schliessen

Filtern

 

Bibliotheken

Serum magnesium and risk of sudden cardiac death in the Atherosclerosis Risk in Communities (ARIC) Study

Background We hypothesized that serum magnesium (Mg) is associated with increased risk of sudden cardiac death (SCD). Methods The Atherosclerosis Risk in Communities Study assessed risk factors and levels of serum Mg in a cohort of 45- to 64-year-old subjects in 1987-1989 (n = 14,232). After an aver... Full description

Journal Title: The American heart journal 2010, Vol.160 (3), p.464-470
Main Author: Peacock, James M., PhD
Other Authors: Ohira, Tetsuya, MD , Post, Wendy, MD , Sotoodehnia, Nona, MD , Rosamond, Wayne, PhD , Folsom, Aaron R., MD
Format: Electronic Article Electronic Article
Language: English
Subjects:
Quelle: Alma/SFX Local Collection
Publisher: New York, NY: Mosby, Inc
ID: ISSN: 0002-8703
Zum Text:
SendSend as email Add to Book BagAdd to Book Bag
Staff View
recordid: cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2939007
title: Serum magnesium and risk of sudden cardiac death in the Atherosclerosis Risk in Communities (ARIC) Study
format: Article
creator:
  • Peacock, James M., PhD
  • Ohira, Tetsuya, MD
  • Post, Wendy, MD
  • Sotoodehnia, Nona, MD
  • Rosamond, Wayne, PhD
  • Folsom, Aaron R., MD
subjects:
  • Abridged Index Medicus
  • Alcohol use
  • Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
  • Article
  • Atherosclerosis
  • Atherosclerosis (general aspects, experimental research)
  • Atherosclerosis - blood
  • Atherosclerosis - epidemiology
  • Biological and medical sciences
  • Blood and lymphatic vessels
  • Cardiac arrest
  • Cardiology. Vascular system
  • Cardiovascular
  • Cardiovascular disease
  • cohort study
  • Death, Sudden, Cardiac - epidemiology
  • Diabetes
  • Effect Modifier, Epidemiologic
  • Emergency and intensive care: neonates and children. Prematurity. Sudden death
  • Female
  • Glucose
  • Heart
  • Heart attacks
  • Heart rate
  • Humans
  • Hypertension
  • Intensive care medicine
  • Magnesium
  • Magnesium - blood
  • Male
  • Medical sciences
  • Middle Aged
  • Population
  • Proportional Hazards Models
  • Public health
  • Questionnaires
  • Risk Factors
  • Shipments
  • Smoking
  • Studies
  • sudden cardiac death
  • Triglycerides
  • Universities and colleges
ispartof: The American heart journal, 2010, Vol.160 (3), p.464-470
description: Background We hypothesized that serum magnesium (Mg) is associated with increased risk of sudden cardiac death (SCD). Methods The Atherosclerosis Risk in Communities Study assessed risk factors and levels of serum Mg in a cohort of 45- to 64-year-old subjects in 1987-1989 (n = 14,232). After an average of 12 years of follow-up, we observed 264 cases of SCD, as determined by physician review of all suspected cases. We used proportional hazards regression to evaluate the association of serum Mg with risk of SCD. Results Individuals in the highest quartile of serum Mg were at significantly lower risk of SCD in all models. This association persisted after adjustment for potential confounding variables, with an almost 40% reduced risk of SCD (hazard ratio 0.62, 95% CI 0.42-0.93) in quartile 4 versus 1 of serum Mg observed in the fully adjusted model. Conclusions This study suggests that low levels of serum Mg may be an important predictor of SCD. Further research into the effectiveness of Mg supplementation for those considered to be at high risk for SCD is warranted.
language: eng
source: Alma/SFX Local Collection
identifier: ISSN: 0002-8703
fulltext: fulltext
issn:
  • 0002-8703
  • 1097-6744
url: Link


@attributes
NO1
SEARCH_ENGINEprimo_central_multiple_fe
SEARCH_ENGINE_TYPEPrimo Central Search Engine
RANK2.559468
LOCALfalse
PrimoNMBib
record
control
sourceidgale_pubme
recordidTN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2939007
sourceformatXML
sourcesystemPC
galeidA236487175
sourcerecordidA236487175
originalsourceidFETCH-LOGICAL-1700t-f782ad625fc5d43a87d3213d5c79e811f2ef3e5a1e8bd2365b9032b2821024e93
addsrcrecordideNp9U2Fr1TAULaK4Of0BfpGCiPrhPW-StmkRBo-HusFA2PRzyEtu9_LWJlvSDvbvvd17bm7IKKRJc87pybk3WfaWwZwBq75s5nq9mXOgNVRzYPxZts-gkbNKFsXzbB8A-KyWIPayVyltaFnxunqZ7XGoecXLYj9bn2Ec-7zX5x6To5n2No8uXeShzdNoLfrc6GidNrlFPaxz5_NhjfmChhiS6abRpfx04tDeMvT96N3gMOWfFqfHy8_52TDam9fZi1Z3Cd_s3gfZ7-_ffi2PZic_fxwvFyczJgGGWStrri15a01pC6FraQVnwpZGNlgz1nJsBZaaYb2yXFTlqgHBV7zmDHiBjTjIDre6l-OqR2vQD1F36jK6XscbFbRTD3e8W6vzcK14IxoASQJHW4FwiV67iA-41uOgglW8kkoaYVaNIUN2xbURjFVM8IaVDROtkC1Jfdx5ieFqxDSo3iWDXac9hjEpWRbAZck4Id8_Qm7CGD0FpVgJRVVAIeAeda47VM63gU5gJk21oCyKWjJZEmr-HxQ9FntngsfW0fcHBLYlGCplitjenZiBmhpNbRQ1mpoaTUGl4Nbwu39jvmP87SwCfNgBdDK6a6P2xqV7nOAU962QfPRz4wY9uDBVx3VPWvi6ZSK107XDqJJx6A1aKpoZlA3uSfbhI7bpnHdk9QJvMN3HrxJXoM6muzRdJUaTEqgcfwCZ2BOr
sourcetypeOpen Access Repository
isCDItrue
recordtypearticle
pqid1504640430
display
typearticle
titleSerum magnesium and risk of sudden cardiac death in the Atherosclerosis Risk in Communities (ARIC) Study
sourceAlma/SFX Local Collection
creatorPeacock, James M., PhD ; Ohira, Tetsuya, MD ; Post, Wendy, MD ; Sotoodehnia, Nona, MD ; Rosamond, Wayne, PhD ; Folsom, Aaron R., MD
creatorcontribPeacock, James M., PhD ; Ohira, Tetsuya, MD ; Post, Wendy, MD ; Sotoodehnia, Nona, MD ; Rosamond, Wayne, PhD ; Folsom, Aaron R., MD
descriptionBackground We hypothesized that serum magnesium (Mg) is associated with increased risk of sudden cardiac death (SCD). Methods The Atherosclerosis Risk in Communities Study assessed risk factors and levels of serum Mg in a cohort of 45- to 64-year-old subjects in 1987-1989 (n = 14,232). After an average of 12 years of follow-up, we observed 264 cases of SCD, as determined by physician review of all suspected cases. We used proportional hazards regression to evaluate the association of serum Mg with risk of SCD. Results Individuals in the highest quartile of serum Mg were at significantly lower risk of SCD in all models. This association persisted after adjustment for potential confounding variables, with an almost 40% reduced risk of SCD (hazard ratio 0.62, 95% CI 0.42-0.93) in quartile 4 versus 1 of serum Mg observed in the fully adjusted model. Conclusions This study suggests that low levels of serum Mg may be an important predictor of SCD. Further research into the effectiveness of Mg supplementation for those considered to be at high risk for SCD is warranted.
identifier
0ISSN: 0002-8703
1EISSN: 1097-6744
2DOI: 10.1016/j.ahj.2010.06.012
3PMID: 20826254
4CODEN: AHJOA2
languageeng
publisherNew York, NY: Mosby, Inc
subjectAbridged Index Medicus ; Alcohol use ; Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy ; Article ; Atherosclerosis ; Atherosclerosis (general aspects, experimental research) ; Atherosclerosis - blood ; Atherosclerosis - epidemiology ; Biological and medical sciences ; Blood and lymphatic vessels ; Cardiac arrest ; Cardiology. Vascular system ; Cardiovascular ; Cardiovascular disease ; cohort study ; Death, Sudden, Cardiac - epidemiology ; Diabetes ; Effect Modifier, Epidemiologic ; Emergency and intensive care: neonates and children. Prematurity. Sudden death ; Female ; Glucose ; Heart ; Heart attacks ; Heart rate ; Humans ; Hypertension ; Intensive care medicine ; Magnesium ; Magnesium - blood ; Male ; Medical sciences ; Middle Aged ; Population ; Proportional Hazards Models ; Public health ; Questionnaires ; Risk Factors ; Shipments ; Smoking ; Studies ; sudden cardiac death ; Triglycerides ; Universities and colleges
ispartofThe American heart journal, 2010, Vol.160 (3), p.464-470
rights
0Mosby, Inc.
12010 Mosby, Inc.
22015 INIST-CNRS
32010 Mosby, Inc. All rights reserved.
4COPYRIGHT 2010 Elsevier B.V.
5Copyright Elsevier Limited Sep 2010
lds50peer_reviewed
oafree_for_read
citedbyFETCH-LOGICAL-1700t-f782ad625fc5d43a87d3213d5c79e811f2ef3e5a1e8bd2365b9032b2821024e93
links
openurl$$Topenurl_article
openurlfulltext$$Topenurlfull_article
thumbnail$$Usyndetics_thumb_exl
backlink
0$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=23239012$$DView record in Pascal Francis
1$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/20826254$$D View this record in MEDLINE/PubMed
search
creatorcontrib
0Peacock, James M., PhD
1Ohira, Tetsuya, MD
2Post, Wendy, MD
3Sotoodehnia, Nona, MD
4Rosamond, Wayne, PhD
5Folsom, Aaron R., MD
title
0Serum magnesium and risk of sudden cardiac death in the Atherosclerosis Risk in Communities (ARIC) Study
1The American heart journal
addtitleAm Heart J
descriptionBackground We hypothesized that serum magnesium (Mg) is associated with increased risk of sudden cardiac death (SCD). Methods The Atherosclerosis Risk in Communities Study assessed risk factors and levels of serum Mg in a cohort of 45- to 64-year-old subjects in 1987-1989 (n = 14,232). After an average of 12 years of follow-up, we observed 264 cases of SCD, as determined by physician review of all suspected cases. We used proportional hazards regression to evaluate the association of serum Mg with risk of SCD. Results Individuals in the highest quartile of serum Mg were at significantly lower risk of SCD in all models. This association persisted after adjustment for potential confounding variables, with an almost 40% reduced risk of SCD (hazard ratio 0.62, 95% CI 0.42-0.93) in quartile 4 versus 1 of serum Mg observed in the fully adjusted model. Conclusions This study suggests that low levels of serum Mg may be an important predictor of SCD. Further research into the effectiveness of Mg supplementation for those considered to be at high risk for SCD is warranted.
subject
0Abridged Index Medicus
1Alcohol use
2Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
3Article
4Atherosclerosis
5Atherosclerosis (general aspects, experimental research)
6Atherosclerosis - blood
7Atherosclerosis - epidemiology
8Biological and medical sciences
9Blood and lymphatic vessels
10Cardiac arrest
11Cardiology. Vascular system
12Cardiovascular
13Cardiovascular disease
14cohort study
15Death, Sudden, Cardiac - epidemiology
16Diabetes
17Effect Modifier, Epidemiologic
18Emergency and intensive care: neonates and children. Prematurity. Sudden death
19Female
20Glucose
21Heart
22Heart attacks
23Heart rate
24Humans
25Hypertension
26Intensive care medicine
27Magnesium
28Magnesium - blood
29Male
30Medical sciences
31Middle Aged
32Population
33Proportional Hazards Models
34Public health
35Questionnaires
36Risk Factors
37Shipments
38Smoking
39Studies
40sudden cardiac death
41Triglycerides
42Universities and colleges
issn
00002-8703
11097-6744
fulltexttrue
rsrctypearticle
creationdate2010
recordtypearticle
recordideNp9U2Fr1TAULaK4Of0BfpGCiPrhPW-StmkRBo-HusFA2PRzyEtu9_LWJlvSDvbvvd17bm7IKKRJc87pybk3WfaWwZwBq75s5nq9mXOgNVRzYPxZts-gkbNKFsXzbB8A-KyWIPayVyltaFnxunqZ7XGoecXLYj9bn2Ec-7zX5x6To5n2No8uXeShzdNoLfrc6GidNrlFPaxz5_NhjfmChhiS6abRpfx04tDeMvT96N3gMOWfFqfHy8_52TDam9fZi1Z3Cd_s3gfZ7-_ffi2PZic_fxwvFyczJgGGWStrri15a01pC6FraQVnwpZGNlgz1nJsBZaaYb2yXFTlqgHBV7zmDHiBjTjIDre6l-OqR2vQD1F36jK6XscbFbRTD3e8W6vzcK14IxoASQJHW4FwiV67iA-41uOgglW8kkoaYVaNIUN2xbURjFVM8IaVDROtkC1Jfdx5ieFqxDSo3iWDXac9hjEpWRbAZck4Id8_Qm7CGD0FpVgJRVVAIeAeda47VM63gU5gJk21oCyKWjJZEmr-HxQ9FntngsfW0fcHBLYlGCplitjenZiBmhpNbRQ1mpoaTUGl4Nbwu39jvmP87SwCfNgBdDK6a6P2xqV7nOAU962QfPRz4wY9uDBVx3VPWvi6ZSK107XDqJJx6A1aKpoZlA3uSfbhI7bpnHdk9QJvMN3HrxJXoM6muzRdJUaTEqgcfwCZ2BOr
startdate2010
enddate2010
creator
0Peacock, James M., PhD
1Ohira, Tetsuya, MD
2Post, Wendy, MD
3Sotoodehnia, Nona, MD
4Rosamond, Wayne, PhD
5Folsom, Aaron R., MD
general
0Mosby, Inc
1Mosby
2Elsevier B.V
3Elsevier Limited
scope
0IQODW
1CGR
2CUY
3CVF
4ECM
5EIF
6NPM
7AAYXX
8CITATION
9BSHEE
103V.
117QO
127RV
137TS
147X7
157XB
1688C
1788E
188AO
198C1
208FD
218FI
228FJ
238FK
248G5
25ABUWG
26AN0
27AZQEC
28BENPR
29DWQXO
30FR3
31FYUFA
32GHDGH
33GNUQQ
34GUQSH
35K9.
36KB0
37M0S
38M0T
39M1P
40M2O
41MBDVC
42NAPCQ
43P64
44PADUT
45PQEST
46PQQKQ
47PQUKI
48PRINS
49Q9U
507X8
51BOBZL
52CLFQK
535PM
sort
creationdate2010
titleSerum magnesium and risk of sudden cardiac death in the Atherosclerosis Risk in Communities (ARIC) Study
authorPeacock, James M., PhD ; Ohira, Tetsuya, MD ; Post, Wendy, MD ; Sotoodehnia, Nona, MD ; Rosamond, Wayne, PhD ; Folsom, Aaron R., MD
facets
frbrtype5
frbrgroupidcdi_FETCH-LOGICAL-1700t-f782ad625fc5d43a87d3213d5c79e811f2ef3e5a1e8bd2365b9032b2821024e93
rsrctypearticles
prefilterarticles
languageeng
creationdate2010
topic
0Abridged Index Medicus
1Alcohol use
2Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
3Article
4Atherosclerosis
5Atherosclerosis (general aspects, experimental research)
6Atherosclerosis - blood
7Atherosclerosis - epidemiology
8Biological and medical sciences
9Blood and lymphatic vessels
10Cardiac arrest
11Cardiology. Vascular system
12Cardiovascular
13Cardiovascular disease
14cohort study
15Death, Sudden, Cardiac - epidemiology
16Diabetes
17Effect Modifier, Epidemiologic
18Emergency and intensive care: neonates and children. Prematurity. Sudden death
19Female
20Glucose
21Heart
22Heart attacks
23Heart rate
24Humans
25Hypertension
26Intensive care medicine
27Magnesium
28Magnesium - blood
29Male
30Medical sciences
31Middle Aged
32Population
33Proportional Hazards Models
34Public health
35Questionnaires
36Risk Factors
37Shipments
38Smoking
39Studies
40sudden cardiac death
41Triglycerides
42Universities and colleges
toplevel
0peer_reviewed
1online_resources
creatorcontrib
0Peacock, James M., PhD
1Ohira, Tetsuya, MD
2Post, Wendy, MD
3Sotoodehnia, Nona, MD
4Rosamond, Wayne, PhD
5Folsom, Aaron R., MD
collection
0Pascal-Francis
1Medline
2MEDLINE
3MEDLINE (Ovid)
4MEDLINE
5MEDLINE
6PubMed
7CrossRef
8Academic OneFile (A&I only)
9ProQuest Central (Corporate)
10Biotechnology Research Abstracts
11Nursing & Allied Health Database
12Physical Education Index
13Health & Medical Collection
14ProQuest Central (purchase pre-March 2016)
15Healthcare Administration Database (Alumni)
16Medical Database (Alumni Edition)
17ProQuest Pharma Collection
18Public Health Database
19Technology Research Database
20Hospital Premium Collection
21Hospital Premium Collection (Alumni Edition)
22ProQuest Central (Alumni) (purchase pre-March 2016)
23Research Library (Alumni Edition)
24ProQuest Central (Alumni Edition)
25British Nursing Database
26ProQuest Central Essentials
27ProQuest Central
28ProQuest Central Korea
29Engineering Research Database
30Health Research Premium Collection
31Health Research Premium Collection (Alumni)
32ProQuest Central Student
33Research Library Prep
34ProQuest Health & Medical Complete (Alumni)
35Nursing & Allied Health Database (Alumni Edition)
36Health & Medical Collection (Alumni Edition)
37Healthcare Administration Database
38Medical Database
39Research Library
40Research Library (Corporate)
41Nursing & Allied Health Premium
42Biotechnology and BioEngineering Abstracts
43Research Library China
44ProQuest One Academic Eastern Edition
45ProQuest One Academic
46ProQuest One Academic UKI Edition
47ProQuest Central China
48ProQuest Central Basic
49MEDLINE - Academic
50OpenAIRE (Open Access)
51OpenAIRE
52PubMed Central (Full Participant titles)
jtitleThe American heart journal
delivery
delcategoryRemote Search Resource
fulltextfulltext
addata
au
0Peacock, James M., PhD
1Ohira, Tetsuya, MD
2Post, Wendy, MD
3Sotoodehnia, Nona, MD
4Rosamond, Wayne, PhD
5Folsom, Aaron R., MD
formatjournal
genrearticle
ristypeJOUR
atitleSerum magnesium and risk of sudden cardiac death in the Atherosclerosis Risk in Communities (ARIC) Study
jtitleThe American heart journal
addtitleAm Heart J
date2010
risdate2010
volume160
issue3
spage464
epage470
pages464-470
issn0002-8703
eissn1097-6744
codenAHJOA2
abstractBackground We hypothesized that serum magnesium (Mg) is associated with increased risk of sudden cardiac death (SCD). Methods The Atherosclerosis Risk in Communities Study assessed risk factors and levels of serum Mg in a cohort of 45- to 64-year-old subjects in 1987-1989 (n = 14,232). After an average of 12 years of follow-up, we observed 264 cases of SCD, as determined by physician review of all suspected cases. We used proportional hazards regression to evaluate the association of serum Mg with risk of SCD. Results Individuals in the highest quartile of serum Mg were at significantly lower risk of SCD in all models. This association persisted after adjustment for potential confounding variables, with an almost 40% reduced risk of SCD (hazard ratio 0.62, 95% CI 0.42-0.93) in quartile 4 versus 1 of serum Mg observed in the fully adjusted model. Conclusions This study suggests that low levels of serum Mg may be an important predictor of SCD. Further research into the effectiveness of Mg supplementation for those considered to be at high risk for SCD is warranted.
copNew York, NY
pubMosby, Inc
pmid20826254
doi10.1016/j.ahj.2010.06.012
oafree_for_read