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The burden of HIV: insights from the Global Burden of Disease (GBD) Study 2010

Background To evaluate the global and country-level burden of HIV/AIDS relative to 291 other causes of disease burden from 1980 to 2010 using the Global Burden of Disease Study (GBD) 2010 as the vehicle for exploration. Methods HIV/AIDS burden estimates were derived as part of GBD 2010, a comprehens... Full description

Journal Title: The Lancet 17 June 2013, Vol.381, pp.S103-S103
Main Author: Ortblad, Katrina F
Other Authors: Lozano, Rafael , Murray, Christopher Jl
Format: Electronic Article Electronic Article
Language: English
Subjects:
ID: ISSN: 0140-6736 ; E-ISSN: 1474-547X ; DOI: 10.1016/S0140-6736(13)61357-4
Link: https://www.sciencedirect.com/science/article/pii/S0140673613613574
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recordid: elsevier_sdoi_10_1016_S0140_6736_13_61357_4
title: The burden of HIV: insights from the Global Burden of Disease (GBD) Study 2010
format: Article
creator:
  • Ortblad, Katrina F
  • Lozano, Rafael
  • Murray, Christopher Jl
subjects:
  • Medicine
ispartof: The Lancet, 17 June 2013, Vol.381, pp.S103-S103
description: Background To evaluate the global and country-level burden of HIV/AIDS relative to 291 other causes of disease burden from 1980 to 2010 using the Global Burden of Disease Study (GBD) 2010 as the vehicle for exploration. Methods HIV/AIDS burden estimates were derived as part of GBD 2010, a comprehensive assessment of the magnitude of 291 diseases and injuries from 1990 to 2010 for 187 countries. In GBD 2010, disability-adjusted life-years (DALYs) are used as the measurement of disease burden. DALY estimates for HIV/AIDS are derived from UNAIDS 2012 prevalence estimates, GBD 2010 disability weights, and custom mortality estimates. Findings Despite recent declines in global HIV/AIDS mortality, HIV/AIDS was still the fifth leading cause of global DALYs in 2010. The distribution of HIV/AIDS burden is not equal across demographics and regions. In 2010, HIV/AIDS ranked as the leading cause of DALYs for those aged 30-44 years in both males and females. In 2010, HIV/AIDS was also the leading cause of DALYs for 21 countries that fall into four distinctive blocks: eastern and southern Africa, central Africa, the Caribbean, and Thailand. While a majority of the HIV/AIDS DALYs are in high-burden countries, in 2010, 20 times 0% of the global HIV/AIDS burden was in countries where HIV/AIDS did not make the top ten leading causes of burden. Interpretation In the midst of a global economic recession, tracking the magnitude of the HIV/AIDS epidemic and its importance relative to other diseases and injuries is critical to effectively allocating limited resources and maintaining funding for effective HIV/AIDS interventions and treatments. Funding Bill & Melinda Gates Foundation.
language: eng
source:
identifier: ISSN: 0140-6736 ; E-ISSN: 1474-547X ; DOI: 10.1016/S0140-6736(13)61357-4
fulltext: fulltext
issn:
  • 0140-6736
  • 01406736
  • 1474-547X
  • 1474547X
url: Link


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titleThe burden of HIV: insights from the Global Burden of Disease (GBD) Study 2010
creatorOrtblad, Katrina F ; Lozano, Rafael ; Murray, Christopher Jl
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descriptionBackground To evaluate the global and country-level burden of HIV/AIDS relative to 291 other causes of disease burden from 1980 to 2010 using the Global Burden of Disease Study (GBD) 2010 as the vehicle for exploration. Methods HIV/AIDS burden estimates were derived as part of GBD 2010, a comprehensive assessment of the magnitude of 291 diseases and injuries from 1990 to 2010 for 187 countries. In GBD 2010, disability-adjusted life-years (DALYs) are used as the measurement of disease burden. DALY estimates for HIV/AIDS are derived from UNAIDS 2012 prevalence estimates, GBD 2010 disability weights, and custom mortality estimates. Findings Despite recent declines in global HIV/AIDS mortality, HIV/AIDS was still the fifth leading cause of global DALYs in 2010. The distribution of HIV/AIDS burden is not equal across demographics and regions. In 2010, HIV/AIDS ranked as the leading cause of DALYs for those aged 30-44 years in both males and females. In 2010, HIV/AIDS was also the leading cause of DALYs for 21 countries that fall into four distinctive blocks: eastern and southern Africa, central Africa, the Caribbean, and Thailand. While a majority of the HIV/AIDS DALYs are in high-burden countries, in 2010, 20 times 0% of the global HIV/AIDS burden was in countries where HIV/AIDS did not make the top ten leading causes of burden. Interpretation In the midst of a global economic recession, tracking the magnitude of the HIV/AIDS epidemic and its importance relative to other diseases and injuries is critical to effectively allocating limited resources and maintaining funding for effective HIV/AIDS interventions and treatments. Funding Bill & Melinda Gates Foundation.
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