Raised plasma N-terminal pro-B-type natriuretic peptide concentrations predict mortality and cardiac disease in end-stage renal disease

Journal Title:	Heart (British Cardiac Society) 2006, Vol.92 (10), p.1518-1519
Main Author:	Sharma, R
Other Authors:	Gaze, D C , Pellerin, D , Mehta, R L , Gregson, H , Streather, C P , Collinson, P O , Brecker, S J D
Format:	Electronic Article
Language:	English
Subjects:	Abridged Index Medicus Acute coronary syndromes Age Analysis Biological and medical sciences Biomarkers Biomarkers - blood CAD cardiac troponin T Cardiology. Vascular system Cardiovascular disease Chronic kidney failure Complications and side effects Confidence intervals coronary artery disease Coronary vessels cTnT Diabetes dobutamine stress echocardiography DSE eGFR end-stage renal disease ESRD estimated glomerular filtration rate Female Heart attacks Heart diseases Heart Diseases - blood Heart Diseases - mortality Heart failure high sensitivity C reactive protein hs-CRP Humans Kidney diseases Kidney Failure, Chronic - blood Kidney Failure, Chronic - mortality left ventricular end systolic diameter LVESD Male Medical imaging Medical sciences Middle Aged Mortality Multivariate analysis N-terminal pro-B-type natriuretic peptide Natriuretic Peptide, Brain - metabolism Natriuretic peptides NT-proBNP Patient outcomes Peptide Fragments - metabolism Peptides Peritoneal dialysis Prospective Studies Scientific Letter Survival Analysis
Quelle:	Alma/SFX Local Collection
Publisher:	London: BMJ Publishing Group Ltd and British Cardiovascular Society
ID:	ISSN: 1355-6037
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title:	Raised plasma N-terminal pro-B-type natriuretic peptide concentrations predict mortality and cardiac disease in end-stage renal disease
format:	Article
creator:	Sharma, R Gaze, D C Pellerin, D Mehta, R L Gregson, H Streather, C P Collinson, P O Brecker, S J D
subjects:	Abridged Index Medicus Acute coronary syndromes Age Analysis Biological and medical sciences Biomarkers Biomarkers - blood CAD cardiac troponin T Cardiology. Vascular system Cardiovascular disease Chronic kidney failure Complications and side effects Confidence intervals coronary artery disease Coronary vessels cTnT Diabetes dobutamine stress echocardiography DSE eGFR end-stage renal disease ESRD estimated glomerular filtration rate Female Heart attacks Heart diseases Heart Diseases - blood Heart Diseases - mortality Heart failure high sensitivity C reactive protein hs-CRP Humans Kidney diseases Kidney Failure, Chronic - blood Kidney Failure, Chronic - mortality left ventricular end systolic diameter LVESD Male Medical imaging Medical sciences Middle Aged Mortality Multivariate analysis N-terminal pro-B-type natriuretic peptide Natriuretic Peptide, Brain - metabolism Natriuretic peptides NT-proBNP Patient outcomes Peptide Fragments - metabolism Peptides Peritoneal dialysis Prospective Studies Scientific Letter Survival Analysis
ispartof:	Heart (British Cardiac Society), 2006, Vol.92 (10), p.1518-1519
description:	Ea ratio 6.18 (2.17 to 9.94) 0.006 Significant CAD 5.87 (2.96 to 9.14) 0.02 CAD, coronary artery disease; DSE, dobutamine stress echocardiography; HR, hazard ratio; LV, left ventricular; LVEF, left ventricular ejection fraction; LVESD, left ventricular end systolic diameter; NT-proBNP, N-terminal pro-B-type natriuretic peptide. [...]multivariate analysis for mortality suggests these biomarkers act mainly as confounding factors. [...]no studies thus far have reported an improved outcome with medical or surgical intervention in patients with ESRD with raised cTnT or NT-proBNP.
language:	eng
source:	Alma/SFX Local Collection
identifier:	ISSN: 1355-6037
fulltext:	fulltext
issn:	1355-6037 1468-201X
url:	Link

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article

title

Raised plasma N-terminal pro-B-type natriuretic peptide concentrations predict mortality and cardiac disease in end-stage renal disease

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Alma/SFX Local Collection

creator

Sharma, R ; Gaze, D C ; Pellerin, D ; Mehta, R L ; Gregson, H ; Streather, C P ; Collinson, P O ; Brecker, S J D

creatorcontrib

Sharma, R ; Gaze, D C ; Pellerin, D ; Mehta, R L ; Gregson, H ; Streather, C P ; Collinson, P O ; Brecker, S J D

description

Ea ratio 6.18 (2.17 to 9.94) 0.006 Significant CAD 5.87 (2.96 to 9.14) 0.02 CAD, coronary artery disease; DSE, dobutamine stress echocardiography; HR, hazard ratio; LV, left ventricular; LVEF, left ventricular ejection fraction; LVESD, left ventricular end systolic diameter; NT-proBNP, N-terminal pro-B-type natriuretic peptide. [...]multivariate analysis for mortality suggests these biomarkers act mainly as confounding factors. [...]no studies thus far have reported an improved outcome with medical or surgical intervention in patients with ESRD with raised cTnT or NT-proBNP.

identifier

0	ISSN: 1355-6037
1	EISSN: 1468-201X
2	DOI: 10.1136/hrt.2005.082313
3	PMID: 16973808

language

eng

publisher

London: BMJ Publishing Group Ltd and British Cardiovascular Society

subject

Abridged Index Medicus ; Acute coronary syndromes ; Age ; Analysis ; Biological and medical sciences ; Biomarkers ; Biomarkers - blood ; CAD ; cardiac troponin T ; Cardiology. Vascular system ; Cardiovascular disease ; Chronic kidney failure ; Complications and side effects ; Confidence intervals ; coronary artery disease ; Coronary vessels ; cTnT ; Diabetes ; dobutamine stress echocardiography ; DSE ; eGFR ; end-stage renal disease ; ESRD ; estimated glomerular filtration rate ; Female ; Heart attacks ; Heart diseases ; Heart Diseases - blood ; Heart Diseases - mortality ; Heart failure ; high sensitivity C reactive protein ; hs-CRP ; Humans ; Kidney diseases ; Kidney Failure, Chronic - blood ; Kidney Failure, Chronic - mortality ; left ventricular end systolic diameter ; LVESD ; Male ; Medical imaging ; Medical sciences ; Middle Aged ; Mortality ; Multivariate analysis ; N-terminal pro-B-type natriuretic peptide ; Natriuretic Peptide, Brain - metabolism ; Natriuretic peptides ; NT-proBNP ; Patient outcomes ; Peptide Fragments - metabolism ; Peptides ; Peritoneal dialysis ; Prospective Studies ; Scientific Letter ; Survival Analysis

ispartof

Heart (British Cardiac Society), 2006, Vol.92 (10), p.1518-1519

rights

0	Copyright 2006 by Heart
1	2006 INIST-CNRS
2	Copyright: 2006 Copyright 2006 by Heart
3	Copyright © 2006 BMJ Publishing Group and British Cardiovascular Society

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0	Sharma, R
1	Gaze, D C
2	Pellerin, D
3	Mehta, R L
4	Gregson, H
5	Streather, C P
6	Collinson, P O
7	Brecker, S J D

title

0	Raised plasma N-terminal pro-B-type natriuretic peptide concentrations predict mortality and cardiac disease in end-stage renal disease
1	Heart (British Cardiac Society)

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0	Abridged Index Medicus
1	Acute coronary syndromes
2	Age
3	Analysis
4	Biological and medical sciences
5	Biomarkers
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7	CAD
8	cardiac troponin T
9	Cardiology. Vascular system
10	Cardiovascular disease
11	Chronic kidney failure
12	Complications and side effects
13	Confidence intervals
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17	Diabetes
18	dobutamine stress echocardiography
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25	Heart attacks
26	Heart diseases
27	Heart Diseases - blood
28	Heart Diseases - mortality
29	Heart failure
30	high sensitivity C reactive protein
31	hs-CRP
32	Humans
33	Kidney diseases
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36	left ventricular end systolic diameter
37	LVESD
38	Male
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40	Medical sciences
41	Middle Aged
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43	Multivariate analysis
44	N-terminal pro-B-type natriuretic peptide
45	Natriuretic Peptide, Brain - metabolism
46	Natriuretic peptides
47	NT-proBNP
48	Patient outcomes
49	Peptide Fragments - metabolism
50	Peptides
51	Peritoneal dialysis
52	Prospective Studies
53	Scientific Letter
54	Survival Analysis

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2	Pellerin, D
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creationdate	200610
title	Raised plasma N-terminal pro-B-type natriuretic peptide concentrations predict mortality and cardiac disease in end-stage renal disease
author	Sharma, R ; Gaze, D C ; Pellerin, D ; Mehta, R L ; Gregson, H ; Streather, C P ; Collinson, P O ; Brecker, S J D

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creationdate

2006

topic

0	Abridged Index Medicus
1	Acute coronary syndromes
2	Age
3	Analysis
4	Biological and medical sciences
5	Biomarkers
6	Biomarkers - blood
7	CAD
8	cardiac troponin T
9	Cardiology. Vascular system
10	Cardiovascular disease
11	Chronic kidney failure
12	Complications and side effects
13	Confidence intervals
14	coronary artery disease
15	Coronary vessels
16	cTnT
17	Diabetes
18	dobutamine stress echocardiography
19	DSE
20	eGFR
21	end-stage renal disease
22	ESRD
23	estimated glomerular filtration rate
24	Female
25	Heart attacks
26	Heart diseases
27	Heart Diseases - blood
28	Heart Diseases - mortality
29	Heart failure
30	high sensitivity C reactive protein
31	hs-CRP
32	Humans
33	Kidney diseases
34	Kidney Failure, Chronic - blood
35	Kidney Failure, Chronic - mortality
36	left ventricular end systolic diameter
37	LVESD
38	Male
39	Medical imaging
40	Medical sciences
41	Middle Aged
42	Mortality
43	Multivariate analysis
44	N-terminal pro-B-type natriuretic peptide
45	Natriuretic Peptide, Brain - metabolism
46	Natriuretic peptides
47	NT-proBNP
48	Patient outcomes
49	Peptide Fragments - metabolism
50	Peptides
51	Peritoneal dialysis
52	Prospective Studies
53	Scientific Letter
54	Survival Analysis

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0	Sharma, R
1	Gaze, D C
2	Pellerin, D
3	Mehta, R L
4	Gregson, H
5	Streather, C P
6	Collinson, P O
7	Brecker, S J D

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jtitle

Heart (British Cardiac Society)

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fulltext	fulltext

addata

0	Sharma, R
1	Gaze, D C
2	Pellerin, D
3	Mehta, R L
4	Gregson, H
5	Streather, C P
6	Collinson, P O
7	Brecker, S J D

format

journal

genre

article

ristype

JOUR

atitle

Raised plasma N-terminal pro-B-type natriuretic peptide concentrations predict mortality and cardiac disease in end-stage renal disease

jtitle

Heart (British Cardiac Society)

addtitle

Heart

date

2006-10

risdate

2006

volume

issue

spage

1518

epage

1519

pages

1518-1519

issn

1355-6037

eissn

1468-201X

notes

Correspondence to:  Dr Rajan Sharma  Department of Cardiology, Southampton University Hospital, Tremona Road, Southampton SO16 6YD, UK; rajdoc.Sharma@tiscali.co.uk

abstract

cop

London

pub

BMJ Publishing Group Ltd and British Cardiovascular Society

pmid

16973808

doi

10.1136/hrt.2005.082313

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Raised plasma N-terminal pro-B-type natriuretic peptide concentrations predict mortality and cardiac disease in end-stage renal disease