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Blood Pressure Indices and Cardiovascular Disease in the Asia Pacific Region: A Pooled Analysis

ABSTRACT—This article aims to compare the importance of systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure (MAP), and pulse pressure (PP) as risk factors for stroke and ischemic heart disease and to assess whether the patterns are consistent by age and gender. Cox... Full description

Journal Title: Hypertension 2003-07-01, Vol.42 (1), p.69-75
Main Author: Lawes, Carlene M M
Other Authors: Bennett, Derrick A , Parag, Varsha , Woodward, Mark , Whitlock, Gary , Lam, Tai Hing , Suh, Il , Rodgers, Anthony
Format: Electronic Article Electronic Article
Language: English
Subjects:
Publisher: Philadelphia, PA: Am Heart Assoc
ID: ISSN: 0194-911X
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recordid: cdi_proquest_miscellaneous_73433005
title: Blood Pressure Indices and Cardiovascular Disease in the Asia Pacific Region: A Pooled Analysis
format: Article
creator:
  • Lawes, Carlene M M
  • Bennett, Derrick A
  • Parag, Varsha
  • Woodward, Mark
  • Whitlock, Gary
  • Lam, Tai Hing
  • Suh, Il
  • Rodgers, Anthony
subjects:
  • Adult
  • Age Factors
  • Aged
  • Australia - epidemiology
  • Biological and medical sciences
  • Blood Pressure
  • Cardiology. Vascular system
  • Coronary heart disease
  • Far East - epidemiology
  • Female
  • Follow-Up Studies
  • Heart
  • Humans
  • Male
  • Medical sciences
  • Middle Aged
  • Myocardial Ischemia - epidemiology
  • Myocardial Ischemia - mortality
  • New Zealand - epidemiology
  • Risk Factors
  • Sex Factors
  • Stroke - epidemiology
  • Stroke - mortality
ispartof: Hypertension, 2003-07-01, Vol.42 (1), p.69-75
description: ABSTRACT—This article aims to compare the importance of systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure (MAP), and pulse pressure (PP) as risk factors for stroke and ischemic heart disease and to assess whether the patterns are consistent by age and gender. Cox proportional-hazards regression, adjusted for cholesterol and smoking, was used to assess the associations of the 4 BP indices with stroke and ischemic heart disease by age and gender. The relative importance of individual indices was assessed with a hazard ratios for a 1-SD change in BP and by likelihood-ratio χ tests. The influence of >1 BP index in the Cox model was also estimated. The analyses demonstrated similar associations of SBP, DBP, and MAP with both fatal stroke and ischemic heart diseases, which were stronger than those of PP. Both SBP and MAP tended to be more important in the regression model than DBP or PP. In Cox models including DBP, addition of SBP improved the goodness of fit at all ages and for both genders. However, in Cox models including SBP, addition of DBP typically resulted in little incremental benefit over and above that of SBP alone. These data suggest that if time or resources are highly constrained, such as in much-needed epidemiologic surveys in developing countries, very little is lost from only measuring SBP.
language: eng
source:
identifier: ISSN: 0194-911X
fulltext: no_fulltext
issn:
  • 0194-911X
  • 1524-4563
url: Link


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titleBlood Pressure Indices and Cardiovascular Disease in the Asia Pacific Region: A Pooled Analysis
creatorLawes, Carlene M M ; Bennett, Derrick A ; Parag, Varsha ; Woodward, Mark ; Whitlock, Gary ; Lam, Tai Hing ; Suh, Il ; Rodgers, Anthony
creatorcontribLawes, Carlene M M ; Bennett, Derrick A ; Parag, Varsha ; Woodward, Mark ; Whitlock, Gary ; Lam, Tai Hing ; Suh, Il ; Rodgers, Anthony ; Asia Pacific Cohort Studies Collaboration
descriptionABSTRACT—This article aims to compare the importance of systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure (MAP), and pulse pressure (PP) as risk factors for stroke and ischemic heart disease and to assess whether the patterns are consistent by age and gender. Cox proportional-hazards regression, adjusted for cholesterol and smoking, was used to assess the associations of the 4 BP indices with stroke and ischemic heart disease by age and gender. The relative importance of individual indices was assessed with a hazard ratios for a 1-SD change in BP and by likelihood-ratio χ tests. The influence of >1 BP index in the Cox model was also estimated. The analyses demonstrated similar associations of SBP, DBP, and MAP with both fatal stroke and ischemic heart diseases, which were stronger than those of PP. Both SBP and MAP tended to be more important in the regression model than DBP or PP. In Cox models including DBP, addition of SBP improved the goodness of fit at all ages and for both genders. However, in Cox models including SBP, addition of DBP typically resulted in little incremental benefit over and above that of SBP alone. These data suggest that if time or resources are highly constrained, such as in much-needed epidemiologic surveys in developing countries, very little is lost from only measuring SBP.
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subjectAdult ; Age Factors ; Aged ; Australia - epidemiology ; Biological and medical sciences ; Blood Pressure ; Cardiology. Vascular system ; Coronary heart disease ; Far East - epidemiology ; Female ; Follow-Up Studies ; Heart ; Humans ; Male ; Medical sciences ; Middle Aged ; Myocardial Ischemia - epidemiology ; Myocardial Ischemia - mortality ; New Zealand - epidemiology ; Risk Factors ; Sex Factors ; Stroke - epidemiology ; Stroke - mortality
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descriptionABSTRACT—This article aims to compare the importance of systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure (MAP), and pulse pressure (PP) as risk factors for stroke and ischemic heart disease and to assess whether the patterns are consistent by age and gender. Cox proportional-hazards regression, adjusted for cholesterol and smoking, was used to assess the associations of the 4 BP indices with stroke and ischemic heart disease by age and gender. The relative importance of individual indices was assessed with a hazard ratios for a 1-SD change in BP and by likelihood-ratio χ tests. The influence of >1 BP index in the Cox model was also estimated. The analyses demonstrated similar associations of SBP, DBP, and MAP with both fatal stroke and ischemic heart diseases, which were stronger than those of PP. Both SBP and MAP tended to be more important in the regression model than DBP or PP. In Cox models including DBP, addition of SBP improved the goodness of fit at all ages and for both genders. However, in Cox models including SBP, addition of DBP typically resulted in little incremental benefit over and above that of SBP alone. These data suggest that if time or resources are highly constrained, such as in much-needed epidemiologic surveys in developing countries, very little is lost from only measuring SBP.
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abstractABSTRACT—This article aims to compare the importance of systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure (MAP), and pulse pressure (PP) as risk factors for stroke and ischemic heart disease and to assess whether the patterns are consistent by age and gender. Cox proportional-hazards regression, adjusted for cholesterol and smoking, was used to assess the associations of the 4 BP indices with stroke and ischemic heart disease by age and gender. The relative importance of individual indices was assessed with a hazard ratios for a 1-SD change in BP and by likelihood-ratio χ tests. The influence of >1 BP index in the Cox model was also estimated. The analyses demonstrated similar associations of SBP, DBP, and MAP with both fatal stroke and ischemic heart diseases, which were stronger than those of PP. Both SBP and MAP tended to be more important in the regression model than DBP or PP. In Cox models including DBP, addition of SBP improved the goodness of fit at all ages and for both genders. However, in Cox models including SBP, addition of DBP typically resulted in little incremental benefit over and above that of SBP alone. These data suggest that if time or resources are highly constrained, such as in much-needed epidemiologic surveys in developing countries, very little is lost from only measuring SBP.
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