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Treatment and care for injecting drug users with HIV infection: a review of barriers and ways forward

Summary We review evidence for effectiveness, cost-effectiveness, and coverage of antiretroviral therapy (ART) for injecting drug users (IDUs) infected with HIV, with particular attention to low-income and middle-income countries. In these countries, nearly half (47%) of all IDUs infected with HIV a... Full description

Journal Title: The Lancet (British edition) 2010, Vol.376 (9738), p.355-366
Main Author: Wolfe, Daniel, MPH
Other Authors: Carrieri, M Patrizia, PhD , Shepard, Donald, PhD
Format: Electronic Article Electronic Article
Language: English
Subjects:
Quelle: Alma/SFX Local Collection
Publisher: Kidlington: Elsevier Ltd
ID: ISSN: 0140-6736
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title: Treatment and care for injecting drug users with HIV infection: a review of barriers and ways forward
format: Article
creator:
  • Wolfe, Daniel, MPH
  • Carrieri, M Patrizia, PhD
  • Shepard, Donald, PhD
subjects:
  • Abridged Index Medicus
  • Addictive behaviors
  • Adult and adolescent clinical studies
  • Anti-HIV Agents - economics
  • Anti-HIV Agents - therapeutic use
  • Anti-Retroviral Agents - therapeutic use
  • Biological and medical sciences
  • Buprenorphine - therapeutic use
  • Care and treatment
  • China
  • Complications and side effects
  • Cost-Benefit Analysis
  • Developing Countries - economics
  • Drug abuse
  • Drug addiction
  • Drug addicts
  • Drug Costs
  • Drug therapy
  • General aspects
  • Health aspects
  • Health Services Accessibility
  • Highly active antiretroviral therapy
  • HIV infection
  • HIV Infections - drug therapy
  • HIV Infections - economics
  • HIV Infections - epidemiology
  • HIV Infections - etiology
  • Human immunodeficiency virus
  • Human viral diseases
  • Humans
  • Income
  • Infectious diseases
  • Internal Medicine
  • Intravenous drug abuse
  • Malaysia
  • Medical sciences
  • Methadone - therapeutic use
  • Narcotic Antagonists - economics
  • Narcotic Antagonists - therapeutic use
  • Narcotics - economics
  • Narcotics - therapeutic use
  • Narration
  • Prisoners
  • Prisons
  • Psychology. Psychoanalysis. Psychiatry
  • Psychopathology. Psychiatry
  • Research
  • Risk factors
  • Russia
  • Substance Abuse, Intravenous - complications
  • Substance Abuse, Intravenous - drug therapy
  • Substance Abuse, Intravenous - economics
  • Substance Abuse, Intravenous - epidemiology
  • Ukraine
  • Vietnam
  • Viral diseases
  • Viral diseases of the lymphoid tissue and the blood. Aids
ispartof: The Lancet (British edition), 2010, Vol.376 (9738), p.355-366
description: Summary We review evidence for effectiveness, cost-effectiveness, and coverage of antiretroviral therapy (ART) for injecting drug users (IDUs) infected with HIV, with particular attention to low-income and middle-income countries. In these countries, nearly half (47%) of all IDUs infected with HIV are in five nations—China, Vietnam, Russia, Ukraine, and Malaysia. In all five countries, IDU access to ART is disproportionately low, and systemic and structural obstacles restrict treatment access. IDUs are 67% of cumulative HIV cases in these countries, but only 25% of those receiving ART. Integration of ART with opioid substitution and tuberculosis treatment, increased peer engagement in treatment delivery, and reform of harmful policies—including police use of drug-user registries, detention of drug users in centres offering no evidence-based treatment, and imprisonment for possession of drugs for personal use—are needed to improve ART coverage of IDUs.
language: eng
source: Alma/SFX Local Collection
identifier: ISSN: 0140-6736
fulltext: fulltext
issn:
  • 0140-6736
  • 1474-547X
url: Link


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descriptionSummary We review evidence for effectiveness, cost-effectiveness, and coverage of antiretroviral therapy (ART) for injecting drug users (IDUs) infected with HIV, with particular attention to low-income and middle-income countries. In these countries, nearly half (47%) of all IDUs infected with HIV are in five nations—China, Vietnam, Russia, Ukraine, and Malaysia. In all five countries, IDU access to ART is disproportionately low, and systemic and structural obstacles restrict treatment access. IDUs are 67% of cumulative HIV cases in these countries, but only 25% of those receiving ART. Integration of ART with opioid substitution and tuberculosis treatment, increased peer engagement in treatment delivery, and reform of harmful policies—including police use of drug-user registries, detention of drug users in centres offering no evidence-based treatment, and imprisonment for possession of drugs for personal use—are needed to improve ART coverage of IDUs.
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subjectAbridged Index Medicus ; Addictive behaviors ; Adult and adolescent clinical studies ; Anti-HIV Agents - economics ; Anti-HIV Agents - therapeutic use ; Anti-Retroviral Agents - therapeutic use ; Biological and medical sciences ; Buprenorphine - therapeutic use ; Care and treatment ; China ; Complications and side effects ; Cost-Benefit Analysis ; Developing Countries - economics ; Drug abuse ; Drug addiction ; Drug addicts ; Drug Costs ; Drug therapy ; General aspects ; Health aspects ; Health Services Accessibility ; Highly active antiretroviral therapy ; HIV infection ; HIV Infections - drug therapy ; HIV Infections - economics ; HIV Infections - epidemiology ; HIV Infections - etiology ; Human immunodeficiency virus ; Human viral diseases ; Humans ; Income ; Infectious diseases ; Internal Medicine ; Intravenous drug abuse ; Malaysia ; Medical sciences ; Methadone - therapeutic use ; Narcotic Antagonists - economics ; Narcotic Antagonists - therapeutic use ; Narcotics - economics ; Narcotics - therapeutic use ; Narration ; Prisoners ; Prisons ; Psychology. Psychoanalysis. Psychiatry ; Psychopathology. Psychiatry ; Research ; Risk factors ; Russia ; Substance Abuse, Intravenous - complications ; Substance Abuse, Intravenous - drug therapy ; Substance Abuse, Intravenous - economics ; Substance Abuse, Intravenous - epidemiology ; Ukraine ; Vietnam ; Viral diseases ; Viral diseases of the lymphoid tissue and the blood. Aids
ispartofThe Lancet (British edition), 2010, Vol.376 (9738), p.355-366
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descriptionSummary We review evidence for effectiveness, cost-effectiveness, and coverage of antiretroviral therapy (ART) for injecting drug users (IDUs) infected with HIV, with particular attention to low-income and middle-income countries. In these countries, nearly half (47%) of all IDUs infected with HIV are in five nations—China, Vietnam, Russia, Ukraine, and Malaysia. In all five countries, IDU access to ART is disproportionately low, and systemic and structural obstacles restrict treatment access. IDUs are 67% of cumulative HIV cases in these countries, but only 25% of those receiving ART. Integration of ART with opioid substitution and tuberculosis treatment, increased peer engagement in treatment delivery, and reform of harmful policies—including police use of drug-user registries, detention of drug users in centres offering no evidence-based treatment, and imprisonment for possession of drugs for personal use—are needed to improve ART coverage of IDUs.
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1Addictive behaviors
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23HIV Infections - drug therapy
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30Income
31Infectious diseases
32Internal Medicine
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35Medical sciences
36Methadone - therapeutic use
37Narcotic Antagonists - economics
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44Psychology. Psychoanalysis. Psychiatry
45Psychopathology. Psychiatry
46Research
47Risk factors
48Russia
49Substance Abuse, Intravenous - complications
50Substance Abuse, Intravenous - drug therapy
51Substance Abuse, Intravenous - economics
52Substance Abuse, Intravenous - epidemiology
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54Vietnam
55Viral diseases
56Viral diseases of the lymphoid tissue and the blood. Aids
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authorWolfe, Daniel, MPH ; Carrieri, M Patrizia, PhD ; Shepard, Donald, PhD
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14Drug addiction
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16Drug Costs
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18General aspects
19Health aspects
20Health Services Accessibility
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54Vietnam
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abstractSummary We review evidence for effectiveness, cost-effectiveness, and coverage of antiretroviral therapy (ART) for injecting drug users (IDUs) infected with HIV, with particular attention to low-income and middle-income countries. In these countries, nearly half (47%) of all IDUs infected with HIV are in five nations—China, Vietnam, Russia, Ukraine, and Malaysia. In all five countries, IDU access to ART is disproportionately low, and systemic and structural obstacles restrict treatment access. IDUs are 67% of cumulative HIV cases in these countries, but only 25% of those receiving ART. Integration of ART with opioid substitution and tuberculosis treatment, increased peer engagement in treatment delivery, and reform of harmful policies—including police use of drug-user registries, detention of drug users in centres offering no evidence-based treatment, and imprisonment for possession of drugs for personal use—are needed to improve ART coverage of IDUs.
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