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Gene expression analysis suggests bone development-related genes GDF5 and DIO2 are involved in the development of Kashin-Beck disease in children rather than adults

To investigate the differences in gene expression between children and adults with Kashin-Beck disease (KBD).12 children with KBD and 12 healthy children were selected and divided into 4 KBD vs. control pairs matched according to age and gender, with each pair having 3 KBD children and 3 healthy...

Journal Title: PLoS ONE 01 January 2014, Vol.9(7), p.e103618
Main Author: Yan Wen
Other Authors: Feng Zhang , Chunyan Li , Shulan He , Wuhong Tan , Yanxia Lei , Qiang Zhang , Hanjie Yu , Jingjing Zheng , Xiong Guo
Format: Electronic Article Electronic Article
Language: English
Subjects:
ID: E-ISSN: 1932-6203 ; DOI: 10.1371/journal.pone.0103618
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recordid: doaj_soai_doaj_org_article_5187da9235e648ada7af92db4cc96d0a
title: Gene expression analysis suggests bone development-related genes GDF5 and DIO2 are involved in the development of Kashin-Beck disease in children rather than adults
format: Article
creator:
  • Yan Wen
  • Feng Zhang
  • Chunyan Li
  • Shulan He
  • Wuhong Tan
  • Yanxia Lei
  • Qiang Zhang
  • Hanjie Yu
  • Jingjing Zheng
  • Xiong Guo
subjects:
  • Sciences (General)
ispartof: PLoS ONE, 01 January 2014, Vol.9(7), p.e103618
description: To investigate the differences in gene expression between children and adults with Kashin-Beck disease (KBD).12 children with KBD and 12 healthy children were selected and divided into 4 KBD vs. control pairs matched according to age and gender, with each pair having 3 KBD children and 3 healthy...
language: eng
source:
identifier: E-ISSN: 1932-6203 ; DOI: 10.1371/journal.pone.0103618
fulltext: fulltext_linktorsrc
issn:
  • 1932-6203
  • 19326203
url: Link


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titleGene expression analysis suggests bone development-related genes GDF5 and DIO2 are involved in the development of Kashin-Beck disease in children rather than adults
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descriptionTo investigate the differences in gene expression between children and adults with Kashin-Beck disease (KBD).12 children with KBD and 12 healthy children were selected and divided into 4 KBD vs. control pairs matched according to age and gender, with each pair having 3 KBD children and 3 healthy...
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titleGene expression analysis suggests bone development-related genes GDF5 and DIO2 are involved in the development of Kashin-Beck disease in children rather than adults
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To investigate the differences in gene expression between children and adults with Kashin-Beck disease (KBD).12 children with KBD and 12 healthy children were selected and divided into 4 KBD vs. control pairs matched according to age and gender, with each pair having 3 KBD children and 3 healthy...

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titleGene expression analysis suggests bone development-related genes GDF5 and DIO2 are involved in the development of Kashin-Beck disease in children rather than adults
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To investigate the differences in gene expression between children and adults with Kashin-Beck disease (KBD).12 children with KBD and 12 healthy children were selected and divided into 4 KBD vs. control pairs matched according to age and gender, with each pair having 3 KBD children and 3 healthy...

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