schliessen

Filtern

 

Bibliotheken

K-targeted strategy for isolation of phenolic alkaloids of Nelumbo nucifera Gaertn by counter-current chromatography using lysine as a pH regulator

Counter-current chromatography (CCC) is an efficient liquid-liquid partition chromatography technique without support matrix. Despite there are many significant advancements in the CCC separation of natural products especially for non-ionic neutral compounds, CCC isolation of ionic compounds includi... Full description

Journal Title: Journal of Chromatography A 24 March 2017, Vol.1490, pp.115-125
Main Author: Wang, Yanyan
Other Authors: Zhang, Lihong , Zhou, Hui , Guo, Xiuyun , Wu, Shihua
Format: Electronic Article Electronic Article
Language: English
Subjects:
ID: ISSN: 0021-9673 ; DOI: 10.1016/j.chroma.2017.02.022
Link: https://www.sciencedirect.com/science/article/pii/S0021967317302455
Zum Text:
SendSend as email Add to Book BagAdd to Book Bag
Staff View
recordid: elsevier_sdoi_10_1016_j_chroma_2017_02_022
title: K-targeted strategy for isolation of phenolic alkaloids of Nelumbo nucifera Gaertn by counter-current chromatography using lysine as a pH regulator
format: Article
creator:
  • Wang, Yanyan
  • Zhang, Lihong
  • Zhou, Hui
  • Guo, Xiuyun
  • Wu, Shihua
subjects:
  • Count-Current Chromatography
  • K-Targeted Strategy
  • Lysine
  • Neferine
  • Peak Skewing
  • Phenolic Alkaloids
  • Chemistry
ispartof: Journal of Chromatography A, 24 March 2017, Vol.1490, pp.115-125
description: Counter-current chromatography (CCC) is an efficient liquid-liquid partition chromatography technique without support matrix. Despite there are many significant advancements in the CCC separation of natural products especially for non-ionic neutral compounds, CCC isolation of ionic compounds including alkaloids is still a challenging process guide by classical partition coefficients ( ) or distribution ratio ( ) because their partition coefficient could not be equal to distribution ratio in common ionic conditions. Here, taking the extract of embryo of the seed of Gaertn as sample, we introduced a modified -targeted strategy for isolation of phenolic alkaloids by use of lysine as a pH regulator. The results indicated that if the mass of basic regulators such as aqueous ammonia and lysine added into the solvent system were high enough to inhibit the ionization of the targeted alkaloids, the distribution...
language: eng
source:
identifier: ISSN: 0021-9673 ; DOI: 10.1016/j.chroma.2017.02.022
fulltext: fulltext
issn:
  • 0021-9673
  • 00219673
url: Link


@attributes
ID679733369
RANK0.07
NO1
SEARCH_ENGINEprimo_central_multiple_fe
SEARCH_ENGINE_TYPEPrimo Central Search Engine
LOCALfalse
PrimoNMBib
record
control
sourcerecordiddoi_10_1016_j_chroma_2017_02_022
sourceidelsevier_s
recordidTN_elsevier_sdoi_10_1016_j_chroma_2017_02_022
sourcesystemPC
dbid
0--K
1--M
2.~1
31B1
41RT
51~.
6457
74G.
87-5
98P~
109JN
11AABNK
12AAEDT
13AAKOC
14AAOAW
15AAQFI
16AARLI
17ABFNM
18ABYKQ
19ACDAQ
20ACRLP
21ADECG
22AEKER
23AFKWA
24AFTJW
25AGHFR
26AGUBO
27AGYEJ
28AIKHN
29AITUG
30AJBFU
31AJOXV
32AJSZI
33AMFUW
34BLXMC
35EO8
36EO9
37EP2
38EP3
39FDB
40FIRID
41FLBIZ
42FNPLU
43G-Q
44GBLVA
45J1W
46KOM
47OAUVE
48P-8
49P-9
50PC.
51Q38
52RPZ
53SCC
54SCH
55SDF
56SDG
57SDP
58SES
59SPC
60SSK
61SSZ
62T5K
63~G-
pqid1872575094
galeid485222434
display
typearticle
titleK-targeted strategy for isolation of phenolic alkaloids of Nelumbo nucifera Gaertn by counter-current chromatography using lysine as a pH regulator
creatorWang, Yanyan ; Zhang, Lihong ; Zhou, Hui ; Guo, Xiuyun ; Wu, Shihua
ispartofJournal of Chromatography A, 24 March 2017, Vol.1490, pp.115-125
identifierISSN: 0021-9673 ; DOI: 10.1016/j.chroma.2017.02.022
subjectCount-Current Chromatography ; K-Targeted Strategy ; Lysine ; Neferine ; Peak Skewing ; Phenolic Alkaloids ; Chemistry
descriptionCounter-current chromatography (CCC) is an efficient liquid-liquid partition chromatography technique without support matrix. Despite there are many significant advancements in the CCC separation of natural products especially for non-ionic neutral compounds, CCC isolation of ionic compounds including alkaloids is still a challenging process guide by classical partition coefficients ( ) or distribution ratio ( ) because their partition coefficient could not be equal to distribution ratio in common ionic conditions. Here, taking the extract of embryo of the seed of Gaertn as sample, we introduced a modified -targeted strategy for isolation of phenolic alkaloids by use of lysine as a pH regulator. The results indicated that if the mass of basic regulators such as aqueous ammonia and lysine added into the solvent system were high enough to inhibit the ionization of the targeted alkaloids, the distribution...
languageeng
source
version6
lds50peer_reviewed
links
openurl$$Topenurl_article
openurlfulltext$$Topenurlfull_article
backlink$$Uhttps://www.sciencedirect.com/science/article/pii/S0021967317302455$$EView_record_in_ScienceDirect_(Access_to_full_text_may_be_restricted)
search
creatorcontrib
0Wang, Yanyan
1Zhang, Lihong
2Zhou, Hui
3Guo, Xiuyun
4Wu, Shihua
titleK-targeted strategy for isolation of phenolic alkaloids of Nelumbo nucifera Gaertn by counter-current chromatography using lysine as a pH regulator
description
subject
0Count-Current Chromatography
1K-Targeted Strategy
2Lysine
3Neferine
4Peak Skewing
5Phenolic Alkaloids
6Chemistry
general
0English
1Elsevier B.V
210.1016/j.chroma.2017.02.022
3ScienceDirect (Elsevier)
4ScienceDirect Journals (Elsevier)
sourceidelsevier_s
recordidelsevier_sdoi_10_1016_j_chroma_2017_02_022
issn
00021-9673
100219673
rsrctypearticle
creationdate2017
addtitleJournal of Chromatography A
searchscope
0elsevier_full
1elsevier2
scope
0elsevier_full
1elsevier2
lsr44$$EView_record_in_ScienceDirect_(Access_to_full_text_may_be_restricted)
tmp01ScienceDirect Journals (Elsevier)
tmp02
0--K
1--M
2.~1
31B1
41RT
51~.
6457
74G.
87-5
98P~
109JN
11AABNK
12AAEDT
13AAKOC
14AAOAW
15AAQFI
16AARLI
17ABFNM
18ABYKQ
19ACDAQ
20ACRLP
21ADECG
22AEKER
23AFKWA
24AFTJW
25AGHFR
26AGUBO
27AGYEJ
28AIKHN
29AITUG
30AJBFU
31AJOXV
32AJSZI
33AMFUW
34BLXMC
35EO8
36EO9
37EP2
38EP3
39FDB
40FIRID
41FLBIZ
42FNPLU
43G-Q
44GBLVA
45J1W
46KOM
47OAUVE
48P-8
49P-9
50PC.
51Q38
52RPZ
53SCC
54SCH
55SDF
56SDG
57SDP
58SES
59SPC
60SSK
61SSZ
62T5K
63~G-
startdate20170324
enddate20170324
lsr40Journal of Chromatography A, 24 March 2017, Vol.1490, pp.115-125
doi10.1016/j.chroma.2017.02.022
citationpf 115 pt 125 vol 1490
lsr30VSR-Enriched:[eissn, pqid, galeid]
sort
titleK-targeted strategy for isolation of phenolic alkaloids of Nelumbo nucifera Gaertn by counter-current chromatography using lysine as a pH regulator
authorWang, Yanyan ; Zhang, Lihong ; Zhou, Hui ; Guo, Xiuyun ; Wu, Shihua
creationdate20170324
lso0120170324
facets
frbrgroupid7581486304399589772
frbrtype5
newrecords20190904
languageeng
topic
0Count-Current Chromatography
1K-Targeted Strategy
2Lysine
3Neferine
4Peak Skewing
5Phenolic Alkaloids
6Chemistry
collectionScienceDirect (Elsevier)
prefilterarticles
rsrctypearticles
creatorcontrib
0Wang, Yanyan
1Zhang, Lihong
2Zhou, Hui
3Guo, Xiuyun
4Wu, Shihua
jtitleJournal of Chromatography A
creationdate2017
toplevelpeer_reviewed
delivery
delcategoryRemote Search Resource
fulltextfulltext
addata
aulast
0Wang
1Zhang
2Zhou
3Guo
4Wu
aufirst
0Yanyan
1Lihong
2Hui
3Xiuyun
4Shihua
auinitY
auinit1Y
au
0Wang, Yanyan
1Zhang, Lihong
2Zhou, Hui
3Guo, Xiuyun
4Wu, Shihua
atitleK-targeted strategy for isolation of phenolic alkaloids of Nelumbo nucifera Gaertn by counter-current chromatography using lysine as a pH regulator
jtitleJournal of Chromatography A
risdate20170324
volume1490
spage115
epage125
pages115-125
issn0021-9673
formatjournal
genrearticle
ristypeJOUR
abstract
pubElsevier B.V
doi10.1016/j.chroma.2017.02.022
lad01Journal of Chromatography A
eissn18733778
date2017-03-24