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Breast cancer and hormone-replacement therapy in the Million Women Study

Current use of hormone-replacement therapy (HRT) increases the incidence of breast cancer. The Million Women Study was set up to investigate the effects of specific types of HRT on incident and fatal breast cancer. 1084110 UK women aged 50–64 years were recruited into the Million Women Study between... Full description

Journal Title: The Lancet (British edition) 2003, Vol.362 (9382), p.419-427
Main Author: Beral, Valerie
Format: Electronic Article Electronic Article
Language: English
Subjects:
Age
Quelle: Alma/SFX Local Collection
Publisher: England: Elsevier Ltd
ID: ISSN: 0140-6736
Link: https://www.ncbi.nlm.nih.gov/pubmed/12927427
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title: Breast cancer and hormone-replacement therapy in the Million Women Study
format: Article
creator:
  • Beral, Valerie
subjects:
  • Adverse and side effects
  • Age
  • Breast cancer
  • Breast Neoplasms - chemically induced
  • Breast Neoplasms - epidemiology
  • Breast Neoplasms - mortality
  • Cancer
  • England - epidemiology
  • Epidemiology
  • Estrogen
  • Estrogen Replacement Therapy - adverse effects
  • Estrogens
  • Fatalities
  • Female
  • Follow-Up Studies
  • Formulations
  • Health risk assessment
  • Health risks
  • Hormone replacement therapy
  • Hormone therapy
  • Humans
  • Incidence
  • Invasiveness
  • Mammography
  • Mass Screening - statistics & numerical data
  • Medical research
  • Menopause
  • Menstruation
  • Middle Aged
  • Mortality
  • National Health Programs - statistics & numerical data
  • Oncology, Experimental
  • Registries - statistics & numerical data
  • Risk
  • Risk assessment
  • Risk factors
  • Skin cancer
  • Statistics
  • Therapy
  • Tibolone
  • United Kingdom
  • Usage
  • Women
  • Womens health
ispartof: The Lancet (British edition), 2003, Vol.362 (9382), p.419-427
description: Current use of hormone-replacement therapy (HRT) increases the incidence of breast cancer. The Million Women Study was set up to investigate the effects of specific types of HRT on incident and fatal breast cancer. 1084110 UK women aged 50–64 years were recruited into the Million Women Study between 1996 and 2001, provided information about their use of HRT and other personal details, and were followed up for cancer incidence and death. Half the women had used HRT; 9364 incident invasive breast cancers and 637 breast cancer deaths were registered after an average of 2·6 and 4·1 years of follow-up, respectively. Current users of HRT at recruitment were more likely than never users to develop breast cancer (adjusted relative risk 1·66 [95% CI 1·58–1·75], p
language: eng
source: Alma/SFX Local Collection
identifier: ISSN: 0140-6736
fulltext: fulltext
issn:
  • 0140-6736
  • 1474-547X
url: Link


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subjectAdverse and side effects ; Age ; Breast cancer ; Breast Neoplasms - chemically induced ; Breast Neoplasms - epidemiology ; Breast Neoplasms - mortality ; Cancer ; England - epidemiology ; Epidemiology ; Estrogen ; Estrogen Replacement Therapy - adverse effects ; Estrogens ; Fatalities ; Female ; Follow-Up Studies ; Formulations ; Health risk assessment ; Health risks ; Hormone replacement therapy ; Hormone therapy ; Humans ; Incidence ; Invasiveness ; Mammography ; Mass Screening - statistics & numerical data ; Medical research ; Menopause ; Menstruation ; Middle Aged ; Mortality ; National Health Programs - statistics & numerical data ; Oncology, Experimental ; Registries - statistics & numerical data ; Risk ; Risk assessment ; Risk factors ; Skin cancer ; Statistics ; Therapy ; Tibolone ; United Kingdom ; Usage ; Women ; Womens health
ispartofThe Lancet (British edition), 2003, Vol.362 (9382), p.419-427
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