parenteral Nutrition - economics
  • Parenteral therapy
  • Patient outcomes
  • Patients
  • Postoperative Period
  • Proteins
  • Randomized Controlled Trials as Topic
  • Renal failure
  • Route selection
  • Surgery
  • Syngeneic grafts
  • Transplantation
  • Trauma
  • Treatment Outcome
  • Tube feeding
ispartof: The Lancet (British edition), 2006-04-01, Vol.367 (9516), p.1101-1111
description: Malnutrition is a common comorbidity that places inpatients at risk of complications, infections, long length of stay, higher costs, and increased mortality. Thus, nutrition support has become an important therapeutic adjunctive to the care of these patients. For patients unable to feed themselves, nutrition can be delivered via the parenteral or enteral routes. The formulations used to deliver nutrients and the route of nutrient delivery, absorption, and processing differ substantially between parenteral and enteral nutrition. Over the past two decades, many randomised clinical trials have assessed the effects of parenteral versus enteral nutrition on outcomes (ie, complications, infections, length of stay, costs, mortality) in diverse inpatient populations. From a search of medical publications, studies were selected that assessed important clinical outcomes of parenteral versus enteral feeding or intravenous fluids in patients with trauma/burn injuries, surgery, cancer, pancreatic disease, inflammatory bowel disease, critical illness, liver failure, acute renal failure, and organ transplantation. Our goal was to determine the optimum route of feeding in these patient groups. The available evidence lends support to the use of enteral over parenteral feeding in inpatients with functioning gastrointestinal tracts.
language: eng
source: Alma/SFX Local Collection
identifier: ISSN: 0140-6736
fulltext: fulltext
issn:
  • 0140-6736
  • 1474-547X
url: Link


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descriptionMalnutrition is a common comorbidity that places inpatients at risk of complications, infections, long length of stay, higher costs, and increased mortality. Thus, nutrition support has become an important therapeutic adjunctive to the care of these patients. For patients unable to feed themselves, nutrition can be delivered via the parenteral or enteral routes. The formulations used to deliver nutrients and the route of nutrient delivery, absorption, and processing differ substantially between parenteral and enteral nutrition. Over the past two decades, many randomised clinical trials have assessed the effects of parenteral versus enteral nutrition on outcomes (ie, complications, infections, length of stay, costs, mortality) in diverse inpatient populations. From a search of medical publications, studies were selected that assessed important clinical outcomes of parenteral versus enteral feeding or intravenous fluids in patients with trauma/burn injuries, surgery, cancer, pancreatic disease, inflammatory bowel disease, critical illness, liver failure, acute renal failure, and organ transplantation. Our goal was to determine the optimum route of feeding in these patient groups. The available evidence lends support to the use of enteral over parenteral feeding in inpatients with functioning gastrointestinal tracts.
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1EISSN: 1474-547X
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3PMID: 16581410
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publisherLondon: Elsevier Ltd
subjectAbridged Index Medicus ; Adult ; Allografts ; Analysis ; Animals ; Biological and medical sciences ; Cancer ; Carbohydrates ; Catheters ; Clinical outcomes ; Clinical trials ; Comparative analysis ; Complications ; Computational fluid dynamics ; Digestive system ; Enteral feeding ; Enteral Nutrition ; Fatty acids ; Feeding ; Food and nutrition ; Formulations ; Gastrointestinal diseases ; Gastrointestinal system ; General aspects ; Health aspects ; Health risks ; Hospital Mortality ; Hospital patients ; Hospitalization ; Humans ; Infections ; Inflammatory bowel diseases ; Inpatient care ; Intestine ; Intravenous administration ; Kidney transplantation ; Length of Stay ; Lipids ; Liver ; Liver diseases ; Malnutrition ; Medical colleges ; Medical research ; Medical sciences ; Medicine, Experimental ; Methods ; Mortality ; Nutrients ; Nutrition ; Nutritional Requirements ; Pancreas ; Pancreatic cancer ; Parenteral feeding ; Parenteral nutrition ; Parenteral Nutrition - adverse effects ; Parenteral Nutrition - economics ; Parenteral therapy ; Patient outcomes ; Patients ; Postoperative Period ; Proteins ; Randomized Controlled Trials as Topic ; Renal failure ; Route selection ; Surgery ; Syngeneic grafts ; Transplantation ; Trauma ; Treatment Outcome ; Tube feeding
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descriptionMalnutrition is a common comorbidity that places inpatients at risk of complications, infections, long length of stay, higher costs, and increased mortality. Thus, nutrition support has become an important therapeutic adjunctive to the care of these patients. For patients unable to feed themselves, nutrition can be delivered via the parenteral or enteral routes. The formulations used to deliver nutrients and the route of nutrient delivery, absorption, and processing differ substantially between parenteral and enteral nutrition. Over the past two decades, many randomised clinical trials have assessed the effects of parenteral versus enteral nutrition on outcomes (ie, complications, infections, length of stay, costs, mortality) in diverse inpatient populations. From a search of medical publications, studies were selected that assessed important clinical outcomes of parenteral versus enteral feeding or intravenous fluids in patients with trauma/burn injuries, surgery, cancer, pancreatic disease, inflammatory bowel disease, critical illness, liver failure, acute renal failure, and organ transplantation. Our goal was to determine the optimum route of feeding in these patient groups. The available evidence lends support to the use of enteral over parenteral feeding in inpatients with functioning gastrointestinal tracts.
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16Enteral Nutrition
17Fatty acids
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19Food and nutrition
20Formulations
21Gastrointestinal diseases
22Gastrointestinal system
23General aspects
24Health aspects
25Health risks
26Hospital Mortality
27Hospital patients
28Hospitalization
29Humans
30Infections
31Inflammatory bowel diseases
32Inpatient care
33Intestine
34Intravenous administration
35Kidney transplantation
36Length of Stay
37Lipids
38Liver
39Liver diseases
40Malnutrition
41Medical colleges
42Medical research
43Medical sciences
44Medicine, Experimental
45Methods
46Mortality
47Nutrients
48Nutrition
49Nutritional Requirements
50Pancreas
51Pancreatic cancer
52Parenteral feeding
53Parenteral nutrition
54Parenteral Nutrition - adverse effects
55Parenteral Nutrition - economics
56Parenteral therapy
57Patient outcomes
58Patients
59Postoperative Period
60Proteins
61Randomized Controlled Trials as Topic
62Renal failure
63Route selection
64Surgery
65Syngeneic grafts
66Transplantation
67Trauma
68Treatment Outcome
69Tube feeding
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abstractMalnutrition is a common comorbidity that places inpatients at risk of complications, infections, long length of stay, higher costs, and increased mortality. Thus, nutrition support has become an important therapeutic adjunctive to the care of these patients. For patients unable to feed themselves, nutrition can be delivered via the parenteral or enteral routes. The formulations used to deliver nutrients and the route of nutrient delivery, absorption, and processing differ substantially between parenteral and enteral nutrition. Over the past two decades, many randomised clinical trials have assessed the effects of parenteral versus enteral nutrition on outcomes (ie, complications, infections, length of stay, costs, mortality) in diverse inpatient populations. From a search of medical publications, studies were selected that assessed important clinical outcomes of parenteral versus enteral feeding or intravenous fluids in patients with trauma/burn injuries, surgery, cancer, pancreatic disease, inflammatory bowel disease, critical illness, liver failure, acute renal failure, and organ transplantation. Our goal was to determine the optimum route of feeding in these patient groups. The available evidence lends support to the use of enteral over parenteral feeding in inpatients with functioning gastrointestinal tracts.
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pubElsevier Ltd
pmid16581410
doi10.1016/S0140-6736(06)68307-4