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Association between serum ferritin and osteocalcin as a potential mechanism explaining the iron-induced insulin resistance

BACKGROUND: Increased iron stores are associated with increased risk of type 2 diabetes, however, the mechanisms underlying these associations are poorly understood. Because a reduction of circulating osteocalcin levels after iron overload have been demonstrated in cell cultures, and osteocalcin...

Journal Title: PLoS ONE 01 January 2013, Vol.8(10), p.e76433
Main Author: Martí Juanola-Falgarona
Other Authors: José Cándido-Fernández , Jordi Salas-Salvadó , Miguel A Martínez-González , Ramón Estruch , Miquel Fiol , Victoria Arija-Val , Mònica Bulló , Predimed Study Investigators
Format: Electronic Article Electronic Article
Language: English
Subjects:
ID: E-ISSN: 1932-6203 ; DOI: 10.1371/journal.pone.0076433
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title: Association between serum ferritin and osteocalcin as a potential mechanism explaining the iron-induced insulin resistance
format: Article
creator:
  • Martí Juanola-Falgarona
  • José Cándido-Fernández
  • Jordi Salas-Salvadó
  • Miguel A Martínez-González
  • Ramón Estruch
  • Miquel Fiol
  • Victoria Arija-Val
  • Mònica Bulló
  • Predimed Study Investigators
subjects:
  • Sciences (General)
ispartof: PLoS ONE, 01 January 2013, Vol.8(10), p.e76433
description: BACKGROUND: Increased iron stores are associated with increased risk of type 2 diabetes, however, the mechanisms underlying these associations are poorly understood. Because a reduction of circulating osteocalcin levels after iron overload have been demonstrated in cell cultures, and osteocalcin...
language: eng
source:
identifier: E-ISSN: 1932-6203 ; DOI: 10.1371/journal.pone.0076433
fulltext: fulltext_linktorsrc
issn:
  • 1932-6203
  • 19326203
url: Link


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BACKGROUND: Increased iron stores are associated with increased risk of type 2 diabetes, however, the mechanisms underlying these associations are poorly understood. Because a reduction of circulating osteocalcin levels after iron overload have been demonstrated in cell cultures, and osteocalcin...

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BACKGROUND: Increased iron stores are associated with increased risk of type 2 diabetes, however, the mechanisms underlying these associations are poorly understood. Because a reduction of circulating osteocalcin levels after iron overload have been demonstrated in cell cultures, and osteocalcin...

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