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Rapid diagnosis of extra pulmonary tuberculosis by automated Xpert MTB/RIF assay

Although extra pulmonary tuberculosis accounts for only 10-15% of tuberculosis in India, they have high morbidity and mortality because of lack of good diagnostic methods. One of the recent molecular methods namely the Xpert MTB/RIF is a fully automated real time PCR system that detects M. tuberculo... Full description

Journal Title: BMC Infectious Diseases 01 May 2012, Vol.12(Suppl 1), p.P32
Main Author: Suzana Shirly
Other Authors: Shalini Baby , Rupali Priscilla , Venkatesh K , Christopher Dj , Michael Joy S
Format: Electronic Article Electronic Article
Language: English
Subjects:
ID: ISSN: 1471-2334 ; E-ISSN: 1471-2334 ; DOI: 10.1186/1471-2334-12-S1-P32
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title: Rapid diagnosis of extra pulmonary tuberculosis by automated Xpert MTB/RIF assay
format: Article
creator:
  • Suzana Shirly
  • Shalini Baby
  • Rupali Priscilla
  • Venkatesh K
  • Christopher Dj
  • Michael Joy S
subjects:
  • Medicine
ispartof: BMC Infectious Diseases, 01 May 2012, Vol.12(Suppl 1), p.P32
description: Although extra pulmonary tuberculosis accounts for only 10-15% of tuberculosis in India, they have high morbidity and mortality because of lack of good diagnostic methods. One of the recent molecular methods namely the Xpert MTB/RIF is a fully automated real time PCR system that detects M. tuberculosis (Mtb) complex and rifampicin resistance directly from clinical samples. This assay has been extensively evaluated in the diagnosis of pulmonary tuberculosis. The purpose of this study was to test the efficiency of this assay for the rapid and reliable diagnosis of extra pulmonary tuberculosis (EPTB).
language: eng
source:
identifier: ISSN: 1471-2334 ; E-ISSN: 1471-2334 ; DOI: 10.1186/1471-2334-12-S1-P32
fulltext: fulltext_linktorsrc
issn:
  • 1471-2334
  • 14712334
url: Link


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descriptionAlthough extra pulmonary tuberculosis accounts for only 10-15% of tuberculosis in India, they have high morbidity and mortality because of lack of good diagnostic methods. One of the recent molecular methods namely the Xpert MTB/RIF is a fully automated real time PCR system that detects M. tuberculosis (Mtb) complex and rifampicin resistance directly from clinical samples. This assay has been extensively evaluated in the diagnosis of pulmonary tuberculosis. The purpose of this study was to test the efficiency of this assay for the rapid and reliable diagnosis of extra pulmonary tuberculosis (EPTB).
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