schliessen

Filtern

 

Bibliotheken

Geographic HIV Type 1 Subtype Distribution in Rakai District, Uganda

To analyze HIV-1 subtype distribution, sequence analysis was performed on serum specimens obtained in 1994 from the Rakai Health Sciences community cohort in Uganda. Portions of gag -p24 and env -gp41 were sequenced and HIV subtype was determined for 773 subjects residing in 10 community clusters in... Full description

Journal Title: AIDS research and human retroviruses 2009, Vol.25 (10), p.145-1048
Main Author: Collinson-Streng, Aleisha N.
Other Authors: Redd, Andrew D. , Sewankambo, Nelson K. , Serwadda, David , Rezapour, Mona , Lamers, Susanna L. , Gray, Ronald H. , Wawer, Maria J. , Quinn, Thomas C. , Laeyendecker, Oliver
Format: Electronic Article Electronic Article
Language: English
Subjects:
Quelle: Alma/SFX Local Collection
Publisher: New Rochelle, NY: Mary Ann Liebert, Inc
ID: ISSN: 0889-2229
Zum Text:
SendSend as email Add to Book BagAdd to Book Bag
Staff View
recordid: cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2785855
title: Geographic HIV Type 1 Subtype Distribution in Rakai District, Uganda
format: Article
creator:
  • Collinson-Streng, Aleisha N.
  • Redd, Andrew D.
  • Sewankambo, Nelson K.
  • Serwadda, David
  • Rezapour, Mona
  • Lamers, Susanna L.
  • Gray, Ronald H.
  • Wawer, Maria J.
  • Quinn, Thomas C.
  • Laeyendecker, Oliver
subjects:
  • Adolescent
  • Adult
  • AIDS/HIV
  • Animals
  • Biological and medical sciences
  • Biological diversity
  • Distribution
  • Female
  • Fundamental and applied biological sciences. Psychology
  • gag Gene Products, Human Immunodeficiency Virus - genetics
  • Genetic aspects
  • Genotype
  • Geography
  • HIV (Viruses)
  • HIV Envelope Protein gp41 - genetics
  • HIV infection
  • HIV Infections - epidemiology
  • HIV Infections - virology
  • HIV-1 - classification
  • HIV-1 - genetics
  • HIV-1 - isolation & purification
  • Human immunodeficiency virus 1
  • Human viral diseases
  • Humans
  • Infectious diseases
  • Male
  • Medical sciences
  • Microbiology
  • Middle Aged
  • Miscellaneous
  • Molecular Sequence Data
  • Retrovirus
  • Rural Population
  • Sequence Analysis, DNA
  • Sequence Notes
  • Uganda - epidemiology
  • Viral diseases
  • Virology
  • Young Adult
ispartof: AIDS research and human retroviruses, 2009, Vol.25 (10), p.145-1048
description: To analyze HIV-1 subtype distribution, sequence analysis was performed on serum specimens obtained in 1994 from the Rakai Health Sciences community cohort in Uganda. Portions of gag -p24 and env -gp41 were sequenced and HIV subtype was determined for 773 subjects residing in 10 community clusters in rural Uganda. Subtypes A (17%) and D (70%) were the most common strains in the population. Subtype distribution varied by geographic region with significantly more subtype A in northern community clusters compared with southern clusters (21% vs. 8%, p  
language: eng
source: Alma/SFX Local Collection
identifier: ISSN: 0889-2229
fulltext: fulltext
issn:
  • 0889-2229
  • 1931-8405
url: Link


@attributes
NO1
SEARCH_ENGINEprimo_central_multiple_fe
SEARCH_ENGINE_TYPEPrimo Central Search Engine
RANK2.2459664
LOCALfalse
PrimoNMBib
record
control
sourceidgale_pubme
recordidTN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2785855
sourceformatXML
sourcesystemPC
galeidA211555011
sourcerecordidA211555011
originalsourceidFETCH-LOGICAL-1696t-fcd1c2f156372f0059bd9bc1cafe8bde4fcecbaa9d8ff8023583366bba5a49ad3
addsrcrecordideNqFkttrFDEUxgdR7Fp99FUGRH1x1lwmM8mLUFrtFgqCtr6Gk9s2OpusyazQ_94MO1RXvJCHhJPf952T8FXVU4yWGHHxBrxZEoTEEmHS36sWWFDc8Bax-9UCcS4aQog4qh7l_AUVjBD2sDrCgiPaY7qozs5tXCfY3nhdry4-11e3W1vj-tNOjdPpzOcxebUbfQy1D_VH-Ap-rurxdX29hmDgcfXAwZDtk3k_rq7fv7s6XTWXH84vTk8uG9yJbmycNlgTh1lHe-IQYkIZoTTW4CxXxrZOW60AhOHOcUQo45R2nVLAoBVg6HH1du-73amNNdqGMcEgt8lvIN3KCF4e3gR_I9fxuyQ9Z5yxYrDaG8StDeCTPdCaYEcZjSRdL4EpBr1j1BnhEFcMA8EIKOXQ8r7lxerVPEuK33Y2j3Ljs7bDAMHGXZZ9GR11XYsK-fKfJMEEt4J3BXy-B9cwWOmDi-UReoLlCcGYMYYwLtTyD1RZxm68jsE6X-oHgmYv0CnmnKy7ezRGcsqQLBmSU4bklKHCP_v1l3_Sc2gK8GIGIGsYXIKgfb7jCEG87-jUmP7WWPsRpiiVif3w1_azajKDEAZvlU3jf4b-AQ8D7tc
sourcetypeOpen Access Repository
isCDItrue
recordtypearticle
pqid21214986
display
typearticle
titleGeographic HIV Type 1 Subtype Distribution in Rakai District, Uganda
sourceAlma/SFX Local Collection
creatorCollinson-Streng, Aleisha N. ; Redd, Andrew D. ; Sewankambo, Nelson K. ; Serwadda, David ; Rezapour, Mona ; Lamers, Susanna L. ; Gray, Ronald H. ; Wawer, Maria J. ; Quinn, Thomas C. ; Laeyendecker, Oliver
creatorcontribCollinson-Streng, Aleisha N. ; Redd, Andrew D. ; Sewankambo, Nelson K. ; Serwadda, David ; Rezapour, Mona ; Lamers, Susanna L. ; Gray, Ronald H. ; Wawer, Maria J. ; Quinn, Thomas C. ; Laeyendecker, Oliver
descriptionTo analyze HIV-1 subtype distribution, sequence analysis was performed on serum specimens obtained in 1994 from the Rakai Health Sciences community cohort in Uganda. Portions of gag -p24 and env -gp41 were sequenced and HIV subtype was determined for 773 subjects residing in 10 community clusters in rural Uganda. Subtypes A (17%) and D (70%) were the most common strains in the population. Subtype distribution varied by geographic region with significantly more subtype A in northern community clusters compared with southern clusters (21% vs. 8%, p  < 0.001) and more subtype D in southern clusters compared with northern clusters (78% vs. 65%, p  < 0.008). These data illustrate the geographic complexity of subtype variation, which has important implications for HIV-1 vaccine design.
identifier
0ISSN: 0889-2229
1EISSN: 1931-8405
2DOI: 10.1089/aid.2009.0127
3PMID: 19803713
4CODEN: ARHRE7
languageeng
publisherNew Rochelle, NY: Mary Ann Liebert, Inc
subjectAdolescent ; Adult ; AIDS/HIV ; Animals ; Biological and medical sciences ; Biological diversity ; Distribution ; Female ; Fundamental and applied biological sciences. Psychology ; gag Gene Products, Human Immunodeficiency Virus - genetics ; Genetic aspects ; Genotype ; Geography ; HIV (Viruses) ; HIV Envelope Protein gp41 - genetics ; HIV infection ; HIV Infections - epidemiology ; HIV Infections - virology ; HIV-1 - classification ; HIV-1 - genetics ; HIV-1 - isolation & purification ; Human immunodeficiency virus 1 ; Human viral diseases ; Humans ; Infectious diseases ; Male ; Medical sciences ; Microbiology ; Middle Aged ; Miscellaneous ; Molecular Sequence Data ; Retrovirus ; Rural Population ; Sequence Analysis, DNA ; Sequence Notes ; Uganda - epidemiology ; Viral diseases ; Virology ; Young Adult
ispartofAIDS research and human retroviruses, 2009, Vol.25 (10), p.145-1048
rights
02009, Mary Ann Liebert, Inc.
12009 INIST-CNRS
2COPYRIGHT 2009 Mary Ann Liebert, Inc.
3Copyright 2009, Mary Ann Liebert, Inc.
lds50peer_reviewed
oafree_for_read
citedbyFETCH-LOGICAL-1696t-fcd1c2f156372f0059bd9bc1cafe8bde4fcecbaa9d8ff8023583366bba5a49ad3
citesFETCH-LOGICAL-1696t-fcd1c2f156372f0059bd9bc1cafe8bde4fcecbaa9d8ff8023583366bba5a49ad3
links
openurl$$Topenurl_article
openurlfulltext$$Topenurlfull_article
thumbnail$$Usyndetics_thumb_exl
backlink
0$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=22087631$$DView record in Pascal Francis
1$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19803713$$D View this record in MEDLINE/PubMed
search
creatorcontrib
0Collinson-Streng, Aleisha N.
1Redd, Andrew D.
2Sewankambo, Nelson K.
3Serwadda, David
4Rezapour, Mona
5Lamers, Susanna L.
6Gray, Ronald H.
7Wawer, Maria J.
8Quinn, Thomas C.
9Laeyendecker, Oliver
title
0Geographic HIV Type 1 Subtype Distribution in Rakai District, Uganda
1AIDS research and human retroviruses
addtitleAIDS Res Hum Retroviruses
descriptionTo analyze HIV-1 subtype distribution, sequence analysis was performed on serum specimens obtained in 1994 from the Rakai Health Sciences community cohort in Uganda. Portions of gag -p24 and env -gp41 were sequenced and HIV subtype was determined for 773 subjects residing in 10 community clusters in rural Uganda. Subtypes A (17%) and D (70%) were the most common strains in the population. Subtype distribution varied by geographic region with significantly more subtype A in northern community clusters compared with southern clusters (21% vs. 8%, p  < 0.001) and more subtype D in southern clusters compared with northern clusters (78% vs. 65%, p  < 0.008). These data illustrate the geographic complexity of subtype variation, which has important implications for HIV-1 vaccine design.
subject
0Adolescent
1Adult
2AIDS/HIV
3Animals
4Biological and medical sciences
5Biological diversity
6Distribution
7Female
8Fundamental and applied biological sciences. Psychology
9gag Gene Products, Human Immunodeficiency Virus - genetics
10Genetic aspects
11Genotype
12Geography
13HIV (Viruses)
14HIV Envelope Protein gp41 - genetics
15HIV infection
16HIV Infections - epidemiology
17HIV Infections - virology
18HIV-1 - classification
19HIV-1 - genetics
20HIV-1 - isolation & purification
21Human immunodeficiency virus 1
22Human viral diseases
23Humans
24Infectious diseases
25Male
26Medical sciences
27Microbiology
28Middle Aged
29Miscellaneous
30Molecular Sequence Data
31Retrovirus
32Rural Population
33Sequence Analysis, DNA
34Sequence Notes
35Uganda - epidemiology
36Viral diseases
37Virology
38Young Adult
issn
00889-2229
11931-8405
fulltexttrue
rsrctypearticle
creationdate2009
recordtypearticle
recordideNqFkttrFDEUxgdR7Fp99FUGRH1x1lwmM8mLUFrtFgqCtr6Gk9s2OpusyazQ_94MO1RXvJCHhJPf952T8FXVU4yWGHHxBrxZEoTEEmHS36sWWFDc8Bax-9UCcS4aQog4qh7l_AUVjBD2sDrCgiPaY7qozs5tXCfY3nhdry4-11e3W1vj-tNOjdPpzOcxebUbfQy1D_VH-Ap-rurxdX29hmDgcfXAwZDtk3k_rq7fv7s6XTWXH84vTk8uG9yJbmycNlgTh1lHe-IQYkIZoTTW4CxXxrZOW60AhOHOcUQo45R2nVLAoBVg6HH1du-73amNNdqGMcEgt8lvIN3KCF4e3gR_I9fxuyQ9Z5yxYrDaG8StDeCTPdCaYEcZjSRdL4EpBr1j1BnhEFcMA8EIKOXQ8r7lxerVPEuK33Y2j3Ljs7bDAMHGXZZ9GR11XYsK-fKfJMEEt4J3BXy-B9cwWOmDi-UReoLlCcGYMYYwLtTyD1RZxm68jsE6X-oHgmYv0CnmnKy7ezRGcsqQLBmSU4bklKHCP_v1l3_Sc2gK8GIGIGsYXIKgfb7jCEG87-jUmP7WWPsRpiiVif3w1_azajKDEAZvlU3jf4b-AQ8D7tc
startdate20091001
enddate20091001
creator
0Collinson-Streng, Aleisha N.
1Redd, Andrew D.
2Sewankambo, Nelson K.
3Serwadda, David
4Rezapour, Mona
5Lamers, Susanna L.
6Gray, Ronald H.
7Wawer, Maria J.
8Quinn, Thomas C.
9Laeyendecker, Oliver
general
0Mary Ann Liebert, Inc
1Liebert
scope
0IQODW
1CGR
2CUY
3CVF
4ECM
5EIF
6NPM
7AAYXX
8CITATION
97U9
10H94
117X8
12BOBZL
13CLFQK
145PM
sort
creationdate20091001
titleGeographic HIV Type 1 Subtype Distribution in Rakai District, Uganda
authorCollinson-Streng, Aleisha N. ; Redd, Andrew D. ; Sewankambo, Nelson K. ; Serwadda, David ; Rezapour, Mona ; Lamers, Susanna L. ; Gray, Ronald H. ; Wawer, Maria J. ; Quinn, Thomas C. ; Laeyendecker, Oliver
facets
frbrtype5
frbrgroupidcdi_FETCH-LOGICAL-1696t-fcd1c2f156372f0059bd9bc1cafe8bde4fcecbaa9d8ff8023583366bba5a49ad3
rsrctypearticles
prefilterarticles
languageeng
creationdate2009
topic
0Adolescent
1Adult
2AIDS/HIV
3Animals
4Biological and medical sciences
5Biological diversity
6Distribution
7Female
8Fundamental and applied biological sciences. Psychology
9gag Gene Products, Human Immunodeficiency Virus - genetics
10Genetic aspects
11Genotype
12Geography
13HIV (Viruses)
14HIV Envelope Protein gp41 - genetics
15HIV infection
16HIV Infections - epidemiology
17HIV Infections - virology
18HIV-1 - classification
19HIV-1 - genetics
20HIV-1 - isolation & purification
21Human immunodeficiency virus 1
22Human viral diseases
23Humans
24Infectious diseases
25Male
26Medical sciences
27Microbiology
28Middle Aged
29Miscellaneous
30Molecular Sequence Data
31Retrovirus
32Rural Population
33Sequence Analysis, DNA
34Sequence Notes
35Uganda - epidemiology
36Viral diseases
37Virology
38Young Adult
toplevel
0peer_reviewed
1online_resources
creatorcontrib
0Collinson-Streng, Aleisha N.
1Redd, Andrew D.
2Sewankambo, Nelson K.
3Serwadda, David
4Rezapour, Mona
5Lamers, Susanna L.
6Gray, Ronald H.
7Wawer, Maria J.
8Quinn, Thomas C.
9Laeyendecker, Oliver
collection
0Pascal-Francis
1Medline
2MEDLINE
3MEDLINE (Ovid)
4MEDLINE
5MEDLINE
6PubMed
7CrossRef
8Virology and AIDS Abstracts
9AIDS and Cancer Research Abstracts
10MEDLINE - Academic
11OpenAIRE (Open Access)
12OpenAIRE
13PubMed Central (Full Participant titles)
jtitleAIDS research and human retroviruses
delivery
delcategoryRemote Search Resource
fulltextfulltext
addata
au
0Collinson-Streng, Aleisha N.
1Redd, Andrew D.
2Sewankambo, Nelson K.
3Serwadda, David
4Rezapour, Mona
5Lamers, Susanna L.
6Gray, Ronald H.
7Wawer, Maria J.
8Quinn, Thomas C.
9Laeyendecker, Oliver
formatjournal
genrearticle
ristypeJOUR
atitleGeographic HIV Type 1 Subtype Distribution in Rakai District, Uganda
jtitleAIDS research and human retroviruses
addtitleAIDS Res Hum Retroviruses
date2009-10-01
risdate2009
volume25
issue10
spage145
epage1048
pages145-1048
issn0889-2229
eissn1931-8405
codenARHRE7
abstractTo analyze HIV-1 subtype distribution, sequence analysis was performed on serum specimens obtained in 1994 from the Rakai Health Sciences community cohort in Uganda. Portions of gag -p24 and env -gp41 were sequenced and HIV subtype was determined for 773 subjects residing in 10 community clusters in rural Uganda. Subtypes A (17%) and D (70%) were the most common strains in the population. Subtype distribution varied by geographic region with significantly more subtype A in northern community clusters compared with southern clusters (21% vs. 8%, p  < 0.001) and more subtype D in southern clusters compared with northern clusters (78% vs. 65%, p  < 0.008). These data illustrate the geographic complexity of subtype variation, which has important implications for HIV-1 vaccine design.
copNew Rochelle, NY
pubMary Ann Liebert, Inc
pmid19803713
doi10.1089/aid.2009.0127
oafree_for_read