schliessen

Filtern

 

Bibliotheken

Estimates of global, regional, and national incidence, prevalence, and mortality of HIV, 1980-2015: the Global Burden of Disease Study 2015.

BACKGROUND: Timely assessment of the burden of HIV/AIDS is essential for policy setting and programme evaluation. In this report from the Global Burden of Disease Study 2015 (GBD 2015), we provide national estimates of levels and trends of HIV/AIDS incidence, prevalence, coverage of antiretroviral t... Full description

Journal Title: The lancet. HIV 2016, Vol. 3(8), pp. e361-e387
Main Author: Wang, Haidong
Other Authors: Wolock, Tim M , Carter, Austin , Nguyen, Grant , Kyu, Hmwe Hmwe , Gakidou, Emmanuela , Hay, Simon I , Mills, Edward J , Trickey, Adam , Msemburi, William , Coates, Matthew M , Mooney, Meghan D , Fraser, Maya S , Sligar, Amber , Salomon, Joshua , Larson, Heidi J , Friedman, Joseph , Abajobir, Amanuel Alemu , Abate, Kalkidan Hassen , Abbas, Kaja M , Razek, Mohamed Magdy Abd El , Abd-Allah, Foad , Abdulle, Abdishakur M , Abera, Semaw Ferede , Abubakar, Ibrahim , Abu-Raddad, Laith J , Abu-Rmeileh, Niveen M E , Abyu, Gebre Yitayih , Adebiyi, Akindele Olupelumi , Adedeji, Isaac Akinkunmi , Adelekan, Ademola Lukman , Adofo, Koranteng , Adou, Arsène Kouablan , Ajala, Oluremi N , Akinyemiju, Tomi F , Akseer, Nadia , Lami, Faris Hasan Al , Al-Aly, Ziyad , Alam, Khurshid , Alam, Noore K M , Alasfoor, Deena , Aldhahri, Saleh Fahed S , Aldridge, Robert William , Alegretti, Miguel Angel , Aleman, Alicia V , Alemu, Zewdie Aderaw , Alfonso-Cristancho, Rafael , Ali, Raghib , Alkerwi, Ala'a , Alla, François , Mohammad, Rajaa , Al-Raddadi, Salem , Alsharif, Ubai , Alvarez, Elena , Alvis-Guzman, Nelson , Amare, Azmeraw T , Amberbir, Alemayehu , Amegah, Adeladza Kofi , Ammar, Walid , Amrock, Stephen Marc , Antonio, Carl Abelardo T , Anwari, Palwasha , Ärnlöv, Johan , Artaman, Al , Asayesh, Hamid , Asghar, Rana Jawad , Assadi, Reza , Atique, Suleman , Atkins, Lydia S , Avokpaho, Euripide Frinel G Arthur , Awasthi, Ashish , Quintanilla, Beatriz Paulina Ayala , Bacha, Umar , Badawi, Alaa , Barac, Aleksandra , Bärnighausen, Till , Basu, Arindam , Bayou, Tigist Assefa , Bayou, Yibeltal Tebekaw , Bazargan-Hejazi, Shahrzad , Beardsley, Justin , Bedi, Neeraj , Bennett, Derrick A , Bensenor, Isabela M , Betsu, Balem Demtsu , Beyene, Addisu Shunu , Bhatia, Eesh , Bhutta, Zulfiqar A , Biadgilign, Sibhatu , Bikbov, Boris , Birlik, Sait Mentes , Bisanzio, Donal , Brainin, Michael , Brazinova, Alexandra , Breitborde, Nicholas J K , Brown, Alexandria , Burch, Michael , Butt, Zahid A , Campuzano, Julio Cesar , Cárdenas, Rosario , Carrero, Juan Jesus , Castañeda-Orjuela, Carlos A , Rivas, Jacqueline Castillo , Catalá-López, Ferrán , Chang, Hsing-Yi , Chang, Jung-Chen , Chavan, Laxmikant , Chen, Wanqing , Chiang, Peggy Pei-Chia , Chibalabala, Mirriam , Chisumpa, Vesper Hichilombwe , Choi, Jee-Young Jasmine , Christopher, Devasahayam Jesudas , Ciobanu, Liliana G , Cooper, Cyrus , Dahiru, Tukur , Damtew, Solomon Abreha , Dandona, Lalit , Dandona, Rakhi , das Neves, José , de Jager, Pieter , De Leo, Diego , Degenhardt, Louisa , Dellavalle, Robert P , Deribe, Kebede , Deribew, Amare , Des Jarlais, Don C , Dharmaratne, Samath D , Ding, Eric L , Doshi, Pratik Pinal , Driscoll, Tim R , Dubey, Manisha , Elshrek, Yousef Mohamed , Elyazar, Iqbal , Endries, Aman Yesuf , Ermakov, Sergey Petrovich , Eshrati, Babak , Esteghamati, Alireza , Faghmous, Imad D A , Farinha, Carla Sofia E Sa , Faro, Andre , Farvid, Maryam S , Farzadfar, Farshad , Fereshtehnejad, Seyed-Mohammad , Fernandes, Joao C , Fischer, Florian , Fitchett, Joseph Robert Ander , Foigt, Nataliya , Fullman, Nancy , Fürst, Thomas , Gankpé, Fortuné Gbètoho , Gebre, Teshome , Gebremedhin, Amanuel Tesfay , Gebru, Alemseged Aregay , Geleijnse, Johanna M , Gessner, Bradford D , Gething, Peter W , Ghiwot, Tsegaye Tewelde , Giroud, Maurice , Gishu, Melkamu Dedefo , Glaser, Elizabeth , Goenka, Shifalika , Goodridge, Amador , Gopalani, Sameer Vali , Goto, Atsushi , Gugnani, Harish Chander , Guimaraes, Mark D C , Gupta, Rahul , Gupta, Rajeev , Gupta, Vipin , Haagsma, Juanita , Hafezi-Nejad, Nima , Hagan, Holly , Hailu, Gessessew Bugssa , Hamadeh, Randah Ribhi , Hamidi, Samer , Hammami, Mouhanad , Hankey, Graeme J , Hao, Yuantao , Harb, Hilda L , Harikrishnan, Sivadasanpillai , Haro, Josep Maria , Harun, Kimani M , Havmoeller, Rasmus , Hedayati, Mohammad T , Heredia-Pi, Ileana Beatriz , Hoek, Hans W , Horino, Masako , Horita, Nobuyuki , Hosgood, H Dean , Hoy, Damian G , Hsairi, Mohamed , Hu, Guoqing , Huang, Hsiang , Huang, John J , Iburg, Kim Moesgaard , Idrisov, Bulat T , Innos, Kaire , Iyer, Veena J , Jacobsen, Kathryn H , Jahanmehr, Nader , Jakovljevic, Mihajlo B , Javanbakht, Mehdi , Jayatilleke, Achala Upendra , Jeemon, Panniyammakal , Jha, Vivekanand , Jiang, Guohong , Jiang, Ying , Jibat, Tariku , Jonas, Jost B , Kabir, Zubair , Kamal, Ritul , Kan, Haidong , Karch, André , Karema, Corine Kakizi , Karletsos, Dimitris , Kasaeian, Amir , Kaul, Anil , Kawakami, Norito , Kayibanda, Jeanne Françoise , Keiyoro, Peter Njenga , Kemp, Andrew Haddon , Kengne, Andre Pascal , Kesavachandran, Chandrasekharan Nair , Khader, Yousef Saleh , Khalil, Ibrahim , Khan, Abdur Rahman , Khan, Ejaz Ahmad , Khang, Young-Ho , Khubchandani, Jagdish , Kim, Yun Jin , Kinfu, Yohannes , Kivipelto, Miia , Kokubo, Yoshihiro , Kosen, Soewarta , Koul, Parvaiz A , Koyanagi, Ai , Defo, Barthelemy Kuate , Bicer, Burcu Kucuk , Kulkarni, Veena S , Kumar, G Anil , Lal, Dharmesh Kumar , Lam, Hilton , Lam, Jennifer O , Langan, Sinead M , Lansingh, Van C , Larsson, Anders , Leigh, James , Leung, Ricky , Li, Yongmei
Format: Electronic Article Electronic Article
Language: English
Subjects:
ID: ISSN: 2352-3018 ; DOI: 10.1016/S2352-3018(16)30087-X
Link: http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-299966
Zum Text:
SendSend as email Add to Book BagAdd to Book Bag
Staff View
recordid: divauu-299966
title: Estimates of global, regional, and national incidence, prevalence, and mortality of HIV, 1980-2015: the Global Burden of Disease Study 2015.
format: Article
creator:
  • Wang, Haidong
  • Wolock, Tim M
  • Carter, Austin
  • Nguyen, Grant
  • Kyu, Hmwe Hmwe
  • Gakidou, Emmanuela
  • Hay, Simon I
  • Mills, Edward J
  • Trickey, Adam
  • Msemburi, William
  • Coates, Matthew M
  • Mooney, Meghan D
  • Fraser, Maya S
  • Sligar, Amber
  • Salomon, Joshua
  • Larson, Heidi J
  • Friedman, Joseph
  • Abajobir, Amanuel Alemu
  • Abate, Kalkidan Hassen
  • Abbas, Kaja M
  • Razek, Mohamed Magdy Abd El
  • Abd-Allah, Foad
  • Abdulle, Abdishakur M
  • Abera, Semaw Ferede
  • Abubakar, Ibrahim
  • Abu-Raddad, Laith J
  • Abu-Rmeileh, Niveen M E
  • Abyu, Gebre Yitayih
  • Adebiyi, Akindele Olupelumi
  • Adedeji, Isaac Akinkunmi
  • Adelekan, Ademola Lukman
  • Adofo, Koranteng
  • Adou, Arsène Kouablan
  • Ajala, Oluremi N
  • Akinyemiju, Tomi F
  • Akseer, Nadia
  • Lami, Faris Hasan Al
  • Al-Aly, Ziyad
  • Alam, Khurshid
  • Alam, Noore K M
  • Alasfoor, Deena
  • Aldhahri, Saleh Fahed S
  • Aldridge, Robert William
  • Alegretti, Miguel Angel
  • Aleman, Alicia V
  • Alemu, Zewdie Aderaw
  • Alfonso-Cristancho, Rafael
  • Ali, Raghib
  • Alkerwi, Ala'a
  • Alla, François
  • Mohammad, Rajaa
  • Al-Raddadi, Salem
  • Alsharif, Ubai
  • Alvarez, Elena
  • Alvis-Guzman, Nelson
  • Amare, Azmeraw T
  • Amberbir, Alemayehu
  • Amegah, Adeladza Kofi
  • Ammar, Walid
  • Amrock, Stephen Marc
  • Antonio, Carl Abelardo T
  • Anwari, Palwasha
  • Ärnlöv, Johan
  • Artaman, Al
  • Asayesh, Hamid
  • Asghar, Rana Jawad
  • Assadi, Reza
  • Atique, Suleman
  • Atkins, Lydia S
  • Avokpaho, Euripide Frinel G Arthur
  • Awasthi, Ashish
  • Quintanilla, Beatriz Paulina Ayala
  • Bacha, Umar
  • Badawi, Alaa
  • Barac, Aleksandra
  • Bärnighausen, Till
  • Basu, Arindam
  • Bayou, Tigist Assefa
  • Bayou, Yibeltal Tebekaw
  • Bazargan-Hejazi, Shahrzad
  • Beardsley, Justin
  • Bedi, Neeraj
  • Bennett, Derrick A
  • Bensenor, Isabela M
  • Betsu, Balem Demtsu
  • Beyene, Addisu Shunu
  • Bhatia, Eesh
  • Bhutta, Zulfiqar A
  • Biadgilign, Sibhatu
  • Bikbov, Boris
  • Birlik, Sait Mentes
  • Bisanzio, Donal
  • Brainin, Michael
  • Brazinova, Alexandra
  • Breitborde, Nicholas J K
  • Brown, Alexandria
  • Burch, Michael
  • Butt, Zahid A
  • Campuzano, Julio Cesar
  • Cárdenas, Rosario
  • Carrero, Juan Jesus
  • Castañeda-Orjuela, Carlos A
  • Rivas, Jacqueline Castillo
  • Catalá-López, Ferrán
  • Chang, Hsing-Yi
  • Chang, Jung-Chen
  • Chavan, Laxmikant
  • Chen, Wanqing
  • Chiang, Peggy Pei-Chia
  • Chibalabala, Mirriam
  • Chisumpa, Vesper Hichilombwe
  • Choi, Jee-Young Jasmine
  • Christopher, Devasahayam Jesudas
  • Ciobanu, Liliana G
  • Cooper, Cyrus
  • Dahiru, Tukur
  • Damtew, Solomon Abreha
  • Dandona, Lalit
  • Dandona, Rakhi
  • das Neves, José
  • de Jager, Pieter
  • De Leo, Diego
  • Degenhardt, Louisa
  • Dellavalle, Robert P
  • Deribe, Kebede
  • Deribew, Amare
  • Des Jarlais, Don C
  • Dharmaratne, Samath D
  • Ding, Eric L
  • Doshi, Pratik Pinal
  • Driscoll, Tim R
  • Dubey, Manisha
  • Elshrek, Yousef Mohamed
  • Elyazar, Iqbal
  • Endries, Aman Yesuf
  • Ermakov, Sergey Petrovich
  • Eshrati, Babak
  • Esteghamati, Alireza
  • Faghmous, Imad D A
  • Farinha, Carla Sofia E Sa
  • Faro, Andre
  • Farvid, Maryam S
  • Farzadfar, Farshad
  • Fereshtehnejad, Seyed-Mohammad
  • Fernandes, Joao C
  • Fischer, Florian
  • Fitchett, Joseph Robert Ander
  • Foigt, Nataliya
  • Fullman, Nancy
  • Fürst, Thomas
  • Gankpé, Fortuné Gbètoho
  • Gebre, Teshome
  • Gebremedhin, Amanuel Tesfay
  • Gebru, Alemseged Aregay
  • Geleijnse, Johanna M
  • Gessner, Bradford D
  • Gething, Peter W
  • Ghiwot, Tsegaye Tewelde
  • Giroud, Maurice
  • Gishu, Melkamu Dedefo
  • Glaser, Elizabeth
  • Goenka, Shifalika
  • Goodridge, Amador
  • Gopalani, Sameer Vali
  • Goto, Atsushi
  • Gugnani, Harish Chander
  • Guimaraes, Mark D C
  • Gupta, Rahul
  • Gupta, Rajeev
  • Gupta, Vipin
  • Haagsma, Juanita
  • Hafezi-Nejad, Nima
  • Hagan, Holly
  • Hailu, Gessessew Bugssa
  • Hamadeh, Randah Ribhi
  • Hamidi, Samer
  • Hammami, Mouhanad
  • Hankey, Graeme J
  • Hao, Yuantao
  • Harb, Hilda L
  • Harikrishnan, Sivadasanpillai
  • Haro, Josep Maria
  • Harun, Kimani M
  • Havmoeller, Rasmus
  • Hedayati, Mohammad T
  • Heredia-Pi, Ileana Beatriz
  • Hoek, Hans W
  • Horino, Masako
  • Horita, Nobuyuki
  • Hosgood, H Dean
  • Hoy, Damian G
  • Hsairi, Mohamed
  • Hu, Guoqing
  • Huang, Hsiang
  • Huang, John J
  • Iburg, Kim Moesgaard
  • Idrisov, Bulat T
  • Innos, Kaire
  • Iyer, Veena J
  • Jacobsen, Kathryn H
  • Jahanmehr, Nader
  • Jakovljevic, Mihajlo B
  • Javanbakht, Mehdi
  • Jayatilleke, Achala Upendra
  • Jeemon, Panniyammakal
  • Jha, Vivekanand
  • Jiang, Guohong
  • Jiang, Ying
  • Jibat, Tariku
  • Jonas, Jost B
  • Kabir, Zubair
  • Kamal, Ritul
  • Kan, Haidong
  • Karch, André
  • Karema, Corine Kakizi
  • Karletsos, Dimitris
  • Kasaeian, Amir
  • Kaul, Anil
  • Kawakami, Norito
  • Kayibanda, Jeanne Françoise
  • Keiyoro, Peter Njenga
  • Kemp, Andrew Haddon
  • Kengne, Andre Pascal
  • Kesavachandran, Chandrasekharan Nair
  • Khader, Yousef Saleh
  • Khalil, Ibrahim
  • Khan, Abdur Rahman
  • Khan, Ejaz Ahmad
  • Khang, Young-Ho
  • Khubchandani, Jagdish
  • Kim, Yun Jin
  • Kinfu, Yohannes
  • Kivipelto, Miia
  • Kokubo, Yoshihiro
  • Kosen, Soewarta
  • Koul, Parvaiz A
  • Koyanagi, Ai
  • Defo, Barthelemy Kuate
  • Bicer, Burcu Kucuk
  • Kulkarni, Veena S
  • Kumar, G Anil
  • Lal, Dharmesh Kumar
  • Lam, Hilton
  • Lam, Jennifer O
  • Langan, Sinead M
  • Lansingh, Van C
  • Larsson, Anders
  • Leigh, James
  • Leung, Ricky
  • Li, Yongmei
subjects:
  • Medical And Health Sciences
  • Clinical Medicine
  • Infectious Medicine
  • Medicin Och Hälsovetenskap
  • Klinisk Medicin
  • Infektionsmedicin
ispartof: The lancet. HIV, 2016, Vol. 3(8), pp. e361-e387
description: BACKGROUND: Timely assessment of the burden of HIV/AIDS is essential for policy setting and programme evaluation. In this report from the Global Burden of Disease Study 2015 (GBD 2015), we provide national estimates of levels and trends of HIV/AIDS incidence, prevalence, coverage of antiretroviral therapy (ART), and mortality for 195 countries and territories from 1980 to 2015.METHODS: For countries without high-quality vital registration data, we estimated prevalence and incidence with data from antenatal care clinics and population-based seroprevalence surveys, and with assumptions by age and sex on initial CD4 distribution at infection, CD4 progression rates (probability of progression from higher to lower CD4 cell-count category), on and off antiretroviral therapy (ART) mortality, and mortality from all other causes. Our estimation strategy links the GBD 2015 assessment of all-cause mortality and estimation of incidence and prevalence so that for each draw from the uncertainty distribution all assumptions used in each step are internally consistent. We estimated incidence, prevalence, and death with GBD versions of the Estimation and Projection Package (EPP) and Spectrum software originally developed by the Joint United Nations Programme on HIV/AIDS (UNAIDS). We used an open-source version of EPP and recoded Spectrum for speed, and used updated assumptions from systematic reviews of the literature and GBD demographic data. For countries with high-quality vital registration data, we developed the cohort incidence bias adjustment model to estimate HIV incidence and prevalence largely from the number of deaths caused by HIV recorded in cause-of-death statistics. We corrected these statistics for garbage coding and HIV misclassification.FINDINGS: Global HIV incidence reached its peak in 1997, at 3·3 million new infections (95% uncertainty interval [UI] 3·1-3·4 million). Annual incidence has stayed relatively constant at about 2·6 million per year (range 2·5-2·8 million) since 2005, after a period of fast decline between 1997 and 2005. The number of people living with HIV/AIDS has been steadily increasing and reached 38·8 million (95% UI 37·6-40·4 million) in 2015. At the same time, HIV/AIDS mortality has been declining at a steady pace, from a peak of 1·8 million deaths (95% UI 1·7-1·9 million) in 2005, to 1·2 million deaths (1·1-1·3 million) in 2015. We recorded substantial heterogeneity in the levels and trends of HIV/AIDS across countries. Although many
language: eng
source:
identifier: ISSN: 2352-3018 ; DOI: 10.1016/S2352-3018(16)30087-X
fulltext: fulltext_linktorsrc
issn:
  • 23523018
  • 2352-3018
url: Link


@attributes
ID193206169
RANK0.07
NO1
SEARCH_ENGINEprimo_central_multiple_fe
SEARCH_ENGINE_TYPEPrimo Central Search Engine
LOCALfalse
PrimoNMBib
record
control
sourcerecordiduu-299966
sourceiddiva
recordidTN_divauu-299966
sourcesystemOther
pqid1807894097
galeid484442548
display
typearticle
titleEstimates of global, regional, and national incidence, prevalence, and mortality of HIV, 1980-2015: the Global Burden of Disease Study 2015.
creatorWang, Haidong ; Wolock, Tim M ; Carter, Austin ; Nguyen, Grant ; Kyu, Hmwe Hmwe ; Gakidou, Emmanuela ; Hay, Simon I ; Mills, Edward J ; Trickey, Adam ; Msemburi, William ; Coates, Matthew M ; Mooney, Meghan D ; Fraser, Maya S ; Sligar, Amber ; Salomon, Joshua ; Larson, Heidi J ; Friedman, Joseph ; Abajobir, Amanuel Alemu ; Abate, Kalkidan Hassen ; Abbas, Kaja M ; Razek, Mohamed Magdy Abd El ; Abd-Allah, Foad ; Abdulle, Abdishakur M ; Abera, Semaw Ferede ; Abubakar, Ibrahim ; Abu-Raddad, Laith J ; Abu-Rmeileh, Niveen M E ; Abyu, Gebre Yitayih ; Adebiyi, Akindele Olupelumi ; Adedeji, Isaac Akinkunmi ; Adelekan, Ademola Lukman ; Adofo, Koranteng ; Adou, Arsène Kouablan ; Ajala, Oluremi N ; Akinyemiju, Tomi F ; Akseer, Nadia ; Lami, Faris Hasan Al ; Al-Aly, Ziyad ; Alam, Khurshid ; Alam, Noore K M ; Alasfoor, Deena ; Aldhahri, Saleh Fahed S ; Aldridge, Robert William ; Alegretti, Miguel Angel ; Aleman, Alicia V ; Alemu, Zewdie Aderaw ; Alfonso-Cristancho, Rafael ; Ali, Raghib ; Alkerwi, Ala'a ; Alla, François ; Mohammad, Rajaa ; Al-Raddadi, Salem ; Alsharif, Ubai ; Alvarez, Elena ; Alvis-Guzman, Nelson ; Amare, Azmeraw T ; Amberbir, Alemayehu ; Amegah, Adeladza Kofi ; Ammar, Walid ; Amrock, Stephen Marc ; Antonio, Carl Abelardo T ; Anwari, Palwasha ; Ärnlöv, Johan ; Artaman, Al ; Asayesh, Hamid ; Asghar, Rana Jawad ; Assadi, Reza ; Atique, Suleman ; Atkins, Lydia S ; Avokpaho, Euripide Frinel G Arthur ; Awasthi, Ashish ; Quintanilla, Beatriz Paulina Ayala ; Bacha, Umar ; Badawi, Alaa ; Barac, Aleksandra ; Bärnighausen, Till ; Basu, Arindam ; Bayou, Tigist Assefa ; Bayou, Yibeltal Tebekaw ; Bazargan-Hejazi, Shahrzad ; Beardsley, Justin ; Bedi, Neeraj ; Bennett, Derrick A ; Bensenor, Isabela M ; Betsu, Balem Demtsu ; Beyene, Addisu Shunu ; Bhatia, Eesh ; Bhutta, Zulfiqar A ; Biadgilign, Sibhatu ; Bikbov, Boris ; Birlik, Sait Mentes ; Bisanzio, Donal ; Brainin, Michael ; Brazinova, Alexandra ; Breitborde, Nicholas J K ; Brown, Alexandria ; Burch, Michael ; Butt, Zahid A ; Campuzano, Julio Cesar ; Cárdenas, Rosario ; Carrero, Juan Jesus ; Castañeda-Orjuela, Carlos A ; Rivas, Jacqueline Castillo ; Catalá-López, Ferrán ; Chang, Hsing-Yi ; Chang, Jung-Chen ; Chavan, Laxmikant ; Chen, Wanqing ; Chiang, Peggy Pei-Chia ; Chibalabala, Mirriam ; Chisumpa, Vesper Hichilombwe ; Choi, Jee-Young Jasmine ; Christopher, Devasahayam Jesudas ; Ciobanu, Liliana G ; Cooper, Cyrus ; Dahiru, Tukur ; Damtew, Solomon Abreha ; Dandona, Lalit ; Dandona, Rakhi ; das Neves, José ; de Jager, Pieter ; De Leo, Diego ; Degenhardt, Louisa ; Dellavalle, Robert P ; Deribe, Kebede ; Deribew, Amare ; Des Jarlais, Don C ; Dharmaratne, Samath D ; Ding, Eric L ; Doshi, Pratik Pinal ; Driscoll, Tim R ; Dubey, Manisha ; Elshrek, Yousef Mohamed ; Elyazar, Iqbal ; Endries, Aman Yesuf ; Ermakov, Sergey Petrovich ; Eshrati, Babak ; Esteghamati, Alireza ; Faghmous, Imad D A ; Farinha, Carla Sofia E Sa ; Faro, Andre ; Farvid, Maryam S ; Farzadfar, Farshad ; Fereshtehnejad, Seyed-Mohammad ; Fernandes, Joao C ; Fischer, Florian ; Fitchett, Joseph Robert Ander ; Foigt, Nataliya ; Fullman, Nancy ; Fürst, Thomas ; Gankpé, Fortuné Gbètoho ; Gebre, Teshome ; Gebremedhin, Amanuel Tesfay ; Gebru, Alemseged Aregay ; Geleijnse, Johanna M ; Gessner, Bradford D ; Gething, Peter W ; Ghiwot, Tsegaye Tewelde ; Giroud, Maurice ; Gishu, Melkamu Dedefo ; Glaser, Elizabeth ; Goenka, Shifalika ; Goodridge, Amador ; Gopalani, Sameer Vali ; Goto, Atsushi ; Gugnani, Harish Chander ; Guimaraes, Mark D C ; Gupta, Rahul ; Gupta, Rajeev ; Gupta, Vipin ; Haagsma, Juanita ; Hafezi-Nejad, Nima ; Hagan, Holly ; Hailu, Gessessew Bugssa ; Hamadeh, Randah Ribhi ; Hamidi, Samer ; Hammami, Mouhanad ; Hankey, Graeme J ; Hao, Yuantao ; Harb, Hilda L ; Harikrishnan, Sivadasanpillai ; Haro, Josep Maria ; Harun, Kimani M ; Havmoeller, Rasmus ; Hedayati, Mohammad T ; Heredia-Pi, Ileana Beatriz ; Hoek, Hans W ; Horino, Masako ; Horita, Nobuyuki ; Hosgood, H Dean ; Hoy, Damian G ; Hsairi, Mohamed ; Hu, Guoqing ; Huang, Hsiang ; Huang, John J ; Iburg, Kim Moesgaard ; Idrisov, Bulat T ; Innos, Kaire ; Iyer, Veena J ; Jacobsen, Kathryn H ; Jahanmehr, Nader ; Jakovljevic, Mihajlo B ; Javanbakht, Mehdi ; Jayatilleke, Achala Upendra ; Jeemon, Panniyammakal ; Jha, Vivekanand ; Jiang, Guohong ; Jiang, Ying ; Jibat, Tariku ; Jonas, Jost B ; Kabir, Zubair ; Kamal, Ritul ; Kan, Haidong ; Karch, André ; Karema, Corine Kakizi ; Karletsos, Dimitris ; Kasaeian, Amir ; Kaul, Anil ; Kawakami, Norito ; Kayibanda, Jeanne Françoise ; Keiyoro, Peter Njenga ; Kemp, Andrew Haddon ; Kengne, Andre Pascal ; Kesavachandran, Chandrasekharan Nair ; Khader, Yousef Saleh ; Khalil, Ibrahim ; Khan, Abdur Rahman ; Khan, Ejaz Ahmad ; Khang, Young-Ho ; Khubchandani, Jagdish ; Kim, Yun Jin ; Kinfu, Yohannes ; Kivipelto, Miia ; Kokubo, Yoshihiro ; Kosen, Soewarta ; Koul, Parvaiz A ; Koyanagi, Ai ; Defo, Barthelemy Kuate ; Bicer, Burcu Kucuk ; Kulkarni, Veena S ; Kumar, G Anil ; Lal, Dharmesh Kumar ; Lam, Hilton ; Lam, Jennifer O ; Langan, Sinead M ; Lansingh, Van C ; Larsson, Anders ; Leigh, James ; Leung, Ricky ; Li, Yongmei
contributorUppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för medicinska vetenskaper, Kardiovaskulär epidemiologi ; Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för medicinska vetenskaper, Biokemisk struktur och funktion
ispartofThe lancet. HIV, 2016, Vol. 3(8), pp. e361-e387
identifierISSN: 2352-3018 ; DOI: 10.1016/S2352-3018(16)30087-X
subjectMedical And Health Sciences ; Clinical Medicine ; Infectious Medicine ; Medicin Och Hälsovetenskap ; Klinisk Medicin ; Infektionsmedicin
descriptionBACKGROUND: Timely assessment of the burden of HIV/AIDS is essential for policy setting and programme evaluation. In this report from the Global Burden of Disease Study 2015 (GBD 2015), we provide national estimates of levels and trends of HIV/AIDS incidence, prevalence, coverage of antiretroviral therapy (ART), and mortality for 195 countries and territories from 1980 to 2015.METHODS: For countries without high-quality vital registration data, we estimated prevalence and incidence with data from antenatal care clinics and population-based seroprevalence surveys, and with assumptions by age and sex on initial CD4 distribution at infection, CD4 progression rates (probability of progression from higher to lower CD4 cell-count category), on and off antiretroviral therapy (ART) mortality, and mortality from all other causes. Our estimation strategy links the GBD 2015 assessment of all-cause mortality and estimation of incidence and prevalence so that for each draw from the uncertainty distribution all assumptions used in each step are internally consistent. We estimated incidence, prevalence, and death with GBD versions of the Estimation and Projection Package (EPP) and Spectrum software originally developed by the Joint United Nations Programme on HIV/AIDS (UNAIDS). We used an open-source version of EPP and recoded Spectrum for speed, and used updated assumptions from systematic reviews of the literature and GBD demographic data. For countries with high-quality vital registration data, we developed the cohort incidence bias adjustment model to estimate HIV incidence and prevalence largely from the number of deaths caused by HIV recorded in cause-of-death statistics. We corrected these statistics for garbage coding and HIV misclassification.FINDINGS: Global HIV incidence reached its peak in 1997, at 3·3 million new infections (95% uncertainty interval [UI] 3·1-3·4 million). Annual incidence has stayed relatively constant at about 2·6 million per year (range 2·5-2·8 million) since 2005, after a period of fast decline between 1997 and 2005. The number of people living with HIV/AIDS has been steadily increasing and reached 38·8 million (95% UI 37·6-40·4 million) in 2015. At the same time, HIV/AIDS mortality has been declining at a steady pace, from a peak of 1·8 million deaths (95% UI 1·7-1·9 million) in 2005, to 1·2 million deaths (1·1-1·3 million) in 2015. We recorded substantial heterogeneity in the levels and trends of HIV/AIDS across countries. Although many countries have experienced decreases in HIV/AIDS mortality and in annual new infections, other countries have had slowdowns or increases in rates of change in annual new infections.INTERPRETATION: Scale-up of ART and prevention of mother-to-child transmission has been one of the great successes of global health in the past two decades. However, in the past decade, progress in reducing new infections has been slow, development assistance for health devoted to HIV has stagnated, and resources for health in low-income countries have grown slowly. Achievement of the new ambitious goals for HIV enshrined in Sustainable Development Goal 3 and the 90-90-90 UNAIDS targets will be challenging, and will need continued efforts from governments and international agencies in the next 15 years to end AIDS by 2030.
languageeng
source
version11
oafree_for_read
lds50peer_reviewed
links
openurl$$Topenurl_article
backlink$$Uhttp://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-299966$$EView_this_record_in_Uppsala_University_Library
linktorsrc$$Uhttp://uu.diva-portal.org/smash/get/diva2:950523/FULLTEXT01.pdf$$EView_full_text_in_Uppsala_University_Library
openurlfulltext$$Topenurlfull_article
search
creatorcontrib
0Wang, Haidong
1Wolock, Tim M
2Carter, Austin
3Nguyen, Grant
4Kyu, Hmwe Hmwe
5Gakidou, Emmanuela
6Hay, Simon I
7Mills, Edward J
8Trickey, Adam
9Msemburi, William
10Coates, Matthew M
11Mooney, Meghan D
12Fraser, Maya S
13Sligar, Amber
14Salomon, Joshua
15Larson, Heidi J
16Friedman, Joseph
17Abajobir, Amanuel Alemu
18Abate, Kalkidan Hassen
19Abbas, Kaja M
20Razek, Mohamed Magdy Abd El
21Abd-Allah, Foad
22Abdulle, Abdishakur M
23Abera, Semaw Ferede
24Abubakar, Ibrahim
25Abu-Raddad, Laith J
26Abu-Rmeileh, Niveen M E
27Abyu, Gebre Yitayih
28Adebiyi, Akindele Olupelumi
29Adedeji, Isaac Akinkunmi
30Adelekan, Ademola Lukman
31Adofo, Koranteng
32Adou, Arsène Kouablan
33Ajala, Oluremi N
34Akinyemiju, Tomi F
35Akseer, Nadia
36Lami, Faris Hasan Al
37Al-Aly, Ziyad
38Alam, Khurshid
39Alam, Noore K M
40Alasfoor, Deena
41Aldhahri, Saleh Fahed S
42Aldridge, Robert William
43Alegretti, Miguel Angel
44Aleman, Alicia V
45Alemu, Zewdie Aderaw
46Alfonso-Cristancho, Rafael
47Ali, Raghib
48Alkerwi, Ala'a
49Alla, François
50Mohammad, Rajaa
51Al-Raddadi, Salem
52Alsharif, Ubai
53Alvarez, Elena
54Alvis-Guzman, Nelson
55Amare, Azmeraw T
56Amberbir, Alemayehu
57Amegah, Adeladza Kofi
58Ammar, Walid
59Amrock, Stephen Marc
60Antonio, Carl Abelardo T
61Anwari, Palwasha
62Ärnlöv, Johan
63Artaman, Al
64Asayesh, Hamid
65Asghar, Rana Jawad
66Assadi, Reza
67Atique, Suleman
68Atkins, Lydia S
69Avokpaho, Euripide Frinel G Arthur
70Awasthi, Ashish
71Quintanilla, Beatriz Paulina Ayala
72Bacha, Umar
73Badawi, Alaa
74Barac, Aleksandra
75Bärnighausen, Till
76Basu, Arindam
77Bayou, Tigist Assefa
78Bayou, Yibeltal Tebekaw
79Bazargan-Hejazi, Shahrzad
80Beardsley, Justin
81Bedi, Neeraj
82Bennett, Derrick A
83Bensenor, Isabela M
84Betsu, Balem Demtsu
85Beyene, Addisu Shunu
86Bhatia, Eesh
87Bhutta, Zulfiqar A
88Biadgilign, Sibhatu
89Bikbov, Boris
90Birlik, Sait Mentes
91Bisanzio, Donal
92Brainin, Michael
93Brazinova, Alexandra
94Breitborde, Nicholas J K
95Brown, Alexandria
96Burch, Michael
97Butt, Zahid A
98Campuzano, Julio Cesar
99Cárdenas, Rosario
100...
titleEstimates of global, regional, and national incidence, prevalence, and mortality of HIV, 1980-2015: the Global Burden of Disease Study 2015.
descriptionBACKGROUND: Timely assessment of the burden of HIV/AIDS is essential for policy setting and programme evaluation. In this report from the Global Burden of Disease Study 2015 (GBD 2015), we provide national estimates of levels and trends of HIV/AIDS incidence, prevalence, coverage of antiretroviral therapy (ART), and mortality for 195 countries and territories from 1980 to 2015.METHODS: For countries without high-quality vital registration data, we estimated prevalence and incidence with data from antenatal care clinics and population-based seroprevalence surveys, and with assumptions by age and sex on initial CD4 distribution at infection, CD4 progression rates (probability of progression from higher to lower CD4 cell-count category), on and off antiretroviral therapy (ART) mortality, and mortality from all other causes. Our estimation strategy links the GBD 2015 assessment of all-cause mortality and estimation of incidence and prevalence so that for each draw from the uncertainty distribution all assumptions used in each step are internally consistent. We estimated incidence, prevalence, and death with GBD versions of the Estimation and Projection Package (EPP) and Spectrum software originally developed by the Joint United Nations Programme on HIV/AIDS (UNAIDS). We used an open-source version of EPP and recoded Spectrum for speed, and used updated assumptions from systematic reviews of the literature and GBD demographic data. For countries with high-quality vital registration data, we developed the cohort incidence bias adjustment model to estimate HIV incidence and prevalence largely from the number of deaths caused by HIV recorded in cause-of-death statistics. We corrected these statistics for garbage coding and HIV misclassification.FINDINGS: Global HIV incidence reached its peak in 1997, at 3·3 million new infections (95% uncertainty interval [UI] 3·1-3·4 million). Annual incidence has stayed relatively constant at about 2·6 million per year (range 2·5-2·8 million) since 2005, after a period of fast decline between 1997 and 2005. The number of people living with HIV/AIDS has been steadily increasing and reached 38·8 million (95% UI 37·6-40·4 million) in 2015. At the same time, HIV/AIDS mortality has been declining at a steady pace, from a peak of 1·8 million deaths (95% UI 1·7-1·9 million) in 2005, to 1·2 million deaths (1·1-1·3 million) in 2015. We recorded substantial heterogeneity in the levels and trends of HIV/AIDS across countries. Although many countries have experienced decreases in HIV/AIDS mortality and in annual new infections, other countries have had slowdowns or increases in rates of change in annual new infections.INTERPRETATION: Scale-up of ART and prevention of mother-to-child transmission has been one of the great successes of global health in the past two decades. However, in the past decade, progress in reducing new infections has been slow, development assistance for health devoted to HIV has stagnated, and resources for health in low-income countries have grown slowly. Achievement of the new ambitious goals for HIV enshrined in Sustainable Development Goal 3 and the 90-90-90 UNAIDS targets will be challenging, and will need continued efforts from governments and international agencies in the next 15 years to end AIDS by 2030.
subject
0Medical And Health Sciences
1Clinical Medicine
2Infectious Medicine
3Medicin Och Hälsovetenskap
4Klinisk Medicin
5Infektionsmedicin
general
0English
1Uppsala University Library
2refereed
3ref
4Refereed
5Refereegranskat
6Fagfellevurdert
7article
8art
9Article in journal
10Artikel i tidskrift
11Artikkel i tidsskrift
12
13Published
1410.1016/S2352-3018(16)30087-X
15DiVA - Academic Archive Online
sourceiddiva
recordiddivauu-299966
issn
023523018
12352-3018
rsrctypearticle
creationdate2016
addtitleThe lancet. HIV
searchscopediva
scopediva
lsr30VSR-Enriched:[orcidid, pqid, galeid]
sort
titleEstimates of global, regional, and national incidence, prevalence, and mortality of HIV, 1980-2015: the Global Burden of Disease Study 2015.
authorWang, Haidong ; Wolock, Tim M ; Carter, Austin ; Nguyen, Grant ; Kyu, Hmwe Hmwe ; Gakidou, Emmanuela ; Hay, Simon I ; Mills, Edward J ; Trickey, Adam ; Msemburi, William ; Coates, Matthew M ; Mooney, Meghan D ; Fraser, Maya S ; Sligar, Amber ; Salomon, Joshua ; Larson, Heidi J ; Friedman, Joseph ; Abajobir, Amanuel Alemu ; Abate, Kalkidan Hassen ; Abbas, Kaja M ; Razek, Mohamed Magdy Abd El ; Abd-Allah, Foad ; Abdulle, Abdishakur M ; Abera, Semaw Ferede ; Abubakar, Ibrahim ; Abu-Raddad, Laith J ; Abu-Rmeileh, Niveen M E ; Abyu, Gebre Yitayih ; Adebiyi, Akindele Olupelumi ; Adedeji, Isaac Akinkunmi ; Adelekan, Ademola Lukman ; Adofo, Koranteng ; Adou, Arsène Kouablan ; Ajala, Oluremi N ; Akinyemiju, Tomi F ; Akseer, Nadia ; Lami, Faris Hasan Al ; Al-Aly, Ziyad ; Alam, Khurshid ; Alam, Noore K M ; Alasfoor, Deena ; Aldhahri, Saleh Fahed S ; Aldridge, Robert William ; Alegretti, Miguel Angel ; Aleman, Alicia V ; Alemu, Zewdie Aderaw ; Alfonso-Cristancho, Rafael ; Ali, Raghib ; Alkerwi, Ala'a ; Alla, François ; Mohammad, Rajaa ; Al-Raddadi, Salem ; Alsharif, Ubai ; Alvarez, Elena ; Alvis-Guzman, Nelson ; Amare, Azmeraw T ; Amberbir, Alemayehu ; Amegah, Adeladza Kofi ; Ammar, Walid ; Amrock, Stephen Marc ; Antonio, Carl Abelardo T ; Anwari, Palwasha ; Ärnlöv, Johan ; Artaman, Al ; Asayesh, Hamid ; Asghar, Rana Jawad ; Assadi, Reza ; Atique, Suleman ; Atkins, Lydia S ; Avokpaho, Euripide Frinel G Arthur ; Awasthi, Ashish ; Quintanilla, Beatriz Paulina Ayala ; Bacha, Umar ; Badawi, Alaa ; Barac, Aleksandra ; Bärnighausen, Till ; Basu, Arindam ; Bayou, Tigist Assefa ; Bayou, Yibeltal Tebekaw ; Bazargan-Hejazi, Shahrzad ; Beardsley, Justin ; Bedi, Neeraj ; Bennett, Derrick A ; Bensenor, Isabela M ; Betsu, Balem Demtsu ; Beyene, Addisu Shunu ; Bhatia, Eesh ; Bhutta, Zulfiqar A ; Biadgilign, Sibhatu ; Bikbov, Boris ; Birlik, Sait Mentes ; Bisanzio, Donal ; Brainin, Michael ; Brazinova, Alexandra ; Breitborde, Nicholas J K ; Brown, Alexandria ; Burch, Michael ; Butt, Zahid A ; Campuzano, Julio Cesar ; Cárdenas, Rosario ; Carrero, Juan Jesus ; Castañeda-Orjuela, Carlos A ; Rivas, Jacqueline Castillo ; Catalá-López, Ferrán ; Chang, Hsing-Yi ; Chang, Jung-Chen ; Chavan, Laxmikant ; Chen, Wanqing ; Chiang, Peggy Pei-Chia ; Chibalabala, Mirriam ; Chisumpa, Vesper Hichilombwe ; Choi, Jee-Young Jasmine ; Christopher, Devasahayam Jesudas ; Ciobanu, Liliana G ; Cooper, Cyrus ; Dahiru, Tukur ; Damtew, Solomon Abreha ; Dandona, Lalit ; Dandona, Rakhi ; das Neves, José ; de Jager, Pieter ; De Leo, Diego ; Degenhardt, Louisa ; Dellavalle, Robert P ; Deribe, Kebede ; Deribew, Amare ; Des Jarlais, Don C ; Dharmaratne, Samath D ; Ding, Eric L ; Doshi, Pratik Pinal ; Driscoll, Tim R ; Dubey, Manisha ; Elshrek, Yousef Mohamed ; Elyazar, Iqbal ; Endries, Aman Yesuf ; Ermakov, Sergey Petrovich ; Eshrati, Babak ; Esteghamati, Alireza ; Faghmous, Imad D A ; Farinha, Carla Sofia E Sa ; Faro, Andre ; Farvid, Maryam S ; Farzadfar, Farshad ; Fereshtehnejad, Seyed-Mohammad ; Fernandes, Joao C ; Fischer, Florian ; Fitchett, Joseph Robert Ander ; Foigt, Nataliya ; Fullman, Nancy ; Fürst, Thomas ; Gankpé, Fortuné Gbètoho ; Gebre, Teshome ; Gebremedhin, Amanuel Tesfay ; Gebru, Alemseged Aregay ; Geleijnse, Johanna M ; Gessner, Bradford D ; Gething, Peter W ; Ghiwot, Tsegaye Tewelde ; Giroud, Maurice ; Gishu, Melkamu Dedefo ; Glaser, Elizabeth ; Goenka, Shifalika ; Goodridge, Amador ; Gopalani, Sameer Vali ; Goto, Atsushi ; Gugnani, Harish Chander ; Guimaraes, Mark D C ; Gupta, Rahul ; Gupta, Rajeev ; Gupta, Vipin ; Haagsma, Juanita ; Hafezi-Nejad, Nima ; Hagan, Holly ; Hailu, Gessessew Bugssa ; Hamadeh, Randah Ribhi ; Hamidi, Samer ; Hammami, Mouhanad ; Hankey, Graeme J ; Hao, Yuantao ; Harb, Hilda L ; Harikrishnan, Sivadasanpillai ; Haro, Josep Maria ; Harun, Kimani M ; Havmoeller, Rasmus ; Hedayati, Mohammad T ; Heredia-Pi, Ileana Beatriz ; Hoek, Hans W ; Horino, Masako ; Horita, Nobuyuki ; Hosgood, H Dean ; Hoy, Damian G ; Hsairi, Mohamed ; Hu, Guoqing ; Huang, Hsiang ; Huang, John J ; Iburg, Kim Moesgaard ; Idrisov, Bulat T ; Innos, Kaire ; Iyer, Veena J ; Jacobsen, Kathryn H ; Jahanmehr, Nader ; Jakovljevic, Mihajlo B ; Javanbakht, Mehdi ; Jayatilleke, Achala Upendra ; Jeemon, Panniyammakal ; Jha, Vivekanand ; Jiang, Guohong ; Jiang, Ying ; Jibat, Tariku ; Jonas, Jost B ; Kabir, Zubair ; Kamal, Ritul ; Kan, Haidong ; Karch, André ; Karema, Corine Kakizi ; Karletsos, Dimitris ; Kasaeian, Amir ; Kaul, Anil ; Kawakami, Norito ; Kayibanda, Jeanne Françoise ; Keiyoro, Peter Njenga ; Kemp, Andrew Haddon ; Kengne, Andre Pascal ; Kesavachandran, Chandrasekharan Nair ; Khader, Yousef Saleh ; Khalil, Ibrahim ; Khan, Abdur Rahman ; Khan, Ejaz Ahmad ; Khang, Young-Ho ; Khubchandani, Jagdish ; Kim, Yun Jin ; Kinfu, Yohannes ; Kivipelto, Miia ; Kokubo, Yoshihiro ; Kosen, Soewarta ; Koul, Parvaiz A ; Koyanagi, Ai ; Defo, Barthelemy Kuate ; Bicer, Burcu Kucuk ; Kulkarni, Veena S ; Kumar, G Anil ; Lal, Dharmesh Kumar ; Lam, Hilton ; Lam, Jennifer O ; Langan, Sinead M ; Lansingh, Van C ; Larsson, Anders ; Leigh, James ; Leung, Ricky ; Li, Yongmei
creationdate20160000
facets
frbrgroupid9201975421351615356
frbrtype5
newrecords20171123
languageeng
creationdate2016
topic
0Medical And Health Sciences
1Clinical Medicine
2Infectious Medicine
3Medicin Och Hälsovetenskap
4Klinisk Medicin
5Infektionsmedicin
collectionDiVA - Academic Archive Online
prefilterarticles
rsrctypearticles
creatorcontrib
0Wang, Haidong
1Wolock, Tim M
2Carter, Austin
3Nguyen, Grant
4Kyu, Hmwe Hmwe
5Gakidou, Emmanuela
6Hay, Simon I
7Mills, Edward J
8Trickey, Adam
9Msemburi, William
10Coates, Matthew M
11Mooney, Meghan D
12Fraser, Maya S
13Sligar, Amber
14Salomon, Joshua
15Larson, Heidi J
16Friedman, Joseph
17Abajobir, Amanuel Alemu
18Abate, Kalkidan Hassen
19Abbas, Kaja M
20Razek, Mohamed Magdy Abd El
21Abd-Allah, Foad
22Abdulle, Abdishakur M
23Abera, Semaw Ferede
24Abubakar, Ibrahim
25Abu-Raddad, Laith J
26Abu-Rmeileh, Niveen M E
27Abyu, Gebre Yitayih
28Adebiyi, Akindele Olupelumi
29Adedeji, Isaac Akinkunmi
30Adelekan, Ademola Lukman
31Adofo, Koranteng
32Adou, Arsène Kouablan
33Ajala, Oluremi N
34Akinyemiju, Tomi F
35Akseer, Nadia
36Lami, Faris Hasan Al
37Al-Aly, Ziyad
38Alam, Khurshid
39Alam, Noore K M
40Alasfoor, Deena
41Aldhahri, Saleh Fahed S
42Aldridge, Robert William
43Alegretti, Miguel Angel
44Aleman, Alicia V
45Alemu, Zewdie Aderaw
46Alfonso-Cristancho, Rafael
47Ali, Raghib
48Alkerwi, Ala'a
49Alla, François
50Mohammad, Rajaa
51Al-Raddadi, Salem
52Alsharif, Ubai
53Alvarez, Elena
54Alvis-Guzman, Nelson
55Amare, Azmeraw T
56Amberbir, Alemayehu
57Amegah, Adeladza Kofi
58Ammar, Walid
59Amrock, Stephen Marc
60Antonio, Carl Abelardo T
61Anwari, Palwasha
62Ärnlöv, Johan
63Artaman, Al
64Asayesh, Hamid
65Asghar, Rana Jawad
66Assadi, Reza
67Atique, Suleman
68Atkins, Lydia S
69Avokpaho, Euripide Frinel G Arthur
70Awasthi, Ashish
71Quintanilla, Beatriz Paulina Ayala
72Bacha, Umar
73Badawi, Alaa
74Barac, Aleksandra
75Bärnighausen, Till
76Basu, Arindam
77Bayou, Tigist Assefa
78Bayou, Yibeltal Tebekaw
79Bazargan-Hejazi, Shahrzad
80Beardsley, Justin
81Bedi, Neeraj
82Bennett, Derrick A
83Bensenor, Isabela M
84Betsu, Balem Demtsu
85Beyene, Addisu Shunu
86Bhatia, Eesh
87Bhutta, Zulfiqar A
88Biadgilign, Sibhatu
89Bikbov, Boris
90Birlik, Sait Mentes
91Bisanzio, Donal
92Brainin, Michael
93Brazinova, Alexandra
94Breitborde, Nicholas J K
95Brown, Alexandria
96Burch, Michael
97Butt, Zahid A
98Campuzano, Julio Cesar
99Cárdenas, Rosario
100...
jtitleThe lancet. HIV
toplevelpeer_reviewed
delivery
delcategoryRemote Search Resource
fulltextfulltext_linktorsrc
addata
aulast
0Wang
1Wolock
2Carter
3Nguyen
4Kyu
5Gakidou
6Hay
7Mills
8Trickey
9Msemburi
10Coates
11Mooney
12Fraser
13Sligar
14Salomon
15Larson
16Friedman
17Abajobir
18Abate
19Abbas
20Razek
21Abd-Allah
22Abdulle
23Abera
24Abubakar
25Abu-Raddad
26Abu-Rmeileh
27Abyu
28Adebiyi
29Adedeji
30Adelekan
31Adofo
32Adou
33Ajala
34Akinyemiju
35Akseer
36Lami
37Al-Aly
38Alam
39Alasfoor
40Aldhahri
41Aldridge
42Alegretti
43Aleman
44Alemu
45Alfonso-Cristancho
46Ali
47Alkerwi
48Alla
49Mohammad
50Al-Raddadi
51Alsharif
52Alvarez
53Alvis-Guzman
54Amare
55Amberbir
56Amegah
57Ammar
58Amrock
59Antonio
60Anwari
61Ärnlöv
62Artaman
63Asayesh
64Asghar
65Assadi
66Atique
67Atkins
68Avokpaho
69Awasthi
70Quintanilla
71Bacha
72Badawi
73Barac
74Bärnighausen
75Basu
76Bayou
77Bazargan-Hejazi
78Beardsley
79Bedi
80Bennett
81Bensenor
82Betsu
83Beyene
84Bhatia
85Bhutta
86Biadgilign
87Bikbov
88Birlik
89Bisanzio
90Brainin
91Brazinova
92Breitborde
93Brown
94Burch
95Butt
96Campuzano
97Cárdenas
98Carrero
99Castañeda-Orjuela
100...
aufirst
0Haidong
1Tim M
2Austin
3Grant
4Hmwe Hmwe
5Emmanuela
6Simon I
7Edward J
8Adam
9William
10Matthew M
11Meghan D
12Maya S
13Amber
14Joshua
15Heidi J
16Joseph
17Amanuel Alemu
18Kalkidan Hassen
19Kaja M
20Mohamed Magdy Abd El
21Foad
22Abdishakur M
23Semaw Ferede
24Ibrahim
25Laith J
26Niveen M E
27Gebre Yitayih
28Akindele Olupelumi
29Isaac Akinkunmi
30Ademola Lukman
31Koranteng
32Arsène Kouablan
33Oluremi N
34Tomi F
35Nadia
36Faris Hasan Al
37Ziyad
38Khurshid
39Noore K M
40Deena
41Saleh Fahed S
42Robert William
43Miguel Angel
44Alicia V
45Zewdie Aderaw
46Rafael
47Raghib
48Ala'a
49François
50Rajaa
51Salem
52Ubai
53Elena
54Nelson
55Azmeraw T
56Alemayehu
57Adeladza Kofi
58Walid
59Stephen Marc
60Carl Abelardo T
61Palwasha
62Johan
63Al
64Hamid
65Rana Jawad
66Reza
67Suleman
68Lydia S
69Euripide Frinel G Arthur
70Ashish
71Beatriz Paulina Ayala
72Umar
73Alaa
74Aleksandra
75Till
76Arindam
77Tigist Assefa
78Yibeltal Tebekaw
79Shahrzad
80Justin
81Neeraj
82Derrick A
83Isabela M
84Balem Demtsu
85Addisu Shunu
86Eesh
87Zulfiqar A
88Sibhatu
89Boris
90Sait Mentes
91Donal
92Michael
93Alexandra
94Nicholas J K
95Alexandria
96Zahid A
97Julio Cesar
98Rosario
99Juan Jesus
100...
au
0Wang, Haidong
1Wolock, Tim M
2Carter, Austin
3Nguyen, Grant
4Kyu, Hmwe Hmwe
5Gakidou, Emmanuela
6Hay, Simon I
7Mills, Edward J
8Trickey, Adam
9Msemburi, William
10Coates, Matthew M
11Mooney, Meghan D
12Fraser, Maya S
13Sligar, Amber
14Salomon, Joshua
15Larson, Heidi J
16Friedman, Joseph
17Abajobir, Amanuel Alemu
18Abate, Kalkidan Hassen
19Abbas, Kaja M
20Razek, Mohamed Magdy Abd El
21Abd-Allah, Foad
22Abdulle, Abdishakur M
23Abera, Semaw Ferede
24Abubakar, Ibrahim
25Abu-Raddad, Laith J
26Abu-Rmeileh, Niveen M E
27Abyu, Gebre Yitayih
28Adebiyi, Akindele Olupelumi
29Adedeji, Isaac Akinkunmi
30Adelekan, Ademola Lukman
31Adofo, Koranteng
32Adou, Arsène Kouablan
33Ajala, Oluremi N
34Akinyemiju, Tomi F
35Akseer, Nadia
36Lami, Faris Hasan Al
37Al-Aly, Ziyad
38Alam, Khurshid
39Alam, Noore K M
40Alasfoor, Deena
41Aldhahri, Saleh Fahed S
42Aldridge, Robert William
43Alegretti, Miguel Angel
44Aleman, Alicia V
45Alemu, Zewdie Aderaw
46Alfonso-Cristancho, Rafael
47Ali, Raghib
48Alkerwi, Ala'a
49Alla, François
50Mohammad, Rajaa
51Al-Raddadi, Salem
52Alsharif, Ubai
53Alvarez, Elena
54Alvis-Guzman, Nelson
55Amare, Azmeraw T
56Amberbir, Alemayehu
57Amegah, Adeladza Kofi
58Ammar, Walid
59Amrock, Stephen Marc
60Antonio, Carl Abelardo T
61Anwari, Palwasha
62Ärnlöv, Johan
63Artaman, Al
64Asayesh, Hamid
65Asghar, Rana Jawad
66Assadi, Reza
67Atique, Suleman
68Atkins, Lydia S
69Avokpaho, Euripide Frinel G Arthur
70Awasthi, Ashish
71Quintanilla, Beatriz Paulina Ayala
72Bacha, Umar
73Badawi, Alaa
74Barac, Aleksandra
75Bärnighausen, Till
76Basu, Arindam
77Bayou, Tigist Assefa
78Bayou, Yibeltal Tebekaw
79Bazargan-Hejazi, Shahrzad
80Beardsley, Justin
81Bedi, Neeraj
82Bennett, Derrick A
83Bensenor, Isabela M
84Betsu, Balem Demtsu
85Beyene, Addisu Shunu
86Bhatia, Eesh
87Bhutta, Zulfiqar A
88Biadgilign, Sibhatu
89Bikbov, Boris
90Birlik, Sait Mentes
91Bisanzio, Donal
92Brainin, Michael
93Brazinova, Alexandra
94Breitborde, Nicholas J K
95Brown, Alexandria
96Burch, Michael
97Butt, Zahid A
98Campuzano, Julio Cesar
99Cárdenas, Rosario
100...
aucorp
0Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för medicinska vetenskaper, Kardiovaskulär epidemiologi
1Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för medicinska vetenskaper, Biokemisk struktur och funktion
atitleEstimates of global, regional, and national incidence, prevalence, and mortality of HIV, 1980-2015: the Global Burden of Disease Study 2015.
jtitleThe lancet. HIV
date2016
risdate2016
volume3
issue8
spagee361
epagee387
pagese361-e387
issn2352-3018
formatjournal
genrearticle
ristypeJOUR
abstractBACKGROUND: Timely assessment of the burden of HIV/AIDS is essential for policy setting and programme evaluation. In this report from the Global Burden of Disease Study 2015 (GBD 2015), we provide national estimates of levels and trends of HIV/AIDS incidence, prevalence, coverage of antiretroviral therapy (ART), and mortality for 195 countries and territories from 1980 to 2015.METHODS: For countries without high-quality vital registration data, we estimated prevalence and incidence with data from antenatal care clinics and population-based seroprevalence surveys, and with assumptions by age and sex on initial CD4 distribution at infection, CD4 progression rates (probability of progression from higher to lower CD4 cell-count category), on and off antiretroviral therapy (ART) mortality, and mortality from all other causes. Our estimation strategy links the GBD 2015 assessment of all-cause mortality and estimation of incidence and prevalence so that for each draw from the uncertainty distribution all assumptions used in each step are internally consistent. We estimated incidence, prevalence, and death with GBD versions of the Estimation and Projection Package (EPP) and Spectrum software originally developed by the Joint United Nations Programme on HIV/AIDS (UNAIDS). We used an open-source version of EPP and recoded Spectrum for speed, and used updated assumptions from systematic reviews of the literature and GBD demographic data. For countries with high-quality vital registration data, we developed the cohort incidence bias adjustment model to estimate HIV incidence and prevalence largely from the number of deaths caused by HIV recorded in cause-of-death statistics. We corrected these statistics for garbage coding and HIV misclassification.FINDINGS: Global HIV incidence reached its peak in 1997, at 3·3 million new infections (95% uncertainty interval [UI] 3·1-3·4 million). Annual incidence has stayed relatively constant at about 2·6 million per year (range 2·5-2·8 million) since 2005, after a period of fast decline between 1997 and 2005. The number of people living with HIV/AIDS has been steadily increasing and reached 38·8 million (95% UI 37·6-40·4 million) in 2015. At the same time, HIV/AIDS mortality has been declining at a steady pace, from a peak of 1·8 million deaths (95% UI 1·7-1·9 million) in 2005, to 1·2 million deaths (1·1-1·3 million) in 2015. We recorded substantial heterogeneity in the levels and trends of HIV/AIDS across countries. Although many countries have experienced decreases in HIV/AIDS mortality and in annual new infections, other countries have had slowdowns or increases in rates of change in annual new infections.INTERPRETATION: Scale-up of ART and prevention of mother-to-child transmission has been one of the great successes of global health in the past two decades. However, in the past decade, progress in reducing new infections has been slow, development assistance for health devoted to HIV has stagnated, and resources for health in low-income countries have grown slowly. Achievement of the new ambitious goals for HIV enshrined in Sustainable Development Goal 3 and the 90-90-90 UNAIDS targets will be challenging, and will need continued efforts from governments and international agencies in the next 15 years to end AIDS by 2030.
doi10.1016/S2352-3018(16)30087-X
orcidid0000-0002-6933-4637
oafree_for_read