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Opening snap and isovolumic relaxation period in relation to mitral valve flow in patients with mitral stenosis. Significance of A2--OS interval

In 15 patients with pure or predominant mitral stenosis and in a control group of 11 patients without mitral stenosis the blood flow velocity through the mitral valve orifice was recorded by means of a directional Doppler ultrasound velocity catheter introduced transeptally and positioned in the ori... Full description

Journal Title: British Heart Journal 1976-02, Vol.38 (2), p.135-146
Main Author: Kalmanson, D
Other Authors: Veyrat, C , Bernier, A , Witchitz, S , Chiche, P
Format: Electronic Article Electronic Article
Language: English
Subjects:
Quelle: Alma/SFX Local Collection
Publisher: England: BMJ Publishing Group Ltd and British Cardiovascular Society
ID: ISSN: 0007-0769
Link: https://www.ncbi.nlm.nih.gov/pubmed/1259828
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title: Opening snap and isovolumic relaxation period in relation to mitral valve flow in patients with mitral stenosis. Significance of A2--OS interval
format: Article
creator:
  • Kalmanson, D
  • Veyrat, C
  • Bernier, A
  • Witchitz, S
  • Chiche, P
subjects:
  • Abridged Index Medicus
  • Adult
  • Atrial Fibrillation - complications
  • Blood Flow Velocity
  • Blood Pressure
  • Calcinosis - complications
  • cardiovascular diseases
  • cardiovascular system
  • Female
  • Heart Auscultation
  • Heart Sounds
  • Humans
  • Male
  • Middle Aged
  • Mitral Valve - physiopathology
  • Mitral Valve Stenosis - complications
  • Mitral Valve Stenosis - physiopathology
  • Phonocardiography
  • Research Article
  • Statistics as Topic
  • Time Factors
ispartof: British Heart Journal, 1976-02, Vol.38 (2), p.135-146
description: In 15 patients with pure or predominant mitral stenosis and in a control group of 11 patients without mitral stenosis the blood flow velocity through the mitral valve orifice was recorded by means of a directional Doppler ultrasound velocity catheter introduced transeptally and positioned in the orifice of the mitral valve. A simultaneous surface phonocardiogram was obtained. The timing of the mitral opening snap in relation to the blood velocity record of the flow through the valve supported the hypothesis that the opening snap is due to a sudden tensing of the valve leaflets by the chordae tendineae. Determination of the exact time of mitral valve opening, made possible by the blood velocity record, led to the division of the classical A2-0S interval (aortic valve closure to opening snap) into two components representing respectively the diastolic isovolumic relaxation period and the time of excursion of the mitral valve cusps. The durations of the isovolumic relaxation period were compared with those in the control patients and were found to correlate with the severity of the mitral stenosis, whereas those of the excursion time of the mitral cusps were influenced by the presence or absence of mitral valve calcification.
language: eng
source: Alma/SFX Local Collection
identifier: ISSN: 0007-0769
fulltext: fulltext
issn:
  • 0007-0769
  • 1355-6037
  • 1468-201X
  • 2053-5864
url: Link


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titleOpening snap and isovolumic relaxation period in relation to mitral valve flow in patients with mitral stenosis. Significance of A2--OS interval
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descriptionIn 15 patients with pure or predominant mitral stenosis and in a control group of 11 patients without mitral stenosis the blood flow velocity through the mitral valve orifice was recorded by means of a directional Doppler ultrasound velocity catheter introduced transeptally and positioned in the orifice of the mitral valve. A simultaneous surface phonocardiogram was obtained. The timing of the mitral opening snap in relation to the blood velocity record of the flow through the valve supported the hypothesis that the opening snap is due to a sudden tensing of the valve leaflets by the chordae tendineae. Determination of the exact time of mitral valve opening, made possible by the blood velocity record, led to the division of the classical A2-0S interval (aortic valve closure to opening snap) into two components representing respectively the diastolic isovolumic relaxation period and the time of excursion of the mitral valve cusps. The durations of the isovolumic relaxation period were compared with those in the control patients and were found to correlate with the severity of the mitral stenosis, whereas those of the excursion time of the mitral cusps were influenced by the presence or absence of mitral valve calcification.
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subjectAbridged Index Medicus ; Adult ; Atrial Fibrillation - complications ; Blood Flow Velocity ; Blood Pressure ; Calcinosis - complications ; cardiovascular diseases ; cardiovascular system ; Female ; Heart Auscultation ; Heart Sounds ; Humans ; Male ; Middle Aged ; Mitral Valve - physiopathology ; Mitral Valve Stenosis - complications ; Mitral Valve Stenosis - physiopathology ; Phonocardiography ; Research Article ; Statistics as Topic ; Time Factors
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abstractIn 15 patients with pure or predominant mitral stenosis and in a control group of 11 patients without mitral stenosis the blood flow velocity through the mitral valve orifice was recorded by means of a directional Doppler ultrasound velocity catheter introduced transeptally and positioned in the orifice of the mitral valve. A simultaneous surface phonocardiogram was obtained. The timing of the mitral opening snap in relation to the blood velocity record of the flow through the valve supported the hypothesis that the opening snap is due to a sudden tensing of the valve leaflets by the chordae tendineae. Determination of the exact time of mitral valve opening, made possible by the blood velocity record, led to the division of the classical A2-0S interval (aortic valve closure to opening snap) into two components representing respectively the diastolic isovolumic relaxation period and the time of excursion of the mitral valve cusps. The durations of the isovolumic relaxation period were compared with those in the control patients and were found to correlate with the severity of the mitral stenosis, whereas those of the excursion time of the mitral cusps were influenced by the presence or absence of mitral valve calcification.
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