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A preliminary study of the novel antibiotic-loaded cement computer-aided design-articulating spacer for the treatment of periprosthetic knee infection

Abstract Background In comparison to static spacers, articulating spacers have been shown to result in a similar infection eradication rate in two-stage revision of periprosthetic knee infections. However, the optimal construct for articulating spacers has not been identified yet. The aim of this st... Full description

Journal Title: Journal of Orthopaedic Surgery and Research 01 May 2019, Vol.14(1), pp.1-11
Main Author: Chun-Hao Tsai
Other Authors: Horng-Chaung Hsu , Hui-Yi Chen , Yi-Chin Fong , Mao-Wang Ho , Chia-Huei Chou , Yi-Wen Chen , Ming-You Shie , Tsung-Li Lin
Format: Electronic Article Electronic Article
Language: English
Subjects:
ID: E-ISSN: 1749-799X ; DOI: 10.1186/s13018-019-1175-0
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title: A preliminary study of the novel antibiotic-loaded cement computer-aided design-articulating spacer for the treatment of periprosthetic knee infection
format: Article
creator:
  • Chun-Hao Tsai
  • Horng-Chaung Hsu
  • Hui-Yi Chen
  • Yi-Chin Fong
  • Mao-Wang Ho
  • Chia-Huei Chou
  • Yi-Wen Chen
  • Ming-You Shie
  • Tsung-Li Lin
subjects:
  • Computer-Aided Design
  • Articulating Spacers
  • Periprosthetic Knee Infection
  • Two-Staged Revision
  • Mechanical Complications
ispartof: Journal of Orthopaedic Surgery and Research, 01 May 2019, Vol.14(1), pp.1-11
description: Abstract Background In comparison to static spacers, articulating spacers have been shown to result in a similar infection eradication rate in two-stage revision of periprosthetic knee infections. However, the optimal construct for articulating spacers has not been identified yet. The aim of this study was to present a preliminary result of treatment for periprosthetic knee infection using a novel computer-aided design (CAD)-articulating spacer. Methods We retrospectively reviewed 32 consecutive cases of chronic periprosthetic knee infection occurring from January 2015 to December 2015. In these cases, we used an antibiotic-loaded, optimized CAD-articulating spacer based on the retrieved knee prosthesis. Evaluation included infection eradication rate, the Hospital of Special Surgery (HSS) knee score, range of motion (ROM), and spacer-related mechanical complications. All cases were regularly followed-up for 2 years minimum. Results Twenty-eight of 32 patients (87.5%) had infection...
language: eng
source:
identifier: E-ISSN: 1749-799X ; DOI: 10.1186/s13018-019-1175-0
fulltext: fulltext_linktorsrc
issn:
  • 1749-799X
  • 1749799X
url: Link


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titleA preliminary study of the novel antibiotic-loaded cement computer-aided design-articulating spacer for the treatment of periprosthetic knee infection
creatorChun-Hao Tsai ; Horng-Chaung Hsu ; Hui-Yi Chen ; Yi-Chin Fong ; Mao-Wang Ho ; Chia-Huei Chou ; Yi-Wen Chen ; Ming-You Shie ; Tsung-Li Lin
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identifierE-ISSN: 1749-799X ; DOI: 10.1186/s13018-019-1175-0
subjectComputer-Aided Design ; Articulating Spacers ; Periprosthetic Knee Infection ; Two-Staged Revision ; Mechanical Complications
descriptionAbstract Background In comparison to static spacers, articulating spacers have been shown to result in a similar infection eradication rate in two-stage revision of periprosthetic knee infections. However, the optimal construct for articulating spacers has not been identified yet. The aim of this study was to present a preliminary result of treatment for periprosthetic knee infection using a novel computer-aided design (CAD)-articulating spacer. Methods We retrospectively reviewed 32 consecutive cases of chronic periprosthetic knee infection occurring from January 2015 to December 2015. In these cases, we used an antibiotic-loaded, optimized CAD-articulating spacer based on the retrieved knee prosthesis. Evaluation included infection eradication rate, the Hospital of Special Surgery (HSS) knee score, range of motion (ROM), and spacer-related mechanical complications. All cases were regularly followed-up for 2 years minimum. Results Twenty-eight of 32 patients (87.5%) had infection...
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titleA preliminary study of the novel antibiotic-loaded cement computer-aided design-articulating spacer for the treatment of periprosthetic knee infection
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Abstract Background In comparison to static spacers, articulating spacers have been shown to result in a similar infection eradication rate in two-stage revision of periprosthetic knee infections. However, the optimal construct for articulating spacers has not been identified yet. The aim of this study was to present a preliminary result of treatment for periprosthetic knee infection using a novel computer-aided design (CAD)-articulating spacer. Methods We retrospectively reviewed 32 consecutive cases of chronic periprosthetic knee infection occurring from January 2015 to December 2015. In these cases, we used an antibiotic-loaded, optimized CAD-articulating spacer based on the retrieved knee prosthesis. Evaluation included infection eradication rate, the Hospital of Special Surgery (HSS) knee score, range of motion (ROM), and spacer-related mechanical complications. All cases were regularly followed-up for 2 years minimum. Results Twenty-eight of 32 patients (87.5%) had infection...

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Abstract Background In comparison to static spacers, articulating spacers have been shown to result in a similar infection eradication rate in two-stage revision of periprosthetic knee infections. However, the optimal construct for articulating spacers has not been identified yet. The aim of this study was to present a preliminary result of treatment for periprosthetic knee infection using a novel computer-aided design (CAD)-articulating spacer. Methods We retrospectively reviewed 32 consecutive cases of chronic periprosthetic knee infection occurring from January 2015 to December 2015. In these cases, we used an antibiotic-loaded, optimized CAD-articulating spacer based on the retrieved knee prosthesis. Evaluation included infection eradication rate, the Hospital of Special Surgery (HSS) knee score, range of motion (ROM), and spacer-related mechanical complications. All cases were regularly followed-up for 2 years minimum. Results Twenty-eight of 32 patients (87.5%) had infection...

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