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Caenorhabditis elegans in Chinese Medicinal Studies: Making the Case for Aging and Neurodegeneration

Aging is a progressive process with degenerative changes of various tissues and organs. As a classic model organism in genetics and neurobiology, Caenorhabditis elegans is also a powerful system in aging and behavioral studies and can be used at both the molecular and organismal levels to evaluate p... Full description

Journal Title: Rejuvenation research 2014-04-01, Vol.17 (2), p.25-208
Main Author: Wang, Qiangqiang
Other Authors: Yang, Fan , Guo, Wei , Zhang, Ju , Xiao, Lingyun , Li, Haifeng , Jia, Weizhang , Huang, Zebo
Format: Electronic Article Electronic Article
Language: English
Subjects:
Aging - physiology
Animals
Caenorhabditis elegans - physiology
Longevity
Medicine, Chinese Traditional
Nerve Degeneration - drug therapy
Original
Original Articles
Oxidative Stress
Quelle: Alma/SFX Local Collection
Publisher: United States: Mary Ann Liebert, Inc
ID: ISSN: 1549-1684
Link: https://www.ncbi.nlm.nih.gov/pubmed/24125529
Zum Text:
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title: Caenorhabditis elegans in Chinese Medicinal Studies: Making the Case for Aging and Neurodegeneration
format: Article
creator:
  • Wang, Qiangqiang
  • Yang, Fan
  • Guo, Wei
  • Zhang, Ju
  • Xiao, Lingyun
  • Li, Haifeng
  • Jia, Weizhang
  • Huang, Zebo
subjects:
  • Aging - physiology
  • Animals
  • Caenorhabditis elegans - physiology
  • Longevity
  • Medicine, Chinese Traditional
  • Nerve Degeneration - drug therapy
  • Original
  • Original Articles
  • Oxidative Stress
ispartof: Rejuvenation research, 2014-04-01, Vol.17 (2), p.25-208
description: Aging is a progressive process with degenerative changes of various tissues and organs. As a classic model organism in genetics and neurobiology, Caenorhabditis elegans is also a powerful system in aging and behavioral studies and can be used at both the molecular and organismal levels to evaluate potential therapeutics for age-related neurodegeneration, owing to its short life span, relative simplicity, and high degree of experimental tractability as well as significant conservation of disease genes and signaling pathways with humans. We attempt here to summarize the use of C. elegans models in exploring traditional Chinese medicine for potential remedies against aging and neurodegeneration.
language: eng
source: Alma/SFX Local Collection
identifier: ISSN: 1549-1684
fulltext: fulltext
issn:
  • 1549-1684
  • 1557-8577
url: Link


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descriptionAging is a progressive process with degenerative changes of various tissues and organs. As a classic model organism in genetics and neurobiology, Caenorhabditis elegans is also a powerful system in aging and behavioral studies and can be used at both the molecular and organismal levels to evaluate potential therapeutics for age-related neurodegeneration, owing to its short life span, relative simplicity, and high degree of experimental tractability as well as significant conservation of disease genes and signaling pathways with humans. We attempt here to summarize the use of C. elegans models in exploring traditional Chinese medicine for potential remedies against aging and neurodegeneration.
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subjectAging - physiology ; Animals ; Caenorhabditis elegans - physiology ; Longevity ; Medicine, Chinese Traditional ; Nerve Degeneration - drug therapy ; Original ; Original Articles ; Oxidative Stress
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abstractAging is a progressive process with degenerative changes of various tissues and organs. As a classic model organism in genetics and neurobiology, Caenorhabditis elegans is also a powerful system in aging and behavioral studies and can be used at both the molecular and organismal levels to evaluate potential therapeutics for age-related neurodegeneration, owing to its short life span, relative simplicity, and high degree of experimental tractability as well as significant conservation of disease genes and signaling pathways with humans. We attempt here to summarize the use of C. elegans models in exploring traditional Chinese medicine for potential remedies against aging and neurodegeneration.
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doi10.1089/rej.2013.1512
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