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Heart failure with a normal ejection fraction

Nearly half of patients with symptoms of heart failure are found to have a normal left ventricular (LV) ejection fraction. This has variously been labelled as diastolic heart failure, heart failure with preserved LV function or heart failure with a normal ejection fraction (HFNEF). As recent studies... Full description

Journal Title: Heart (British Cardiac Society) 2007, Vol.93 (2), p.155-158
Main Author: Sanderson, J E
Format: Electronic Article Electronic Article
Language: English
Subjects:
AF
Age
LV
SHF
Quelle: Alma/SFX Local Collection
Publisher: London: BMJ Publishing Group Ltd and British Cardiovascular Society
ID: ISSN: 1355-6037
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recordid: cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1861394
title: Heart failure with a normal ejection fraction
format: Article
creator:
  • Sanderson, J E
subjects:
  • Abridged Index Medicus
  • AF
  • Age
  • Aged
  • atrial fibrillation
  • Biological and medical sciences
  • Candesartan in Heart failure: Assessment of Reduction in Mortality and morbidity
  • Cardiac output
  • Cardiology. Vascular system
  • Care and treatment
  • CHARM
  • Clinical trials
  • Development and progression
  • Diabetes
  • Diastole
  • Echocardiography, Doppler
  • Epidemiology
  • Evaluation
  • Female
  • Fractions
  • Heart
  • Heart attacks
  • Heart failure
  • Heart Failure - diagnosis
  • Heart Failure - etiology
  • Heart Failure - physiopathology
  • heart failure with a normal ejection fraction
  • Heart failure, cardiogenic pulmonary edema, cardiac enlargement
  • Heart Review
  • HFNEF
  • Hospitals
  • Humans
  • Hypertension
  • Hypertension - complications
  • Hypertension - physiopathology
  • Kidney Failure, Chronic - complications
  • Kidney Failure, Chronic - physiopathology
  • left ventricular
  • left ventricular ejection fraction
  • LV
  • LVEF
  • Male
  • Medical sciences
  • Middle Aged
  • Morbidity
  • Mortality
  • Myocardial Infarction - complications
  • Myocardial Infarction - physiopathology
  • Older people
  • Patients
  • Physiology
  • Population
  • SHF
  • Stroke Volume - physiology
  • Studies
  • systolic heart failure
  • Velocity
  • Ventricular Remodeling
ispartof: Heart (British Cardiac Society), 2007, Vol.93 (2), p.155-158
description: Nearly half of patients with symptoms of heart failure are found to have a normal left ventricular (LV) ejection fraction. This has variously been labelled as diastolic heart failure, heart failure with preserved LV function or heart failure with a normal ejection fraction (HFNEF). As recent studies have shown that systolic function is not entirely normal in these patients, HFNEF is the preferred term. The epidemiology, aetiology and possible pathophysiology of this contentious condition are reviewed. The importance of the remodelling process in determining whether a patient presents with systolic heart failure or HFNEF is emphasised and this can be used to classify patients in a more rational manner.
language: eng
source: Alma/SFX Local Collection
identifier: ISSN: 1355-6037
fulltext: fulltext
issn:
  • 1355-6037
  • 1468-201X
url: Link


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descriptionNearly half of patients with symptoms of heart failure are found to have a normal left ventricular (LV) ejection fraction. This has variously been labelled as diastolic heart failure, heart failure with preserved LV function or heart failure with a normal ejection fraction (HFNEF). As recent studies have shown that systolic function is not entirely normal in these patients, HFNEF is the preferred term. The epidemiology, aetiology and possible pathophysiology of this contentious condition are reviewed. The importance of the remodelling process in determining whether a patient presents with systolic heart failure or HFNEF is emphasised and this can be used to classify patients in a more rational manner.
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subjectAbridged Index Medicus ; AF ; Age ; Aged ; atrial fibrillation ; Biological and medical sciences ; Candesartan in Heart failure: Assessment of Reduction in Mortality and morbidity ; Cardiac output ; Cardiology. Vascular system ; Care and treatment ; CHARM ; Clinical trials ; Development and progression ; Diabetes ; Diastole ; Echocardiography, Doppler ; Epidemiology ; Evaluation ; Female ; Fractions ; Heart ; Heart attacks ; Heart failure ; Heart Failure - diagnosis ; Heart Failure - etiology ; Heart Failure - physiopathology ; heart failure with a normal ejection fraction ; Heart failure, cardiogenic pulmonary edema, cardiac enlargement ; Heart Review ; HFNEF ; Hospitals ; Humans ; Hypertension ; Hypertension - complications ; Hypertension - physiopathology ; Kidney Failure, Chronic - complications ; Kidney Failure, Chronic - physiopathology ; left ventricular ; left ventricular ejection fraction ; LV ; LVEF ; Male ; Medical sciences ; Middle Aged ; Morbidity ; Mortality ; Myocardial Infarction - complications ; Myocardial Infarction - physiopathology ; Older people ; Patients ; Physiology ; Population ; SHF ; Stroke Volume - physiology ; Studies ; systolic heart failure ; Velocity ; Ventricular Remodeling
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descriptionNearly half of patients with symptoms of heart failure are found to have a normal left ventricular (LV) ejection fraction. This has variously been labelled as diastolic heart failure, heart failure with preserved LV function or heart failure with a normal ejection fraction (HFNEF). As recent studies have shown that systolic function is not entirely normal in these patients, HFNEF is the preferred term. The epidemiology, aetiology and possible pathophysiology of this contentious condition are reviewed. The importance of the remodelling process in determining whether a patient presents with systolic heart failure or HFNEF is emphasised and this can be used to classify patients in a more rational manner.
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5Biological and medical sciences
6Candesartan in Heart failure: Assessment of Reduction in Mortality and morbidity
7Cardiac output
8Cardiology. Vascular system
9Care and treatment
10CHARM
11Clinical trials
12Development and progression
13Diabetes
14Diastole
15Echocardiography, Doppler
16Epidemiology
17Evaluation
18Female
19Fractions
20Heart
21Heart attacks
22Heart failure
23Heart Failure - diagnosis
24Heart Failure - etiology
25Heart Failure - physiopathology
26heart failure with a normal ejection fraction
27Heart failure, cardiogenic pulmonary edema, cardiac enlargement
28Heart Review
29HFNEF
30Hospitals
31Humans
32Hypertension
33Hypertension - complications
34Hypertension - physiopathology
35Kidney Failure, Chronic - complications
36Kidney Failure, Chronic - physiopathology
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40LVEF
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42Medical sciences
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44Morbidity
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46Myocardial Infarction - complications
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48Older people
49Patients
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52SHF
53Stroke Volume - physiology
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1AF
2Age
3Aged
4atrial fibrillation
5Biological and medical sciences
6Candesartan in Heart failure: Assessment of Reduction in Mortality and morbidity
7Cardiac output
8Cardiology. Vascular system
9Care and treatment
10CHARM
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12Development and progression
13Diabetes
14Diastole
15Echocardiography, Doppler
16Epidemiology
17Evaluation
18Female
19Fractions
20Heart
21Heart attacks
22Heart failure
23Heart Failure - diagnosis
24Heart Failure - etiology
25Heart Failure - physiopathology
26heart failure with a normal ejection fraction
27Heart failure, cardiogenic pulmonary edema, cardiac enlargement
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34Hypertension - physiopathology
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38left ventricular ejection fraction
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40LVEF
41Male
42Medical sciences
43Middle Aged
44Morbidity
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46Myocardial Infarction - complications
47Myocardial Infarction - physiopathology
48Older people
49Patients
50Physiology
51Population
52SHF
53Stroke Volume - physiology
54Studies
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atitleHeart failure with a normal ejection fraction
jtitleHeart (British Cardiac Society)
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date2007-02
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volume93
issue2
spage155
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pages155-158
issn1355-6037
eissn1468-201X
notesCorrespondence to:
 Professor John Sanderson
 Department of Cardiology, University Hospital of North Staffordshire NHS Trust, City General Hospital, Stoke-on-Trent ST4 6QG, UK; John.Sanderson@uhns.nhs.uk
abstractNearly half of patients with symptoms of heart failure are found to have a normal left ventricular (LV) ejection fraction. This has variously been labelled as diastolic heart failure, heart failure with preserved LV function or heart failure with a normal ejection fraction (HFNEF). As recent studies have shown that systolic function is not entirely normal in these patients, HFNEF is the preferred term. The epidemiology, aetiology and possible pathophysiology of this contentious condition are reviewed. The importance of the remodelling process in determining whether a patient presents with systolic heart failure or HFNEF is emphasised and this can be used to classify patients in a more rational manner.
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pubBMJ Publishing Group Ltd and British Cardiovascular Society
pmid16387829
doi10.1136/hrt.2005.074187
oafree_for_read