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Vaccination with recombinant vaccinia virus vaccines expressing glycoprotein genes of pseudorabies virus in the presence of maternal immunity

Piglets which had received colostral antibody to pseudorabie virus (PRV) were divided into four groups and inoculated with a NYVAC vaccinia recombinant expressing glycoprotein gD of PRV, a NYVAC recombinant expressing glycoprotein gB of PRV, an inactivated PRV vaccine, or no vaccine. The piglets wer... Full description

Journal Title: Veterinary microbiology 1997, Vol.58 (2), p.93-103
Main Author: Brockmeier, Susan L
Other Authors: Lager, Kelly M , Mengeling, William L
Format: Electronic Article Electronic Article
Language: English
Subjects:
Animals
Biological and medical sciences
Colostrum - immunology
Female
Fundamental and applied biological sciences. Psychology
Herpesvirus 1, Suid - immunology
Herpesvirus 1, Suid - isolation & purification
Herpesvirus 1, Suid - pathogenicity
Immunity, Maternally-Acquired
Maternal immunity
Microbiology
NYVAC
Pseudorabies - immunology
Pseudorabies - prevention & control
Pseudorabies Vaccines
Pseudorabies virus
Swine
Time Factors
Vaccination
Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies
Vaccines, Inactivated
Vaccines, Synthetic
Viral Envelope Proteins - immunology
Viral Vaccines
Virology
Virulence
Virus Shedding
Publisher: Amsterdam: Elsevier B.V
ID: ISSN: 0378-1135
Zum Text:
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recordid: cdi_proquest_miscellaneous_79545720
title: Vaccination with recombinant vaccinia virus vaccines expressing glycoprotein genes of pseudorabies virus in the presence of maternal immunity
format: Article
creator:
  • Brockmeier, Susan L
  • Lager, Kelly M
  • Mengeling, William L
subjects:
  • Animals
  • Biological and medical sciences
  • Colostrum - immunology
  • Female
  • Fundamental and applied biological sciences. Psychology
  • Herpesvirus 1, Suid - immunology
  • Herpesvirus 1, Suid - isolation & purification
  • Herpesvirus 1, Suid - pathogenicity
  • Immunity, Maternally-Acquired
  • Maternal immunity
  • Microbiology
  • NYVAC
  • Pseudorabies - immunology
  • Pseudorabies - prevention & control
  • Pseudorabies Vaccines
  • Pseudorabies virus
  • Swine
  • Time Factors
  • Vaccination
  • Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies
  • Vaccines, Inactivated
  • Vaccines, Synthetic
  • Viral Envelope Proteins - immunology
  • Viral Vaccines
  • Virology
  • Virulence
  • Virus Shedding
ispartof: Veterinary microbiology, 1997, Vol.58 (2), p.93-103
description: Piglets which had received colostral antibody to pseudorabie virus (PRV) were divided into four groups and inoculated with a NYVAC vaccinia recombinant expressing glycoprotein gD of PRV, a NYVAC recombinant expressing glycoprotein gB of PRV, an inactivated PRV vaccine, or no vaccine. The piglets were vaccinated twice, 3 weeks apart, beginning at approximately 2 weeks of age and later challenged with virulent PRV oronasally. All three vaccines protected similarly when no maternal antibody was present. Although all three vaccines induced some active immunity in piglets with maternal antibody, piglets receiving the NYVAC/gB vaccine were the only ones protected similarly whether or not they had maternal antibodies to PRV.
language: eng
source:
identifier: ISSN: 0378-1135
fulltext: no_fulltext
issn:
  • 0378-1135
  • 1873-2542
url: Link


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titleVaccination with recombinant vaccinia virus vaccines expressing glycoprotein genes of pseudorabies virus in the presence of maternal immunity
creatorBrockmeier, Susan L ; Lager, Kelly M ; Mengeling, William L
creatorcontribBrockmeier, Susan L ; Lager, Kelly M ; Mengeling, William L
descriptionPiglets which had received colostral antibody to pseudorabie virus (PRV) were divided into four groups and inoculated with a NYVAC vaccinia recombinant expressing glycoprotein gD of PRV, a NYVAC recombinant expressing glycoprotein gB of PRV, an inactivated PRV vaccine, or no vaccine. The piglets were vaccinated twice, 3 weeks apart, beginning at approximately 2 weeks of age and later challenged with virulent PRV oronasally. All three vaccines protected similarly when no maternal antibody was present. Although all three vaccines induced some active immunity in piglets with maternal antibody, piglets receiving the NYVAC/gB vaccine were the only ones protected similarly whether or not they had maternal antibodies to PRV.
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subjectAnimals ; Biological and medical sciences ; Colostrum - immunology ; Female ; Fundamental and applied biological sciences. Psychology ; Herpesvirus 1, Suid - immunology ; Herpesvirus 1, Suid - isolation & purification ; Herpesvirus 1, Suid - pathogenicity ; Immunity, Maternally-Acquired ; Maternal immunity ; Microbiology ; NYVAC ; Pseudorabies - immunology ; Pseudorabies - prevention & control ; Pseudorabies Vaccines ; Pseudorabies virus ; Swine ; Time Factors ; Vaccination ; Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies ; Vaccines, Inactivated ; Vaccines, Synthetic ; Viral Envelope Proteins - immunology ; Viral Vaccines ; Virology ; Virulence ; Virus Shedding
ispartofVeterinary microbiology, 1997, Vol.58 (2), p.93-103
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descriptionPiglets which had received colostral antibody to pseudorabie virus (PRV) were divided into four groups and inoculated with a NYVAC vaccinia recombinant expressing glycoprotein gD of PRV, a NYVAC recombinant expressing glycoprotein gB of PRV, an inactivated PRV vaccine, or no vaccine. The piglets were vaccinated twice, 3 weeks apart, beginning at approximately 2 weeks of age and later challenged with virulent PRV oronasally. All three vaccines protected similarly when no maternal antibody was present. Although all three vaccines induced some active immunity in piglets with maternal antibody, piglets receiving the NYVAC/gB vaccine were the only ones protected similarly whether or not they had maternal antibodies to PRV.
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1Biological and medical sciences
2Colostrum - immunology
3Female
4Fundamental and applied biological sciences. Psychology
5Herpesvirus 1, Suid - immunology
6Herpesvirus 1, Suid - isolation & purification
7Herpesvirus 1, Suid - pathogenicity
8Immunity, Maternally-Acquired
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10Microbiology
11NYVAC
12Pseudorabies - immunology
13Pseudorabies - prevention & control
14Pseudorabies Vaccines
15Pseudorabies virus
16Swine
17Time Factors
18Vaccination
19Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies
20Vaccines, Inactivated
21Vaccines, Synthetic
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titleVaccination with recombinant vaccinia virus vaccines expressing glycoprotein genes of pseudorabies virus in the presence of maternal immunity
authorBrockmeier, Susan L ; Lager, Kelly M ; Mengeling, William L
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1Biological and medical sciences
2Colostrum - immunology
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6Herpesvirus 1, Suid - isolation & purification
7Herpesvirus 1, Suid - pathogenicity
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13Pseudorabies - prevention & control
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15Pseudorabies virus
16Swine
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20Vaccines, Inactivated
21Vaccines, Synthetic
22Viral Envelope Proteins - immunology
23Viral Vaccines
24Virology
25Virulence
26Virus Shedding
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abstractPiglets which had received colostral antibody to pseudorabie virus (PRV) were divided into four groups and inoculated with a NYVAC vaccinia recombinant expressing glycoprotein gD of PRV, a NYVAC recombinant expressing glycoprotein gB of PRV, an inactivated PRV vaccine, or no vaccine. The piglets were vaccinated twice, 3 weeks apart, beginning at approximately 2 weeks of age and later challenged with virulent PRV oronasally. All three vaccines protected similarly when no maternal antibody was present. Although all three vaccines induced some active immunity in piglets with maternal antibody, piglets receiving the NYVAC/gB vaccine were the only ones protected similarly whether or not they had maternal antibodies to PRV.
copAmsterdam
pubElsevier B.V
pmid9453121
doi10.1016/S0378-1135(97)00161-2