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Physical Activity and Cause-Specific Mortality in Men: Further Evidence from the Whitehall Study

Reports of studies relating physical activity to stroke and cancer sub-types indicate inconsistent findings. Some are hampered by low statistical power, owing to a low number of events, and a failure to adjust for potential confounding variables. The purpose of this study was to relate physical acti... Full description

Journal Title: European journal of epidemiology 2001-01-01, Vol.17 (9), p.863-869
Main Author: BATTY, G. David
Other Authors: SHIPLEY, Martin J , MARMOT, Michael , SMITH, George Davey
Format: Electronic Article Electronic Article
Language: English
Subjects:
Publisher: Dordrecht: Kluwer Academic Publishers
ID: ISSN: 0393-2990
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title: Physical Activity and Cause-Specific Mortality in Men: Further Evidence from the Whitehall Study
format: Article
creator:
  • BATTY, G. David
  • SHIPLEY, Martin J
  • MARMOT, Michael
  • SMITH, George Davey
subjects:
  • Adult
  • Biological and medical sciences
  • Cancer
  • Cardiology. Vascular system
  • Cause of Death
  • Cigarette smoking
  • Coronary artery disease
  • Coronary Disease - mortality
  • Coronary heart disease
  • Diabetes
  • England - epidemiology
  • Epidemiology
  • Exercise
  • Heart
  • Humans
  • Lung neoplasms
  • Male
  • Medical sciences
  • Middle Aged
  • Mortality
  • Mortality - trends
  • Proportional Hazards Models
  • Prospective Studies
  • Regression Analysis
  • Respiratory Tract Diseases - mortality
  • Risk Factors
  • Stroke - mortality
  • Strokes
  • Travel
ispartof: European journal of epidemiology, 2001-01-01, Vol.17 (9), p.863-869
description: Reports of studies relating physical activity to stroke and cancer sub-types indicate inconsistent findings. Some are hampered by low statistical power, owing to a low number of events, and a failure to adjust for potential confounding variables. The purpose of this study was to relate physical activity to 12 mortality endpoints in a prospective cohort study of 11,663 men aged 40-64 years who responded to an enquiry about travel activity during a baseline medical examination conducted between 1967 and 1969. During 25 years of follow-up there were 4672 deaths. Travel activity was inversely related to mortality attributable to all-causes, coronary heart disease, respiratory disease and lung cancer, whereas the association with stroke was positive. There was evidence for attenuation of some of these associations on adjustment for potentially confounding variables. Our simplistic measure of physical activity may, in part, explain the weak associations seen.
language: eng
source:
identifier: ISSN: 0393-2990
fulltext: no_fulltext
issn:
  • 0393-2990
  • 1573-7284
url: Link


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descriptionReports of studies relating physical activity to stroke and cancer sub-types indicate inconsistent findings. Some are hampered by low statistical power, owing to a low number of events, and a failure to adjust for potential confounding variables. The purpose of this study was to relate physical activity to 12 mortality endpoints in a prospective cohort study of 11,663 men aged 40-64 years who responded to an enquiry about travel activity during a baseline medical examination conducted between 1967 and 1969. During 25 years of follow-up there were 4672 deaths. Travel activity was inversely related to mortality attributable to all-causes, coronary heart disease, respiratory disease and lung cancer, whereas the association with stroke was positive. There was evidence for attenuation of some of these associations on adjustment for potentially confounding variables. Our simplistic measure of physical activity may, in part, explain the weak associations seen.
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subjectAdult ; Biological and medical sciences ; Cancer ; Cardiology. Vascular system ; Cause of Death ; Cigarette smoking ; Coronary artery disease ; Coronary Disease - mortality ; Coronary heart disease ; Diabetes ; England - epidemiology ; Epidemiology ; Exercise ; Heart ; Humans ; Lung neoplasms ; Male ; Medical sciences ; Middle Aged ; Mortality ; Mortality - trends ; Proportional Hazards Models ; Prospective Studies ; Regression Analysis ; Respiratory Tract Diseases - mortality ; Risk Factors ; Stroke - mortality ; Strokes ; Travel
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abstractReports of studies relating physical activity to stroke and cancer sub-types indicate inconsistent findings. Some are hampered by low statistical power, owing to a low number of events, and a failure to adjust for potential confounding variables. The purpose of this study was to relate physical activity to 12 mortality endpoints in a prospective cohort study of 11,663 men aged 40-64 years who responded to an enquiry about travel activity during a baseline medical examination conducted between 1967 and 1969. During 25 years of follow-up there were 4672 deaths. Travel activity was inversely related to mortality attributable to all-causes, coronary heart disease, respiratory disease and lung cancer, whereas the association with stroke was positive. There was evidence for attenuation of some of these associations on adjustment for potentially confounding variables. Our simplistic measure of physical activity may, in part, explain the weak associations seen.
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doi10.1023/A:1015609909969