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Global, regional, and national disability-adjusted life-years (DALYs) for 333 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016

Measurement of changes in health across locations is useful to compare and contrast changing epidemiological patterns against health system performance and identify specific needs for resource allocation in research, policy development, and programme decision making. Using the Global Burden of Disea... Full description

Journal Title: Lancet 2017, Vol.390 (10100), p.1260-1344
Main Author: Abate, Kalkidan Hassen
Other Authors: Abu-Raddad, Laith J , Adetokunboh, Olatunji , Afshin, Ashkan , Agrawal, Sutapa , Alkaabi, Juma M , Alla, François , Alsowaidi, Shirina , Ansha, Mustafa Geleto , Antonio, Carl Abelardo T , Asgedom, Solomon W , Awasthi, Shally , Bannick, Marlena S , Barac, Aleksandra , Baune, Bernhard T , Bensenor, Isabela M , Benson, Jennifer , Berhane, Adugnaw , Berhe, Derbew Fikadu , Blyth, Fiona M , Brainin, Michael , Cahuana-Hurtado, Lucero , Campos-Nonato, Ismael Ricardo , Carpenter, David O , Carter, Austin , Colombara, Danny , Dadi, Abel Fekadu , Dalal, Koustuv , Damasceno, Albertino , Dhillon, Preet K , Ebel, Beth E , Franklin, Richard C , Furtado, Joao M , Geleijnse, Johanna M , Ghajar, Alireza , Gillum, Richard F , Goel, Kashish , Hamidi, Samer , Haro, Josep Maria , Harun, Kimani M , Hendrie, Delia , Htet, Aung Soe , Karimi, Seyed M , Kesavachandran, Chandrasekharan Nair , Khubchandani, Jagdish , Knudsen, Ann Kristin , Kokubo, Yoshihiro , Koyanagi, Ai , Kumar, G Anil , Liu, Shiwei , Manhertz, Treh , Martinez-Raga, Jose , McGaughey, Madeline , Misganaw, Awoke , Mollenkopf, Sarah K , Nagel, Gabriele , Nasher, Jamal T , Natarajan, Gopalakrishnan , Nguyen, Minh , Noubiap, Jean Jacques N , Olagunju, Andrew Toyin , Pacella, Rosana E , Petri, William Arthur , Phillips, Michael Robert , Prasad, Narayan , Purcell, Carrie , Radfar, Amir , Rahman, Mahfuzar , Rajsic, Sasa , Sanabria, Juan Ramon , Santos, Itamar S , Schöttker, Ben , Seedat, Soraya , Shiferaw, Mekonnen Sisay , Shoman, Haitham , Sibai, Abla Mehio , Silveira, Dayane Gabriele Alves , Singh, Jasvinder A , Sinha, Dhirendra Narain , Slepak, Erica Leigh , Sobaih, Badr H A , Sur, Patrick J , Tabarés-Seisdedos, Rafael , Tadakamadla, Santosh Kumar , Tesfaye, Dawit Jember , Thompson, Robert , Tonelli, Marcello , Tran, Bach Xuan , Tuzcu, Emin Murat , Tyrovolas, Stefanos , Ukwaja, Kingsley Nnanna , Undurraga, Eduardo A , Updike, Rachel , Veerman, Lennert J , Vladimirov, Sergey K , Vlassov, Vasiliy Victorovich , Vollset, Stein Emil , Woolf, Anthony D , Zaki, Maysaa El Sayed , Murray, Christopher J L
Format: Electronic Article Electronic Article
Language: English
Subjects:
Age
dk
hiv
Men
Sex
VDP
Quelle: Alma/SFX Local Collection
Publisher: England: Elsevier Ltd
ID: ISSN: 0140-6736
Zum Text:
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title: Global, regional, and national disability-adjusted life-years (DALYs) for 333 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016
format: Article
creator:
  • Abate, Kalkidan Hassen
  • Abu-Raddad, Laith J
  • Adetokunboh, Olatunji
  • Afshin, Ashkan
  • Agrawal, Sutapa
  • Alkaabi, Juma M
  • Alla, François
  • Alsowaidi, Shirina
  • Ansha, Mustafa Geleto
  • Antonio, Carl Abelardo T
  • Asgedom, Solomon W
  • Awasthi, Shally
  • Bannick, Marlena S
  • Barac, Aleksandra
  • Baune, Bernhard T
  • Bensenor, Isabela M
  • Benson, Jennifer
  • Berhane, Adugnaw
  • Berhe, Derbew Fikadu
  • Blyth, Fiona M
  • Brainin, Michael
  • Cahuana-Hurtado, Lucero
  • Campos-Nonato, Ismael Ricardo
  • Carpenter, David O
  • Carter, Austin
  • Colombara, Danny
  • Dadi, Abel Fekadu
  • Dalal, Koustuv
  • Damasceno, Albertino
  • Dhillon, Preet K
  • Ebel, Beth E
  • Franklin, Richard C
  • Furtado, Joao M
  • Geleijnse, Johanna M
  • Ghajar, Alireza
  • Gillum, Richard F
  • Goel, Kashish
  • Hamidi, Samer
  • Haro, Josep Maria
  • Harun, Kimani M
  • Hendrie, Delia
  • Htet, Aung Soe
  • Karimi, Seyed M
  • Kesavachandran, Chandrasekharan Nair
  • Khubchandani, Jagdish
  • Knudsen, Ann Kristin
  • Kokubo, Yoshihiro
  • Koyanagi, Ai
  • Kumar, G Anil
  • Liu, Shiwei
  • Manhertz, Treh
  • Martinez-Raga, Jose
  • McGaughey, Madeline
  • Misganaw, Awoke
  • Mollenkopf, Sarah K
  • Nagel, Gabriele
  • Nasher, Jamal T
  • Natarajan, Gopalakrishnan
  • Nguyen, Minh
  • Noubiap, Jean Jacques N
  • Olagunju, Andrew Toyin
  • Pacella, Rosana E
  • Petri, William Arthur
  • Phillips, Michael Robert
  • Prasad, Narayan
  • Purcell, Carrie
  • Radfar, Amir
  • Rahman, Mahfuzar
  • Rajsic, Sasa
  • Sanabria, Juan Ramon
  • Santos, Itamar S
  • Schöttker, Ben
  • Seedat, Soraya
  • Shiferaw, Mekonnen Sisay
  • Shoman, Haitham
  • Sibai, Abla Mehio
  • Silveira, Dayane Gabriele Alves
  • Singh, Jasvinder A
  • Sinha, Dhirendra Narain
  • Slepak, Erica Leigh
  • Sobaih, Badr H A
  • Sur, Patrick J
  • Tabarés-Seisdedos, Rafael
  • Tadakamadla, Santosh Kumar
  • Tesfaye, Dawit Jember
  • Thompson, Robert
  • Tonelli, Marcello
  • Tran, Bach Xuan
  • Tuzcu, Emin Murat
  • Tyrovolas, Stefanos
  • Ukwaja, Kingsley Nnanna
  • Undurraga, Eduardo A
  • Updike, Rachel
  • Veerman, Lennert J
  • Vladimirov, Sergey K
  • Vlassov, Vasiliy Victorovich
  • Vollset, Stein Emil
  • Woolf, Anthony D
  • Zaki, Maysaa El Sayed
  • Murray, Christopher J L
subjects:
  • 11 Medical And Health Sciences
  • 3112 Neurosciences
  • 3121 Internal medicine
  • 3122 Cancers
  • 3142 Public health care science
  • 80 and over
  • Cause of Death
  • Communicable Diseases
  • Disabled Persons
  • Female
  • Global Burden of Disease
  • Global Health
  • Humans
  • Life Expectancy
  • Male
  • Middle Aged
  • Noncommunicable Diseases
  • Quality-Adjusted Life Years
  • Residence Characteristics
  • Sex Distribution
  • Wounds and Injuries
  • abdominal wall hernia
  • abortion
  • accommodation disorder
  • acne vulgaris
  • acquired immune deficiency syndrome
  • acute glomerulonephritis
  • acute hepatitis A
  • acute hepatitis e
  • acute lymphoblastic leukemia
  • acute myeloid leukemia
  • adolescent
  • adult
  • African trypanosomiasis
  • aged
  • alcoholic cardiomyopathy
  • alcoholism
  • all cause mortality
  • alopecia areata
  • Alzheimer disease
  • amphetamine dependence
  • anorexia nervosa
  • anxiety disorder
  • aortic aneurysm
  • appendicitis
  • Article
  • asbestosis
  • ascariasis
  • Asperger syndrome
  • asthma
  • atrial fibrillation
  • attention deficit disorder
  • autism
  • automutilation
  • biliary tract cancer
  • biliary tract disease
  • bipolar disorder
  • bladder cancer
  • brain cancer
  • brain hemorrhage
  • brain ischemia
  • breast cancer
  • bronchus cancer
  • bulimia
  • cardiomyopathy
  • cataract
  • cause of death
  • cellulitis
  • cerebrovascular disease
  • Chagas disease
  • chickenpox
  • child
  • chlamydiasis
  • chronic kidney failure
  • chronic liver disease
  • chronic lymphatic leukemia
  • chronic myeloid leukemia
  • chronic obstructive lung disease
  • coal workers’ pneumoconiosis
  • cocaine dependence
  • colon cancer
  • conduct disorder
  • congenital disorder
  • cysticercosis
  • decubitus
  • dengue
  • dental caries
  • dermatitis
  • diabetes mellitus
  • diarrhea
  • diphtheria
  • disability-adjusted life year
  • disease course
  • diseases
  • Down syndrome
  • dracunculiasis
  • drowning
  • drug dependence
  • drug resistant tuberculosis
  • duodenitis
  • dysthymia
  • eating disorder
  • Ebola hemorrhagic fever
  • echinococcosis
  • ectopic pregnancy
  • encephalitis
  • endocarditis
  • endometriosis
  • epidemic meningitis
  • epilepsy
  • esophagus cancer
  • falling
  • female
  • female infertility
  • femoral hernia
  • food borne trematodiasis
  • foreign body
  • fungal skin disease
  • gallbladder cancer
  • gallbladder disease
  • gastritis
  • genital herpes
  • glaucoma
  • global disease burden
  • glucose 6 phosphate dehydrogenase deficiency
  • gonorrhea
  • gout
  • gross national product
  • groups by age
  • gunshot injury
  • haemophilus influenzae type b meningitis
  • health care policy
  • healthy life expectancy
  • hearing impairment
  • heart atrium flutter
  • hemolytic anemia
  • hepatitis
  • hepatitis B
  • hepatitis C
  • herpes zoster
  • Hodgkin disease
  • hookworm infection
  • human
  • Human immunodeficiency virus infection
  • ICD-10
  • ICD-9
  • inflammatory bowel disease
  • inguinal hernia
  • injury
  • intellectual impairment
  • interstitial lung disease
  • interstitial nephritis
  • intestine infection
  • intestine obstruction
  • intoxication
  • iodine deficiency
  • iron deficiency anemia
  • ischemic heart disease
  • kidney cancer
  • larynx cancer
  • latent tuberculosis
  • leishmaniasis
  • leprosy
  • leukemia
  • life expectancy
  • lip cancer
  • liver cancer
  • liver cirrhosis
  • low back pain
  • low income country
  • lower respiratory tract infection
  • lung cancer
  • lung sarcoidosis
  • lymphatic filariasis
  • macular degeneration
  • major clinical study
  • major depression
  • malaria
  • male
  • male infertility
  • malignant neoplasm
  • maternal death
  • maternal hemorrhage
  • maternal hypertension
  • measles
  • melanoma
  • meningitis
  • mesothelioma
  • middle income country
  • migraine
  • morbidity
  • motor neuron disease
  • mouth cancer
  • mouth malformation
  • mucocutaneous leishmaniasis
  • multiple myeloma
  • multiple sclerosis
  • myocarditis
  • nasopharynx cancer
  • neck pain
  • neglected disease
  • nematodiasis
  • neonatal encephalopathy
  • neural tube defect
  • newborn disease
  • newborn jaundice
  • newborn sepsis
  • nonhodgkin lymphoma
  • onchocerciasis
  • opiate addiction
  • osteoarthritis
  • otitis media
  • ovary cancer
  • pancreas cancer
  • pancreatitis
  • paralytic ileus
  • paratyphoid fever
  • Parkinson disease
  • pelvic organ prolapse
  • peptic ulcer
  • perinatal asphyxia
  • periodontal disease
  • peripheral occlusive artery disease
  • pertussis
  • physical violence
  • pneumococcal meningitis
  • pneumoconiosis
  • premature labor
  • premenstrual syndrome
  • priority journal
  • prostate cancer
  • prostate hypertrophy
  • protein calorie malnutrition
  • pruritus
  • psoriasis
  • pulmonary aspiration
  • pyoderma
  • rectum cancer
  • refraction error
  • retinol deficiency
  • rheumatic heart disease
  • rheumatoid arthritis
  • risk factor
  • scabies
  • schistosomiasis
  • schizophrenia
  • sickle cell trait
  • silicosis
  • skin leishmaniasis
  • spontaneous abortion
  • stomach cancer
  • sudden infant death syndrome
  • suffocation
  • syphilis
  • tension headache
  • terrorism
  • testis cancer
  • tetanus
  • thalassemia
  • thyroid cancer
  • trachea cancer
  • trachoma
  • traffic accident
  • trematodiasis
  • trichomoniasis
  • trichuriasis
  • tuberculosis
  • Turner syndrome
  • typhoid fever
  • upper respiratory tract infection
  • urinary tract infection
  • urticaria
  • uterine cervix cancer
  • uterus cancer
  • uterus myoma
  • uterus rupture
  • viral skin disease
  • visceral leishmaniasis
  • yellow fever
  • Zika fever
  • age distribution
  • communicable disease
  • demography
  • disabled person
  • global disease burden
  • global health
  • injury
  • life expectancy
  • middle aged
  • mortality
  • non communicable disease
  • quality adjusted life year
  • sex ratio
  • statistics and numerical data
  • trends
  • very elderly
  • Adjusted Life Years
  • Adult
  • Adult
  • Age Distribution
  • Aged
  • Aged
  • Adults
  • africa
  • Age
  • Age Distribution
  • Aged
  • Aged, 80 and over
  • Aldraðir
  • Allmänmedicin
  • Analysis
  • asjc
  • association
  • atira
  • australia
  • Benchmarks
  • Cause of Death
  • Cause of Death - trends
  • changes in health
  • Charities
  • Clinical Medicine
  • Communicable Diseases
  • Communicable Diseases - mortality
  • Compression
  • Coronary artery disease
  • Decision making
  • Demographics
  • Disability
  • Disabled Persons
  • Disabled Persons - statistics & numerical data
  • Disease
  • Diseases
  • dk
  • Dánarmein
  • environmental
  • epidemiologic transition
  • Epidemiology
  • Family planning
  • Faraldsfræði
  • Fatlaðir
  • Female
  • Females
  • Fertility
  • Folkhälsovetenskap
  • Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi
  • Fullorðnir
  • Félagshagfræði
  • General & Internal
  • General & Internal Medicine
  • General Practice
  • Global Burden of Disease
  • Global Burden of Disease - statistics & numerical data
  • Global Health
  • Global Health - statistics & numerical data
  • Global Health Metrics
  • Global Helse
  • Global Helse / Global Health
  • global hälsa
  • Halk Sağlığı
  • health administration research
  • Health and Welfare
  • Health aspects
  • Health care
  • Health care science
  • Health policy
  • Health risks
  • Health Sciences
  • Health sciences: 800
  • Health service
  • Health service and health administration research: 806
  • Health Services Administration
  • healthy life expectancy
  • Heart diseases
  • Heilbrigðisstefna
  • Heilsufar
  • Helse
  • Helse- og sykehusadministrasjon / Health Services Administration
  • Helsefag
  • Helsefag: 800
  • Helsepolitikk
  • Helsepolitikk / Health policy
  • Helsetjeneste
  • Helsetjeneste- og helseadministrasjonsforskning: 806
  • hiv
  • Humans
  • Hälsa och välfärd
  • Hälsovetenskap
  • Hälsovetenskaper
  • Injuries
  • Journal Article
  • Karlar
  • Klinisk medicin
  • Konur
  • Life Expectancy
  • Life Sciences & Biomedicine
  • Life span
  • Lífsgæði
  • Lífslíkur
  • Lýðheilsa
  • Male
  • Males
  • Mathematical analysis
  • Medical and Health Sciences
  • Medical research
  • Medicin och hälsovetenskap
  • Medicine
  • Medicine(all)
  • Medicine, Experimental
  • Medisinske fag
  • Medisinske fag: 700
  • Men
  • Mental health
  • Middle Aged
  • Midical sciences
  • Midical sciences: 700
  • Morbidity
  • Mortality
  • Neonates
  • Noncommunicable Diseases
  • Noncommunicable Diseases - mortality
  • occupational health
  • og helseadministrasjonsforskning
  • og sykehusadministrasjon
  • Older people
  • over
  • People with disabilities
  • plasmodium-falciparum
  • Population
  • prevalence
  • Public Health
  • Public Health, Global Health, Social Medicine and Epidemiology
  • pubmedpublicationtype
  • pure
  • Quality
  • Quality of life
  • Quality-Adjusted Life Years
  • researchoutput
  • Residence Characteristics
  • Residence Characteristics - statistics & numerical data
  • Resource allocation
  • Risk analysis
  • Risk factors
  • Science & Technology
  • SDG 3 - Good Health and Well-being
  • Sex
  • Sex Distribution
  • Sjúkdómar
  • Social ecology
  • Social Medicine
  • socialmedicin och epidemiologi
  • Sociodemographics
  • statistics
  • statistics & numerical data
  • subjectarea
  • Terveystiede
  • therapy
  • Trends
  • Tölfræði
  • VDP
  • weights
  • Women
  • World health
  • Wounds
  • Wounds and Injuries - mortality
  • Áverkar
  • Þjóðir
ispartof: Lancet, 2017, Vol.390 (10100), p.1260-1344
description: Measurement of changes in health across locations is useful to compare and contrast changing epidemiological patterns against health system performance and identify specific needs for resource allocation in research, policy development, and programme decision making. Using the Global Burden of Diseases, Injuries, and Risk Factors Study 2016, we drew from two widely used summary measures to monitor such changes in population health: disability-adjusted life-years (DALYs) and healthy life expectancy (HALE). We used these measures to track trends and benchmark progress compared with expected trends on the basis of the Socio-demographic Index (SDI). We used results from the Global Burden of Diseases, Injuries, and Risk Factors Study 2016 for all-cause mortality, cause-specific mortality, and non-fatal disease burden to derive HALE and DALYs by sex for 195 countries and territories from 1990 to 2016. We calculated DALYs by summing years of life lost and years of life lived with disability for each location, age group, sex, and year. We estimated HALE using age-specific death rates and years of life lived with disability per capita. We explored how DALYs and HALE differed from expected trends when compared with the SDI: the geometric mean of income per person, educational attainment in the population older than age 15 years, and total fertility rate. The highest globally observed HALE at birth for both women and men was in Singapore, at 75·2 years (95% uncertainty interval 71·9–78·6) for females and 72·0 years (68·8–75·1) for males. The lowest for females was in the Central African Republic (45·6 years [42·0–49·5]) and for males was in Lesotho (41·5 years [39·0–44·0]). From 1990 to 2016, global HALE increased by an average of 6·24 years (5·97–6·48) for both sexes combined. Global HALE increased by 6·04 years (5·74–6·27) for males and 6·49 years (6·08–6·77) for females, whereas HALE at age 65 years increased by 1·78 years (1·61–1·93) for males and 1·96 years (1·69–2·13) for females. Total global DALYs remained largely unchanged from 1990 to 2016 (–2·3% [–5·9 to 0·9]), with decreases in communicable, maternal, neonatal, and nutritional (CMNN) disease DALYs offset by increased DALYs due to non-communicable diseases (NCDs). The exemplars, calculated as the five lowest ratios of observed to expected age-standardised DALY rates in 2016, were Nicaragua, Costa Rica, the Maldives, Peru, and Israel. The leading three causes of DALYs globally were ischaemic heart disease,
language: eng
source: Alma/SFX Local Collection
identifier: ISSN: 0140-6736
fulltext: fulltext
issn:
  • 0140-6736
  • 1474-547X
  • 1474-547X
url: Link


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titleGlobal, regional, and national disability-adjusted life-years (DALYs) for 333 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016
sourceAlma/SFX Local Collection
creatorAbate, Kalkidan Hassen ; Abu-Raddad, Laith J ; Adetokunboh, Olatunji ; Afshin, Ashkan ; Agrawal, Sutapa ; Alkaabi, Juma M ; Alla, François ; Alsowaidi, Shirina ; Ansha, Mustafa Geleto ; Antonio, Carl Abelardo T ; Asgedom, Solomon W ; Awasthi, Shally ; Bannick, Marlena S ; Barac, Aleksandra ; Baune, Bernhard T ; Bensenor, Isabela M ; Benson, Jennifer ; Berhane, Adugnaw ; Berhe, Derbew Fikadu ; Blyth, Fiona M ; Brainin, Michael ; Cahuana-Hurtado, Lucero ; Campos-Nonato, Ismael Ricardo ; Carpenter, David O ; Carter, Austin ; Colombara, Danny ; Dadi, Abel Fekadu ; Dalal, Koustuv ; Damasceno, Albertino ; Dhillon, Preet K ; Ebel, Beth E ; Franklin, Richard C ; Furtado, Joao M ; Geleijnse, Johanna M ; Ghajar, Alireza ; Gillum, Richard F ; Goel, Kashish ; Hamidi, Samer ; Haro, Josep Maria ; Harun, Kimani M ; Hendrie, Delia ; Htet, Aung Soe ; Karimi, Seyed M ; Kesavachandran, Chandrasekharan Nair ; Khubchandani, Jagdish ; Knudsen, Ann Kristin ; Kokubo, Yoshihiro ; Koyanagi, Ai ; Kumar, G Anil ; Liu, Shiwei ; Manhertz, Treh ; Martinez-Raga, Jose ; McGaughey, Madeline ; Misganaw, Awoke ; Mollenkopf, Sarah K ; Nagel, Gabriele ; Nasher, Jamal T ; Natarajan, Gopalakrishnan ; Nguyen, Minh ; Noubiap, Jean Jacques N ; Olagunju, Andrew Toyin ; Pacella, Rosana E ; Petri, William Arthur ; Phillips, Michael Robert ; Prasad, Narayan ; Purcell, Carrie ; Radfar, Amir ; Rahman, Mahfuzar ; Rajsic, Sasa ; Sanabria, Juan Ramon ; Santos, Itamar S ; Schöttker, Ben ; Seedat, Soraya ; Shiferaw, Mekonnen Sisay ; Shoman, Haitham ; Sibai, Abla Mehio ; Silveira, Dayane Gabriele Alves ; Singh, Jasvinder A ; Sinha, Dhirendra Narain ; Slepak, Erica Leigh ; Sobaih, Badr H A ; Sur, Patrick J ; Tabarés-Seisdedos, Rafael ; Tadakamadla, Santosh Kumar ; Tesfaye, Dawit Jember ; Thompson, Robert ; Tonelli, Marcello ; Tran, Bach Xuan ; Tuzcu, Emin Murat ; Tyrovolas, Stefanos ; Ukwaja, Kingsley Nnanna ; Undurraga, Eduardo A ; Updike, Rachel ; Veerman, Lennert J ; Vladimirov, Sergey K ; Vlassov, Vasiliy Victorovich ; Vollset, Stein Emil ; Woolf, Anthony D ; Zaki, Maysaa El Sayed ; Murray, Christopher J L
creatorcontribAbate, Kalkidan Hassen ; Abu-Raddad, Laith J ; Adetokunboh, Olatunji ; Afshin, Ashkan ; Agrawal, Sutapa ; Alkaabi, Juma M ; Alla, François ; Alsowaidi, Shirina ; Ansha, Mustafa Geleto ; Antonio, Carl Abelardo T ; Asgedom, Solomon W ; Awasthi, Shally ; Bannick, Marlena S ; Barac, Aleksandra ; Baune, Bernhard T ; Bensenor, Isabela M ; Benson, Jennifer ; Berhane, Adugnaw ; Berhe, Derbew Fikadu ; Blyth, Fiona M ; Brainin, Michael ; Cahuana-Hurtado, Lucero ; Campos-Nonato, Ismael Ricardo ; Carpenter, David O ; Carter, Austin ; Colombara, Danny ; Dadi, Abel Fekadu ; Dalal, Koustuv ; Damasceno, Albertino ; Dhillon, Preet K ; Ebel, Beth E ; Franklin, Richard C ; Furtado, Joao M ; Geleijnse, Johanna M ; Ghajar, Alireza ; Gillum, Richard F ; Goel, Kashish ; Hamidi, Samer ; Haro, Josep Maria ; Harun, Kimani M ; Hendrie, Delia ; Htet, Aung Soe ; Karimi, Seyed M ; Kesavachandran, Chandrasekharan Nair ; Khubchandani, Jagdish ; Knudsen, Ann Kristin ; Kokubo, Yoshihiro ; Koyanagi, Ai ; Kumar, G Anil ; Liu, Shiwei ; Manhertz, Treh ; Martinez-Raga, Jose ; McGaughey, Madeline ; Misganaw, Awoke ; Mollenkopf, Sarah K ; Nagel, Gabriele ; Nasher, Jamal T ; Natarajan, Gopalakrishnan ; Nguyen, Minh ; Noubiap, Jean Jacques N ; Olagunju, Andrew Toyin ; Pacella, Rosana E ; Petri, William Arthur ; Phillips, Michael Robert ; Prasad, Narayan ; Purcell, Carrie ; Radfar, Amir ; Rahman, Mahfuzar ; Rajsic, Sasa ; Sanabria, Juan Ramon ; Santos, Itamar S ; Schöttker, Ben ; Seedat, Soraya ; Shiferaw, Mekonnen Sisay ; Shoman, Haitham ; Sibai, Abla Mehio ; Silveira, Dayane Gabriele Alves ; Singh, Jasvinder A ; Sinha, Dhirendra Narain ; Slepak, Erica Leigh ; Sobaih, Badr H A ; Sur, Patrick J ; Tabarés-Seisdedos, Rafael ; Tadakamadla, Santosh Kumar ; Tesfaye, Dawit Jember ; Thompson, Robert ; Tonelli, Marcello ; Tran, Bach Xuan ; Tuzcu, Emin Murat ; Tyrovolas, Stefanos ; Ukwaja, Kingsley Nnanna ; Undurraga, Eduardo A ; Updike, Rachel ; Veerman, Lennert J ; Vladimirov, Sergey K ; Vlassov, Vasiliy Victorovich ; Vollset, Stein Emil ; Woolf, Anthony D ; Zaki, Maysaa El Sayed ; Murray, Christopher J L ; GBD 2016 DALYs and HALE Collaborators ; Sahlgrenska akademin ; Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa, enheten för hälsometri ; Institute of Medicine, Department of Public Health and Community Medicine, Health Metrics ; Göteborgs universitet ; Gothenburg University ; Sahlgrenska Academy
descriptionMeasurement of changes in health across locations is useful to compare and contrast changing epidemiological patterns against health system performance and identify specific needs for resource allocation in research, policy development, and programme decision making. Using the Global Burden of Diseases, Injuries, and Risk Factors Study 2016, we drew from two widely used summary measures to monitor such changes in population health: disability-adjusted life-years (DALYs) and healthy life expectancy (HALE). We used these measures to track trends and benchmark progress compared with expected trends on the basis of the Socio-demographic Index (SDI). We used results from the Global Burden of Diseases, Injuries, and Risk Factors Study 2016 for all-cause mortality, cause-specific mortality, and non-fatal disease burden to derive HALE and DALYs by sex for 195 countries and territories from 1990 to 2016. We calculated DALYs by summing years of life lost and years of life lived with disability for each location, age group, sex, and year. We estimated HALE using age-specific death rates and years of life lived with disability per capita. We explored how DALYs and HALE differed from expected trends when compared with the SDI: the geometric mean of income per person, educational attainment in the population older than age 15 years, and total fertility rate. The highest globally observed HALE at birth for both women and men was in Singapore, at 75·2 years (95% uncertainty interval 71·9–78·6) for females and 72·0 years (68·8–75·1) for males. The lowest for females was in the Central African Republic (45·6 years [42·0–49·5]) and for males was in Lesotho (41·5 years [39·0–44·0]). From 1990 to 2016, global HALE increased by an average of 6·24 years (5·97–6·48) for both sexes combined. Global HALE increased by 6·04 years (5·74–6·27) for males and 6·49 years (6·08–6·77) for females, whereas HALE at age 65 years increased by 1·78 years (1·61–1·93) for males and 1·96 years (1·69–2·13) for females. Total global DALYs remained largely unchanged from 1990 to 2016 (–2·3% [–5·9 to 0·9]), with decreases in communicable, maternal, neonatal, and nutritional (CMNN) disease DALYs offset by increased DALYs due to non-communicable diseases (NCDs). The exemplars, calculated as the five lowest ratios of observed to expected age-standardised DALY rates in 2016, were Nicaragua, Costa Rica, the Maldives, Peru, and Israel. The leading three causes of DALYs globally were ischaemic heart disease, cerebrovascular disease, and lower respiratory infections, comprising 16·1% of all DALYs. Total DALYs and age-standardised DALY rates due to most CMNN causes decreased from 1990 to 2016. Conversely, the total DALY burden rose for most NCDs; however, age-standardised DALY rates due to NCDs declined globally. At a global level, DALYs and HALE continue to show improvements. At the same time, we observe that many populations are facing growing functional health loss. Rising SDI was associated with increases in cumulative years of life lived with disability and decreases in CMNN DALYs offset by increased NCD DALYs. Relative compression of morbidity highlights the importance of continued health interventions, which has changed in most locations in pace with the gross domestic product per person, education, and family planning. The analysis of DALYs and HALE and their relationship to SDI represents a robust framework with which to benchmark location-specific health performance. Country-specific drivers of disease burden, particularly for causes with higher-than-expected DALYs, should inform health policies, health system improvement initiatives, targeted prevention efforts, and development assistance for health, including financial and research investments for all countries, regardless of their level of sociodemographic development. The presence of countries that substantially outperform others suggests the need for increased scrutiny for proven examples of best practices, which can help to extend gains, whereas the presence of underperforming countries suggests the need for devotion of extra attention to health systems that need more robust support. Bill & Melinda Gates Foundation.
identifier
0ISSN: 0140-6736
1ISSN: 1474-547X
2EISSN: 1474-547X
3DOI: 10.1016/S0140-6736(17)32130-X
4PMID: 28919118
languageeng
publisherEngland: Elsevier Ltd
subject
ispartofLancet, 2017, Vol.390 (10100), p.1260-1344
rights
02017 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license
1info:eu-repo/semantics/restrictedAccess
2Copyright © 2017 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license. Published by Elsevier Ltd.. All rights reserved.
3COPYRIGHT 2017 Elsevier B.V.
4Copyright Elsevier Limited Sep 16, 2017
5info:eu-repo/semantics/openAccess
62017 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license 2017
lds50peer_reviewed
oafree_for_read
citedbyFETCH-LOGICAL-12878t-15020f0ac4f1bd733edaeeb9b5b78c6185e01394286c5c8fa548c9744eb8ba623
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search
creatorcontrib
0Abate, Kalkidan Hassen
1Abu-Raddad, Laith J
2Adetokunboh, Olatunji
3Afshin, Ashkan
4Agrawal, Sutapa
5Alkaabi, Juma M
6Alla, François
7Alsowaidi, Shirina
8Ansha, Mustafa Geleto
9Antonio, Carl Abelardo T
10Asgedom, Solomon W
11Awasthi, Shally
12Bannick, Marlena S
13Barac, Aleksandra
14Baune, Bernhard T
15Bensenor, Isabela M
16Benson, Jennifer
17Berhane, Adugnaw
18Berhe, Derbew Fikadu
19Blyth, Fiona M
20Brainin, Michael
21Cahuana-Hurtado, Lucero
22Campos-Nonato, Ismael Ricardo
23Carpenter, David O
24Carter, Austin
25Colombara, Danny
26Dadi, Abel Fekadu
27Dalal, Koustuv
28Damasceno, Albertino
29Dhillon, Preet K
30Ebel, Beth E
31Franklin, Richard C
32Furtado, Joao M
33Geleijnse, Johanna M
34Ghajar, Alireza
35Gillum, Richard F
36Goel, Kashish
37Hamidi, Samer
38Haro, Josep Maria
39Harun, Kimani M
40Hendrie, Delia
41Htet, Aung Soe
42Karimi, Seyed M
43Kesavachandran, Chandrasekharan Nair
44Khubchandani, Jagdish
45Knudsen, Ann Kristin
46Kokubo, Yoshihiro
47Koyanagi, Ai
48Kumar, G Anil
49Liu, Shiwei
50Manhertz, Treh
51Martinez-Raga, Jose
52McGaughey, Madeline
53Misganaw, Awoke
54Mollenkopf, Sarah K
55Nagel, Gabriele
56Nasher, Jamal T
57Natarajan, Gopalakrishnan
58Nguyen, Minh
59Noubiap, Jean Jacques N
60Olagunju, Andrew Toyin
61Pacella, Rosana E
62Petri, William Arthur
63Phillips, Michael Robert
64Prasad, Narayan
65Purcell, Carrie
66Radfar, Amir
67Rahman, Mahfuzar
68Rajsic, Sasa
69Sanabria, Juan Ramon
70Santos, Itamar S
71Schöttker, Ben
72Seedat, Soraya
73Shiferaw, Mekonnen Sisay
74Shoman, Haitham
75Sibai, Abla Mehio
76Silveira, Dayane Gabriele Alves
77Singh, Jasvinder A
78Sinha, Dhirendra Narain
79Slepak, Erica Leigh
80Sobaih, Badr H A
81Sur, Patrick J
82Tabarés-Seisdedos, Rafael
83Tadakamadla, Santosh Kumar
84Tesfaye, Dawit Jember
85Thompson, Robert
86Tonelli, Marcello
87Tran, Bach Xuan
88Tuzcu, Emin Murat
89Tyrovolas, Stefanos
90Ukwaja, Kingsley Nnanna
91Undurraga, Eduardo A
92Updike, Rachel
93Veerman, Lennert J
94Vladimirov, Sergey K
95Vlassov, Vasiliy Victorovich
96Vollset, Stein Emil
97Woolf, Anthony D
98Zaki, Maysaa El Sayed
99Murray, Christopher J L
100GBD 2016 DALYs and HALE Collaborators
101Sahlgrenska akademin
102Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa, enheten för hälsometri
103Institute of Medicine, Department of Public Health and Community Medicine, Health Metrics
104Göteborgs universitet
105Gothenburg University
106Sahlgrenska Academy
title
0Global, regional, and national disability-adjusted life-years (DALYs) for 333 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016
1Lancet
addtitleLancet
descriptionMeasurement of changes in health across locations is useful to compare and contrast changing epidemiological patterns against health system performance and identify specific needs for resource allocation in research, policy development, and programme decision making. Using the Global Burden of Diseases, Injuries, and Risk Factors Study 2016, we drew from two widely used summary measures to monitor such changes in population health: disability-adjusted life-years (DALYs) and healthy life expectancy (HALE). We used these measures to track trends and benchmark progress compared with expected trends on the basis of the Socio-demographic Index (SDI). We used results from the Global Burden of Diseases, Injuries, and Risk Factors Study 2016 for all-cause mortality, cause-specific mortality, and non-fatal disease burden to derive HALE and DALYs by sex for 195 countries and territories from 1990 to 2016. We calculated DALYs by summing years of life lost and years of life lived with disability for each location, age group, sex, and year. We estimated HALE using age-specific death rates and years of life lived with disability per capita. We explored how DALYs and HALE differed from expected trends when compared with the SDI: the geometric mean of income per person, educational attainment in the population older than age 15 years, and total fertility rate. The highest globally observed HALE at birth for both women and men was in Singapore, at 75·2 years (95% uncertainty interval 71·9–78·6) for females and 72·0 years (68·8–75·1) for males. The lowest for females was in the Central African Republic (45·6 years [42·0–49·5]) and for males was in Lesotho (41·5 years [39·0–44·0]). From 1990 to 2016, global HALE increased by an average of 6·24 years (5·97–6·48) for both sexes combined. Global HALE increased by 6·04 years (5·74–6·27) for males and 6·49 years (6·08–6·77) for females, whereas HALE at age 65 years increased by 1·78 years (1·61–1·93) for males and 1·96 years (1·69–2·13) for females. Total global DALYs remained largely unchanged from 1990 to 2016 (–2·3% [–5·9 to 0·9]), with decreases in communicable, maternal, neonatal, and nutritional (CMNN) disease DALYs offset by increased DALYs due to non-communicable diseases (NCDs). The exemplars, calculated as the five lowest ratios of observed to expected age-standardised DALY rates in 2016, were Nicaragua, Costa Rica, the Maldives, Peru, and Israel. The leading three causes of DALYs globally were ischaemic heart disease, cerebrovascular disease, and lower respiratory infections, comprising 16·1% of all DALYs. Total DALYs and age-standardised DALY rates due to most CMNN causes decreased from 1990 to 2016. Conversely, the total DALY burden rose for most NCDs; however, age-standardised DALY rates due to NCDs declined globally. At a global level, DALYs and HALE continue to show improvements. At the same time, we observe that many populations are facing growing functional health loss. Rising SDI was associated with increases in cumulative years of life lived with disability and decreases in CMNN DALYs offset by increased NCD DALYs. Relative compression of morbidity highlights the importance of continued health interventions, which has changed in most locations in pace with the gross domestic product per person, education, and family planning. The analysis of DALYs and HALE and their relationship to SDI represents a robust framework with which to benchmark location-specific health performance. Country-specific drivers of disease burden, particularly for causes with higher-than-expected DALYs, should inform health policies, health system improvement initiatives, targeted prevention efforts, and development assistance for health, including financial and research investments for all countries, regardless of their level of sociodemographic development. The presence of countries that substantially outperform others suggests the need for increased scrutiny for proven examples of best practices, which can help to extend gains, whereas the presence of underperforming countries suggests the need for devotion of extra attention to health systems that need more robust support. Bill & Melinda Gates Foundation.
subject
011 Medical And Health Sciences
13112 Neurosciences
23121 Internal medicine
33122 Cancers
43142 Public health care science
580 and over; Cause of Death; Communicable Diseases; Disabled Persons; Female; Global Burden of Disease; Global Health; Humans; Life Expectancy; Male; Middle Aged; Noncommunicable Diseases; Quality-Adjusted Life Years; Residence Characteristics; Sex Distribution; Wounds and Injuries
6abdominal wall hernia; abortion; accommodation disorder; acne vulgaris; acquired immune deficiency syndrome; acute glomerulonephritis; acute hepatitis A; acute hepatitis e; acute lymphoblastic leukemia; acute myeloid leukemia; adolescent; adult; African trypanosomiasis; aged; alcoholic cardiomyopathy; alcoholism; all cause mortality; alopecia areata; Alzheimer disease; amphetamine dependence; anorexia nervosa; anxiety disorder; aortic aneurysm; appendicitis; Article; asbestosis; ascariasis; Asperger syndrome; asthma; atrial fibrillation; attention deficit disorder; autism; automutilation; biliary tract cancer; biliary tract disease; bipolar disorder; bladder cancer; brain cancer; brain hemorrhage; brain ischemia; breast cancer; bronchus cancer; bulimia; cardiomyopathy; cataract; cause of death; cellulitis; cerebrovascular disease; Chagas disease; chickenpox; child; chlamydiasis; chronic kidney failure; chronic liver disease; chronic lymphatic leukemia; chronic myeloid leukemia; chronic obstructive lung disease; coal workers’ pneumoconiosis; cocaine dependence; colon cancer; conduct disorder; congenital disorder; cysticercosis; decubitus; dengue; dental caries; dermatitis; diabetes mellitus; diarrhea; diphtheria; disability-adjusted life year; disease course; diseases; Down syndrome; dracunculiasis; drowning; drug dependence; drug resistant tuberculosis; duodenitis; dysthymia; eating disorder; Ebola hemorrhagic fever; echinococcosis; ectopic pregnancy; encephalitis; endocarditis; endometriosis; epidemic meningitis; epilepsy; esophagus cancer; falling; female; female infertility; femoral hernia; food borne trematodiasis; foreign body; fungal skin disease; gallbladder cancer; gallbladder disease; gastritis; genital herpes; glaucoma; global disease burden; glucose 6 phosphate dehydrogenase deficiency; gonorrhea; gout; gross national product; groups by age; gunshot injury; haemophilus influenzae type b meningitis; health care policy; healthy life expectancy; hearing impairment; heart atrium flutter; hemolytic anemia; hepatitis; hepatitis B; hepatitis C; herpes zoster; Hodgkin disease; hookworm infection; human; Human immunodeficiency virus infection; ICD-10; ICD-9; inflammatory bowel disease; inguinal hernia; injury; intellectual impairment; interstitial lung disease; interstitial nephritis; intestine infection; intestine obstruction; intoxication; iodine deficiency; iron deficiency anemia; ischemic heart disease; kidney cancer; larynx cancer; latent tuberculosis; leishmaniasis; leprosy; leukemia; life expectancy; lip cancer; liver cancer; liver cirrhosis; low back pain; low income country; lower respiratory tract infection; lung cancer; lung sarcoidosis; lymphatic filariasis; macular degeneration; major clinical study; major depression; malaria; male; male infertility; malignant neoplasm; maternal death; maternal hemorrhage; maternal hypertension; measles; melanoma; meningitis; mesothelioma; middle income country; migraine; morbidity; motor neuron disease; mouth cancer; mouth malformation; mucocutaneous leishmaniasis; multiple myeloma; multiple sclerosis; myocarditis; nasopharynx cancer; neck pain; neglected disease; nematodiasis; neonatal encephalopathy; neural tube defect; newborn disease; newborn jaundice; newborn sepsis; nonhodgkin lymphoma; onchocerciasis; opiate addiction; osteoarthritis; otitis media; ovary cancer; pancreas cancer; pancreatitis; paralytic ileus; paratyphoid fever; Parkinson disease; pelvic organ prolapse; peptic ulcer; perinatal asphyxia; periodontal disease; peripheral occlusive artery disease; pertussis; physical violence; pneumococcal meningitis; pneumoconiosis; premature labor; premenstrual syndrome; priority journal; prostate cancer; prostate hypertrophy; protein calorie malnutrition; pruritus; psoriasis; pulmonary aspiration; pyoderma; rectum cancer; refraction error; retinol deficiency; rheumatic heart disease; rheumatoid arthritis; risk factor; scabies; schistosomiasis; schizophrenia; sickle cell trait; silicosis; skin leishmaniasis; spontaneous abortion; stomach cancer; sudden infant death syndrome; suffocation; syphilis; tension headache; terrorism; testis cancer; tetanus; thalassemia; thyroid cancer; trachea cancer; trachoma; traffic accident; trematodiasis; trichomoniasis; trichuriasis; tuberculosis; Turner syndrome; typhoid fever; upper respiratory tract infection; urinary tract infection; urticaria; uterine cervix cancer; uterus cancer; uterus myoma; uterus rupture; viral skin disease; visceral leishmaniasis; yellow fever; Zika fever; age distribution; communicable disease; demography; disabled person; global disease burden; global health; injury; life expectancy; middle aged; mortality; non communicable disease; quality adjusted life year; sex ratio; statistics and numerical data; trends; very elderly
7Adjusted Life Years
8Adult
9Adult; Age Distribution; Aged; Aged
10Adults
11africa
12Age
13Age Distribution
14Aged
15Aged, 80 and over
16Aldraðir
17Allmänmedicin
18Analysis
19asjc
20association
21atira
22australia
23Benchmarks
24Cause of Death
25Cause of Death - trends
26changes in health
27Charities
28Clinical Medicine
29Communicable Diseases
30Communicable Diseases - mortality
31Compression
32Coronary artery disease
33Decision making
34Demographics
35Disability
36Disabled Persons
37Disabled Persons - statistics & numerical data
38Disease
39Diseases
40dk
41Dánarmein
42environmental
43epidemiologic transition
44Epidemiology
45Family planning
46Faraldsfræði
47Fatlaðir
48Female
49Females
50Fertility
51Folkhälsovetenskap
52Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi
53Fullorðnir
54Félagshagfræði
55General & Internal
56General & Internal Medicine
57General Practice
58Global Burden of Disease
59Global Burden of Disease - statistics & numerical data
60Global Health
61Global Health - statistics & numerical data
62Global Health Metrics
63Global Helse
64Global Helse / Global Health
65global hälsa
66Halk Sağlığı
67health administration research
68Health and Welfare
69Health aspects
70Health care
71Health care science
72Health policy
73Health risks
74Health Sciences
75Health sciences: 800
76Health service
77Health service and health administration research: 806
78Health Services Administration
79healthy life expectancy
80Heart diseases
81Heilbrigðisstefna
82Heilsufar
83Helse
84Helse- og sykehusadministrasjon / Health Services Administration
85Helsefag
86Helsefag: 800
87Helsepolitikk
88Helsepolitikk / Health policy
89Helsetjeneste
90Helsetjeneste- og helseadministrasjonsforskning: 806
91hiv
92Humans
93Hälsa och välfärd
94Hälsovetenskap
95Hälsovetenskaper
96Injuries
97Journal Article
98Karlar
99Klinisk medicin
100Konur
101Life Expectancy
102Life Sciences & Biomedicine
103Life span
104Lífsgæði
105Lífslíkur
106Lýðheilsa
107Male
108Males
109Mathematical analysis
110Medical and Health Sciences
111Medical research
112Medicin och hälsovetenskap
113Medicine
114Medicine(all)
115Medicine, Experimental
116Medisinske fag
117Medisinske fag: 700
118Men
119Mental health
120Middle Aged
121Midical sciences
122Midical sciences: 700
123Morbidity
124Mortality
125Neonates
126Noncommunicable Diseases
127Noncommunicable Diseases - mortality
128occupational health
129og helseadministrasjonsforskning
130og sykehusadministrasjon
131Older people
132over
133People with disabilities
134plasmodium-falciparum
135Population
136prevalence
137Public Health
138Public Health, Global Health, Social Medicine and Epidemiology
139pubmedpublicationtype
140pure
141Quality
142Quality of life
143Quality-Adjusted Life Years
144researchoutput
145Residence Characteristics
146Residence Characteristics - statistics & numerical data
147Resource allocation
148Risk analysis
149Risk factors
150Science & Technology
151SDG 3 - Good Health and Well-being
152Sex
153Sex Distribution
154Sjúkdómar
155Social ecology
156Social Medicine
157socialmedicin och epidemiologi
158Sociodemographics
159statistics
160statistics & numerical data
161subjectarea
162Terveystiede
163therapy
164Trends
165Tölfræði
166VDP
167weights
168Women
169World health
170Wounds
171Wounds and Injuries - mortality
172Áverkar
173Þjóðir
issn
00140-6736
11474-547X
21474-547X
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startdate20170916
enddate20170916
creator
0Abate, Kalkidan Hassen
1Abu-Raddad, Laith J
2Adetokunboh, Olatunji
3Afshin, Ashkan
4Agrawal, Sutapa
5Alkaabi, Juma M
6Alla, François
7Alsowaidi, Shirina
8Ansha, Mustafa Geleto
9Antonio, Carl Abelardo T
10Asgedom, Solomon W
11Awasthi, Shally
12Bannick, Marlena S
13Barac, Aleksandra
14Baune, Bernhard T
15Bensenor, Isabela M
16Benson, Jennifer
17Berhane, Adugnaw
18Berhe, Derbew Fikadu
19Blyth, Fiona M
20Brainin, Michael
21Cahuana-Hurtado, Lucero
22Campos-Nonato, Ismael Ricardo
23Carpenter, David O
24Carter, Austin
25Colombara, Danny
26Dadi, Abel Fekadu
27Dalal, Koustuv
28Damasceno, Albertino
29Dhillon, Preet K
30Ebel, Beth E
31Franklin, Richard C
32Furtado, Joao M
33Geleijnse, Johanna M
34Ghajar, Alireza
35Gillum, Richard F
36Goel, Kashish
37Hamidi, Samer
38Haro, Josep Maria
39Harun, Kimani M
40Hendrie, Delia
41Htet, Aung Soe
42Karimi, Seyed M
43Kesavachandran, Chandrasekharan Nair
44Khubchandani, Jagdish
45Knudsen, Ann Kristin
46Kokubo, Yoshihiro
47Koyanagi, Ai
48Kumar, G Anil
49Liu, Shiwei
50Manhertz, Treh
51Martinez-Raga, Jose
52McGaughey, Madeline
53Misganaw, Awoke
54Mollenkopf, Sarah K
55Nagel, Gabriele
56Nasher, Jamal T
57Natarajan, Gopalakrishnan
58Nguyen, Minh
59Noubiap, Jean Jacques N
60Olagunju, Andrew Toyin
61Pacella, Rosana E
62Petri, William Arthur
63Phillips, Michael Robert
64Prasad, Narayan
65Purcell, Carrie
66Radfar, Amir
67Rahman, Mahfuzar
68Rajsic, Sasa
69Sanabria, Juan Ramon
70Santos, Itamar S
71Schöttker, Ben
72Seedat, Soraya
73Shiferaw, Mekonnen Sisay
74Shoman, Haitham
75Sibai, Abla Mehio
76Silveira, Dayane Gabriele Alves
77Singh, Jasvinder A
78Sinha, Dhirendra Narain
79Slepak, Erica Leigh
80Sobaih, Badr H A
81Sur, Patrick J
82Tabarés-Seisdedos, Rafael
83Tadakamadla, Santosh Kumar
84Tesfaye, Dawit Jember
85Thompson, Robert
86Tonelli, Marcello
87Tran, Bach Xuan
88Tuzcu, Emin Murat
89Tyrovolas, Stefanos
90Ukwaja, Kingsley Nnanna
91Undurraga, Eduardo A
92Updike, Rachel
93Veerman, Lennert J
94Vladimirov, Sergey K
95Vlassov, Vasiliy Victorovich
96Vollset, Stein Emil
97Woolf, Anthony D
98Zaki, Maysaa El Sayed
99Murray, Christopher J L
general
0Elsevier Ltd
1Elsevier B.V
2Elsevier Limited
3Elsevier
4Netherlands : Elsevier BV
5Lancet
6Karolinska institute, Dept Neurobiol, Div Family Med & Primary Care, Care Sci & Soc, Stockholm, Sweden; Dalarna Univ, Sch Hlth & Social Studies, Falun, Sweden
7Elsevier BV
8Inst Hlth Metr & Evaluat, Univ Washington, Seattle WA, USA
9Elsevier Science Inc
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creationdate20170916
titleGlobal, regional, and national disability-adjusted life-years (DALYs) for 333 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016
authorAbate, Kalkidan Hassen ; Abu-Raddad, Laith J ; Adetokunboh, Olatunji ; Afshin, Ashkan ; Agrawal, Sutapa ; Alkaabi, Juma M ; Alla, François ; Alsowaidi, Shirina ; Ansha, Mustafa Geleto ; Antonio, Carl Abelardo T ; Asgedom, Solomon W ; Awasthi, Shally ; Bannick, Marlena S ; Barac, Aleksandra ; Baune, Bernhard T ; Bensenor, Isabela M ; Benson, Jennifer ; Berhane, Adugnaw ; Berhe, Derbew Fikadu ; Blyth, Fiona M ; Brainin, Michael ; Cahuana-Hurtado, Lucero ; Campos-Nonato, Ismael Ricardo ; Carpenter, David O ; Carter, Austin ; Colombara, Danny ; Dadi, Abel Fekadu ; Dalal, Koustuv ; Damasceno, Albertino ; Dhillon, Preet K ; Ebel, Beth E ; Franklin, Richard C ; Furtado, Joao M ; Geleijnse, Johanna M ; Ghajar, Alireza ; Gillum, Richard F ; Goel, Kashish ; Hamidi, Samer ; Haro, Josep Maria ; Harun, Kimani M ; Hendrie, Delia ; Htet, Aung Soe ; Karimi, Seyed M ; Kesavachandran, Chandrasekharan Nair ; Khubchandani, Jagdish ; Knudsen, Ann Kristin ; Kokubo, Yoshihiro ; Koyanagi, Ai ; Kumar, G Anil ; Liu, Shiwei ; Manhertz, Treh ; Martinez-Raga, Jose ; McGaughey, Madeline ; Misganaw, Awoke ; Mollenkopf, Sarah K ; Nagel, Gabriele ; Nasher, Jamal T ; Natarajan, Gopalakrishnan ; Nguyen, Minh ; Noubiap, Jean Jacques N ; Olagunju, Andrew Toyin ; Pacella, Rosana E ; Petri, William Arthur ; Phillips, Michael Robert ; Prasad, Narayan ; Purcell, Carrie ; Radfar, Amir ; Rahman, Mahfuzar ; Rajsic, Sasa ; Sanabria, Juan Ramon ; Santos, Itamar S ; Schöttker, Ben ; Seedat, Soraya ; Shiferaw, Mekonnen Sisay ; Shoman, Haitham ; Sibai, Abla Mehio ; Silveira, Dayane Gabriele Alves ; Singh, Jasvinder A ; Sinha, Dhirendra Narain ; Slepak, Erica Leigh ; Sobaih, Badr H A ; Sur, Patrick J ; Tabarés-Seisdedos, Rafael ; Tadakamadla, Santosh Kumar ; Tesfaye, Dawit Jember ; Thompson, Robert ; Tonelli, Marcello ; Tran, Bach Xuan ; Tuzcu, Emin Murat ; Tyrovolas, Stefanos ; Ukwaja, Kingsley Nnanna ; Undurraga, Eduardo A ; Updike, Rachel ; Veerman, Lennert J ; Vladimirov, Sergey K ; Vlassov, Vasiliy Victorovich ; Vollset, Stein Emil ; Woolf, Anthony D ; Zaki, Maysaa El Sayed ; Murray, Christopher J L
facets
frbrtype5
frbrgroupidcdi_FETCH-LOGICAL-12878t-15020f0ac4f1bd733edaeeb9b5b78c6185e01394286c5c8fa548c9744eb8ba623
rsrctypearticles
prefilterarticles
languageeng
creationdate2017
topic
011 Medical And Health Sciences
13112 Neurosciences
23121 Internal medicine
33122 Cancers
43142 Public health care science
580 and over; Cause of Death; Communicable Diseases; Disabled Persons; Female; Global Burden of Disease; Global Health; Humans; Life Expectancy; Male; Middle Aged; Noncommunicable Diseases; Quality-Adjusted Life Years; Residence Characteristics; Sex Distribution; Wounds and Injuries
6abdominal wall hernia; abortion; accommodation disorder; acne vulgaris; acquired immune deficiency syndrome; acute glomerulonephritis; acute hepatitis A; acute hepatitis e; acute lymphoblastic leukemia; acute myeloid leukemia; adolescent; adult; African trypanosomiasis; aged; alcoholic cardiomyopathy; alcoholism; all cause mortality; alopecia areata; Alzheimer disease; amphetamine dependence; anorexia nervosa; anxiety disorder; aortic aneurysm; appendicitis; Article; asbestosis; ascariasis; Asperger syndrome; asthma; atrial fibrillation; attention deficit disorder; autism; automutilation; biliary tract cancer; biliary tract disease; bipolar disorder; bladder cancer; brain cancer; brain hemorrhage; brain ischemia; breast cancer; bronchus cancer; bulimia; cardiomyopathy; cataract; cause of death; cellulitis; cerebrovascular disease; Chagas disease; chickenpox; child; chlamydiasis; chronic kidney failure; chronic liver disease; chronic lymphatic leukemia; chronic myeloid leukemia; chronic obstructive lung disease; coal workers’ pneumoconiosis; cocaine dependence; colon cancer; conduct disorder; congenital disorder; cysticercosis; decubitus; dengue; dental caries; dermatitis; diabetes mellitus; diarrhea; diphtheria; disability-adjusted life year; disease course; diseases; Down syndrome; dracunculiasis; drowning; drug dependence; drug resistant tuberculosis; duodenitis; dysthymia; eating disorder; Ebola hemorrhagic fever; echinococcosis; ectopic pregnancy; encephalitis; endocarditis; endometriosis; epidemic meningitis; epilepsy; esophagus cancer; falling; female; female infertility; femoral hernia; food borne trematodiasis; foreign body; fungal skin disease; gallbladder cancer; gallbladder disease; gastritis; genital herpes; glaucoma; global disease burden; glucose 6 phosphate dehydrogenase deficiency; gonorrhea; gout; gross national product; groups by age; gunshot injury; haemophilus influenzae type b meningitis; health care policy; healthy life expectancy; hearing impairment; heart atrium flutter; hemolytic anemia; hepatitis; hepatitis B; hepatitis C; herpes zoster; Hodgkin disease; hookworm infection; human; Human immunodeficiency virus infection; ICD-10; ICD-9; inflammatory bowel disease; inguinal hernia; injury; intellectual impairment; interstitial lung disease; interstitial nephritis; intestine infection; intestine obstruction; intoxication; iodine deficiency; iron deficiency anemia; ischemic heart disease; kidney cancer; larynx cancer; latent tuberculosis; leishmaniasis; leprosy; leukemia; life expectancy; lip cancer; liver cancer; liver cirrhosis; low back pain; low income country; lower respiratory tract infection; lung cancer; lung sarcoidosis; lymphatic filariasis; macular degeneration; major clinical study; major depression; malaria; male; male infertility; malignant neoplasm; maternal death; maternal hemorrhage; maternal hypertension; measles; melanoma; meningitis; mesothelioma; middle income country; migraine; morbidity; motor neuron disease; mouth cancer; mouth malformation; mucocutaneous leishmaniasis; multiple myeloma; multiple sclerosis; myocarditis; nasopharynx cancer; neck pain; neglected disease; nematodiasis; neonatal encephalopathy; neural tube defect; newborn disease; newborn jaundice; newborn sepsis; nonhodgkin lymphoma; onchocerciasis; opiate addiction; osteoarthritis; otitis media; ovary cancer; pancreas cancer; pancreatitis; paralytic ileus; paratyphoid fever; Parkinson disease; pelvic organ prolapse; peptic ulcer; perinatal asphyxia; periodontal disease; peripheral occlusive artery disease; pertussis; physical violence; pneumococcal meningitis; pneumoconiosis; premature labor; premenstrual syndrome; priority journal; prostate cancer; prostate hypertrophy; protein calorie malnutrition; pruritus; psoriasis; pulmonary aspiration; pyoderma; rectum cancer; refraction error; retinol deficiency; rheumatic heart disease; rheumatoid arthritis; risk factor; scabies; schistosomiasis; schizophrenia; sickle cell trait; silicosis; skin leishmaniasis; spontaneous abortion; stomach cancer; sudden infant death syndrome; suffocation; syphilis; tension headache; terrorism; testis cancer; tetanus; thalassemia; thyroid cancer; trachea cancer; trachoma; traffic accident; trematodiasis; trichomoniasis; trichuriasis; tuberculosis; Turner syndrome; typhoid fever; upper respiratory tract infection; urinary tract infection; urticaria; uterine cervix cancer; uterus cancer; uterus myoma; uterus rupture; viral skin disease; visceral leishmaniasis; yellow fever; Zika fever; age distribution; communicable disease; demography; disabled person; global disease burden; global health; injury; life expectancy; middle aged; mortality; non communicable disease; quality adjusted life year; sex ratio; statistics and numerical data; trends; very elderly
7Adjusted Life Years
8Adult
9Adult; Age Distribution; Aged; Aged
10Adults
11africa
12Age
13Age Distribution
14Aged
15Aged, 80 and over
16Aldraðir
17Allmänmedicin
18Analysis
19asjc
20association
21atira
22australia
23Benchmarks
24Cause of Death
25Cause of Death - trends
26changes in health
27Charities
28Clinical Medicine
29Communicable Diseases
30Communicable Diseases - mortality
31Compression
32Coronary artery disease
33Decision making
34Demographics
35Disability
36Disabled Persons
37Disabled Persons - statistics & numerical data
38Disease
39Diseases
40dk
41Dánarmein
42environmental
43epidemiologic transition
44Epidemiology
45Family planning
46Faraldsfræði
47Fatlaðir
48Female
49Females
50Fertility
51Folkhälsovetenskap
52Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi
53Fullorðnir
54Félagshagfræði
55General & Internal
56General & Internal Medicine
57General Practice
58Global Burden of Disease
59Global Burden of Disease - statistics & numerical data
60Global Health
61Global Health - statistics & numerical data
62Global Health Metrics
63Global Helse
64Global Helse / Global Health
65global hälsa
66Halk Sağlığı
67health administration research
68Health and Welfare
69Health aspects
70Health care
71Health care science
72Health policy
73Health risks
74Health Sciences
75Health sciences: 800
76Health service
77Health service and health administration research: 806
78Health Services Administration
79healthy life expectancy
80Heart diseases
81Heilbrigðisstefna
82Heilsufar
83Helse
84Helse- og sykehusadministrasjon / Health Services Administration
85Helsefag
86Helsefag: 800
87Helsepolitikk
88Helsepolitikk / Health policy
89Helsetjeneste
90Helsetjeneste- og helseadministrasjonsforskning: 806
91hiv
92Humans
93Hälsa och välfärd
94Hälsovetenskap
95Hälsovetenskaper
96Injuries
97Journal Article
98Karlar
99Klinisk medicin
100Konur
101Life Expectancy
102Life Sciences & Biomedicine
103Life span
104Lífsgæði
105Lífslíkur
106Lýðheilsa
107Male
108Males
109Mathematical analysis
110Medical and Health Sciences
111Medical research
112Medicin och hälsovetenskap
113Medicine
114Medicine(all)
115Medicine, Experimental
116Medisinske fag
117Medisinske fag: 700
118Men
119Mental health
120Middle Aged
121Midical sciences
122Midical sciences: 700
123Morbidity
124Mortality
125Neonates
126Noncommunicable Diseases
127Noncommunicable Diseases - mortality
128occupational health
129og helseadministrasjonsforskning
130og sykehusadministrasjon
131Older people
132over
133People with disabilities
134plasmodium-falciparum
135Population
136prevalence
137Public Health
138Public Health, Global Health, Social Medicine and Epidemiology
139pubmedpublicationtype
140pure
141Quality
142Quality of life
143Quality-Adjusted Life Years
144researchoutput
145Residence Characteristics
146Residence Characteristics - statistics & numerical data
147Resource allocation
148Risk analysis
149Risk factors
150Science & Technology
151SDG 3 - Good Health and Well-being
152Sex
153Sex Distribution
154Sjúkdómar
155Social ecology
156Social Medicine
157socialmedicin och epidemiologi
158Sociodemographics
159statistics
160statistics & numerical data
161subjectarea
162Terveystiede
163therapy
164Trends
165Tölfræði
166VDP
167weights
168Women
169World health
170Wounds
171Wounds and Injuries - mortality
172Áverkar
173Þjóðir
toplevel
0peer_reviewed
1online_resources
creatorcontrib
0Abate, Kalkidan Hassen
1Abu-Raddad, Laith J
2Adetokunboh, Olatunji
3Afshin, Ashkan
4Agrawal, Sutapa
5Alkaabi, Juma M
6Alla, François
7Alsowaidi, Shirina
8Ansha, Mustafa Geleto
9Antonio, Carl Abelardo T
10Asgedom, Solomon W
11Awasthi, Shally
12Bannick, Marlena S
13Barac, Aleksandra
14Baune, Bernhard T
15Bensenor, Isabela M
16Benson, Jennifer
17Berhane, Adugnaw
18Berhe, Derbew Fikadu
19Blyth, Fiona M
20Brainin, Michael
21Cahuana-Hurtado, Lucero
22Campos-Nonato, Ismael Ricardo
23Carpenter, David O
24Carter, Austin
25Colombara, Danny
26Dadi, Abel Fekadu
27Dalal, Koustuv
28Damasceno, Albertino
29Dhillon, Preet K
30Ebel, Beth E
31Franklin, Richard C
32Furtado, Joao M
33Geleijnse, Johanna M
34Ghajar, Alireza
35Gillum, Richard F
36Goel, Kashish
37Hamidi, Samer
38Haro, Josep Maria
39Harun, Kimani M
40Hendrie, Delia
41Htet, Aung Soe
42Karimi, Seyed M
43Kesavachandran, Chandrasekharan Nair
44Khubchandani, Jagdish
45Knudsen, Ann Kristin
46Kokubo, Yoshihiro
47Koyanagi, Ai
48Kumar, G Anil
49Liu, Shiwei
50Manhertz, Treh
51Martinez-Raga, Jose
52McGaughey, Madeline
53Misganaw, Awoke
54Mollenkopf, Sarah K
55Nagel, Gabriele
56Nasher, Jamal T
57Natarajan, Gopalakrishnan
58Nguyen, Minh
59Noubiap, Jean Jacques N
60Olagunju, Andrew Toyin
61Pacella, Rosana E
62Petri, William Arthur
63Phillips, Michael Robert
64Prasad, Narayan
65Purcell, Carrie
66Radfar, Amir
67Rahman, Mahfuzar
68Rajsic, Sasa
69Sanabria, Juan Ramon
70Santos, Itamar S
71Schöttker, Ben
72Seedat, Soraya
73Shiferaw, Mekonnen Sisay
74Shoman, Haitham
75Sibai, Abla Mehio
76Silveira, Dayane Gabriele Alves
77Singh, Jasvinder A
78Sinha, Dhirendra Narain
79Slepak, Erica Leigh
80Sobaih, Badr H A
81Sur, Patrick J
82Tabarés-Seisdedos, Rafael
83Tadakamadla, Santosh Kumar
84Tesfaye, Dawit Jember
85Thompson, Robert
86Tonelli, Marcello
87Tran, Bach Xuan
88Tuzcu, Emin Murat
89Tyrovolas, Stefanos
90Ukwaja, Kingsley Nnanna
91Undurraga, Eduardo A
92Updike, Rachel
93Veerman, Lennert J
94Vladimirov, Sergey K
95Vlassov, Vasiliy Victorovich
96Vollset, Stein Emil
97Woolf, Anthony D
98Zaki, Maysaa El Sayed
99Murray, Christopher J L
100GBD 2016 DALYs and HALE Collaborators
101Sahlgrenska akademin
102Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa, enheten för hälsometri
103Institute of Medicine, Department of Public Health and Community Medicine, Health Metrics
104Göteborgs universitet
105Gothenburg University
106Sahlgrenska Academy
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36ProQuest Natural Science Collection
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38Hospital Premium Collection (Alumni Edition)
39ProQuest Central (Alumni) (purchase pre-March 2016)
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75ProQuest One Academic Eastern Edition
76ProQuest One Academic
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83OpenAIRE
84PubMed Central (Full Participant titles)
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0Abate, Kalkidan Hassen
1Abu-Raddad, Laith J
2Adetokunboh, Olatunji
3Afshin, Ashkan
4Agrawal, Sutapa
5Alkaabi, Juma M
6Alla, François
7Alsowaidi, Shirina
8Ansha, Mustafa Geleto
9Antonio, Carl Abelardo T
10Asgedom, Solomon W
11Awasthi, Shally
12Bannick, Marlena S
13Barac, Aleksandra
14Baune, Bernhard T
15Bensenor, Isabela M
16Benson, Jennifer
17Berhane, Adugnaw
18Berhe, Derbew Fikadu
19Blyth, Fiona M
20Brainin, Michael
21Cahuana-Hurtado, Lucero
22Campos-Nonato, Ismael Ricardo
23Carpenter, David O
24Carter, Austin
25Colombara, Danny
26Dadi, Abel Fekadu
27Dalal, Koustuv
28Damasceno, Albertino
29Dhillon, Preet K
30Ebel, Beth E
31Franklin, Richard C
32Furtado, Joao M
33Geleijnse, Johanna M
34Ghajar, Alireza
35Gillum, Richard F
36Goel, Kashish
37Hamidi, Samer
38Haro, Josep Maria
39Harun, Kimani M
40Hendrie, Delia
41Htet, Aung Soe
42Karimi, Seyed M
43Kesavachandran, Chandrasekharan Nair
44Khubchandani, Jagdish
45Knudsen, Ann Kristin
46Kokubo, Yoshihiro
47Koyanagi, Ai
48Kumar, G Anil
49Liu, Shiwei
50Manhertz, Treh
51Martinez-Raga, Jose
52McGaughey, Madeline
53Misganaw, Awoke
54Mollenkopf, Sarah K
55Nagel, Gabriele
56Nasher, Jamal T
57Natarajan, Gopalakrishnan
58Nguyen, Minh
59Noubiap, Jean Jacques N
60Olagunju, Andrew Toyin
61Pacella, Rosana E
62Petri, William Arthur
63Phillips, Michael Robert
64Prasad, Narayan
65Purcell, Carrie
66Radfar, Amir
67Rahman, Mahfuzar
68Rajsic, Sasa
69Sanabria, Juan Ramon
70Santos, Itamar S
71Schöttker, Ben
72Seedat, Soraya
73Shiferaw, Mekonnen Sisay
74Shoman, Haitham
75Sibai, Abla Mehio
76Silveira, Dayane Gabriele Alves
77Singh, Jasvinder A
78Sinha, Dhirendra Narain
79Slepak, Erica Leigh
80Sobaih, Badr H A
81Sur, Patrick J
82Tabarés-Seisdedos, Rafael
83Tadakamadla, Santosh Kumar
84Tesfaye, Dawit Jember
85Thompson, Robert
86Tonelli, Marcello
87Tran, Bach Xuan
88Tuzcu, Emin Murat
89Tyrovolas, Stefanos
90Ukwaja, Kingsley Nnanna
91Undurraga, Eduardo A
92Updike, Rachel
93Veerman, Lennert J
94Vladimirov, Sergey K
95Vlassov, Vasiliy Victorovich
96Vollset, Stein Emil
97Woolf, Anthony D
98Zaki, Maysaa El Sayed
99Murray, Christopher J L
aucorp
0GBD 2016 DALYs and HALE Collaborators
1Sahlgrenska akademin
2Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa, enheten för hälsometri
3Institute of Medicine, Department of Public Health and Community Medicine, Health Metrics
4Göteborgs universitet
5Gothenburg University
6Sahlgrenska Academy
formatjournal
genrearticle
ristypeJOUR
atitleGlobal, regional, and national disability-adjusted life-years (DALYs) for 333 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016
jtitleLancet
addtitleLancet
date2017-09-16
risdate2017
volume390
issue10100
spage1260
epage1344
pages1260-1344
issn
00140-6736
11474-547X
eissn1474-547X
notes
0The Lancet
1Collaborators listed at the end of the Article
abstractMeasurement of changes in health across locations is useful to compare and contrast changing epidemiological patterns against health system performance and identify specific needs for resource allocation in research, policy development, and programme decision making. Using the Global Burden of Diseases, Injuries, and Risk Factors Study 2016, we drew from two widely used summary measures to monitor such changes in population health: disability-adjusted life-years (DALYs) and healthy life expectancy (HALE). We used these measures to track trends and benchmark progress compared with expected trends on the basis of the Socio-demographic Index (SDI). We used results from the Global Burden of Diseases, Injuries, and Risk Factors Study 2016 for all-cause mortality, cause-specific mortality, and non-fatal disease burden to derive HALE and DALYs by sex for 195 countries and territories from 1990 to 2016. We calculated DALYs by summing years of life lost and years of life lived with disability for each location, age group, sex, and year. We estimated HALE using age-specific death rates and years of life lived with disability per capita. We explored how DALYs and HALE differed from expected trends when compared with the SDI: the geometric mean of income per person, educational attainment in the population older than age 15 years, and total fertility rate. The highest globally observed HALE at birth for both women and men was in Singapore, at 75·2 years (95% uncertainty interval 71·9–78·6) for females and 72·0 years (68·8–75·1) for males. The lowest for females was in the Central African Republic (45·6 years [42·0–49·5]) and for males was in Lesotho (41·5 years [39·0–44·0]). From 1990 to 2016, global HALE increased by an average of 6·24 years (5·97–6·48) for both sexes combined. Global HALE increased by 6·04 years (5·74–6·27) for males and 6·49 years (6·08–6·77) for females, whereas HALE at age 65 years increased by 1·78 years (1·61–1·93) for males and 1·96 years (1·69–2·13) for females. Total global DALYs remained largely unchanged from 1990 to 2016 (–2·3% [–5·9 to 0·9]), with decreases in communicable, maternal, neonatal, and nutritional (CMNN) disease DALYs offset by increased DALYs due to non-communicable diseases (NCDs). The exemplars, calculated as the five lowest ratios of observed to expected age-standardised DALY rates in 2016, were Nicaragua, Costa Rica, the Maldives, Peru, and Israel. The leading three causes of DALYs globally were ischaemic heart disease, cerebrovascular disease, and lower respiratory infections, comprising 16·1% of all DALYs. Total DALYs and age-standardised DALY rates due to most CMNN causes decreased from 1990 to 2016. Conversely, the total DALY burden rose for most NCDs; however, age-standardised DALY rates due to NCDs declined globally. At a global level, DALYs and HALE continue to show improvements. At the same time, we observe that many populations are facing growing functional health loss. Rising SDI was associated with increases in cumulative years of life lived with disability and decreases in CMNN DALYs offset by increased NCD DALYs. Relative compression of morbidity highlights the importance of continued health interventions, which has changed in most locations in pace with the gross domestic product per person, education, and family planning. The analysis of DALYs and HALE and their relationship to SDI represents a robust framework with which to benchmark location-specific health performance. Country-specific drivers of disease burden, particularly for causes with higher-than-expected DALYs, should inform health policies, health system improvement initiatives, targeted prevention efforts, and development assistance for health, including financial and research investments for all countries, regardless of their level of sociodemographic development. The presence of countries that substantially outperform others suggests the need for increased scrutiny for proven examples of best practices, which can help to extend gains, whereas the presence of underperforming countries suggests the need for devotion of extra attention to health systems that need more robust support. Bill & Melinda Gates Foundation.
copEngland
pubElsevier Ltd
pmid28919118
doi10.1016/S0140-6736(17)32130-X
oafree_for_read