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Restenosis after elective coronary balloon angioplasty in patients with end stage renal disease: a case-control study using quantitative coronary angiography

Objective To assess the rate of angiographic restenosis in patients with end stage renal disease after elective coronary angioplasty. Design A retrospective case-control study of 20 patients with end stage renal disease and 20 sex and age matched controls without renal disease, who had undergone pri... Full description

Journal Title: Heart (British Cardiac Society) 1997, Vol.78 (4), p.337-342
Main Author: Schoebel, Frank-Chris
Other Authors: Gradaus, Frank , Ivens, Katrin , Heering, Peter , Jax, Thomas Walter , Grabensee, Bernd , Strauer, Bodo-Eckehard , Leschke, Matthias
Format: Electronic Article Electronic Article
Language: English
Subjects:
Quelle: Alma/SFX Local Collection
Publisher: London: BMJ Publishing Group Ltd and British Cardiovascular Society
ID: ISSN: 1355-6037
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title: Restenosis after elective coronary balloon angioplasty in patients with end stage renal disease: a case-control study using quantitative coronary angiography
format: Article
creator:
  • Schoebel, Frank-Chris
  • Gradaus, Frank
  • Ivens, Katrin
  • Heering, Peter
  • Jax, Thomas Walter
  • Grabensee, Bernd
  • Strauer, Bodo-Eckehard
  • Leschke, Matthias
subjects:
  • Abridged Index Medicus
  • Angioplasty
  • Angioplasty, Balloon, Coronary
  • Biological and medical sciences
  • Cardiology. Vascular system
  • Cardiovascular disease
  • Case-Control Studies
  • Cholesterol
  • Cholesterol - blood
  • Cholesterol, HDL - blood
  • Coronary Angiography
  • coronary angioplasty
  • coronary artery disease
  • Coronary Disease - complications
  • Coronary Disease - diagnostic imaging
  • Coronary Disease - therapy
  • Coronary heart disease
  • Coronary vessels
  • Discriminant analysis
  • Fibrinogen - metabolism
  • Heart
  • Heart attacks
  • Humans
  • Intervention
  • Kidney diseases
  • Kidney Failure, Chronic - blood
  • Kidney Failure, Chronic - complications
  • Kidney Failure, Chronic - diagnostic imaging
  • Male
  • Medical imaging
  • Medical sciences
  • Middle Aged
  • Morphology
  • Mortality
  • Papers
  • Population
  • Recurrence
  • renal disease
  • restenosis
  • Retrospective Studies
  • Risk factors
  • Stents
  • Thrombosis
  • Triglycerides - blood
ispartof: Heart (British Cardiac Society), 1997, Vol.78 (4), p.337-342
description: Objective To assess the rate of angiographic restenosis in patients with end stage renal disease after elective coronary angioplasty. Design A retrospective case-control study of 20 patients with end stage renal disease and 20 sex and age matched controls without renal disease, who had undergone primarily successful coronary angioplasty. Control coronary angiography was performed regardless of worsening or renewed incidence of anginal symptoms. Main outcome measures Group comparison of coronary morphology, as evaluated by quantitative coronary angiography, and of cardiovascular risk factors. Results The rate of angiographic restenosis was 60% in patients with renal disease and 35% in controls. In patients with end stage renal disease the following differences (mean (SD) were found versus controls: raised plasma fibrinogen (483 (101)v 326 (62) mg/dl, p 
language: eng
source: Alma/SFX Local Collection
identifier: ISSN: 1355-6037
fulltext: fulltext
issn:
  • 1355-6037
  • 1468-201X
url: Link


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titleRestenosis after elective coronary balloon angioplasty in patients with end stage renal disease: a case-control study using quantitative coronary angiography
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creatorSchoebel, Frank-Chris ; Gradaus, Frank ; Ivens, Katrin ; Heering, Peter ; Jax, Thomas Walter ; Grabensee, Bernd ; Strauer, Bodo-Eckehard ; Leschke, Matthias
creatorcontribSchoebel, Frank-Chris ; Gradaus, Frank ; Ivens, Katrin ; Heering, Peter ; Jax, Thomas Walter ; Grabensee, Bernd ; Strauer, Bodo-Eckehard ; Leschke, Matthias
descriptionObjective To assess the rate of angiographic restenosis in patients with end stage renal disease after elective coronary angioplasty. Design A retrospective case-control study of 20 patients with end stage renal disease and 20 sex and age matched controls without renal disease, who had undergone primarily successful coronary angioplasty. Control coronary angiography was performed regardless of worsening or renewed incidence of anginal symptoms. Main outcome measures Group comparison of coronary morphology, as evaluated by quantitative coronary angiography, and of cardiovascular risk factors. Results The rate of angiographic restenosis was 60% in patients with renal disease and 35% in controls. In patients with end stage renal disease the following differences (mean (SD) were found versus controls: raised plasma fibrinogen (483 (101)v 326 (62) mg/dl, p < 0.001); raised plasma triglyceride (269 (163) v 207 (176) mg/dl, p < 0.01); smaller diameter of the coronary reference segment (2.59 (0.87) v 2.90 (0.55) mm, p < 0.10); smaller minimum luminal diameter of the dilated stenosis (0.77 (0.46)v 0.97 (0.27) mm, p < 0.05). Discriminant analysis showed that minimum luminal diameter before angioplasty (r = −0.79) and fibrinogen (r = +0.34) had the highest statistical association with restenosis. Conclusions The high rate of angiographic restenosis in patients with end stage renal disease seems to be related to the size of the vessel dilated and to an increased prothrombotic risk, as indicated by higher fibrinogen concentrations.
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0ISSN: 1355-6037
1EISSN: 1468-201X
2DOI: 10.1136/hrt.78.4.337
3PMID: 9404246
languageeng
publisherLondon: BMJ Publishing Group Ltd and British Cardiovascular Society
subjectAbridged Index Medicus ; Angioplasty ; Angioplasty, Balloon, Coronary ; Biological and medical sciences ; Cardiology. Vascular system ; Cardiovascular disease ; Case-Control Studies ; Cholesterol ; Cholesterol - blood ; Cholesterol, HDL - blood ; Coronary Angiography ; coronary angioplasty ; coronary artery disease ; Coronary Disease - complications ; Coronary Disease - diagnostic imaging ; Coronary Disease - therapy ; Coronary heart disease ; Coronary vessels ; Discriminant analysis ; Fibrinogen - metabolism ; Heart ; Heart attacks ; Humans ; Intervention ; Kidney diseases ; Kidney Failure, Chronic - blood ; Kidney Failure, Chronic - complications ; Kidney Failure, Chronic - diagnostic imaging ; Male ; Medical imaging ; Medical sciences ; Middle Aged ; Morphology ; Mortality ; Papers ; Population ; Recurrence ; renal disease ; restenosis ; Retrospective Studies ; Risk factors ; Stents ; Thrombosis ; Triglycerides - blood
ispartofHeart (British Cardiac Society), 1997, Vol.78 (4), p.337-342
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0Schoebel, Frank-Chris
1Gradaus, Frank
2Ivens, Katrin
3Heering, Peter
4Jax, Thomas Walter
5Grabensee, Bernd
6Strauer, Bodo-Eckehard
7Leschke, Matthias
title
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1Heart (British Cardiac Society)
addtitleHeart
descriptionObjective To assess the rate of angiographic restenosis in patients with end stage renal disease after elective coronary angioplasty. Design A retrospective case-control study of 20 patients with end stage renal disease and 20 sex and age matched controls without renal disease, who had undergone primarily successful coronary angioplasty. Control coronary angiography was performed regardless of worsening or renewed incidence of anginal symptoms. Main outcome measures Group comparison of coronary morphology, as evaluated by quantitative coronary angiography, and of cardiovascular risk factors. Results The rate of angiographic restenosis was 60% in patients with renal disease and 35% in controls. In patients with end stage renal disease the following differences (mean (SD) were found versus controls: raised plasma fibrinogen (483 (101)v 326 (62) mg/dl, p < 0.001); raised plasma triglyceride (269 (163) v 207 (176) mg/dl, p < 0.01); smaller diameter of the coronary reference segment (2.59 (0.87) v 2.90 (0.55) mm, p < 0.10); smaller minimum luminal diameter of the dilated stenosis (0.77 (0.46)v 0.97 (0.27) mm, p < 0.05). Discriminant analysis showed that minimum luminal diameter before angioplasty (r = −0.79) and fibrinogen (r = +0.34) had the highest statistical association with restenosis. Conclusions The high rate of angiographic restenosis in patients with end stage renal disease seems to be related to the size of the vessel dilated and to an increased prothrombotic risk, as indicated by higher fibrinogen concentrations.
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0Abridged Index Medicus
1Angioplasty
2Angioplasty, Balloon, Coronary
3Biological and medical sciences
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5Cardiovascular disease
6Case-Control Studies
7Cholesterol
8Cholesterol - blood
9Cholesterol, HDL - blood
10Coronary Angiography
11coronary angioplasty
12coronary artery disease
13Coronary Disease - complications
14Coronary Disease - diagnostic imaging
15Coronary Disease - therapy
16Coronary heart disease
17Coronary vessels
18Discriminant analysis
19Fibrinogen - metabolism
20Heart
21Heart attacks
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23Intervention
24Kidney diseases
25Kidney Failure, Chronic - blood
26Kidney Failure, Chronic - complications
27Kidney Failure, Chronic - diagnostic imaging
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29Medical imaging
30Medical sciences
31Middle Aged
32Morphology
33Mortality
34Papers
35Population
36Recurrence
37renal disease
38restenosis
39Retrospective Studies
40Risk factors
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42Thrombosis
43Triglycerides - blood
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0Schoebel, Frank-Chris
1Gradaus, Frank
2Ivens, Katrin
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7Leschke, Matthias
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atitleRestenosis after elective coronary balloon angioplasty in patients with end stage renal disease: a case-control study using quantitative coronary angiography
jtitleHeart (British Cardiac Society)
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volume78
issue4
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pages337-342
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abstractObjective To assess the rate of angiographic restenosis in patients with end stage renal disease after elective coronary angioplasty. Design A retrospective case-control study of 20 patients with end stage renal disease and 20 sex and age matched controls without renal disease, who had undergone primarily successful coronary angioplasty. Control coronary angiography was performed regardless of worsening or renewed incidence of anginal symptoms. Main outcome measures Group comparison of coronary morphology, as evaluated by quantitative coronary angiography, and of cardiovascular risk factors. Results The rate of angiographic restenosis was 60% in patients with renal disease and 35% in controls. In patients with end stage renal disease the following differences (mean (SD) were found versus controls: raised plasma fibrinogen (483 (101)v 326 (62) mg/dl, p < 0.001); raised plasma triglyceride (269 (163) v 207 (176) mg/dl, p < 0.01); smaller diameter of the coronary reference segment (2.59 (0.87) v 2.90 (0.55) mm, p < 0.10); smaller minimum luminal diameter of the dilated stenosis (0.77 (0.46)v 0.97 (0.27) mm, p < 0.05). Discriminant analysis showed that minimum luminal diameter before angioplasty (r = −0.79) and fibrinogen (r = +0.34) had the highest statistical association with restenosis. Conclusions The high rate of angiographic restenosis in patients with end stage renal disease seems to be related to the size of the vessel dilated and to an increased prothrombotic risk, as indicated by higher fibrinogen concentrations.
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