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A follow-up study found that cardiovascular risk in middle age predicted mortality and quality of life in old age

Cardiovascular risk reduction, while saving lives, may prolong the time with disability and impair the quality of life in survivors. We compared the consequences of middle age cardiovascular risk in old age. In 1974, risk was low in 593 (low-risk group) and high in 610 men (high-risk group). At base... Full description

Journal Title: Journal of clinical epidemiology 2004, Vol.57 (4), p.415-421
Main Author: Strandberg, Arto
Other Authors: Strandberg, Timo E , Salomaa, Veikko V , Pitkälä, Kaisu , Häppölä, Olli , Miettinen, Tatu A
Format: Electronic Article Electronic Article
Language: English
Subjects:
Quelle: Alma/SFX Local Collection
Publisher: New York, NY: Elsevier Inc
ID: ISSN: 0895-4356
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recordid: cdi_proquest_miscellaneous_71916575
title: A follow-up study found that cardiovascular risk in middle age predicted mortality and quality of life in old age
format: Article
creator:
  • Strandberg, Arto
  • Strandberg, Timo E
  • Salomaa, Veikko V
  • Pitkälä, Kaisu
  • Häppölä, Olli
  • Miettinen, Tatu A
subjects:
  • Aged
  • Analysis. Health state
  • Atherosclerosis (general aspects, experimental research)
  • Biological and medical sciences
  • Blood and lymphatic vessels
  • Cardiology. Vascular system
  • Cardiovascular Diseases - etiology
  • Cardiovascular Diseases - mortality
  • Cardiovascular Diseases - prevention & control
  • Compression of morbidity
  • Epidemiologic Methods
  • Epidemiology
  • Finland - epidemiology
  • General aspects
  • Health Status Indicators
  • Humans
  • Life Style
  • Male
  • Medical sciences
  • Middle Aged
  • Mortality
  • Public health. Hygiene
  • Public health. Hygiene-occupational medicine
  • Quality of Life
  • Risk factors
ispartof: Journal of clinical epidemiology, 2004, Vol.57 (4), p.415-421
description: Cardiovascular risk reduction, while saving lives, may prolong the time with disability and impair the quality of life in survivors. We compared the consequences of middle age cardiovascular risk in old age. In 1974, risk was low in 593 (low-risk group) and high in 610 men (high-risk group). At baseline, all were healthy with similar age and socioeconomic status. Lifestyle and clinical factors, including quality of life (RAND-36), were surveyed with a questionnaire in 2000, and mortality was determined up to 2002. During the follow-up, 303 men died, with mortality 54% higher in the high-risk group ( P = .001). In the 2000 survey, high-risk men still had significantly greater BMI, higher blood glucose, higher prevalence of smoking, and more sedentary lifestyle, and they reported more both cardiovascular and noncardiovascular diseases. All the RAND-36 scales were worse in the high-risk group; of the two component summary scores, physical (PCS), but not mental (MCS) score, was significantly lower in the high-risk group. Low cardiovascular risk in middle age was associated with lower mortality, morbidity, and better quality of life in old age 26 years later. The results may support the theory of compression of morbidity.
language: eng
source: Alma/SFX Local Collection
identifier: ISSN: 0895-4356
fulltext: fulltext
issn:
  • 0895-4356
  • 1878-5921
url: Link


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descriptionCardiovascular risk reduction, while saving lives, may prolong the time with disability and impair the quality of life in survivors. We compared the consequences of middle age cardiovascular risk in old age. In 1974, risk was low in 593 (low-risk group) and high in 610 men (high-risk group). At baseline, all were healthy with similar age and socioeconomic status. Lifestyle and clinical factors, including quality of life (RAND-36), were surveyed with a questionnaire in 2000, and mortality was determined up to 2002. During the follow-up, 303 men died, with mortality 54% higher in the high-risk group ( P = .001). In the 2000 survey, high-risk men still had significantly greater BMI, higher blood glucose, higher prevalence of smoking, and more sedentary lifestyle, and they reported more both cardiovascular and noncardiovascular diseases. All the RAND-36 scales were worse in the high-risk group; of the two component summary scores, physical (PCS), but not mental (MCS) score, was significantly lower in the high-risk group. Low cardiovascular risk in middle age was associated with lower mortality, morbidity, and better quality of life in old age 26 years later. The results may support the theory of compression of morbidity.
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subjectAged ; Analysis. Health state ; Atherosclerosis (general aspects, experimental research) ; Biological and medical sciences ; Blood and lymphatic vessels ; Cardiology. Vascular system ; Cardiovascular Diseases - etiology ; Cardiovascular Diseases - mortality ; Cardiovascular Diseases - prevention & control ; Compression of morbidity ; Epidemiologic Methods ; Epidemiology ; Finland - epidemiology ; General aspects ; Health Status Indicators ; Humans ; Life Style ; Male ; Medical sciences ; Middle Aged ; Mortality ; Public health. Hygiene ; Public health. Hygiene-occupational medicine ; Quality of Life ; Risk factors
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descriptionCardiovascular risk reduction, while saving lives, may prolong the time with disability and impair the quality of life in survivors. We compared the consequences of middle age cardiovascular risk in old age. In 1974, risk was low in 593 (low-risk group) and high in 610 men (high-risk group). At baseline, all were healthy with similar age and socioeconomic status. Lifestyle and clinical factors, including quality of life (RAND-36), were surveyed with a questionnaire in 2000, and mortality was determined up to 2002. During the follow-up, 303 men died, with mortality 54% higher in the high-risk group ( P = .001). In the 2000 survey, high-risk men still had significantly greater BMI, higher blood glucose, higher prevalence of smoking, and more sedentary lifestyle, and they reported more both cardiovascular and noncardiovascular diseases. All the RAND-36 scales were worse in the high-risk group; of the two component summary scores, physical (PCS), but not mental (MCS) score, was significantly lower in the high-risk group. Low cardiovascular risk in middle age was associated with lower mortality, morbidity, and better quality of life in old age 26 years later. The results may support the theory of compression of morbidity.
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abstractCardiovascular risk reduction, while saving lives, may prolong the time with disability and impair the quality of life in survivors. We compared the consequences of middle age cardiovascular risk in old age. In 1974, risk was low in 593 (low-risk group) and high in 610 men (high-risk group). At baseline, all were healthy with similar age and socioeconomic status. Lifestyle and clinical factors, including quality of life (RAND-36), were surveyed with a questionnaire in 2000, and mortality was determined up to 2002. During the follow-up, 303 men died, with mortality 54% higher in the high-risk group ( P = .001). In the 2000 survey, high-risk men still had significantly greater BMI, higher blood glucose, higher prevalence of smoking, and more sedentary lifestyle, and they reported more both cardiovascular and noncardiovascular diseases. All the RAND-36 scales were worse in the high-risk group; of the two component summary scores, physical (PCS), but not mental (MCS) score, was significantly lower in the high-risk group. Low cardiovascular risk in middle age was associated with lower mortality, morbidity, and better quality of life in old age 26 years later. The results may support the theory of compression of morbidity.
copNew York, NY
pubElsevier Inc
pmid15135845
doi10.1016/j.jclinepi.2003.09.013