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Polysaccharides from Medicinal Herbs As Potential Therapeutics for Aging and Age-Related Neurodegeneration

Recent studies have uncovered important aging clues, including free radicals, inflammation, telomeres, and life span pathways. Strategies to regulate aging-associated signaling pathways are expected to be effective in the delay and prevention of age-related disorders. For example, herbal polysacchar... Full description

Journal Title: Rejuvenation research 2014, Vol.17 (2), p.21-204
Main Author: Li, Haifeng
Other Authors: Ma, Fangli , Hu, Minghua , Ma, Chung Wah , Xiao, Lingyun , Zhang, Ju , Xiang, Yanxia , Huang, Zebo
Format: Electronic Article Electronic Article
Language: English
Subjects:
Quelle: Alma/SFX Local Collection
Publisher: United States: Mary Ann Liebert, Inc
ID: ISSN: 1549-1684
Link: https://www.ncbi.nlm.nih.gov/pubmed/24125569
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title: Polysaccharides from Medicinal Herbs As Potential Therapeutics for Aging and Age-Related Neurodegeneration
format: Article
creator:
  • Li, Haifeng
  • Ma, Fangli
  • Hu, Minghua
  • Ma, Chung Wah
  • Xiao, Lingyun
  • Zhang, Ju
  • Xiang, Yanxia
  • Huang, Zebo
subjects:
  • Aging - drug effects
  • Aging - pathology
  • Humans
  • Nerve Degeneration - drug therapy
  • Neurodegenerative Diseases - drug therapy
  • Original
  • Original Articles
  • Plants, Medicinal - chemistry
  • Polysaccharides - pharmacology
  • Polysaccharides - therapeutic use
ispartof: Rejuvenation research, 2014, Vol.17 (2), p.21-204
description: Recent studies have uncovered important aging clues, including free radicals, inflammation, telomeres, and life span pathways. Strategies to regulate aging-associated signaling pathways are expected to be effective in the delay and prevention of age-related disorders. For example, herbal polysaccharides with considerable anti-oxidant and anti-inflammation capacities have been shown to be beneficial in aging and age-related neurodegenerative diseases. Polysaccharides capable of reducing cellular senescence and modulating life span via telomere and insulin pathways have also been found to have the potential to inhibit protein aggregation and aggregation-associated neurodegeneration. Here we present the current status of polysaccharides in anti-aging and anti-neurodegenerative studies.
language: eng
source: Alma/SFX Local Collection
identifier: ISSN: 1549-1684
fulltext: fulltext
issn:
  • 1549-1684
  • 1557-8577
url: Link


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descriptionRecent studies have uncovered important aging clues, including free radicals, inflammation, telomeres, and life span pathways. Strategies to regulate aging-associated signaling pathways are expected to be effective in the delay and prevention of age-related disorders. For example, herbal polysaccharides with considerable anti-oxidant and anti-inflammation capacities have been shown to be beneficial in aging and age-related neurodegenerative diseases. Polysaccharides capable of reducing cellular senescence and modulating life span via telomere and insulin pathways have also been found to have the potential to inhibit protein aggregation and aggregation-associated neurodegeneration. Here we present the current status of polysaccharides in anti-aging and anti-neurodegenerative studies.
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subjectAging - drug effects ; Aging - pathology ; Humans ; Nerve Degeneration - drug therapy ; Neurodegenerative Diseases - drug therapy ; Original ; Original Articles ; Plants, Medicinal - chemistry ; Polysaccharides - pharmacology ; Polysaccharides - therapeutic use
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descriptionRecent studies have uncovered important aging clues, including free radicals, inflammation, telomeres, and life span pathways. Strategies to regulate aging-associated signaling pathways are expected to be effective in the delay and prevention of age-related disorders. For example, herbal polysaccharides with considerable anti-oxidant and anti-inflammation capacities have been shown to be beneficial in aging and age-related neurodegenerative diseases. Polysaccharides capable of reducing cellular senescence and modulating life span via telomere and insulin pathways have also been found to have the potential to inhibit protein aggregation and aggregation-associated neurodegeneration. Here we present the current status of polysaccharides in anti-aging and anti-neurodegenerative studies.
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abstractRecent studies have uncovered important aging clues, including free radicals, inflammation, telomeres, and life span pathways. Strategies to regulate aging-associated signaling pathways are expected to be effective in the delay and prevention of age-related disorders. For example, herbal polysaccharides with considerable anti-oxidant and anti-inflammation capacities have been shown to be beneficial in aging and age-related neurodegenerative diseases. Polysaccharides capable of reducing cellular senescence and modulating life span via telomere and insulin pathways have also been found to have the potential to inhibit protein aggregation and aggregation-associated neurodegeneration. Here we present the current status of polysaccharides in anti-aging and anti-neurodegenerative studies.
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