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Effect of serum lipid concentrations on restenosis after successful de novo percutaneous transluminal coronary angioplasty in patients with total cholesterol 160 to 240 mg/dl and triglycerides <350 mg/dl

The present study is the first to demonstrate a possible role of triglycerides and HDL cholesterol in the multifactorial process of restenosis using validated computerized quantitative angiographic analysis in a group of patients with normal or only mildly elevated total and LDL cholesterol. The res... Full description

Journal Title: The American Journal of Cardiology 1995, Vol.75(14), pp.936-938
Main Author: Dzavik, Vladimir
Other Authors: Teo, Koon K , Yokoyama, Shinji , Modi, Renuca , Dinwoodie, Alison , Burton, Jeffrey R , Tymchak, Wayne J , Montague, Terrence J
Format: Electronic Article Electronic Article
Language: English
Subjects:
ID: ISSN: 0002-9149 ; E-ISSN: 1879-1913 ; DOI: 10.1016/S0002-9149(99)80691-2
Link: http://dx.doi.org/10.1016/S0002-9149(99)80691-2
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recordid: elsevier_sdoi_10_1016_S0002_9149_99_80691_2
title: Effect of serum lipid concentrations on restenosis after successful de novo percutaneous transluminal coronary angioplasty in patients with total cholesterol 160 to 240 mg/dl and triglycerides <350 mg/dl
format: Article
creator:
  • Dzavik, Vladimir
  • Teo, Koon K
  • Yokoyama, Shinji
  • Modi, Renuca
  • Dinwoodie, Alison
  • Burton, Jeffrey R
  • Tymchak, Wayne J
  • Montague, Terrence J
subjects:
  • Medicine
ispartof: The American Journal of Cardiology, 1995, Vol.75(14), pp.936-938
description: The present study is the first to demonstrate a possible role of triglycerides and HDL cholesterol in the multifactorial process of restenosis using validated computerized quantitative angiographic analysis in a group of patients with normal or only mildly elevated total and LDL cholesterol. The results of this study require validation by a prospective study in unselected consecutive patients undergoing PTCA. If these results are confirmed, a prospective randomized trial would then be appropriate to test strategies to lower the total/HDL cholesterol ratio, possibly using combination therapy targeting triglycerides and HDL cholesterol as well as LDL cholesterol.
language: eng
source:
identifier: ISSN: 0002-9149 ; E-ISSN: 1879-1913 ; DOI: 10.1016/S0002-9149(99)80691-2
fulltext: fulltext
issn:
  • 0002-9149
  • 00029149
  • 1879-1913
  • 18791913
url: Link


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titleEffect of serum lipid concentrations on restenosis after successful de novo percutaneous transluminal coronary angioplasty in patients with total cholesterol 160 to 240 mg/dl and triglycerides <350 mg/dl
creatorDzavik, Vladimir ; Teo, Koon K ; Yokoyama, Shinji ; Modi, Renuca ; Dinwoodie, Alison ; Burton, Jeffrey R ; Tymchak, Wayne J ; Montague, Terrence J
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descriptionThe present study is the first to demonstrate a possible role of triglycerides and HDL cholesterol in the multifactorial process of restenosis using validated computerized quantitative angiographic analysis in a group of patients with normal or only mildly elevated total and LDL cholesterol. The results of this study require validation by a prospective study in unselected consecutive patients undergoing PTCA. If these results are confirmed, a prospective randomized trial would then be appropriate to test strategies to lower the total/HDL cholesterol ratio, possibly using combination therapy targeting triglycerides and HDL cholesterol as well as LDL cholesterol.
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titleEffect of serum lipid concentrations on restenosis after successful de novo percutaneous transluminal coronary angioplasty in patients with total cholesterol 160 to 240 mg/dl and triglycerides <350 mg/dl
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The present study is the first to demonstrate a possible role of triglycerides and HDL cholesterol in the multifactorial process of restenosis using validated computerized quantitative angiographic analysis in a group of patients with normal or only mildly elevated total and LDL cholesterol. The results of this study require validation by a prospective study in unselected consecutive patients undergoing PTCA. If these results are confirmed, a prospective randomized trial would then be appropriate to test strategies to lower the total/HDL cholesterol ratio, possibly using combination therapy targeting triglycerides and HDL cholesterol as well as LDL cholesterol.

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titleEffect of serum lipid concentrations on restenosis after successful de novo percutaneous transluminal coronary angioplasty in patients with total cholesterol 160 to 240 mg/dl and triglycerides <350 mg/dl
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abstract

The present study is the first to demonstrate a possible role of triglycerides and HDL cholesterol in the multifactorial process of restenosis using validated computerized quantitative angiographic analysis in a group of patients with normal or only mildly elevated total and LDL cholesterol. The results of this study require validation by a prospective study in unselected consecutive patients undergoing PTCA. If these results are confirmed, a prospective randomized trial would then be appropriate to test strategies to lower the total/HDL cholesterol ratio, possibly using combination therapy targeting triglycerides and HDL cholesterol as well as LDL cholesterol.

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date1995-05-01