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连续性血液净化治疗急性有机磷农药中毒的疗效观察 - Observation of the curative effects of continuous blood purification in the treatment of acute organophosphorus pesticide poisoning

目的分析研究连续性血液净化对急性有机磷农药中毒患者的治疗效果及安全性。方法选择2008年1月~2013年9月我院急性有机磷农药中毒患者共70例为临床研究对象,将患者分为两组。对照组患者给予临床常规治疗,实验组患者给予HP+CVVH序贯治疗,观察比较两组患者的治疗过程中发生低氧血症、呼吸衰竭、脏器损伤及死亡率和患者血清SOD等指标。结果实验组患者发生低氧血症、呼吸衰竭、脏器损伤低于对照组患者,死亡率低于对照组患者,差异有统计学意义(P〈0.05)。实验组患者治疗后血清hs—CRP水平更低,胆碱酯酶活性优于对照组患者,差异有统计学意义(P〈0.05)。结论使用连续性血液净化对急性有机磷农药中毒具有... Full description

Journal Title: 中国医药科学 - China medicine and pharmacy 2014, Vol.4(05), pp.142-144
Main Author: 庞荣锋
Other Authors: 黄永鹏 , 范小龙 , 马俊 , 余庆华 , 伍增龙 , PANG Rongfeng HUANG Yongpeng FAN Xiaolong MA Jun YU Qinghua WU Zenglong
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ID: ISSN: 2095-0616
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title: 连续性血液净化治疗急性有机磷农药中毒的疗效观察 - Observation of the curative effects of continuous blood purification in the treatment of acute organophosphorus pesticide poisoning
format: Article
creator:
  • 庞荣锋
  • 黄永鹏
  • 范小龙
  • 马俊
  • 余庆华
  • 伍增龙
  • PANG Rongfeng HUANG Yongpeng FAN Xiaolong MA Jun YU Qinghua WU Zenglong
subjects:
  • 急性有机磷农药中毒
  • 血液净化
  • 连续性
  • 农药中毒
  • Acute Organophosphorus Pesticide Poisoning
  • Blood Purification
  • Continuous
  • Pesticide Poisoning
ispartof: 中国医药科学 - China medicine and pharmacy, 2014, Vol.4(05), pp.142-144
description: 目的分析研究连续性血液净化对急性有机磷农药中毒患者的治疗效果及安全性。方法选择2008年1月~2013年9月我院急性有机磷农药中毒患者共70例为临床研究对象,将患者分为两组。对照组患者给予临床常规治疗,实验组患者给予HP+CVVH序贯治疗,观察比较两组患者的治疗过程中发生低氧血症、呼吸衰竭、脏器损伤及死亡率和患者血清SOD等指标。结果实验组患者发生低氧血症、呼吸衰竭、脏器损伤低于对照组患者,死亡率低于对照组患者,差异有统计学意义(P〈0.05)。实验组患者治疗后血清hs—CRP水平更低,胆碱酯酶活性优于对照组患者,差异有统计学意义(P〈0.05)。结论使用连续性血液净化对急性有机磷农药中毒具有较好的效果,可以有效地降低患者的死亡率,减轻患者的损伤。
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source: 维普数据 (Chongqing VIP Information Co.)
identifier: ISSN: 2095-0616
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  • 2095-0616
  • 20950616
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title连续性血液净化治疗急性有机磷农药中毒的疗效观察 - Observation of the curative effects of continuous blood purification in the treatment of acute organophosphorus pesticide poisoning
creator庞荣锋 ; 黄永鹏 ; 范小龙 ; 马俊 ; 余庆华 ; 伍增龙 ; PANG Rongfeng HUANG Yongpeng FAN Xiaolong MA Jun YU Qinghua WU Zenglong
ispartof中国医药科学 - China medicine and pharmacy, 2014, Vol.4(05), pp.142-144
identifierISSN: 2095-0616
subject急性有机磷农药中毒 ; 血液净化 ; 连续性 ; 农药中毒 ; Acute Organophosphorus Pesticide Poisoning;Blood Purification;Continuous;Pesticide Poisoning
description
0目的分析研究连续性血液净化对急性有机磷农药中毒患者的治疗效果及安全性。方法选择2008年1月~2013年9月我院急性有机磷农药中毒患者共70例为临床研究对象,将患者分为两组。对照组患者给予临床常规治疗,实验组患者给予HP+CVVH序贯治疗,观察比较两组患者的治疗过程中发生低氧血症、呼吸衰竭、脏器损伤及死亡率和患者血清SOD等指标。结果实验组患者发生低氧血症、呼吸衰竭、脏器损伤低于对照组患者,死亡率低于对照组患者,差异有统计学意义(P〈0.05)。实验组患者治疗后血清hs—CRP水平更低,胆碱酯酶活性优于对照组患者,差异有统计学意义(P〈0.05)。结论使用连续性血液净化对急性有机磷农药中毒具有较好的效果,可以有效地降低患者的死亡率,减轻患者的损伤。
1Objective To analyze and explore the curative effects and safety of continuous blood purification for patients with acute organophosphorus pesticide poisoning. Methods 70 patients with acute organophosphorus pesticide poisoning who were admitted to our hospital from January 2008 to September 2013 were selected as subjects and assigned to two groups. The control group received a regular clinical treatment, while the experimental group received a sequential therapy of HP and CVVH. Different indices such as hypoxemia, respiratory failure, organ injuries, mortality rate and patients' serum SOD between the two groups were observed and compared during treatments. Results Incidences of hypoxemia, respiratory failure and organ injuries in the experimental group were lower than those in the control group, and the mortality rate was lower than that in the control group, the differences were statistically significant(P 〈 0.05). The level of serum hs-CRP in the experimental group after the treatment became lower and the cholinesterase activity was better than that in the control group, the differences were statistically significant(P 〈 0.05). Conclusion Continuous blood purification in the treatment of acute organophosphorus pesticide poisoning has favorable effects of reducing patients' mortality and alleviating patient's injuries.
relation作者单位: 广东省佛山市高明区人民医院重症医学科,广东佛山528500
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7广东省佛山市高明区人民医院重症医学科,广东佛山528500
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0连续性血液净化治疗急性有机磷农药中毒的疗效观察
1Observation of the curative effects of continuous blood purification in the treatment of acute organophosphorus pesticide poisoning
description
0目的分析研究连续性血液净化对急性有机磷农药中毒患者的治疗效果及安全性。方法选择2008年1月~2013年9月我院急性有机磷农药中毒患者共70例为临床研究对象,将患者分为两组。对照组患者给予临床常规治疗,实验组患者给予HP+CVVH序贯治疗,观察比较两组患者的治疗过程中发生低氧血症、呼吸衰竭、脏器损伤及死亡率和患者血清SOD等指标。结果实验组患者发生低氧血症、呼吸衰竭、脏器损伤低于对照组患者,死亡率低于对照组患者,差异有统计学意义(P〈0.05)。实验组患者治疗后血清hs—CRP水平更低,胆碱酯酶活性优于对照组患者,差异有统计学意义(P〈0.05)。结论使用连续性血液净化对急性有机磷农药中毒具有较好的效果,可以有效地降低患者的死亡率,减轻患者的损伤。
1Objective To analyze and explore the curative effects and safety of continuous blood purification for patients with acute organophosphorus pesticide poisoning. Methods 70 patients with acute organophosphorus pesticide poisoning who were admitted to our hospital from January 2008 to September 2013 were selected as subjects and assigned to two groups. The control group received a regular clinical treatment, while the experimental group received a sequential therapy of HP and CVVH. Different indices such as hypoxemia, respiratory failure, organ injuries, mortality rate and patients' serum SOD between the two groups were observed and compared during treatments. Results Incidences of hypoxemia, respiratory failure and organ injuries in the experimental group were lower than those in the control group, and the mortality rate was lower than that in the control group, the differences were statistically significant(P 〈 0.05). The level of serum hs-CRP in the experimental group after the treatment became lower and the cholinesterase activity was better than that in the control group, the differences were statistically significant(P 〈 0.05). Conclusion Continuous blood purification in the treatment of acute organophosphorus pesticide poisoning has favorable effects of reducing patients' mortality and alleviating patient's injuries.
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0急性有机磷农药中毒
1血液净化
2连续性
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4Acute Organophosphorus Pesticide Poisoning
5Blood Purification
6Continuous
7Pesticide Poisoning
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title连续性血液净化治疗急性有机磷农药中毒的疗效观察 - Observation of the curative effects of continuous blood purification in the treatment of acute organophosphorus pesticide poisoning
author庞荣锋 ; 黄永鹏 ; 范小龙 ; 马俊 ; 余庆华 ; 伍增龙 ; PANG Rongfeng HUANG Yongpeng FAN Xiaolong MA Jun YU Qinghua WU Zenglong
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atitle连续性血液净化治疗急性有机磷农药中毒的疗效观察 - Observation of the curative effects of continuous blood purification in the treatment of acute organophosphorus pesticide poisoning
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0目的分析研究连续性血液净化对急性有机磷农药中毒患者的治疗效果及安全性。方法选择2008年1月~2013年9月我院急性有机磷农药中毒患者共70例为临床研究对象,将患者分为两组。对照组患者给予临床常规治疗,实验组患者给予HP+CVVH序贯治疗,观察比较两组患者的治疗过程中发生低氧血症、呼吸衰竭、脏器损伤及死亡率和患者血清SOD等指标。结果实验组患者发生低氧血症、呼吸衰竭、脏器损伤低于对照组患者,死亡率低于对照组患者,差异有统计学意义(P〈0.05)。实验组患者治疗后血清hs—CRP水平更低,胆碱酯酶活性优于对照组患者,差异有统计学意义(P〈0.05)。结论使用连续性血液净化对急性有机磷农药中毒具有较好的效果,可以有效地降低患者的死亡率,减轻患者的损伤。
1Objective To analyze and explore the curative effects and safety of continuous blood purification for patients with acute organophosphorus pesticide poisoning. Methods 70 patients with acute organophosphorus pesticide poisoning who were admitted to our hospital from January 2008 to September 2013 were selected as subjects and assigned to two groups. The control group received a regular clinical treatment, while the experimental group received a sequential therapy of HP and CVVH. Different indices such as hypoxemia, respiratory failure, organ injuries, mortality rate and patients' serum SOD between the two groups were observed and compared during treatments. Results Incidences of hypoxemia, respiratory failure and organ injuries in the experimental group were lower than those in the control group, and the mortality rate was lower than that in the control group, the differences were statistically significant(P 〈 0.05). The level of serum hs-CRP in the experimental group after the treatment became lower and the cholinesterase activity was better than that in the control group, the differences were statistically significant(P 〈 0.05). Conclusion Continuous blood purification in the treatment of acute organophosphorus pesticide poisoning has favorable effects of reducing patients' mortality and alleviating patient's injuries.
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