schliessen

Filtern

 

Bibliotheken

Hormone replacement therapy, body mass index and asthma in perimenopausal women: a cross sectional survey

Background: Hormone replacement therapy (HRT) and obesity both appear to increase the risk of asthma. A study was undertaken to investigate the association of HRT with asthma and hay fever in a population of perimenopausal women, focusing on a possible interaction with body mass index (BMI). Methods... Full description

Journal Title: Thorax 2006-01, Vol.61 (1), p.34-40
Main Author: Gómez Real, F
Other Authors: Svanes, C , Björnsson, E H , Franklin, K , Gislason, D , Gislason, T , Gulsvik, A , Janson, C , Jögi, R , Kiserud, T , Norbäck, D , Nyström, L , Torén, K , Wentzel-Larsen, T , Omenaas, E
Format: Electronic Article Electronic Article
Language: English
Subjects:
BMI
HRT
Quelle: Alma/SFX Local Collection
Publisher: London: BMJ Publishing Group Ltd and British Thoracic Society
ID: ISSN: 0040-6376
Zum Text:
SendSend as email Add to Book BagAdd to Book Bag
Staff View
recordid: cdi_swepub_primary_oai_DiVA_org_uu_18205
title: Hormone replacement therapy, body mass index and asthma in perimenopausal women: a cross sectional survey
format: Article
creator:
  • Gómez Real, F
  • Svanes, C
  • Björnsson, E H
  • Franklin, K
  • Gislason, D
  • Gislason, T
  • Gulsvik, A
  • Janson, C
  • Jögi, R
  • Kiserud, T
  • Norbäck, D
  • Nyström, L
  • Torén, K
  • Wentzel-Larsen, T
  • Omenaas, E
subjects:
  • Adult
  • Asthma
  • Asthma - chemically induced
  • Asthma - etiology
  • Asthma/chemically induced/etiology
  • Biological and medical sciences
  • BMI
  • Body Mass Index
  • Care and treatment
  • Chronic obstructive pulmonary disease, asthma
  • Complications and side effects
  • Cross-Sectional Studies
  • Development and progression
  • ECRHS
  • European Community Respiratory Health Survey
  • Female
  • hormone replacement therapy
  • Hormone Replacement Therapy - adverse effects
  • Hormone therapy
  • HRT
  • Humans
  • insulin resistance
  • Medical sciences
  • Menopause
  • Middle Aged
  • Perimenopause
  • Pneumology
  • Questionnaires
  • Respiratory Health in Northern Europe
  • RHINE
  • Rhinitis, Allergic, Seasonal - etiology
  • Smoking - adverse effects
  • Surveys and Questionnaires
ispartof: Thorax, 2006-01, Vol.61 (1), p.34-40
description: Background: Hormone replacement therapy (HRT) and obesity both appear to increase the risk of asthma. A study was undertaken to investigate the association of HRT with asthma and hay fever in a population of perimenopausal women, focusing on a possible interaction with body mass index (BMI). Methods: A postal questionnaire was sent to population based samples in Denmark, Estonia, Iceland, Norway, and Sweden in 1999–2001, and 8588 women aged 25–54 years responded (77%). Pregnant women, women using oral contraceptives, and women
language: eng
source: Alma/SFX Local Collection
identifier: ISSN: 0040-6376
fulltext: fulltext
issn:
  • 0040-6376
  • 1468-3296
url: Link


@attributes
NO1
SEARCH_ENGINEprimo_central_multiple_fe
SEARCH_ENGINE_TYPEPrimo Central Search Engine
RANK2.3602626
LOCALfalse
PrimoNMBib
record
control
sourceidgale_swepu
recordidTN_cdi_swepub_primary_oai_DiVA_org_uu_18205
sourceformatXML
sourcesystemPC
galeidA141599934
sourcerecordidA141599934
originalsourceidFETCH-LOGICAL-1764t-79ff941077dc23e92bb96ea0ac6bcb76a61eea63f46ef15090348fac2198efc73
addsrcrecordideNqNks1v1DAQxSMEoqVw5oYiIThAd-uPxHY4IFUFWqRSJD5abpbjTLpeknixk7b73zNLVi1bIUA5RBn_3svM-CXJY0qmlHKx18-upoyQfEoyohS9k2zTTKgJZ4W4m2wTrE4El2IreRDjnBCiKJX3ky0qWJaRgm8n7siH1neQBlg0xkILXZ_2MwhmsdxNS18t09bEmLqugqvUdFVqYj9rDRbSBQSHvF-YIZomvfT48So1qQ0eFRFs73yHB3EIF7B8mNyrTRPh0fq9k3x99_bLwdHk-OPh-4P94wmVIusnsqjrIqNEysoyDgUry0KAIcaK0pZSGEEBjOB1JqCmOSkIz1RtLKOFgtpKvpO8HH3jJSyGUi-wSROW2hun37jTfe3DuR4GTRUjOdK7_0G3iGe4b8RfjziyLVQWtxVMs6HaPOncTJ_7C82IIpKsDI5GA7-AzrgAG9qqg177SjMhtalKUgGXeH25qnLGKTMkk8AU53WtFFo9X_cS_I8BYq9bFy00jenAD1HTIi-EkqsZn94C534IeDPISIVrZ5TwG-rcNKBdV3scwK4s9T4OnxdFwTOkpn-g8KmgdRaDVDusbwj2RsGvVASorwemRK8yrDHDepVhPWYYFU9-3_ENvw4tAs_WgInWNHUwnXXxhpMZYVwR5PJbv7auN6tQYs-u-UsDk1HnYg9X174mfNcCryPXJ6cH-jM7-fTh7PCbPkP-xciX7fyf0_0Eycknqw
sourcetypeOpen Access Repository
isCDItrue
recordtypearticle
pqid1781762103
display
typearticle
titleHormone replacement therapy, body mass index and asthma in perimenopausal women: a cross sectional survey
sourceAlma/SFX Local Collection
creatorGómez Real, F ; Svanes, C ; Björnsson, E H ; Franklin, K ; Gislason, D ; Gislason, T ; Gulsvik, A ; Janson, C ; Jögi, R ; Kiserud, T ; Norbäck, D ; Nyström, L ; Torén, K ; Wentzel-Larsen, T ; Omenaas, E
creatorcontribGómez Real, F ; Svanes, C ; Björnsson, E H ; Franklin, K ; Gislason, D ; Gislason, T ; Gulsvik, A ; Janson, C ; Jögi, R ; Kiserud, T ; Norbäck, D ; Nyström, L ; Torén, K ; Wentzel-Larsen, T ; Omenaas, E
descriptionBackground: Hormone replacement therapy (HRT) and obesity both appear to increase the risk of asthma. A study was undertaken to investigate the association of HRT with asthma and hay fever in a population of perimenopausal women, focusing on a possible interaction with body mass index (BMI). Methods: A postal questionnaire was sent to population based samples in Denmark, Estonia, Iceland, Norway, and Sweden in 1999–2001, and 8588 women aged 25–54 years responded (77%). Pregnant women, women using oral contraceptives, and women <46 years were excluded. Analyses included 2206 women aged 46–54 years of which 884 were menopausal and 540 used HRT. Stratified analyses by BMI in tertiles were performed. Results: HRT was associated with an increased risk for asthma (OR 1.57 (95% CI 1.07 to 2.30)), wheeze (OR 1.60 (95% CI 1.22 to 2.10)), and hay fever (OR 1.48 (95% CI 1.15 to 1.90)). The associations with asthma and wheeze were significantly stronger among women with BMI in the lower tertile (asthma OR 2.41 (95% CI 1.21 to 4.77); wheeze OR 2.04 (95% CI 1.23 to 3.36)) than in heavier women (asthma: pinteraction = 0.030; wheeze: pinteraction = 0.042). Increasing BMI was associated with more asthma (OR 1.08 (95% CI 1.05 to 1.12) per kg/m2). This effect was only found in women not taking HRT (OR 1.10 (95% CI 1.05 to 1.14) per kg/m2); no such association was detected in HRT users (OR 1.00 (95% CI 0.92 to 1.08) per kg/m2) (pinteraction = 0.046). Menopause was not significantly associated with asthma, wheeze, or hay fever. Conclusions: In perimenopausal women there is an interaction between HRT and BMI in the effects on asthma. Lean women who were HRT users had as high a risk for asthma as overweight women not taking HRT. It is suggested that HRT and overweight increase the risk of asthma through partly common pathways.
identifier
0ISSN: 0040-6376
1EISSN: 1468-3296
2DOI: 10.1136/thx.2005.040881
3PMID: 16244093
4CODEN: THORA7
languageeng
publisherLondon: BMJ Publishing Group Ltd and British Thoracic Society
subjectAdult ; Asthma ; Asthma - chemically induced ; Asthma - etiology ; Asthma/chemically induced/etiology ; Biological and medical sciences ; BMI ; Body Mass Index ; Care and treatment ; Chronic obstructive pulmonary disease, asthma ; Complications and side effects ; Cross-Sectional Studies ; Development and progression ; ECRHS ; European Community Respiratory Health Survey ; Female ; hormone replacement therapy ; Hormone Replacement Therapy - adverse effects ; Hormone therapy ; HRT ; Humans ; insulin resistance ; Medical sciences ; Menopause ; Middle Aged ; Perimenopause ; Pneumology ; Questionnaires ; Respiratory Health in Northern Europe ; RHINE ; Rhinitis, Allergic, Seasonal - etiology ; Smoking - adverse effects ; Surveys and Questionnaires
ispartofThorax, 2006-01, Vol.61 (1), p.34-40
rights
0Copyright 2006 Thorax
12006 INIST-CNRS
2Copyright: 2006 Copyright 2006 Thorax
3Copyright © 2006 BMJ Publishing Group and British Thoracic Society
lds50peer_reviewed
oafree_for_read
citedbyFETCH-LOGICAL-1764t-79ff941077dc23e92bb96ea0ac6bcb76a61eea63f46ef15090348fac2198efc73
links
openurl$$Topenurl_article
openurlfulltext$$Topenurlfull_article
thumbnail$$Usyndetics_thumb_exl
backlink
0$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=17402380$$DView record in Pascal Francis
1$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16244093$$D View this record in MEDLINE/PubMed
2$$Uhttp://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-14136$$DView record from Swedish Publication Index
3$$Uhttp://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-18205$$DView record from Swedish Publication Index
search
creatorcontrib
0Gómez Real, F
1Svanes, C
2Björnsson, E H
3Franklin, K
4Gislason, D
5Gislason, T
6Gulsvik, A
7Janson, C
8Jögi, R
9Kiserud, T
10Norbäck, D
11Nyström, L
12Torén, K
13Wentzel-Larsen, T
14Omenaas, E
title
0Hormone replacement therapy, body mass index and asthma in perimenopausal women: a cross sectional survey
1Thorax
addtitleThorax
descriptionBackground: Hormone replacement therapy (HRT) and obesity both appear to increase the risk of asthma. A study was undertaken to investigate the association of HRT with asthma and hay fever in a population of perimenopausal women, focusing on a possible interaction with body mass index (BMI). Methods: A postal questionnaire was sent to population based samples in Denmark, Estonia, Iceland, Norway, and Sweden in 1999–2001, and 8588 women aged 25–54 years responded (77%). Pregnant women, women using oral contraceptives, and women <46 years were excluded. Analyses included 2206 women aged 46–54 years of which 884 were menopausal and 540 used HRT. Stratified analyses by BMI in tertiles were performed. Results: HRT was associated with an increased risk for asthma (OR 1.57 (95% CI 1.07 to 2.30)), wheeze (OR 1.60 (95% CI 1.22 to 2.10)), and hay fever (OR 1.48 (95% CI 1.15 to 1.90)). The associations with asthma and wheeze were significantly stronger among women with BMI in the lower tertile (asthma OR 2.41 (95% CI 1.21 to 4.77); wheeze OR 2.04 (95% CI 1.23 to 3.36)) than in heavier women (asthma: pinteraction = 0.030; wheeze: pinteraction = 0.042). Increasing BMI was associated with more asthma (OR 1.08 (95% CI 1.05 to 1.12) per kg/m2). This effect was only found in women not taking HRT (OR 1.10 (95% CI 1.05 to 1.14) per kg/m2); no such association was detected in HRT users (OR 1.00 (95% CI 0.92 to 1.08) per kg/m2) (pinteraction = 0.046). Menopause was not significantly associated with asthma, wheeze, or hay fever. Conclusions: In perimenopausal women there is an interaction between HRT and BMI in the effects on asthma. Lean women who were HRT users had as high a risk for asthma as overweight women not taking HRT. It is suggested that HRT and overweight increase the risk of asthma through partly common pathways.
subject
0Adult
1Asthma
2Asthma - chemically induced
3Asthma - etiology
4Asthma/chemically induced/etiology
5Biological and medical sciences
6BMI
7Body Mass Index
8Care and treatment
9Chronic obstructive pulmonary disease, asthma
10Complications and side effects
11Cross-Sectional Studies
12Development and progression
13ECRHS
14European Community Respiratory Health Survey
15Female
16hormone replacement therapy
17Hormone Replacement Therapy - adverse effects
18Hormone therapy
19HRT
20Humans
21insulin resistance
22Medical sciences
23Menopause
24Middle Aged
25Perimenopause
26Pneumology
27Questionnaires
28Respiratory Health in Northern Europe
29RHINE
30Rhinitis, Allergic, Seasonal - etiology
31Smoking - adverse effects
32Surveys and Questionnaires
issn
00040-6376
11468-3296
fulltexttrue
rsrctypearticle
creationdate2006
recordtypearticle
recordideNqNks1v1DAQxSMEoqVw5oYiIThAd-uPxHY4IFUFWqRSJD5abpbjTLpeknixk7b73zNLVi1bIUA5RBn_3svM-CXJY0qmlHKx18-upoyQfEoyohS9k2zTTKgJZ4W4m2wTrE4El2IreRDjnBCiKJX3ky0qWJaRgm8n7siH1neQBlg0xkILXZ_2MwhmsdxNS18t09bEmLqugqvUdFVqYj9rDRbSBQSHvF-YIZomvfT48So1qQ0eFRFs73yHB3EIF7B8mNyrTRPh0fq9k3x99_bLwdHk-OPh-4P94wmVIusnsqjrIqNEysoyDgUry0KAIcaK0pZSGEEBjOB1JqCmOSkIz1RtLKOFgtpKvpO8HH3jJSyGUi-wSROW2hun37jTfe3DuR4GTRUjOdK7_0G3iGe4b8RfjziyLVQWtxVMs6HaPOncTJ_7C82IIpKsDI5GA7-AzrgAG9qqg177SjMhtalKUgGXeH25qnLGKTMkk8AU53WtFFo9X_cS_I8BYq9bFy00jenAD1HTIi-EkqsZn94C534IeDPISIVrZ5TwG-rcNKBdV3scwK4s9T4OnxdFwTOkpn-g8KmgdRaDVDusbwj2RsGvVASorwemRK8yrDHDepVhPWYYFU9-3_ENvw4tAs_WgInWNHUwnXXxhpMZYVwR5PJbv7auN6tQYs-u-UsDk1HnYg9X174mfNcCryPXJ6cH-jM7-fTh7PCbPkP-xciX7fyf0_0Eycknqw
startdate200601
enddate200601
creator
0Gómez Real, F
1Svanes, C
2Björnsson, E H
3Franklin, K
4Gislason, D
5Gislason, T
6Gulsvik, A
7Janson, C
8Jögi, R
9Kiserud, T
10Norbäck, D
11Nyström, L
12Torén, K
13Wentzel-Larsen, T
14Omenaas, E
general
0BMJ Publishing Group Ltd and British Thoracic Society
1BMJ
2BMJ Publishing Group Ltd
3BMJ Publishing Group LTD
4BMJ Group
scope
0BSCLL
1IQODW
2CGR
3CUY
4CVF
5ECM
6EIF
7NPM
8AAYXX
9CITATION
10BSHEE
113V.
127X7
137XB
1488E
158FI
168FJ
178FK
18ABUWG
19BENPR
20BTHHO
21FYUFA
22GHDGH
23K9.
24M0S
25M1P
26PQEST
27PQQKQ
28PQUKI
29PRINS
307T5
31H94
32BOBZL
33CLFQK
345PM
35ADTPV
36AOWAS
sort
creationdate200601
titleHormone replacement therapy, body mass index and asthma in perimenopausal women: a cross sectional survey
authorGómez Real, F ; Svanes, C ; Björnsson, E H ; Franklin, K ; Gislason, D ; Gislason, T ; Gulsvik, A ; Janson, C ; Jögi, R ; Kiserud, T ; Norbäck, D ; Nyström, L ; Torén, K ; Wentzel-Larsen, T ; Omenaas, E
facets
frbrtype5
frbrgroupidcdi_FETCH-LOGICAL-1764t-79ff941077dc23e92bb96ea0ac6bcb76a61eea63f46ef15090348fac2198efc73
rsrctypearticles
prefilterarticles
languageeng
creationdate2006
topic
0Adult
1Asthma
2Asthma - chemically induced
3Asthma - etiology
4Asthma/chemically induced/etiology
5Biological and medical sciences
6BMI
7Body Mass Index
8Care and treatment
9Chronic obstructive pulmonary disease, asthma
10Complications and side effects
11Cross-Sectional Studies
12Development and progression
13ECRHS
14European Community Respiratory Health Survey
15Female
16hormone replacement therapy
17Hormone Replacement Therapy - adverse effects
18Hormone therapy
19HRT
20Humans
21insulin resistance
22Medical sciences
23Menopause
24Middle Aged
25Perimenopause
26Pneumology
27Questionnaires
28Respiratory Health in Northern Europe
29RHINE
30Rhinitis, Allergic, Seasonal - etiology
31Smoking - adverse effects
32Surveys and Questionnaires
toplevel
0peer_reviewed
1online_resources
creatorcontrib
0Gómez Real, F
1Svanes, C
2Björnsson, E H
3Franklin, K
4Gislason, D
5Gislason, T
6Gulsvik, A
7Janson, C
8Jögi, R
9Kiserud, T
10Norbäck, D
11Nyström, L
12Torén, K
13Wentzel-Larsen, T
14Omenaas, E
collection
0Istex
1Pascal-Francis
2Medline
3MEDLINE
4MEDLINE (Ovid)
5MEDLINE
6MEDLINE
7PubMed
8CrossRef
9Academic OneFile (A&I only)
10ProQuest Central (Corporate)
11Health & Medical Collection
12ProQuest Central (purchase pre-March 2016)
13Medical Database (Alumni Edition)
14Hospital Premium Collection
15Hospital Premium Collection (Alumni Edition)
16ProQuest Central (Alumni) (purchase pre-March 2016)
17ProQuest Central (Alumni Edition)
18ProQuest Central
19BMJ Journals
20Health Research Premium Collection
21Health Research Premium Collection (Alumni)
22ProQuest Health & Medical Complete (Alumni)
23Health & Medical Collection (Alumni Edition)
24Medical Database
25ProQuest One Academic Eastern Edition
26ProQuest One Academic
27ProQuest One Academic UKI Edition
28ProQuest Central China
29Immunology Abstracts
30AIDS and Cancer Research Abstracts
31OpenAIRE (Open Access)
32OpenAIRE
33PubMed Central (Full Participant titles)
34SwePub
35SwePub Articles
jtitleThorax
delivery
delcategoryRemote Search Resource
fulltextfulltext
addata
au
0Gómez Real, F
1Svanes, C
2Björnsson, E H
3Franklin, K
4Gislason, D
5Gislason, T
6Gulsvik, A
7Janson, C
8Jögi, R
9Kiserud, T
10Norbäck, D
11Nyström, L
12Torén, K
13Wentzel-Larsen, T
14Omenaas, E
formatjournal
genrearticle
ristypeJOUR
atitleHormone replacement therapy, body mass index and asthma in perimenopausal women: a cross sectional survey
jtitleThorax
addtitleThorax
date2006-01
risdate2006
volume61
issue1
spage34
epage40
pages34-40
issn0040-6376
eissn1468-3296
codenTHORA7
notesCorrespondence to:
 Dr F Gómez Real
 Department of Gynecology and Obstetrics, Haukeland University Hospital, 5021 Bergen, Norway; francisco.real@med.uib.no
abstractBackground: Hormone replacement therapy (HRT) and obesity both appear to increase the risk of asthma. A study was undertaken to investigate the association of HRT with asthma and hay fever in a population of perimenopausal women, focusing on a possible interaction with body mass index (BMI). Methods: A postal questionnaire was sent to population based samples in Denmark, Estonia, Iceland, Norway, and Sweden in 1999–2001, and 8588 women aged 25–54 years responded (77%). Pregnant women, women using oral contraceptives, and women <46 years were excluded. Analyses included 2206 women aged 46–54 years of which 884 were menopausal and 540 used HRT. Stratified analyses by BMI in tertiles were performed. Results: HRT was associated with an increased risk for asthma (OR 1.57 (95% CI 1.07 to 2.30)), wheeze (OR 1.60 (95% CI 1.22 to 2.10)), and hay fever (OR 1.48 (95% CI 1.15 to 1.90)). The associations with asthma and wheeze were significantly stronger among women with BMI in the lower tertile (asthma OR 2.41 (95% CI 1.21 to 4.77); wheeze OR 2.04 (95% CI 1.23 to 3.36)) than in heavier women (asthma: pinteraction = 0.030; wheeze: pinteraction = 0.042). Increasing BMI was associated with more asthma (OR 1.08 (95% CI 1.05 to 1.12) per kg/m2). This effect was only found in women not taking HRT (OR 1.10 (95% CI 1.05 to 1.14) per kg/m2); no such association was detected in HRT users (OR 1.00 (95% CI 0.92 to 1.08) per kg/m2) (pinteraction = 0.046). Menopause was not significantly associated with asthma, wheeze, or hay fever. Conclusions: In perimenopausal women there is an interaction between HRT and BMI in the effects on asthma. Lean women who were HRT users had as high a risk for asthma as overweight women not taking HRT. It is suggested that HRT and overweight increase the risk of asthma through partly common pathways.
copLondon
pubBMJ Publishing Group Ltd and British Thoracic Society
pmid16244093
doi10.1136/thx.2005.040881
oafree_for_read